Unraveling the anxious mind: Anxiety, worry, and frontal engagement in sustained attention versus off-task processing

Cerebral Cortex

Volumn 25, Issue 3, 2015, Pages 609-618

  Forster, Sophie ^a   Elizalde, Anwar O Nunez ^a   Castle, Elizabeth ^a   Bishop, Sonia J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Anxiety; frontal function; off task thought; sustained attention; worry

Indexed keywords

ADULT; ALERTNESS; ANTERIOR CINGULATE; ANXIETY; ARTICLE; BRAIN FUNCTION; CLINICAL ASSESSMENT; CONNECTOME; DEFAULT MODE NETWORK; DISEASE ASSOCIATION; ELECTROENCEPHALOGRAM; FEMALE; FOLLOW UP; FRONTAL CORTEX; FRONTAL FUNCTION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; HUMAN EXPERIMENT; JOINT FUNCTION; MALE; MENTAL HEALTH CARE; NERVE STIMULATION; NORMAL HUMAN; PATIENT WORRY; POSTERIOR CINGULATE; PREFRONTAL CORTEX; PRIORITY JOURNAL; SELECTIVE ATTENTION; STATE TRAIT ANXIETY INVENTORY; STRIATE CORTEX; SUSTAINED ATTENTION; TASK PERFORMANCE; THALAMUS; YOUNG ADULT; ANXIETY DISORDER; ATTENTION; BRAIN MAPPING; CINGULATE GYRUS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; ANXIETY DISORDERS; ATTENTION; BRAIN MAPPING; FEMALE; GYRUS CINGULI; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PREFRONTAL CORTEX; YOUNG ADULT;

EID: 84928348212     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bht248     Document Type: Article

References (42)

1. Aron AR. 2011. From reactive to proactive and selective control: developing a richer model for stopping inappropriate responses. Biol Psychiatry. 69:55-68
2. Barron E, Riby LM, Greer J, Smallwood J. 2011. Absorbed in thought: the effect of mind wandering on the processing of relevant and irrelevant events. Psychol Sci. 22(5):596-601
3. Beiser DG, Houk JC. 1998. Model of cortical-basal ganglionic processing: encoding the serial order of sensory events. J Neurophy. 796:3168-3188
4. Bieling PJ, Antony MM, Swinson RP. 1998. The state-trait anxiety inventory, trait version: structure and content re-examined. Behav Res Ther. 36:777-788
5. Bishop SJ. 2009. Trait anxiety and impoverished prefrontal control of attention. Nat Neurosci. 12:92-98
6. Bishop SJ, Duncan J, Brett M, Lawrence A. 2004. Prefrontal cortical function and anxiety: controlling attention to threat-related stimuli. Nat Neurosci. 7:184-188
7. Bishop SJ, Fossella J, Croucher C, Duncan J. 2008. COMT Val 158 met genotype affects recruitment of neural mechanisms supporting fluid intelligence. Cereb Cortex. 18:2132-2140
8. Bishop SJ, Jenkins R, Lawrence A. 2007. The neural processing of task-irrelevant fearful faces: effects of perceptual load and individual differences in trait and state anxiety. Cereb Cortex. 17:1595-1603
9. Borkovec TD, Robinson E, Pruzinsky T, DePree JA. 1983. Preliminary exploration of worry: some characteristics and processes. Behav ResTher. 21:9-16
10. Botvinick MM. 2007. Conflict monitoring and decision making: reconciling two perspectives on anterior cingulate function. J Cogn Affect Behav Neurosci. 7:356-366
11. Botvinick MM, Nystrom L, Fissell K, Carter CS, Cohen JD. 1999. Conflict monitoring vs. selection-for-action in anterior cingulate cortex. Nature. 402:179-181
12. Braver TS, Barch DM. 2006. Extracting core components of cognitive control. Trends Cogn Sci. 10(12):529-532
13. Braver TS, Gray JR, Burgess GC. 2007. Explaining the many varieties of working memory variation: dual mechanisms of cognitive control Chapter 4. In: Conway ARA, Jarrold C, Kane MJ, Miyake A, Towse JN, editors. Variation in Working Memory. Oxford, UK: Oxford University Press. p. 76-106
14. Brett M, Anton JL, Valabregue R, Poline JB. 2002. Region of interest analysis using an SPM toolbox. Neuroimage. 16(Suppl. 1):1141
15. Carp J. 2011. Optimizing the order of operations for movement scrubbing: comment on Power et al. Neuroimage. 76:436-438
16. Carter CS, Macdonald AM, Botvinick M, Ross LL, Stenger VA, Noll D, Cohen JD. 2000. Parsing executive processes: strategic vs. evaluative functions of the anterior cingulate cortex. Proc Natl Acad Sci U S A. 97:1944-1948
17. Chambers JA, Power KG, Durham RC. 2004. The relationship between trait vulnerability and anxiety and depressive diagnoses at longterm followup of generalized anxiety disorder. J Anxiety Disord. 18:587-607
18. Christoff K, Gordon AM, Smallwood J, Smith R, Schooler JW. 2009. Experience sampling during fMRI reveals default network and executive system contributions to mind wandering. Proc Natl Acad Sci. 106(21):8719-8724
19. Duncan J, Owen AM. 2000. Common regions of the human frontal lobe recruited by diverse cognitive demands. Trends Neurosci. 10:475-483
20. Eysenck MW. 1979. Anxiety, learning and memory: A reconceptualization. J Res Pers. 13(4):363-385
21. Eysenck MW, Calvo MG. 1992. Anxiety and performance: the processing efficiency theory. Cogn Emo. 6:409-434
22. Eysenck MW, Derakshan N, Santos R, Calvo MG. 2007. Anxiety and cognitive performance: attentional control theory. Emotion. 7:336-353
23. Fassbender C, Murphy K, Foxe J, Wylie G, Javitt D, Robertson IH, Garavan H. 2004. A topography of executive functions and their interactions revealed by functional magnetic resonance imaging. Brain Res Cogn Brain Res. 20:132-143
24. Frank MJ, Loughry B, O'Reilly RC. 2001. Interactions between frontal cortex and basal ganglia in working memory: A computational model. Cogn Affect Behav Neurosci. 1:137-160
25. Friston KJ. 1997. Analyzing brain images: principles and overview. In: Frackowiak RSJ, Friston KJ, Frith C, Dolan R, Mazziotta JC, editors. Human Brain Function. Salt Lake City, UT: Academic Press USA. p. 25-41
26. Gitelman DR, Penny WD, Ashburner J, Friston KJ. 2003. Modeling regional and psychophysiologic interactions in fMRI: the importance of hemodynamic deconvolution. NeuroImage. 19:200-207
27. Goel V, Dolan RJ. 2003. Reciprocal neural response within lateral and ventral medial prefrontal cortex during hot and cold reasoning. NeuroImage. 20(4):2314-2321
28. MacLeod C, Mathews A. 1988. Anxiety and the allocation of attention to threat. Q J Exp Psychol. 40:653-670
29. Mathews A, Mackintosh B. 1998. A cognitive model of selective processing in anxiety. Cogn Ther Res. 22:539-560
30. McVay JC, Kane MC. 2010. Does mind wandering reflect executive function or executive failure? Comment on Smallwood and Schooler (2006) andWatkins (2008). Psychol Bull. 136:188-197
31. Meyer TJ, Miller ML, Metzger RL, Borkovec TD. 1990. Development and validation of the penn state worry questionnaire. Behav Res Ther. 28:487-495
32. Mogg K, Bradley BP. 1998. A cognitive-motivational analysis of anxiety. Behav Res Ther. 36:809-848
33. Morishima Y, Okuda J, Sakai K. 2010. Reactive mechanism of cognitive control system. Cereb Cortex. 20(11):2675-2683
34. Nachev P. 2006. Cognition and medial frontal cortex in health and disease. Curr Opin Neurol. 19:587-592
35. Olatunji BO, Wolitzky-Taylor KB, Sawchuk CN, Ciesielski BG. 2011. Worry and the anxiety disorders: A metaanalytic synthesis of specificity to GAD. App Prev Psychol. 14:1-24
36. Plehn K, Peterson RA. 2002. Anxiety sensitivity as a predictor of the development of panic symptoms, panic attacks, and panic disorder: A prospective study. J Anxiety Disord. 16: 455-474
37. Power JD, Barnes KA, Snyder AZ, Schlaggar BL, Petersen SE. 2012. Spurious but systematic correlations in functional connectivity MRI networks arise from subject motion. Neuroimage. 59(3): 2142-2154
38. Richards A, Millwood B. 1989. Colour-identification of differentially valenced words in anxiety. Cognition Emotion. 3:171-176
39. Robertson TH, Manly T, Andrade J, Baddeley BT, Yiend J. 1997. "Oops": performance correlates of everyday attentional failures in traumatic brain injured and normal subjects. Neuropsychologica. 356:747-758
40. Spielberger CD, Gorsuch RL, Lushene PR, Vagg PR, Jacobs AG. 1983. Manual for the State-Trait Anxiety Inventory Form Y. Palo Alto: Consulting Psychologists Press, Inc
41. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazover B, Joliot M. 2002. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. NeuroImage. 15:273-289
42. Vul E, Harris C, Winkielman P, Pashler H. 2009. Puzzlingly high correlations in fMRI studies of emotion, personality, and social cognition. Persp Psych Sci. 4:274-290.