Role of PTEN in neutrophil extracellular trap formation

Molecular Immunology

Volumn 66, Issue 2, 2015, Pages 319-324

  Teimourian, Shahram ^a,b,c   Moghanloo, Ehsan ^b,c,d  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d KASHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Autophagy; NETosis; Neutrophil extracellular traps; PTEN

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; MTOR PROTEIN, HUMAN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; PTEN PROTEIN, HUMAN; SMALL INTERFERING RNA; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR TRAP; GENE OVEREXPRESSION; GENE SILENCING; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL DEATH; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HL 60 CELL LINE; HUMAN; IMMUNOLOGY; PATHOLOGY; SIGNAL TRANSDUCTION;

CELL DEATH; CELL DIFFERENTIATION; CLASS I PHOSPHATIDYLINOSITOL 3-KINASES; EXTRACELLULAR TRAPS; GENE EXPRESSION REGULATION; HL-60 CELLS; HUMANS; NEUTROPHILS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TOR SERINE-THREONINE KINASES;

EID: 84928337247     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.03.251     Document Type: Article

References (23)

1. Amulic B., Hayes G. Neutrophil extracellular traps. Curr. Biol. 2011, 21(9):R297-R298.
2. Arico S., Petiot A., Bauvy C., Dubbelhuis P.F., Meijer A.J., Codogno P., Ogier-Denis E. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway. J. Biol. Chem. 2001, 276:35243-35246.
3. Bianchi M., Hakkim A., Brinkmann V., Siler U., Seger R.A., Zychlinsky A., Reichenbach J. Restoration of NET formation by gene therapy in CGD controls aspergillosis. Blood 2009, 114:2619-2622.
4. Brinkmann V., Ulrike R., Christian G., Beatrix F., Yvonne U., David S.W., Yvette W., Arturo Z. Neutrophil extracellular traps kill bacteria. Science 2004, 303:1532-1535.
5. Dworski R., Simon H.U., Hoskins A., Yousefi S. Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways. J. Allergy Clin. Immunol. 2011, 127:1260-1266.
6. Fuchs T.A., Abed U., Goosmann C., Hurwitz R., Schulze I., Wahn V., Weinrauch Y., Brinkmann V., Zychlinsky A. Novel cell death program leads to neutrophil extracellular traps. J. Cell Biol. 2007, 176:231-241.
7. Georgescu M.M. PTEN tumor suppressor network in PI3K-Akt pathway control. Genes Cancer 2010, 1:1170-1177.
8. Gupta A.K., Hasler P., Holzgreve W., Gebhardt S., Hahn S. Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia. Hum. Immunol. 2005, 66:1146-1154.
9. Hollander M.C., Blumenthal G.M., Dennis P.A. PTEN loss in the continuum of common cancers, rare syndromes and mouse models. Nat. Rev. Cancer 2011, 11:289-301.
10. Itakura A., McCarty O.J. Pivotal role for the mTOR pathway in the formation of neutrophil extracellular traps via regulation of autophagy. Am. J. Physiol. Cell Physiol. 2013, 305:C348-C354.
11. Jaillon S., Galdiero M.R., Del Prete D., Cassatella M.A., Garlanda C., Mantovani A. Neutrophils in innate and adaptive immunity. Semin. Immunopathol. 2013, 35:377-394.
12. Keshari R.S., Verma A., Barthwal M.K., Dikshit M. Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils. J. Cell. Biochem. 2013, 114:532-540.
13. Kumar V., Sharma A. Neutrophils: cinderella of innate immune system. Int. Immunopharmacol. 2010, 10:1325-1334.
14. Leshner M., Wang S., Lewis C., Zheng H., Chen X.A., Santy L., Wang Y. PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures. Front. Immunol. 2012, 3:307.
15. Menegazzo L., Ciciliot S., Poncina N., Mazzucato M., Persano M., Bonora B., Albiero M., Vigili de Kreutzenberg S., Avogaro A., Fadini G.P. NETosis is induced by high glucose and associated with type 2 diabetes. Acta Diabetol. 2014, (November).
16. Mizushima N., Hara T. Intracellular quality control by autophagy: how does autophagy prevent neurodegeneration?. Autophagy 2006, 2:302-304.
17. Pelletier M., Girard D. Interleukin-15 increases neutrophil adhesion onto human respiratory epithelial A549 cells and attracts neutrophils in vivo. Clin. Exp. Immunol. 2005, 141:315-325.
18. Remijsen Q., Vanden Berghe T., Wirawan E., Asselbergh B., Parthoens E., De Rycke R., Noppen S., Delforge M., Willems J., Vandenabeele P. Neutrophil extracellular trap cell death requires both autophagy and superoxide generation. Cell Res. 2011, 21:290-304.
19. Ueno T., Sato W., Horie Y., Komatsu M., Tanida I., Yoshida M., Ohshima S., Mak T.W., Watanabe S., Kominami E. Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy 2008, 4:692-700.
20. Urban C.F., Ermert D., Schmid M., Abu-Abed U., Goosmann C., Nacken W., Brinkmann V., Jungblut P.R., Zychlinsky A. Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. PLoS Pathog. 2009, 5:e1000639.
21. Wang Y., Li M., Stadler S., Correll S., Li P., Wang D., et al. Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation. J. Cell Biol. 2009, 184:205-213.
22. Yang C.T., Cambier C.J., Davis J.M., Hall C.J., Crosier P.S., Ramakrishnan L. Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages. Cell Host Microbe 2012, 12:301-312.
23. Yu Y., Su K. Neutrophil extracellular traps and systemic lupus erythematosus. J. Clin. Cell Immunol. 2013, 4:139.