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Volumn 15, Issue 5, 2015, Pages 253-261

Impact of bone marrow pathology on the clinical management of Philadelphia chromosome - Negative myeloproliferative neoplasms

Author keywords

Bone marrow fibrosis; Essential thrombocythemia; Polycythemia vera; Primary myelofibrosis; Ruxolitinib

Indexed keywords

ANTIFIBROTIC AGENT; ANTIINFLAMMATORY AGENT; COLLAGEN; JANUS KINASE; JANUS KINASE INHIBITOR; RETICULIN; RUXOLITINIB; STAT PROTEIN; PYRAZOLE DERIVATIVE;

EID: 84928304478     PISSN: 21522650     EISSN: 21522669     Source Type: Journal    
DOI: 10.1016/j.clml.2014.11.002     Document Type: Review
Times cited : (17)

References (83)
  • 1
    • 34548042964 scopus 로고    scopus 로고
    • Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel
    • A. Tefferi, J. Thiele, and A. Orazi et al. Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel Blood 110 2007 1092 1097
    • (2007) Blood , vol.110 , pp. 1092-1097
    • Tefferi, A.1    Thiele, J.2    Orazi, A.3
  • 2
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
    • J.W. Vardiman, J. Thiele, and D.A. Arber et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes Blood 114 2009 937 951
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 3
    • 84857893209 scopus 로고    scopus 로고
    • Genetic and epigenetic complexity in myeloproliferative neoplasms
    • N.C. Cross Genetic and epigenetic complexity in myeloproliferative neoplasms Hematology Am Soc Hematol Educ Program 2011 2011 208 214
    • (2011) Hematology Am Soc Hematol Educ Program , vol.2011 , pp. 208-214
    • Cross, N.C.1
  • 4
    • 84901714382 scopus 로고    scopus 로고
    • Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis
    • R. Rampal, F. Al-Shahrour, and O. Abdel-Wahab et al. Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis Blood 123 2014 e123 e133
    • (2014) Blood , vol.123 , pp. e123-e133
    • Rampal, R.1    Al-Shahrour, F.2    Abdel-Wahab, O.3
  • 5
    • 84890328032 scopus 로고    scopus 로고
    • Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2
    • J. Nangalia, C.E. Massie, and E.J. Baxter et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2 N Engl J Med 369 2013 2391 2405
    • (2013) N Engl J Med , vol.369 , pp. 2391-2405
    • Nangalia, J.1    Massie, C.E.2    Baxter, E.J.3
  • 6
    • 84890372480 scopus 로고    scopus 로고
    • Somatic mutations of calreticulin in myeloproliferative neoplasms
    • T. Klampfl, H. Gisslinger, and A.S. Harutyunyan et al. Somatic mutations of calreticulin in myeloproliferative neoplasms N Engl J Med 369 2013 2379 2390
    • (2013) N Engl J Med , vol.369 , pp. 2379-2390
    • Klampfl, T.1    Gisslinger, H.2    Harutyunyan, A.S.3
  • 7
    • 84899065964 scopus 로고    scopus 로고
    • Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms
    • P. Lundberg, A. Karow, and R. Nienhold et al. Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms Blood 123 2014 2220 2228
    • (2014) Blood , vol.123 , pp. 2220-2228
    • Lundberg, P.1    Karow, A.2    Nienhold, R.3
  • 8
    • 77956439565 scopus 로고    scopus 로고
    • A prospective study of 338 patients with polycythemia vera: the impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications
    • F. Passamonti, E. Rumi, and D. Pietra et al. A prospective study of 338 patients with polycythemia vera: the impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications Leukemia 24 2010 1574 1579
    • (2010) Leukemia , vol.24 , pp. 1574-1579
    • Passamonti, F.1    Rumi, E.2    Pietra, D.3
  • 9
    • 84897517940 scopus 로고    scopus 로고
    • JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes
    • E. Rumi, D. Pietra, and V. Ferretti et al. JAK2 or CALR mutation status defines subtypes of essential thrombocythemia with substantially different clinical course and outcomes Blood 123 2014 1544 1551
    • (2014) Blood , vol.123 , pp. 1544-1551
    • Rumi, E.1    Pietra, D.2    Ferretti, V.3
  • 10
    • 84880595307 scopus 로고    scopus 로고
    • Acquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasms
    • E. Rumi, D. Pietra, and P. Guglielmelli et al. Acquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasms Blood 121 2013 4388 4395
    • (2013) Blood , vol.121 , pp. 4388-4395
    • Rumi, E.1    Pietra, D.2    Guglielmelli, P.3
  • 11
    • 84904056081 scopus 로고    scopus 로고
    • CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: an international study of 570 patients
    • A. Tefferi, P. Guglielmelli, and T.L. Lasho et al. CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: an international study of 570 patients Leukemia 28 2014 1494 1500
    • (2014) Leukemia , vol.28 , pp. 1494-1500
    • Tefferi, A.1    Guglielmelli, P.2    Lasho, T.L.3
  • 12
    • 84903648668 scopus 로고    scopus 로고
    • Distinct clinical characteristics in myeloproliferative neoplasms with calreticulin mutations
    • H. Andrikovics, T. Krahling, and K. Balassa et al. Distinct clinical characteristics in myeloproliferative neoplasms with calreticulin mutations Haematologica 99 2014 1184 1190
    • (2014) Haematologica , vol.99 , pp. 1184-1190
    • Andrikovics, H.1    Krahling, T.2    Balassa, K.3
  • 13
    • 84904042955 scopus 로고    scopus 로고
    • CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons
    • A. Tefferi, T.L. Lasho, and C.M. Finke et al. CALR vs JAK2 vs MPL-mutated or triple-negative myelofibrosis: clinical, cytogenetic and molecular comparisons Leukemia 28 2014 1472 1477
    • (2014) Leukemia , vol.28 , pp. 1472-1477
    • Tefferi, A.1    Lasho, T.L.2    Finke, C.M.3
  • 14
    • 84883742034 scopus 로고    scopus 로고
    • Mutations and prognosis in primary myelofibrosis
    • A.M. Vannucchi, T.L. Lasho, and P. Guglielmelli et al. Mutations and prognosis in primary myelofibrosis Leukemia 27 2013 1861 1869
    • (2013) Leukemia , vol.27 , pp. 1861-1869
    • Vannucchi, A.M.1    Lasho, T.L.2    Guglielmelli, P.3
  • 15
    • 84857997263 scopus 로고    scopus 로고
    • IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F
    • A. Tefferi, T. Jimma, and N.H. Sulai et al. IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F Leukemia 26 2012 475 480
    • (2012) Leukemia , vol.26 , pp. 475-480
    • Tefferi, A.1    Jimma, T.2    Sulai, N.H.3
  • 16
    • 84889078595 scopus 로고    scopus 로고
    • Morphologic and cytogenetic differences between post-polycythemic myelofibrosis and primary myelofibrosis in fibrotic stage
    • L. Boiocchi, S. Mathew, and U. Gianelli et al. Morphologic and cytogenetic differences between post-polycythemic myelofibrosis and primary myelofibrosis in fibrotic stage Mod Pathol 26 2013 1577 1585
    • (2013) Mod Pathol , vol.26 , pp. 1577-1585
    • Boiocchi, L.1    Mathew, S.2    Gianelli, U.3
  • 17
    • 81355148731 scopus 로고    scopus 로고
    • Identification of genomic aberrations associated with disease transformation by means of high-resolution SNP array analysis in patients with myeloproliferative neoplasm
    • E. Rumi, A. Harutyunyan, and C. Elena et al. Identification of genomic aberrations associated with disease transformation by means of high-resolution SNP array analysis in patients with myeloproliferative neoplasm Am J Hematol 86 2011 974 979
    • (2011) Am J Hematol , vol.86 , pp. 974-979
    • Rumi, E.1    Harutyunyan, A.2    Elena, C.3
  • 18
    • 77449126735 scopus 로고    scopus 로고
    • International Prognostic Scoring System - independent cytogenetic risk categorization in primary myelofibrosis
    • K. Hussein, A.D. Pardanani, and D.L. Van Dyke et al. International Prognostic Scoring System - independent cytogenetic risk categorization in primary myelofibrosis Blood 115 2010 496 499
    • (2010) Blood , vol.115 , pp. 496-499
    • Hussein, K.1    Pardanani, A.D.2    Van Dyke, D.L.3
  • 19
    • 79952087335 scopus 로고    scopus 로고
    • DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status
    • N. Gangat, D. Caramazza, and R. Vaidya et al. DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status J Clin Oncol 29 2011 392 397
    • (2011) J Clin Oncol , vol.29 , pp. 392-397
    • Gangat, N.1    Caramazza, D.2    Vaidya, R.3
  • 20
    • 63849328927 scopus 로고    scopus 로고
    • New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment
    • F. Cervantes, B. Dupriez, and A. Pereira et al. New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment Blood 113 2009 2895 2901
    • (2009) Blood , vol.113 , pp. 2895-2901
    • Cervantes, F.1    Dupriez, B.2    Pereira, A.3
  • 21
    • 77950352432 scopus 로고    scopus 로고
    • A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment)
    • F. Passamonti, F. Cervantes, and A.M. Vannucchi et al. A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment) Blood 115 2010 1703 1708
    • (2010) Blood , vol.115 , pp. 1703-1708
    • Passamonti, F.1    Cervantes, F.2    Vannucchi, A.M.3
  • 22
    • 84858830394 scopus 로고    scopus 로고
    • Leukemia risk models in primary myelofibrosis: an International Working Group study
    • A. Tefferi, A. Pardanani, and N. Gangat et al. Leukemia risk models in primary myelofibrosis: an International Working Group study Leukemia 26 2012 1439 1441
    • (2012) Leukemia , vol.26 , pp. 1439-1441
    • Tefferi, A.1    Pardanani, A.2    Gangat, N.3
  • 23
    • 84883742082 scopus 로고    scopus 로고
    • Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study
    • A. Tefferi, E. Rumi, and G. Finazzi et al. Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study Leukemia 27 2013 1874 1881
    • (2013) Leukemia , vol.27 , pp. 1874-1881
    • Tefferi, A.1    Rumi, E.2    Finazzi, G.3
  • 24
    • 84865187605 scopus 로고    scopus 로고
    • A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment
    • F. Passamonti, J. Thiele, and F. Girodon et al. A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment Blood 120 2012 1197 1201
    • (2012) Blood , vol.120 , pp. 1197-1201
    • Passamonti, F.1    Thiele, J.2    Girodon, F.3
  • 25
    • 80051803115 scopus 로고    scopus 로고
    • Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis: an international study
    • T. Barbui, J. Thiele, and F. Passamonti et al. Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis: an international study J Clin Oncol 29 2011 3179 3184
    • (2011) J Clin Oncol , vol.29 , pp. 3179-3184
    • Barbui, T.1    Thiele, J.2    Passamonti, F.3
  • 26
    • 79953711716 scopus 로고    scopus 로고
    • How I treat myelofibrosis
    • A. Tefferi How I treat myelofibrosis Blood 117 2011 3494 3504
    • (2011) Blood , vol.117 , pp. 3494-3504
    • Tefferi, A.1
  • 27
    • 39149105615 scopus 로고    scopus 로고
    • Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment
    • G. Barosi, R.A. Mesa, and J. Thiele et al. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment Leukemia 22 2008 437 438
    • (2008) Leukemia , vol.22 , pp. 437-438
    • Barosi, G.1    Mesa, R.A.2    Thiele, J.3
  • 28
    • 84890548359 scopus 로고    scopus 로고
    • WHO classification of myeloproliferative neoplasms (MPN): a critical update
    • H.M. Kvasnicka WHO classification of myeloproliferative neoplasms (MPN): a critical update Curr Hematol Malig Rep 8 2013 333 341
    • (2013) Curr Hematol Malig Rep , vol.8 , pp. 333-341
    • Kvasnicka, H.M.1
  • 29
    • 79957611312 scopus 로고    scopus 로고
    • Essential thrombocythemia versus early primary myelofibrosis: a multicenter study to validate the WHO classification
    • J. Thiele, H.M. Kvasnicka, and L. Mullauer et al. Essential thrombocythemia versus early primary myelofibrosis: a multicenter study to validate the WHO classification Blood 117 2011 5710 5718
    • (2011) Blood , vol.117 , pp. 5710-5718
    • Thiele, J.1    Kvasnicka, H.M.2    Mullauer, L.3
  • 30
    • 84881477148 scopus 로고    scopus 로고
    • Personalized management of essential thrombocythemia - application of recent evidence to clinical practice
    • A. Tefferi, and T. Barbui Personalized management of essential thrombocythemia - application of recent evidence to clinical practice Leukemia 27 2013 1617 1620
    • (2013) Leukemia , vol.27 , pp. 1617-1620
    • Tefferi, A.1    Barbui, T.2
  • 31
    • 84893964717 scopus 로고    scopus 로고
    • Masked polycythemia vera diagnosed according to WHO and BCSH classification
    • T. Barbui, J. Thiele, and A. Carobbio et al. Masked polycythemia vera diagnosed according to WHO and BCSH classification Am J Hematol 89 2014 199 202
    • (2014) Am J Hematol , vol.89 , pp. 199-202
    • Barbui, T.1    Thiele, J.2    Carobbio, A.3
  • 32
    • 84887373344 scopus 로고    scopus 로고
    • Evaluation of WHO criteria for diagnosis of polycythemia vera: a prospective analysis
    • R.T. Silver, W. Chow, and A. Orazi et al. Evaluation of WHO criteria for diagnosis of polycythemia vera: a prospective analysis Blood 122 2013 1881 1886
    • (2013) Blood , vol.122 , pp. 1881-1886
    • Silver, R.T.1    Chow, W.2    Orazi, A.3
  • 33
    • 84900852237 scopus 로고    scopus 로고
    • Discriminating between essential thrombocythemia and masked polycythemia vera in JAK2 mutated patients
    • T. Barbui, J. Thiele, and A. Carobbio et al. Discriminating between essential thrombocythemia and masked polycythemia vera in JAK2 mutated patients Am J Hematol 89 2014 588 590
    • (2014) Am J Hematol , vol.89 , pp. 588-590
    • Barbui, T.1    Thiele, J.2    Carobbio, A.3
  • 34
    • 84892882972 scopus 로고    scopus 로고
    • Masked polycythemia vera (mPV): results of an international study
    • T. Barbui, J. Thiele, and H. Gisslinger et al. Masked polycythemia vera (mPV): results of an international study Am J Hematol 89 2014 52 54
    • (2014) Am J Hematol , vol.89 , pp. 52-54
    • Barbui, T.1    Thiele, J.2    Gisslinger, H.3
  • 35
    • 84878999980 scopus 로고    scopus 로고
    • Myelofibrosis in Philadelphia chromosome-negative myeloproliferative neoplasms is associated with aberrant karyotypes
    • G. Hauck, D. Jonigk, and G. Göhring et al. Myelofibrosis in Philadelphia chromosome-negative myeloproliferative neoplasms is associated with aberrant karyotypes Cancer Genet 206 2013 116 123
    • (2013) Cancer Genet , vol.206 , pp. 116-123
    • Hauck, G.1    Jonigk, D.2    Göhring, G.3
  • 36
    • 84875279909 scopus 로고    scopus 로고
    • The role of cytokines in the initiation and progression of myelofibrosis
    • H.C. Hasselbalch The role of cytokines in the initiation and progression of myelofibrosis Cytokine Growth Factor Rev 24 2013 133 145
    • (2013) Cytokine Growth Factor Rev , vol.24 , pp. 133-145
    • Hasselbalch, H.C.1
  • 37
    • 84875245207 scopus 로고    scopus 로고
    • Primary myelofibrosis and the "bad seeds in bad soil" concept
    • M.C. Le Bousse-Kerdilès Primary myelofibrosis and the "bad seeds in bad soil" concept Fibrogenesis Tissue Repair 5 suppl 1 2012 S20
    • (2012) Fibrogenesis Tissue Repair , vol.5 , pp. S20
    • Le Bousse-Kerdilès, M.C.1
  • 38
    • 55749093276 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms underlying bone marrow and liver fibrosis: a review
    • M.C. Le Bousse-Kerdilès, M.C. Martyré, and M. Samson Cellular and molecular mechanisms underlying bone marrow and liver fibrosis: a review Eur Cytokine Netw 19 2008 69 80
    • (2008) Eur Cytokine Netw , vol.19 , pp. 69-80
    • Le Bousse-Kerdilès, M.C.1    Martyré, M.C.2    Samson, M.3
  • 41
    • 79954625832 scopus 로고    scopus 로고
    • Bone marrow fibrosis in myeloproliferative neoplasms-associated myelofibrosis: deconstructing a myth?
    • G. Barosi, and R.P. Gale Bone marrow fibrosis in myeloproliferative neoplasms-associated myelofibrosis: deconstructing a myth? Leuk Res 35 2011 563 565
    • (2011) Leuk Res , vol.35 , pp. 563-565
    • Barosi, G.1    Gale, R.P.2
  • 42
    • 79960943078 scopus 로고    scopus 로고
    • Laser-capture microdissection and analysis of liver endothelial cells from patients with Budd-Chiari syndrome
    • S. Sozer, and R. Hoffman Laser-capture microdissection and analysis of liver endothelial cells from patients with Budd-Chiari syndrome Methods Mol Biol 755 2011 405 415
    • (2011) Methods Mol Biol , vol.755 , pp. 405-415
    • Sozer, S.1    Hoffman, R.2
  • 43
    • 84865725060 scopus 로고    scopus 로고
    • Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection
    • N. Papadantonakis, S. Matsuura, and K. Ravid Megakaryocyte pathology and bone marrow fibrosis: the lysyl oxidase connection Blood 120 2012 1774 1781
    • (2012) Blood , vol.120 , pp. 1774-1781
    • Papadantonakis, N.1    Matsuura, S.2    Ravid, K.3
  • 44
    • 0037409903 scopus 로고    scopus 로고
    • Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: a follow-up study on 309 patients
    • J. Thiele, H.M. Kvasnicka, A. Schmitt-Graeff, and V. Diehl Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: a follow-up study on 309 patients Leuk Lymphoma 44 2003 949 953
    • (2003) Leuk Lymphoma , vol.44 , pp. 949-953
    • Thiele, J.1    Kvasnicka, H.M.2    Schmitt-Graeff, A.3    Diehl, V.4
  • 45
    • 24944524079 scopus 로고    scopus 로고
    • European consensus on grading bone marrow fibrosis and assessment of cellularity
    • J. Thiele, H.M. Kvasnicka, and F. Facchetti et al. European consensus on grading bone marrow fibrosis and assessment of cellularity Haematologica 90 2005 1128 1132
    • (2005) Haematologica , vol.90 , pp. 1128-1132
    • Thiele, J.1    Kvasnicka, H.M.2    Facchetti, F.3
  • 46
    • 84926143782 scopus 로고    scopus 로고
    • High concordance in grading reticulin fibrosis and cellularity in patients with myeloproliferative neoplasms
    • O. Pozdnyakova, K. Wu, and A. Patki et al. High concordance in grading reticulin fibrosis and cellularity in patients with myeloproliferative neoplasms Mod Pathol 27 2014 1447 1454
    • (2014) Mod Pathol , vol.27 , pp. 1447-1454
    • Pozdnyakova, O.1    Wu, K.2    Patki, A.3
  • 47
    • 84928280304 scopus 로고    scopus 로고
    • Criteria for therapy response and progression in patients with myelofibrosis based on bone marrow features [abstract 1410]
    • Paper presented at: March 1-7, 2014; San Diego, Calif
    • Kvasnicka HM, Thiele J, Orazi A, et al. Criteria for therapy response and progression in patients with myelofibrosis based on bone marrow features [abstract 1410]. Paper presented at: 103rd USCAP Annual Meeting; March 1-7, 2014; San Diego, Calif.
    • 103rd USCAP Annual Meeting
    • Kvasnicka, H.M.1    Thiele, J.2    Orazi A3
  • 48
    • 84865714762 scopus 로고    scopus 로고
    • The European Consensus on grading of bone marrow fibrosis allows a better prognostication of patients with primary myelofibrosis
    • U. Gianelli, C. Vener, and A. Bossi et al. The European Consensus on grading of bone marrow fibrosis allows a better prognostication of patients with primary myelofibrosis Mod Pathol 25 2012 1193 1202
    • (2012) Mod Pathol , vol.25 , pp. 1193-1202
    • Gianelli, U.1    Vener, C.2    Bossi, A.3
  • 49
    • 84893190328 scopus 로고    scopus 로고
    • Contribution of comorbidities and grade of bone marrow fibrosis to the prognosis of survival in patients with primary myelofibrosis
    • D. Lekovic, M. Gotic, and M. Perunicic-Jovanovic et al. Contribution of comorbidities and grade of bone marrow fibrosis to the prognosis of survival in patients with primary myelofibrosis Med Oncol 31 2014 869
    • (2014) Med Oncol , vol.31 , pp. 869
    • Lekovic, D.1    Gotic, M.2    Perunicic-Jovanovic, M.3
  • 50
    • 84885600843 scopus 로고    scopus 로고
    • Prognostic implications and clinical characteristics associated with bone marrow fibrosis in patients with myelofibrosis
    • A. Nazha, Z. Estrov, and J. Cortes et al. Prognostic implications and clinical characteristics associated with bone marrow fibrosis in patients with myelofibrosis Leuk Lymphoma 54 2013 2537 2539
    • (2013) Leuk Lymphoma , vol.54 , pp. 2537-2539
    • Nazha, A.1    Estrov, Z.2    Cortes, J.3
  • 51
    • 67649933816 scopus 로고    scopus 로고
    • Reticulin accumulation in essential thrombocythemia: prognostic significance and relationship to therapy
    • P.J. Campbell, D. Bareford, and W.N. Erber et al. Reticulin accumulation in essential thrombocythemia: prognostic significance and relationship to therapy J Clin Oncol 27 2009 2991 2999
    • (2009) J Clin Oncol , vol.27 , pp. 2991-2999
    • Campbell, P.J.1    Bareford, D.2    Erber, W.N.3
  • 52
    • 84858062280 scopus 로고    scopus 로고
    • Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome
    • T. Barbui, J. Thiele, and F. Passamonti et al. Initial bone marrow reticulin fibrosis in polycythemia vera exerts an impact on clinical outcome Blood 119 2012 2239 2241
    • (2012) Blood , vol.119 , pp. 2239-2241
    • Barbui, T.1    Thiele, J.2    Passamonti, F.3
  • 53
    • 84885613109 scopus 로고    scopus 로고
    • Replacement of hematopoietic system by allogeneic stem cell transplantation in myelofibrosis patients induces rapid regression of bone marrow fibrosis
    • N. Kröger, M. Kvasnicka, and J. Thiele Replacement of hematopoietic system by allogeneic stem cell transplantation in myelofibrosis patients induces rapid regression of bone marrow fibrosis Fibrogenesis Tissue Repair 5 suppl 1 2012 S25
    • (2012) Fibrogenesis Tissue Repair , vol.5 , pp. S25
    • Kröger, N.1    Kvasnicka, M.2    Thiele, J.3
  • 54
    • 35448930206 scopus 로고    scopus 로고
    • Rapid regression of bone marrow fibrosis after dose-reduced allogeneic stem cell transplantation in patients with primary myelofibrosis
    • N. Kröger, J. Thiele, and A. Zander et al. Rapid regression of bone marrow fibrosis after dose-reduced allogeneic stem cell transplantation in patients with primary myelofibrosis Exp Hematol 35 2007 1719 1722
    • (2007) Exp Hematol , vol.35 , pp. 1719-1722
    • Kröger, N.1    Thiele, J.2    Zander, A.3
  • 55
    • 84899943540 scopus 로고    scopus 로고
    • Dynamic of bone marrow fibrosis regression predicts survival after allogeneic stem cell transplantation for myelofibrosis
    • N. Kröger, T. Zabelina, and H. Alchalby et al. Dynamic of bone marrow fibrosis regression predicts survival after allogeneic stem cell transplantation for myelofibrosis Biol Blood Marrow Transplant 20 2014 812 815
    • (2014) Biol Blood Marrow Transplant , vol.20 , pp. 812-815
    • Kröger, N.1    Zabelina, T.2    Alchalby, H.3
  • 56
    • 34548756046 scopus 로고    scopus 로고
    • Progression of bone marrow fibrosis in patients with essential thrombocythemia and polycythemia vera during anagrelide treatment
    • M. Hultdin, G. Sundström, and A. Wahlin et al. Progression of bone marrow fibrosis in patients with essential thrombocythemia and polycythemia vera during anagrelide treatment Med Oncol 24 2007 63 70
    • (2007) Med Oncol , vol.24 , pp. 63-70
    • Hultdin, M.1    Sundström, G.2    Wahlin, A.3
  • 57
    • 71049138895 scopus 로고    scopus 로고
    • Minimal residual disease and normalization of the bone marrow after long-term treatment with alpha-interferon2b in polycythemia vera. A report on molecular response patterns in seven patients in sustained complete hematological remission
    • T. Stauffer Larsen, M.B. Møller, and K. de Stricker et al. Minimal residual disease and normalization of the bone marrow after long-term treatment with alpha-interferon2b in polycythemia vera. A report on molecular response patterns in seven patients in sustained complete hematological remission Hematology 14 2009 331 334
    • (2009) Hematology , vol.14 , pp. 331-334
    • Stauffer Larsen, T.1    Møller, M.B.2    De Stricker, K.3
  • 58
    • 0032412348 scopus 로고    scopus 로고
    • Reversal of bone marrow fibrosis in idiopathic myelofibrosis after treatment with alpha-interferon
    • M.A. Domingues, A.T. Haepers, and I.H. Massaut et al. Reversal of bone marrow fibrosis in idiopathic myelofibrosis after treatment with alpha-interferon Haematologica 83 1998 1124 1125
    • (1998) Haematologica , vol.83 , pp. 1124-1125
    • Domingues, M.A.1    Haepers, A.T.2    Massaut, I.H.3
  • 59
    • 67651000081 scopus 로고    scopus 로고
    • Recombinant interferon alpha (rIFNα-2b) may retard progression of early primary myelofibrosis
    • R.T. Silver, and K. Vandris Recombinant interferon alpha (rIFNα-2b) may retard progression of early primary myelofibrosis Leukemia 23 2009 1366 1369
    • (2009) Leukemia , vol.23 , pp. 1366-1369
    • Silver, R.T.1    Vandris, K.2
  • 60
    • 79959232873 scopus 로고    scopus 로고
    • Recombinant interferon-α may retard progression of early primary myelofibrosis: a preliminary report
    • R.T. Silver, K. Vandris, and J.J. Goldman Recombinant interferon-α may retard progression of early primary myelofibrosis: a preliminary report Blood 117 2011 6669 6672
    • (2011) Blood , vol.117 , pp. 6669-6672
    • Silver, R.T.1    Vandris, K.2    Goldman, J.J.3
  • 61
    • 84928280303 scopus 로고    scopus 로고
    • Recombinant interferon alpha therapy decreases bone marrow fibrosis and cellularity and improves megakaryocyte morphology in a significant portion of patients with myelofibrosis [abstract 1597]
    • Paper presented at: March 1-7, 2014; San Diego, Calif.
    • Zhou J, Gong P, Silver RT, et al. Recombinant interferon alpha therapy decreases bone marrow fibrosis and cellularity and improves megakaryocyte morphology in a significant portion of patients with myelofibrosis [abstract 1597]. Paper presented at: 103rd USCAP Annual Meeting; March 1-7, 2014; San Diego, Calif.
    • 103rd USCAP Annual Meeting
    • Zhou, J.1    Gong, P.2    Silver, R.T.3
  • 62
    • 38449097977 scopus 로고    scopus 로고
    • Mini-dose of thalidomide for treatment of primary myelofibrosis. Report of a case with complete reversal of bone marrow fibrosis and splenomegaly
    • A. Berrebi, E. Feldberg, I. Spivak, and L. Shvidel Mini-dose of thalidomide for treatment of primary myelofibrosis. Report of a case with complete reversal of bone marrow fibrosis and splenomegaly Haematologica 92 2007 e15 e16
    • (2007) Haematologica , vol.92 , pp. e15-e16
    • Berrebi, A.1    Feldberg, E.2    Spivak, I.3    Shvidel, L.4
  • 63
    • 70350439432 scopus 로고    scopus 로고
    • Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis
    • A. Quintás-Cardama, H.M. Kantarjian, and T. Manshouri et al. Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis J Clin Oncol 27 2009 4760 4766
    • (2009) J Clin Oncol , vol.27 , pp. 4760-4766
    • Quintás-Cardama, A.1    Kantarjian, H.M.2    Manshouri, T.3
  • 64
    • 84863393110 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
    • S. Verstovsek, R.A. Mesa, and J. Gotlib et al. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis N Engl J Med 366 2012 799 807
    • (2012) N Engl J Med , vol.366 , pp. 799-807
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 65
    • 84857837774 scopus 로고    scopus 로고
    • JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
    • C. Harrison, J.J. Kiladjian, and H.K. Al-Ali et al. JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis N Engl J Med 366 2012 787 798
    • (2012) N Engl J Med , vol.366 , pp. 787-798
    • Harrison, C.1    Kiladjian, J.J.2    Al-Ali, H.K.3
  • 66
    • 84876790720 scopus 로고    scopus 로고
    • The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis
    • S. Verstovsek, R.A. Mesa, and J. Gotlib et al. The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis Br J Haematol 161 2013 508 516
    • (2013) Br J Haematol , vol.161 , pp. 508-516
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 67
    • 84901007488 scopus 로고    scopus 로고
    • Long-term outcomes of ruxolitinib therapy in patients with myelofibrosis: 3-year update from COMFORT-I [abstract]
    • S. Verstovsek, R.A. Mesa, and J. Gotlib et al. Long-term outcomes of ruxolitinib therapy in patients with myelofibrosis: 3-year update from COMFORT-I [abstract] Blood 122 2013 396
    • (2013) Blood , vol.122 , pp. 396
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 68
    • 84887014885 scopus 로고    scopus 로고
    • Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I
    • S. Verstovsek, R.A. Mesa, and J. Gotlib et al. Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I Haematologica 98 2013 1865 1871
    • (2013) Haematologica , vol.98 , pp. 1865-1871
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 69
    • 84891303523 scopus 로고    scopus 로고
    • Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis
    • F. Cervantes, A.M. Vannucchi, and J.J. Kiladjian et al. Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis Blood 122 2013 4047 4053
    • (2013) Blood , vol.122 , pp. 4047-4053
    • Cervantes, F.1    Vannucchi, A.M.2    Kiladjian, J.J.3
  • 70
    • 84897528714 scopus 로고    scopus 로고
    • Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts
    • F. Passamonti, M. Maffioli, and F. Cervantes et al. Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts Blood 123 2014 1833 1855
    • (2014) Blood , vol.123 , pp. 1833-1855
    • Passamonti, F.1    Maffioli, M.2    Cervantes, F.3
  • 71
    • 84889852354 scopus 로고    scopus 로고
    • Resolution of bone marrow fibrosis in a patient receiving JAK1/JAK2 inhibitor treatment with ruxolitinib
    • B.S. Wilkins, D. Radia, and C. Woodley et al. Resolution of bone marrow fibrosis in a patient receiving JAK1/JAK2 inhibitor treatment with ruxolitinib Haematologica 98 2013 1872 1876
    • (2013) Haematologica , vol.98 , pp. 1872-1876
    • Wilkins, B.S.1    Radia, D.2    Woodley, C.3
  • 72
    • 84921728761 scopus 로고    scopus 로고
    • Disappearance of fibrosis in secondary myelofibrosis after ruxolitinib treatment: new endpoint to achieve?
    • M. Molica, A. Serrao, and R. Saracino et al. Disappearance of fibrosis in secondary myelofibrosis after ruxolitinib treatment: new endpoint to achieve? Ann Hematol 93 2014 1951 1952
    • (2014) Ann Hematol , vol.93 , pp. 1951-1952
    • Molica, M.1    Serrao, A.2    Saracino, R.3
  • 73
    • 77956696835 scopus 로고    scopus 로고
    • Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis
    • S. Verstovsek, H. Kantarjian, and R.A. Mesa et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis N Engl J Med 363 2010 1117 1127
    • (2010) N Engl J Med , vol.363 , pp. 1117-1127
    • Verstovsek, S.1    Kantarjian, H.2    Mesa, R.A.3
  • 74
    • 84882803340 scopus 로고    scopus 로고
    • Exploratory analysis of the effect of ruxolitinib on bone marrow morphology in patients with myelofibrosis [abstract 7030]
    • H.M. Kvasnicka, J. Thiele, and C.E. Bueso-Ramos et al. Exploratory analysis of the effect of ruxolitinib on bone marrow morphology in patients with myelofibrosis [abstract 7030] J Clin Oncol 31 suppl 2013
    • (2013) J Clin Oncol , vol.31
    • Kvasnicka, H.M.1    Thiele, J.2    Bueso-Ramos, C.E.3
  • 75
    • 84897566182 scopus 로고    scopus 로고
    • Effects of five-years of ruxolitinib therapy on bone marrow morphology in patients with myelofibrosis and comparison with best available therapy [abstract]
    • H.M. Kvasnicka, J. Thiele, and C.E. Bueso-Ramos et al. Effects of five-years of ruxolitinib therapy on bone marrow morphology in patients with myelofibrosis and comparison with best available therapy [abstract] Blood 122 2013 4055
    • (2013) Blood , vol.122 , pp. 4055
    • Kvasnicka, H.M.1    Thiele, J.2    Bueso-Ramos, C.E.3
  • 76
    • 84897566182 scopus 로고    scopus 로고
    • Effects of ruxolitinib therapy on megakaryocyte morphology and inflammatory bone marrow reaction in patients with myelofibrosis [abstract]
    • H.M. Kvasnicka, J. Thiele, and C.E. Bueso-Ramos et al. Effects of ruxolitinib therapy on megakaryocyte morphology and inflammatory bone marrow reaction in patients with myelofibrosis [abstract] Blood 122 2013 4056
    • (2013) Blood , vol.122 , pp. 4056
    • Kvasnicka, H.M.1    Thiele, J.2    Bueso-Ramos, C.E.3
  • 77
    • 84901033447 scopus 로고    scopus 로고
    • Effect of treatment with the JAK2-selective inhibitor fedratinib (SAR302503) on bone marrow histology in patients with myeloproliferative neoplasms with myelofibrosis [abstract]
    • C.H.M. Jamieson, R.P. Hasserjian, and J. Gotlib et al. Effect of treatment with the JAK2-selective inhibitor fedratinib (SAR302503) on bone marrow histology in patients with myeloproliferative neoplasms with myelofibrosis [abstract] Blood 122 2013 2823
    • (2013) Blood , vol.122 , pp. 2823
    • Jamieson, C.H.M.1    Hasserjian, R.P.2    Gotlib, J.3
  • 78
    • 84858843560 scopus 로고    scopus 로고
    • Phase I study of the JAK2 V617F inhibitor, LY2784544, in patients with myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET) [abstract]
    • S. Verstovsek, R.A. Mesa, and S.K. Rhoades et al. Phase I study of the JAK2 V617F inhibitor, LY2784544, in patients with myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET) [abstract] Blood 118 2011 2814
    • (2011) Blood , vol.118 , pp. 2814
    • Verstovsek, S.1    Mesa, R.A.2    Rhoades, S.K.3
  • 79
    • 84875032119 scopus 로고    scopus 로고
    • A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF)
    • J. Mascarenhas, M. Lu, and T. Li et al. A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF) Br J Haematol 161 2013 68 75
    • (2013) Br J Haematol , vol.161 , pp. 68-75
    • Mascarenhas, J.1    Lu, M.2    Li, T.3
  • 80
    • 84897000773 scopus 로고    scopus 로고
    • Imetelstat, a telomerase inhibitor, induces morphologic and molecular remissions in myelofibrosis and reversal of bone marrow fibrosis [abstract]
    • A. Tefferi, K. Begna, and R.R. Laborde et al. Imetelstat, a telomerase inhibitor, induces morphologic and molecular remissions in myelofibrosis and reversal of bone marrow fibrosis [abstract] Blood 122 2013 662
    • (2013) Blood , vol.122 , pp. 662
    • Tefferi, A.1    Begna, K.2    Laborde, R.R.3
  • 81
    • 84865272337 scopus 로고    scopus 로고
    • The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis
    • A. Kirabo, S.O. Park, and H.L. Wamsley et al. The small molecule inhibitor G6 significantly reduces bone marrow fibrosis and the mutant burden in a mouse model of Jak2-mediated myelofibrosis Am J Pathol 181 2012 858 865
    • (2012) Am J Pathol , vol.181 , pp. 858-865
    • Kirabo, A.1    Park, S.O.2    Wamsley, H.L.3
  • 82
    • 84928283407 scopus 로고    scopus 로고
    • Phase 2 trial of PRM-151, an antifibrotic agent, in patients with myelofibrois: stage 1 results [abstract 7114]
    • S. Verstovsek, R.A. Mesa, and L.M. Foltz et al. Phase 2 trial of PRM-151, an antifibrotic agent, in patients with myelofibrois: stage 1 results [abstract 7114] J Clin Oncol 32 suppl 2014
    • (2014) J Clin Oncol , vol.32
    • Verstovsek, S.1    Mesa, R.A.2    Foltz, L.M.3
  • 83
    • 0018675904 scopus 로고
    • The reticulin content of bone marrow in acute leukaemia in adults
    • A. Manoharan, R. Horsley, and W.R. Pitney The reticulin content of bone marrow in acute leukaemia in adults Br J Haematol 43 1979 185 190
    • (1979) Br J Haematol , vol.43 , pp. 185-190
    • Manoharan, A.1    Horsley, R.2    Pitney, W.R.3


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