STC1 expression is associated with tumor growth and metastasis in breast cancer

Clinical and Experimental Metastasis

Volumn 32, Issue 1, 2015, Pages 15-27

  Chang, Andy C M ^a,b   Doherty, Judy ^c   Huschtscha, Lily I ^a,b   Redvers, Richard ^c   Restall, Christina ^c   Reddel, Roger R ^a,b   Anderson, Robin L ^c,d  

^a CHILDREN'S MEDICAL RESEARCH INSTITUTE   (Australia)

^b University of Sydney   (Australia)

^c PETER MACCALLUM CANCER CENTRE   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Breast cancer; Metastasis; Stanniocalcin 1; STC1; Tumor growth

Indexed keywords

COMPLEMENTARY DNA; HYPOCALCIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; RNA; SHORT HAIRPIN RNA; STANNIOCALCIN 1; STROMELYSIN; UNCLASSIFIED DRUG; GLYCOPROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BREAST CANCER; BREAST CANCER CELL LINE; BREAST TUMOR; CANCER GROWTH; CANCER PROGNOSIS; CELL CLONE; CELL INVASION; CELL INVASION ASSAY; CELL PROLIFERATION; CELL PROLIFERATION ASSAY; COMPARATIVE STUDY; CONTROLLED STUDY; DIAPHRAGM METASTASIS; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; DNA SYNTHESIS; DOWN REGULATION; EX VIVO STUDY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GROWTH RATE; HEART METASTASIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; LYMPH NODE METASTASIS; METASTASIS; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; PRIMARY TUMOR; PROTEIN EXPRESSION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBCAGE METASTASIS; RNA ISOLATION; TUMOR MODEL; UPREGULATION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BONE TUMOR; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; LUNG TUMOR; PATHOLOGY; RNA INTERFERENCE; SCID MOUSE; SECONDARY; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; BONE NEOPLASMS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOPROTEINS; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MICE; MICE, INBRED BALB C; MICE, SCID; NEOPLASM INVASIVENESS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84928268844     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-014-9687-9     Document Type: Article

References (56)

1. Eckhardt BL, Francis PA, Parker BS et al (2012) Strategies for the discovery and development of therapies for metastatic breast cancer. Nat Rev Drug Discov 11:479–497
2. Chang AC, Jellinek DA, Reddel RR (2003) Mammalian stanniocalcins and cancer. Endocr Relat Cancer 10:359–373
3. Yeung BH, Law AY, Wong CK (2012) Evolution and roles of stanniocalcin. Mol Cell Endocrinol 349:272–280
4. Roch GJ, Sherwood NM (2011) Stanniocalcin has deep evolutionary roots in eukaryotes. Genome Biol Evol 3:284–294
5. Wagner GF, Fenwick JC, Park CM et al (1988) Comparative biochemistry and physiology of teleocalcin from sockeye and coho salmon. Gen Comp Endocrinol 72:237–246
6. Sundell K, Bjornsson BT, Itoh H et al (1992) Chum salmon (Oncorhynchus keta) stanniocalcin inhibits in vitro calcium uptake in Atlantic cod (Gadus morhua). J Comp Physiol B 162:489–495
7. Nguyen A, Chang AC, Reddel RR (2009) Stanniocalcin-1 acts in a negative feedback loop in the prosurvival ERK1/2 signaling pathway during oxidative stress. Oncogene 28:1982–1992
8. Zhang K, Lindsberg PJ, Tatlisumak T et al (2000) Stanniocalcin: a molecular guard of neurons during cerebral ischemia. Proc Natl Acad Sci USA 97:3637–3642
9. Roddy GW, Rosa RH Jr, Youn OhJ et al (2012) Stanniocalcin-1 rescued photoreceptor degeneration in two rat models of inherited retinal degeneration. Mol Ther 20:788–797
10. Kanellis J, Bick R, Garcia G et al (2004) Stanniocalcin-1, an inhibitor of macrophage chemotaxis and chemokinesis. Am J Physiol Renal Physiol 286:F356–F362
11. Liu G, Yang G, Chang B et al (2010) Stanniocalcin 1 and ovarian tumorigenesis. J Natl Cancer Inst 102:812–827
12. Welcsh PL, Lee MK, Gonzalez-Hernandez RM et al (2002) BRCA1 transcriptionally regulates genes involved in breast tumorigenesis. Proc Natl Acad Sci U S A 99:7560–7565
13. Charpentier AH, Bednarek AK, Daniel RL et al (2000) Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Res 60:5977–5983
14. Bouras T, Southey MC, Chang AC et al (2002) Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer. Cancer Res 62:1289–1295
15. Raulic S, Ramos-Valdes Y, Dimattia GE (2008) Stanniocalcin 2 expression is regulated by hormone signalling and negatively affects breast cancer cell viability in vitro. J Endocrinol 197:517–529
16. Eckhardt BL, Parker BS, van Laar RK et al (2005) Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix. Mol Cancer Res 3:1–13
17. Chang XZ, Li DQ, Hou YF et al (2007) Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer. Br Cancer Res 9:R76
18. Sloan EK, Pouliot N, Stanley KL et al (2006) Tumor-specific expression of αvβ3 integrin promotes spontaneous metastasis of breast cancer to bone. Breast Cancer Res 8:R20
19. Aslakson CJ, Miller FR (1992) Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor. Cancer Res 52:1399–1405
20. Lelekakis M, Moseley JM, Martin TJ et al (1999) A novel orthotopic model of breast cancer metastasis to bone. Clin Exp Metastasis 17:163–170
21. Jellinek DA, Chang AC, Larsen MR et al (2000) Stanniocalcin 1 and 2 are secreted as phosphoproteins from human fibrosarcoma cells. Biochem J 350:453–461
22. Kao J, Salari K, Bocanegra M et al (2009) Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery. PLoS One 4:e6146
23. Guo F, Li Y, Wang J et al (2013) Stanniocalcin1 (STC1) inhibits cell proliferation and invasion of cervical cancer cells. PLoS One 8:e53989
24. Sheikh-Hamad D (2010) Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol 298:F248–F254
25. Murai R, Tanaka M, Takahashi Y et al (2014) Stanniocalcin-1 promotes metastasis in a human breast cancer cell line through activation of PI3K. Clin Exp Metastasis 31:787
26. Daniel AR, Lange CA (2009) Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells. Proc Natl Acad Sci USA 106:14287–14292
27. Pena C, Cespedes MV, Bradic Lindh M et al (2013) STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer. Cancer Res 73:1287–1297
28. Fujiwara Y, Sugita Y, Nakamori S et al (2000) Assessment of stanniocalcin-1 mRNA as a molecular marker for micrometastases of various human cancers. Int J Oncol 16:799–804
29. Tohmiya Y, Koide Y, Fujimaki S et al (2004) Stanniocalcin-1 as a novel marker to detect minimal residual disease of human leukemia. Tohoku J Exp Med 204:125–133
30. Wascher RA, Huynh KT, Giuliano AE et al (2003) Stanniocalcin-1: a novel molecular blood and bone marrow marker for human breast cancer. Clin Cancer Res 9:1427–1435
31. Nakagawa T, Martinez SR, Goto Y et al (2007) Detection of circulating tumor cells in early-stage breast cancer metastasis to axillary lymph nodes. Clin Cancer Res 13:4105–4110
32. Liao D, Corle C, Seagroves TN et al (2007) Hypoxia-inducible factor-1α is a key regulator of metastasis in a transgenic model of cancer initiation and progression. Cancer Res 67:563–572
33. Yeung HY, Lai KP, Chan HY et al (2005) Hypoxia-inducible factor-1-mediated activation of stanniocalcin-1 in human cancer cells. Endocrinology 146:4951–4960
34. Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674
35. Azalea-Romero M, Gonzalez-Mendoza M, Caceres-Perez AA et al (2012) Low expression of stem cell antigen-1 on mouse haematopoietic precursors is associated with erythroid differentiation. Cell Immunol 279:187–195
36. Labarge MA (2013) Breaking the canon: indirect regulation of Wnt signaling in mammary stem cells by MMP3. Cell Stem Cell 13:259–260
37. Xiong J, Du Q, Liang Z (2010) Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein. Oncogene 29:4980–4988
38. Sribenja S, Wongkham S, Wongkham C et al (2013) Roles and mechanisms of β-thymosins in cell migration and cancer metastasis: an update. Cancer Invest 31:103–110
39. Britschgi A, Radimerski T, Bentires-Alj M (2013) Targeting PI3K, HER2 and the IL-8/JAK2 axis in metastatic breast cancer: which combination makes the whole greater than the sum of its parts? Drug Resist Updat 16:68–72
40. Papadopoulos MC, Saadoun S, Verkman AS (2008) Aquaporins and cell migration. Pflugers Arch 456:693–700
41. Dumitru CA, Bankfalvi A, Gu X et al (2013) AHNAK and inflammatory markers predict poor survival in laryngeal carcinoma. PLoS One 8:e56420
42. Maeda M, Hasegawa H, Hyodo T et al (2011) ARHGAP18, a GTPase-activating protein for RhoA, controls cell shape, spreading, and motility. Mol Biol Cell 22:3840–3852
43. Goebel G, Berger R, Strasak AM et al (2012) Elevated mRNA expression of CHAC1 splicing variants is associated with poor outcome for breast and ovarian cancer patients. Br J Cancer 106:189–198
44. Korpal M, Ell BJ, Buffa FM et al (2011) Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med 17:1101–1108
45. Yang WC, Tsai WC, Lin PM et al (2013) Human BDH2, an anti-apoptosis factor, is a novel poor prognostic factor for de novo cytogenetically normal acute myeloid leukemia. J Biomed Sci 20:58
46. Godoy P, Cadenas C, Hellwig B et al (2014) Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response. Breast Cancer 21:491–499
47. Schreiber R, Uliyakina I, Kongsuphol P et al (2010) Expression and function of epithelial anoctamins. J Biol Chem 285:7838–7845
48. Tani K, Fujiyoshi Y (2014) Water channel structures analysed by electron crystallography. Biochim Biophys Acta 1840:1605–1613
49. Suzuki T, Toyohara T, Akiyama Y et al (2011) Transcriptional regulation of organic anion transporting polypeptide SLCO4C1 as a new therapeutic modality to prevent chronic kidney disease. J Pharm Sci 100:3696–3707
50. Kottgen A, Glazer NL, Dehghan A et al (2009) Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet 41:712–717
51. Koizumi K, Hoshiai M, Ishida H et al (2007) Stanniocalcin 1 prevents cytosolic Ca(2+) overload and cell hypercontracture in cardiomyocytes. Circ J 71:796–801
52. Durukan Tolvanen A, Westberg JA, Serlachius M et al (2013) Stanniocalcin 1 is important for poststroke functionality, but dispensable for ischemic tolerance. Neuroscience 229:49–54
53. Yoneda T, Tanaka S, Hata K (2013) Role of RANKL/RANK in primary and secondary breast cancer. World J Orthop 4:178–185
54. Chang AC, Janosi J, Hulsbeek M et al (1995) A novel human cDNA highly homologous to the fish hormone stanniocalcin. Mol Cell Endocrinol 112:241–247
55. Saidak Z, Boudot C, Abdoune R et al (2009) Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor. Exp Cell Res 315:2072–2080
56. Rhodes DR, Yu J, Shanker K et al (2004) ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 6:1–6