Stanniocalcin 2 expression is regulated by hormone signalling and negatively affects breast cancer cell viability in vitro

Journal of Endocrinology

Volumn 197, Issue 3, 2008, Pages 517-529

  Raulic, Sanda ^a,b   Ramos Valdes, Yudith ^a   DiMattia, Gabriel E ^a,b  

^a LONDON REGIONAL CANCER PROGRAM   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; GLYCOPROTEIN; HYPOCALCIN; PROGESTERONE; PROGESTERONE RECEPTOR; RETINOIC ACID; STANNIOCALCIN 1; STANNIOCALCIN 2;

ANIMAL TISSUE; ARTICLE; AUTOCRINE EFFECT; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; ENDOMETRIUM CANCER; GENETIC TRANSCRIPTION; HORMONAL REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; ESTRADIOL; FEMALE; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; SIGNAL TRANSDUCTION; TRETINOIN;

EID: 44949246247     PISSN: 00220795     EISSN: 14796805     Source Type: Journal    
DOI: 10.1677/JOE-08-0043     Document Type: Article

References (65)

1. Amatschek S, Koenig U, Auer H, Steinlein P, Pacher M, Gruenfelder A, Dekan G, Vogl S, Kubista E, Heider KH et al. 2004 Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes. Cancer Research 64 844-856.
2. Anderson HC 2003 Matrix vesicles and calcification. Current Rheumatology Reports 5 222-226.
3. Andreu P, Colnot S, Godard C, Laurent-Puig P, Lamarque D, Kahn A, Perret C & Romagnolo B 2006 Identification of the IFITM family as a new molecular marker in human colorectal tumors. Cancer Research 66 1949-1955.
4. Bouras T, Southey MC, Chang AC, Reddel RR, Willhite D, Glynne R, Henderson MA, Armes JE & Venter DJ 2002 Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer. Cancer Research 62 1289-1295.
5. Bradford MM 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 248-254.
6. Brahimi-Horn MC & Pouyssegur J 2007 Hypoxia in cancer cell metabolism and pH regulation. Essays in Biochemistry 43 165-178.
7. Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF et al. 2006 Genome-wide analysis of estrogen receptor binding sites. Nature Genetics 38 1289-1297.
8. Chambhss KL & Shaul PW 2002 Estrogen modulation of endothelial nitric oxide synthase. Endocrine Reviews 23 665-686.
9. Chang AC & Reddel RR 1998 Identification of 2 second stanniocalcin cDNA in mouse and human: stanniocalcin 2. Molecular and Cellular Endocrinology 141 95-99.
10. Chang AC, Jellinek DA & Reddel RR 2003 Mammalian stanniocalcins and cancer. Endocrine-Related Cancer 10 359-373.
11. Chang AC, Cha J, Koentgen F & Reddel RR 2005 The murine stanniocalcin 1 gene is not essential for growth and development. Molecular and Cellular Biology 25 10604-10610.
12. Charpentier AH, Bednarek AK, Daniel RL, Hawkins KA, Laflin KJ, Gaddis S, MacLeod MC & Aldaz CM 2000 Effects of estrogen on global gene expression: identification of novel targets of estrogen action. Cancer Research 60 5977-5983.
13. Dauvois S, Danielian PS, White R & Parker MG 1992 Antiestrogen ICI 164,384 reduces cellular estrogen receptor content by increasing its turnover. PNAS 89 4037-4041.
14. Dean DM & Sanders MM 1996 Ten years after: reclassification of steroid-responsive genes. Molecular Endocrinology 10 1489-1495.
15. Deol HK, Varghese R, Wagner GF & DiMattia GE 2000 Dynamic regulation of mouse ovarian stanniocalcin expression during gestation and lactation. Endocrinology 141 3412-3421.
16. DiMattia GE, Varghese R & Wagner GF 1998 Molecular cloning and characterization of stanniocalcin-related protein. Molecular and Cellular Endocrinology 146 137-140.
17. Esseghir S, Reis-Filho JS, Kennedy A, James M, O'Hare MJ, Jeffery R, Poulsom R & Isacke CM 2006 Identification of transmembrane proteins as potential prognostic markers and therapeutic targets in breast cancer by a screen for signal sequence encoding transcripts. Journal of Pathology 210 420-430.
18. Esseghir S, Kennedy A, Seedhar P, Nerurkar A, Poulsom R, Reis-Filho JS & Isacke CM 2007 Identification of NTN4, TRA1, and STC2 as prognostic markers in breast cancer in a screen for signal sequence encoding proteins. Clinical Cancer Research 13 3164-3173.
19. Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR & Katzenellenbogen BS 2003 Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144 4562-4574.
20. Fricah A, Redeuilh G & Sabbah M 2006 Molecular cloning and characterization of the human WISP-2/CCN5 gene promoter reveal its upregalation by oestrogens. Journal of Endocrinology 191 613-624.
21. Gaasenbeek M, Gellersen B & DiMattia GE 1999 DNase I hypersensitivity analysis of non-pituitary human prolactin gene expression. Molecular and Cellular Endocrinology 152 147-159.
22. Gagliardi AD, Kuo EY, Raulic S, Wagner GF & DiMattia GE 2005 Human stanniocalcin-2 exhibits potent growth-suppressive properties in transgenic mice independently of growth hormone and IGFs. American Journal of Physiology. Endocrinology and Metabolism 288 E92-105.
23. Groves TC, Wagner GF & DiMattia GE 2001 cAMP signaling can antagonize potent glucocorticoid post-transcriptional inhibition of stanniocalcin gene expression. Journal of Endocrinology 171 499-516.
24. Gruvberger S, Ringner M, Chen Y, Panavally S, Saal LH, Borg A, Ferno M, Peterson C & Meltzer PS 2001 Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Research 61 5979-5984.
25. Guy CT, Cardiff RD & Muller WJ 1992 Induction of mammary rumors by expression of polyomavirus middle Toncogene: a transgenic mouse model for metastatic disease. Molecular and Cellular Biology 12 954-961.
26. Hall RE, Lee CS, Alexander IE, Shine J, Clarke CL & Sutherland RL 1990 Steroid hormone receptor gene expression in human breast cancer cells-inverse relationship between oesrrogen and glucocorticoid receptor messenger RNA levels. International Journal a Cancer 46 1081-1087.
27. Hyder SM, Murthy L & Stancel GM 1998 Progestin regulation of vascular endothelial growth factor in human breast cancer cells. Cancer Research 58 392-395.
28. Ito D, Walker JR, Thompson CS, Moroz I, Lin W Veselits ML, Hakim AM, Fienberg AA & Thinakaran G 2004 Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties. Molecular and Cellular Biology 24 9456 9469,
29. Iwao K, Matoba R, Ueno N, Ando A, Miyoshi Y, Matsubara K, Noguchi S & Kato K 2002 Molecular classification of primary breast tumors possessing distinct prognostic properties. Human Molecular Genetics 11 199-206.
30. Jordan VC 2007 SERMs: meeting the promise of multifunctional medicines. Journal of National Cancer Institute 99 350-356.
31. Katzenellenbogen BS & Frasor J 2004 Therapeutic targeting in the estrogen receptor hormonal pathway. Seminars in Oncolqgy 31 28-38.
32. Kedrin D, van Rheenen J, Hernandez L, Condeelis J & Segall J 2007 Cell motility and cytoskeletal regulation in invasion and metastosis. Journal of Mammary Gland Biology and Neoplasia 12 143-t52.
33. Klinge CM 2001 Estrogen receptor interaction with estrogen response elements. Nucleic Acids Research 29 2905-2919.
34. Ken Y, How LC, Hoon TF, Bajic VB, Lam TS, Agganval A, Sze HG, Bok WS, Yin WC & Tan P 2003 Classifying the estrogen receptor status of breast cancers by expression profiles reveals a poor prognosis subpopulation exhibiting high expression ofthe ERBB2 receptor. Human Molecular Genetics 12 3245-3258.
35. Kwon YS, Garcia-Bassets I, Hutt KR, Cheng CS, Jin M, Liu D, Benner C, Wang D, Ye Z, Bibikova M et al. 2007 Sensitive ChIP-DSL technology reveals all extensive estrogen receptor alpha-binding program on human gene promoters. ANAS 104 4852-4857.
36. Liang Y, Wu J, Stancel GM & Hyder SM 2005 p53-dependent inhibition of progestin-induced VEGF expression in human breast cancer cells. Journal of Steroid Biochemistry and Molecular Biology 93 173-182.
37. Lin CY, Vega VB, Thomsen JS, Zhang T, Kong SL, Xie M, Chiu KP, Lipovich L, Bartlett DH, Stossi F et al. 2007 Whole-genome cartography of estrogen receptor alpha binding sites. PLoS Genetics 3 e87.
38. Luo CW, Kawamura K, Klein C & Hsueh AJ 2004 Paracrine regulation of ovarian gramilosa cell differentiation by staindocalcin (STC) 1: mediation through specific STC1 receptors. Molecular Endocrinolcgy 18 2085-2096.
39. Luo CW, Pisarska MD & Hsueh AJ 2005 Identification of a stanniocalcin paralog, stanniocalcin-2, in fish and the paracrine actions of stanniocalcin-2 in the mammalian ovary. Endocrinology 146 469-476.
40. Madsen KL, Tavernini MM, Yachimec C, Mendrick DL, Alfonso PJ, Buergin M, Olsen HS, Antonaccio MJ, Thomson AB & Fedorak RN 1998 Stanniocalcin: a novel protein regulating calcium and phosphate transport across mammalian intestine. American Journal of Physiology 274 G96-102.
41. Magklara A, Grass L & Diamandis EP 2000 Differential steroid hormone regulation of human glandular kallikrein (hK2) and proscate-specific antigen (PSA) inbreast cancer cell lines. Breast Cancer Research and Treatment 59 263-270.
42. McCudden CR, Majewski A, Chakraborti S & Wagner GF 2004 Co-localization of stanniocalcin-1 ligand and receptor in human breast carcinomas, Molecular and Cellular Endocrinology 213 167-172.
43. McDevitt MA, Glidewell Kenney C, Weiss J, Chambon P, Jameson JL & Levine JE 2007 Estrogen response element-independent estrogen receptor (ER)-α signaling does not rescue sexual behavior but restores normal testosterone secretion in male ERalpha knockout mice. Endocrinology 148 5288-5294.
44. Moenner M, Pluquet O, Bouchecareilh M & Chevet E 2007 Integrated endoplasmic reticulum stress responses in cancer. Cancer Research 67 10631-10634.
45. Moore EE, Kuestner RE, Conklin DC, Whitmore TE, Downey W, Buddle MM, Adams RL, Bell LA, Thompson DL, Wolf A et al. 1999 Stanniocalcin 2: characterization of the protein and its localization to human pancreatic alpha cells. Hormone and Metabolic Research 31 406-414.
46. Neve RM, Chin K, Fridlyand J, Yeh J, Baelaner FL, Fevr T, Clark L, Bayani N, Coppe JF, Tong F et al. 2006 A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 10 515-527.
47. Rishi AK, Gerald TM, Shao ZM, Li XS, Baumann RG, Dawson MI & Fontana JA 1996 Regulation ofthe human retinoic acid receptor alpha gene in the estrogen receptor negative human breast carcinoma cell Imes SKBR-3 and MDA-MB-435. Cancer Research 56 5246-5252.
48. Roman SD, Clarke CL, Hall RE, Alexander IE & Sutherland RL 1992 Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Research 52 2236-2242.
49. Sahai E 2007 Illuminating the metastatic process. Nature Reviews. Cancer 7 737-749.
50. Sheikh-Hamad D, Rouse D & Yang Y 2000 Regulation of stanniocalcin in MDCK cells by hypertonicity and extracellular calcium. American Journal of Physiology Reseatch Physiology 278 F417-F424.
51. Siegel PM, Ryan ED, Cardiff RD & Muller WJ 1999 Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary rumors in transgenic mice: implications for human breast cancer. EMBO Journal 18 2149-2t64.
52. Stasko SE & Wagner GF 200t Possible roles for stanniocalcin during early skeletal patterning and joint formation in the mouse. Journal of Endocrinology 171 237-248.
53. Sutherland RL, Hall RE, Pang GY, Musgrove EA & Clarke CL 1988 Effect of medroxyprogesterone acetate on proliferation and cell cycle kinetics of human mammary carcinoma cells. Cancer Research 48 5084-5091.
54. Thierry-Mieg D & Thierry-Mieg J 2006 AceView: a comprehensive cDNA-supported gene and transcripts annotation. Genome Biology 7 S12 11-14.
55. Varghese R, Gagliardi AD, Bialek PE, Yee SP, Wagner GF & DiMattia GE 2002 Overexpression of human stanniocalcin affects growth and reproduction in transgenic mice. Endocrinology 143 868-876.
56. Wagner GF & DiMatria GE 2006 The stanniocalcin family of proteins. Journal of Experimental Zoology A Comparative Experimental Biology 305 769-780.
57. Wagner GF, Vozzolo BL, Jaworski E, Haddad M, Kline RL, Olsen HS, Rosen CA, Davidson MB & Renfro JL 1997 Human stanniocalcin inhibits renal phosphate excretion in the rat. Journal of Bone and Mineral Research 12 165-171.
58. Wilson KS, Roberts H, Leek R, Harris AL & Geradts J 2002 Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues. American Journal of Patholcgy 161 1171-1185.
59. Wintermantel TM, Berger S, Greiner EF & Schutz G 2005 Evaluation of steroid receptor function by gene targeting in mice. Journal of Steroid Biochemistsry and Molecular Biology 93 107-112.
60. Xu Z, Stokoe D, Kane LP & Weiss A 2002 The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the P13K/Akt pathway ill Jurkat T cells. Cell Growth and Diferentiation 13 285-296.
61. Yager JD & Davidson NE 2006 Estrogen carcinogenesis in breast cancer. New England Journal of Medicine 354 270-282.
62. Yamamura J, Miyoshi Y, Tamaki Y, Taguchi T, Iwao K, Monden M, Kato K & Noguchi S 2004 mRNA expression level of estrogen-inducible gene, alpha 1-antichymotrypsin, is a predictor of early tumor recurrence in patients with invasive breast cancers. Cancer Science 95 887-892.
63. Yoshiko Y, Candeliere GA, Maeda N & Aubin JE 2007 Osteoblast autonomous Pi regulation via Pit1 plays a role in bone mineralization. Molecular and Cellular Biology 27 4465-4474.
64. Yu K, Lee CH, Tan PH & Tan P 2004 Conservation ofbreast cancer molecular subtypes and transcriptional patterns of tumor progression across distinct ethnic populations. Clinical Cancer Research 10 5508-5517.
65. Zucchi I, Mento E, Kuznetsov VA, Scotti M, Valsecchi V, Simionati B, Vicinanza E, Valle G, Pilotti S, Reinhold R et al. 2004 Gene expression profiles of epithelial cells microscopically isolated from a breast-invasive ductal carcinoma and a nodal metastasis. PNAS 101 18147-18152.