Site-specific N-glycosylation analysis of human immunoglobulin e

Journal of Proteome Research

Volumn 13, Issue 2, 2014, Pages 536-546

  Plomp, Rosina ^a   Hensbergen, Paul J ^a   Rombouts, Yoann ^a   Zauner, Gerhild ^a   Dragan, Irina ^a   Koeleman, Carolien A M ^a   Deelder, André M ^a   Wuhrer, Manfred ^a,b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

antibody; cancer; glycopeptide; immunoglobulin E; myeloma; N glycosylation

Indexed keywords

CHROMATOGRAPHY, REVERSE-PHASE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN E; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84893818400     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400714w     Document Type: Article

References (34)

1. King, C. L.; Poindexter, R. W.; Ragunathan, J.; Fleisher, T. A.; Ottesen, E. A.; Nutman, T. B. Frequency analysis of IgE-secreting B lymphocytes in persons with normal or elevated serum IgE levels J. Immunol. 1991, 146 (5) 1478-83
2. Ghory, A. C.; Patterson, R.; Roberts, M.; Suszko, I. In vitro IgE formation by peripheral blood lymphocytes from normal individuals and patients with allergic bronchopulmonary aspergillosis Clin. Exp. Immunol. 1980, 40 (3) 581-5
3. Johansson, S. G. Raised levels of a new immunoglobulin class (IgND) in asthma Lancet 1967, 2 (7523) 951-3
4. Wan, T.; Beavil, R. L.; Fabiane, S. M.; Beavil, A. J.; Sohi, M. K.; Keown, M.; Young, R. J.; Henry, A. J.; Owens, R. J.; Gould, H. J.; Sutton, B. J. The crystal structure of IgE Fc reveals an asymmetrically bent conformation Nat. Immunol. 2002, 3 (7) 681-6
5. Gounni, A. S.; Lamkhioued, B.; Ochiai, K.; Tanaka, Y.; Delaporte, E.; Capron, A.; Kinet, J. P.; Capron, M. High-affinity IgE receptor on eosinophils is involved in defense against parasites Nature 1994, 367 (6459) 183-6
6. Gould, H. J.; Sutton, B. J. IgE in allergy and asthma today Nat. Rev. Immunol. 2008, 8 (3) 205-17
7. Dorrington, K. J.; Bennich, H. H. Structure-function relationships in human immunoglobulin E Immunol. Rev. 1978, 41, 3-25
8. Granato, D. A.; Neeser, J. R. Effect of trimming inhibitors on the secretion and biological activity of a murine IgE monoclonal antibody Mol. Immunol. 1987, 24 (8) 849-55
9. Platzer, B.; Ruiter, F.; van der Mee, J.; Fiebiger, E. Soluble IgE receptor-elements of the IgE network Immunol. Lett. 2011, 141 (1) 36-44
10. Bjorklund, J. E.; Karlsson, T.; Magnusson, C. G. N-Glycosylation influences epitope expression and receptor binding structures in human IgE Mol. Immunol. 1999, 36 (3) 213-21
11. Woof, J. M.; Burton, D. R. Human antibody-Fc receptor interactions illuminated by crystal structures Nat. Rev. Immunol. 2004, 4 (2) 89-99
12. Basu, M.; Hakimi, J.; Dharm, E.; Kondas, J. A.; Tsien, W. H.; Pilson, R. S.; Lin, P.; Gilfillan, A.; Haring, P.; Braswell, E. H. Purification and characterization of human recombinant IgE-Fc fragments that bind to the human high affinity IgE receptor J. Biol. Chem. 1993, 268 (18) 13118-27
13. Vercelli, D.; Helm, B.; Marsh, P.; Padlan, E.; Geha, R.; Gould, H. The B-cell binding site on human immunoglobulin E Nature 1989, 338, 649-51
14. Frigeri, L. G.; Zuberi, R. I.; Liu, F. T. Epsilon BP, a β-galactoside-binding animal lectin, recognizes IgE receptor (Fc epsilon RI) and activates mast cells Biochemistry 1993, 32 (30) 7644-9
15. Niki, T.; Tsutsui, S.; Hirose, S.; Aradono, S.; Sugimoto, Y.; Takeshita, K.; Nishi, N.; Hirashima, M. Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation J. Biol. Chem. 2009, 284 (47) 32344-52
16. Nettleton, M. Y.; Kochan, J. P. Role of glycosylation sites in the IgE Fc molecule Int. Arch. Allergy Immunol. 1995, 107 (1-3) 328-9
17. Baenziger, J.; Kornfeld, S.; Kochwa, S. Structure of the carbohydrate units of IgE immunoglobulin: II. Sequence of the sialic acid-containing glycopeptides J. Biol. Chem. 1974, 249 (6) 1897-1903
18. Baenziger, J.; Kornfeld, S.; Kochwa, S. Structure of the carbohydrate units of IgE immunoglobulin: I. Over-all composition, glycopeptide isolation, and structure of the high mannose oligosaccharide unit J. Biol. Chem. 1974, 249 (6) 1889-96
19. Fridriksson, E. K.; Beavil, A.; Holowka, D.; Gould, H. J.; Baird, B.; McLafferty, F. W. Heterogeneous glycosylation of immunoglobulin E constructs characterized by top-down high-resolution 2-D mass spectrometry† Biochemistry 2000, 39 (12) 3369-76
20. Arnold, J. N.; Radcliffe, C. M.; Wormald, M. R.; Royle, L.; Harvey, D. J.; Crispin, M.; Dwek, R. A.; Sim, R. B.; Rudd, P. M. The glycosylation of human serum IgD and IgE and the accessibility of identified oligomannose structures for interaction with mannan-binding lectin J. Immunol. 2004, 173 (11) 6831-40
21. Robertson, M. W.; Liu, F. T. Heterogeneous IgE glycoforms characterized by differential recognition of an endogenous lectin (IgE-binding protein) J. Immunol. 1991, 147 (9) 3024-30
22. Huddleston, M. J.; Bean, M. F.; Carr, S. A. Collisional fragmentation of glycopeptides by electrospray ionization LC/MS and LC/MS/MS: methods for selective detection of glycopeptides in protein digests Anal. Chem. 1993, 65 (7) 877-84
23. Sullivan, B.; Addona, T. A.; Carr, S. A. Selective detection of glycopeptides on ion trap mass spectrometers Anal. Chem. 2004, 76 (11) 3112-8
24. Wuhrer, M.; Catalina, M. I.; Deelder, A. M.; Hokke, C. H. Glycoproteomics based on tandem mass spectrometry of glycopeptides J. Chromatogr., B 2007, 849 (1-2) 115-28
25. Mizuochi, T.; Taniguchi, T.; Shimizu, A.; Kobata, A. Structural and numerical variations of the carbohydrate moiety of immunoglobulin G J. Immunol. 1982, 129 (5) 2016-20
26. Lauc, G.; Huffman, J. E.; Pucic, M.; Zgaga, L.; Adamczyk, B.; Muzinic, A.; Novokmet, M.; Polasek, O.; Gornik, O.; Kristic, J.; Keser, T.; Vitart, V.; Scheijen, B.; Uh, H. W.; Molokhia, M.; Patrick, A. L.; McKeigue, P.; Kolcic, I.; Lukic, I. K.; Swann, O.; van Leeuwen, F. N.; Ruhaak, L. R.; Houwing-Duistermaat, J. J.; Slagboom, P. E.; Beekman, M.; de Craen, A. J.; Deelder, A. M.; Zeng, Q.; Wang, W.; Hastie, N. D.; Gyllensten, U.; Wilson, J. F.; Wuhrer, M.; Wright, A. F.; Rudd, P. M.; Hayward, C.; Aulchenko, Y.; Campbell, H.; Rudan, I. Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers PLoS Genet. 2013, 9 (1) e1003225
27. Krokhin, O. V.; Antonovici, M.; Ens, W.; Wilkins, J. A.; Standing, K. G. Deamidation of -Asn-Gly- sequences during sample preparation for proteomics: Consequences for MALDI and HPLC-MALDI analysis Anal. Chem. 2006, 78 (18) 6645-50
28. Balog, C. I.; Stavenhagen, K.; Fung, W. L.; Koeleman, C. A.; McDonnell, L. A.; Verhoeven, A.; Mesker, W. E.; Tollenaar, R. A.; Deelder, A. M.; Wuhrer, M. N-Glycosylation of colorectal cancer tissues: a liquid chromatography and mass spectrometry-based investigation Mol. Cell. Proteomics 2012, 11 (9) 571-85
29. Stavenhagen, K.; Hinneburg, H.; Thaysen-Andersen, M.; Hartmann, L.; Varon Silva, D.; Fuchser, J.; Kaspar, S.; Rapp, E.; Seeberger, P. H.; Kolarich, D. Quantitative mapping of glycoprotein micro-heterogeneity and macro-heterogeneity: an evaluation of mass spectrometry signal strengths using synthetic peptides and glycopeptides J. Mass Spectrom. 2013, 48 (6) 627-39
30. Ferrara, C.; Grau, S.; Jager, C.; Sondermann, P.; Brunker, P.; Waldhauer, I.; Hennig, M.; Ruf, A.; Rufer, A. C.; Stihle, M.; Umana, P.; Benz, J. Unique carbohydrate-carbohydrate interactions are required for high affinity binding between FcgammaRIII and antibodies lacking core fucose Proc. Natl. Acad. Sci. U.S.A. 2011, 108 (31) 12669-74
31. Arnold, J. N.; Wormald, M. R.; Sim, R. B.; Rudd, P. M.; Dwek, R. A. The impact of glycosylation on the biological function and structure of human immunoglobulins Annu. Rev. Immunol. 2007, 25, 21-50
32. Jefferis, R.; Lund, J.; Pound, J. D. IgG-Fc-mediated effector functions: molecular definition of interaction sites for effector ligands and the role of glycosylation Immunol. Rev. 1998, 163, 59-76
33. Sondermann, P.; Pincetic, A.; Maamary, J.; Lammens, K.; Ravetch, J. V. General mechanism for modulating immunoglobulin effector function Proc. Natl. Acad. Sci. U.S.A. 2013, 110 (24) 9868-72
34. Heemskerk, A. A.; Wuhrer, M.; Busnel, J. M.; Koeleman, C. A.; Selman, M. H.; Vidarsson, G.; Kapur, R.; Schoenmaker, B.; Derks, R. J.; Deelder, A. M.; Mayboroda, O. A. Coupling porous sheathless interface MS with transient-ITP in neutral capillaries for improved sensitivity in glycopeptide analysis Electrophoresis 2013, 34 (3) 383-7