메뉴 건너뛰기




Volumn 25, Issue 5, 2015, Pages 259-262

A twin study of the trough plasma steady-state concentration of metformin

Author keywords

metformin; pharmacogenetics; pharmacokinetics; twin study

Indexed keywords

METFORMIN;

EID: 84928249651     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0000000000000133     Document Type: Article
Times cited : (16)

References (34)
  • 1
    • 84903524608 scopus 로고    scopus 로고
    • Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
    • Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, et al. Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature 2014; 510:542-546.
    • (2014) Nature , vol.510 , pp. 542-546
    • Madiraju, A.K.1    Erion, D.M.2    Rahimi, Y.3    Zhang, X.M.4    Braddock, D.T.5    Albright, R.A.6
  • 3
    • 0031472452 scopus 로고    scopus 로고
    • Efficacy of metformin in type II diabetes: Results of a double-blind, placebo-controlled, dose-response trial
    • Garber AJ, Duncan TG, Goodman AM, Mills DJ, Rohlf JL. Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial. Am J Med 1997; 103:491-497.
    • (1997) Am J Med , vol.103 , pp. 491-497
    • Garber, A.J.1    Duncan, T.G.2    Goodman, A.M.3    Mills, D.J.4    Rohlf, J.L.5
  • 6
    • 84885148050 scopus 로고    scopus 로고
    • Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters
    • Grün B, Kiessling MK, Burhenne J, Riedel KD, Weiss J, Rauch G, et al. Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters. Br J Clin Pharmacol 2013; 76:787-796.
    • (2013) Br J Clin Pharmacol , vol.76 , pp. 787-796
    • Grün, B.1    Kiessling, M.K.2    Burhenne, J.3    Riedel, K.D.4    Weiss, J.5    Rauch, G.6
  • 7
    • 84920936873 scopus 로고    scopus 로고
    • Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine
    • Johansson S, Read J, Oliver S, Steinberg M, Li Y, Lisbon E, et al. Pharmacokinetic evaluations of the co-administrations of vandetanib and metformin, digoxin, midazolam, omeprazole or ranitidine. Clin Pharmacokinet 2014; 53:837-847.
    • (2014) Clin Pharmacokinet , vol.53 , pp. 837-847
    • Johansson, S.1    Read, J.2    Oliver, S.3    Steinberg, M.4    Li, Y.5    Lisbon, E.6
  • 8
    • 84941142541 scopus 로고    scopus 로고
    • Intake of St. John's wort improves the glucose tolerance in healthy subjects that ingest metformin compared to metformin alone
    • Stage TB, Pedersen RS, Damkier P, Christensen MMH, Feddersen S, Larsen JT, et al. Intake of St. John's wort improves the glucose tolerance in healthy subjects that ingest metformin compared to metformin alone. Br J Clin Pharmacol 2015; 79:298-306.
    • (2015) Br J Clin Pharmacol , vol.79 , pp. 298-306
    • Stage, T.B.1    Pedersen, R.S.2    Damkier, P.3    Mmh, C.4    Feddersen, S.5    Larsen, J.T.6
  • 9
    • 79951812086 scopus 로고    scopus 로고
    • Rifampin enhances the glucose-lowering effect of metformin and increases OCT1 mRNA levels in healthy participants
    • Cho SK, Yoon JS, Lee MG, Lee DH, Lim LA, Park K, et al. Rifampin enhances the glucose-lowering effect of metformin and increases OCT1 mRNA levels in healthy participants. Clin Pharmacol Ther 2011; 89:416-421.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 416-421
    • Cho, S.K.1    Yoon, J.S.2    Lee, M.G.3    Lee, D.H.4    Lim, L.A.5    Park, K.6
  • 10
    • 84919328872 scopus 로고    scopus 로고
    • Verapamil decreases the glucoselowering effect of metformin in healthy volunteers
    • Cho SK, Kim CO, Park ES, Chung JY. Verapamil decreases the glucoselowering effect of metformin in healthy volunteers. Br J Clin Pharmacol 2014; 78:1426-1432.
    • (2014) Br J Clin Pharmacol , vol.78 , pp. 1426-1432
    • Cho, S.K.1    Kim, C.O.2    Park, E.S.3    Chung, J.Y.4
  • 11
    • 34248156160 scopus 로고    scopus 로고
    • Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action
    • Shu Y, Sheardown SA, Brown C, Owen RP, Zhang S, Castro RA, et al. Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest 2007; 117:1422-1431.
    • (2007) J Clin Invest , vol.117 , pp. 1422-1431
    • Shu, Y.1    Sheardown, S.A.2    Brown, C.3    Owen, R.P.4    Zhang, S.5    Castro, R.A.6
  • 12
    • 38349085099 scopus 로고    scopus 로고
    • Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics
    • Shu Y, Brown C, Castro RA, Shi RJ, Lin ET, Owen RP, et al. Effect of genetic variation in the organic cation transporter 1, OCT1, on metformin pharmacokinetics. Clin Pharmacol Ther 2008; 83:273-280.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 273-280
    • Shu, Y.1    Brown, C.2    Castro, R.A.3    Shi, R.J.4    Lin, E.T.5    Owen, R.P.6
  • 13
    • 69449098951 scopus 로고    scopus 로고
    • The effects of genetic polymorphisms in the organic cation transporters OCT1 OCT2, and OCT3 on the renal clearance of metformin
    • Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, et al. The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin. Clin Pharmacol Ther 2009; 86:299-306.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 299-306
    • Tzvetkov, M.V.1    Vormfelde, S.V.2    Balen, D.3    Meineke, I.4    Schmidt, T.5    Sehrt, D.6
  • 14
    • 67849116869 scopus 로고    scopus 로고
    • Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus
    • Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus. Pharmacogenomics J 2009; 9:242-247.
    • (2009) Pharmacogenomics J , vol.9 , pp. 242-247
    • Becker, M.L.1    Visser, L.E.2    Van Schaik, R.H.3    Hofman, A.4    Uitterlinden, A.G.5    Stricker, B.H.6
  • 15
    • 53049095113 scopus 로고    scopus 로고
    • OCT2 polymorphisms and in-vivo renal functional consequence: Studies with metformin and cimetidine
    • Wang ZJ, Yin OQ, Tomlinson B, Chow MS. OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine. Pharmacogenet Genomics 2008; 18:637-645.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 637-645
    • Wang, Z.J.1    Yin, O.Q.2    Tomlinson, B.3    Chow, M.S.4
  • 17
    • 67651235787 scopus 로고    scopus 로고
    • Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin
    • Chen Y, Li S, Brown C, Cheatham S, Castro RA, Leabman MK, et al. Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin. Pharmacogenet Genomics 2009; 19:497-504.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 497-504
    • Chen, Y.1    Li, S.2    Brown, C.3    Cheatham, S.4    Castro, R.A.5    Leabman, M.K.6
  • 18
    • 84871937263 scopus 로고    scopus 로고
    • Pharmacogenomic association between a variant in SLC47A1 gene and therapeutic response to metformin in type 2 diabetes
    • Tká? I, Klim?áková L, Javorský M, Fabianová M, Schroner Z, Hermanová H, et al. Pharmacogenomic association between a variant in SLC47A1 gene and therapeutic response to metformin in type 2 diabetes. Diabetes Obes Metab 2013; 15:189-191.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 189-191
    • Tká, I.1    Klimáková, L.2    Javorský, M.3    Fabianová, M.4    Schroner, Z.5    Hermanová, H.6
  • 19
    • 84872679649 scopus 로고    scopus 로고
    • The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin
    • Stocker SL, Morrissey KM, Yee SW, Castro RA, Xu L, Dahlin A, et al. The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther 2013; 93:186-194.
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 186-194
    • Stocker, S.L.1    Morrissey, K.M.2    Yee, S.W.3    Castro, R.A.4    Xu, L.5    Dahlin, A.6
  • 20
    • 79251612707 scopus 로고    scopus 로고
    • GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group; Wellcome Trust Case Control Consortium 2; MAGIC investigators Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
    • Zhou K, Bellenguez C, Spencer CC, Bennett AJ, Coleman RL, Tavendale R, et al. GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group; Wellcome Trust Case Control Consortium 2; MAGIC investigators. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet 2011; 43:117-120.
    • (2011) Nat Genet , vol.43 , pp. 117-120
    • Zhou, K.1    Bellenguez, C.2    Spencer, C.C.3    Bennett, A.J.4    Coleman, R.L.5    Tavendale, R.6
  • 21
    • 84866319096 scopus 로고    scopus 로고
    • A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: A replication and meta-analysis of five cohorts
    • Van Leeuwen N, Nijpels G, Becker ML, Deshmukh H, Zhou K, Stricker BH, et al. A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts. Diabetologia 2012; 55:1971-1977.
    • (2012) Diabetologia , vol.55 , pp. 1971-1977
    • Van Leeuwen, N.1    Nijpels, G.2    Becker, M.L.3    Deshmukh, H.4    Zhou, K.5    Stricker, B.H.6
  • 24
    • 70450253101 scopus 로고    scopus 로고
    • Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins
    • Birkenfeld AL, Jordan J, Hofmann U, Busjahn A, Franke G, Krüger N, et al. Genetic influences on the pharmacokinetics of orally and intravenously administered digoxin as exhibited by monozygotic twins. Clin Pharmacol Ther 2009; 86:605-608.
    • (2009) Clin Pharmacol Ther , vol.86 , pp. 605-608
    • Birkenfeld, A.L.1    Jordan, J.2    Hofmann, U.3    Busjahn, A.4    Franke, G.5    Krüger, N.6
  • 26
    • 84897074091 scopus 로고    scopus 로고
    • Quantitation of metformin in human plasma and urine by hydrophilic interaction liquid chromatography and application to a pharmacokinetic study
    • Nielsen F, Christensen MM, Brøsen K. Quantitation of metformin in human plasma and urine by hydrophilic interaction liquid chromatography and application to a pharmacokinetic study. Ther Drug Monit 2014; 36:211-217.
    • (2014) Ther Drug Monit , vol.36 , pp. 211-217
    • Nielsen, F.1    Christensen, M.M.2    Brøsen, K.3
  • 27
    • 33645749049 scopus 로고    scopus 로고
    • On the probability of dizygotic twins being concordant for two alleles at multiple polymorphic loci
    • Nyholt DR. On the probability of dizygotic twins being concordant for two alleles at multiple polymorphic loci. Twin Res Hum Genet 2006; 9:194-197.
    • (2006) Twin Res Hum Genet , vol.9 , pp. 194-197
    • Nyholt, D.R.1
  • 29
    • 0036667961 scopus 로고    scopus 로고
    • The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors
    • Rasmussen BB, Brix TH, Kyvik KO, Brøsen K. The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors. Pharmacogenetics 2002; 12:473-478.
    • (2002) Pharmacogenetics , vol.12 , pp. 473-478
    • Rasmussen, B.B.1    Brix, T.H.2    Kyvik, K.O.3    Brøsen, K.4
  • 30
    • 0022589555 scopus 로고
    • A twin study of human obesity
    • Stunkard AJ, Foch TT, Hrubec Z. A twin study of human obesity. JAMA 1986; 256:51-54.
    • (1986) JAMA , vol.256 , pp. 51-54
    • Stunkard, A.J.1    Foch, T.T.2    Hrubec, Z.3
  • 31
    • 84886992019 scopus 로고    scopus 로고
    • Population pharmacokinetics of metformin in healthy subjects and patients with type 2 diabetes mellitus: Simulation of doses according to renal function
    • Duong JK, Kumar SS, Kirkpatrick CM, Greenup LC, Arora M, Lee TC, et al. Population pharmacokinetics of metformin in healthy subjects and patients with type 2 diabetes mellitus: simulation of doses according to renal function. Clin Pharmacokinet 2013; 52:373-384.
    • (2013) Clin Pharmacokinet , vol.52 , pp. 373-384
    • Duong, J.K.1    Kumar, S.S.2    Kirkpatrick, C.M.3    Greenup, L.C.4    Arora, M.5    Lee, T.C.6
  • 32
    • 84864287169 scopus 로고    scopus 로고
    • Population pharmacokinetics of metformin in obese and non-obese patients with type 2 diabetes mellitus
    • Bardin C, Nobecourt E, Larger E, Chast F, Treluyer JM, Urien S. Population pharmacokinetics of metformin in obese and non-obese patients with type 2 diabetes mellitus. Eur J Clin Pharmacol 2012; 68:961-968.
    • (2012) Eur J Clin Pharmacol , vol.68 , pp. 961-968
    • Bardin, C.1    Nobecourt, E.2    Larger, E.3    Chast, F.4    Treluyer, J.M.5    Urien, S.6
  • 33
    • 0014693146 scopus 로고
    • Steady-state plasma levels of nortriptyline in twins: Influence of genetic factors and drug therapy
    • Alexanderson B, Evans DA, Sjöqvist F. Steady-state plasma levels of nortriptyline in twins: influence of genetic factors and drug therapy. Br Med J 1969; 4:764-768.
    • (1969) Br Med J , vol.4 , pp. 764-768
    • Alexanderson, B.1    Evans, D.A.2    Sjöqvist, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.