Quantitative evaluation of the pulmonary microdistribution of TiO2 nanoparticles using X-ray fluorescence microscopy after intratracheal administration with a microsprayer in rats

Journal of Applied Toxicology

Volumn 35, Issue 6, 2015, Pages 623-630

  Zhang, Guihua ^a   Shinohara, Naohide ^a   Kano, Hirokazu ^b   Senoh, Hideki ^b   Suzuki, Masaaki ^b   Sasaki, Takeshi ^a   Fukushima, Shoji ^b   Gamo, Masashi ^a  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b Japan Bioassay Research Center   (Japan)

Author keywords

Intratracheal administration; Pulmonary distribution; Rat; Ti reference; TiO2; XRF

Indexed keywords

TITANIUM DIOXIDE NANOPARTICLE; METAL NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EVALUATION STUDY; FLUORESCENCE MICROSCOPY; LIMIT OF DETECTION; MALE; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REPRODUCIBILITY; RESPIRATORY SYSTEM; SUSPENSION; TOXICITY TESTING; X RAY FLUORESCENCE MICROSCOPY; ANIMAL; CHEMISTRY; ELECTRON PROBE MICROANALYSIS; FISCHER 344 RAT; INHALATIONAL DRUG ADMINISTRATION; LUNG; METABOLISM;

RATTUS;

ADMINISTRATION, INHALATION; ANIMALS; ELECTRON PROBE MICROANALYSIS; LUNG; MALE; METAL NANOPARTICLES; MICROSCOPY, FLUORESCENCE; RATS; RATS, INBRED F344; TITANIUM;

EID: 84928212190     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.3109     Document Type: Article

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