Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice

Hepatology

Volumn 61, Issue 5, 2015, Pages 1660-1671

  Hatano, Ryo ^a   Akiyama, Kaori ^a   Tamura, Atsushi ^b   Hosogi, Shigekuni ^c   Marunaka, Yoshinori ^c   Caplan, Michael J ^d   Ueno, Yoshiyuki ^e   Tsukita, Sachiko ^b   Asano, Shinji ^a  

^a RITSUMEIKAN UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e YAMAGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANION EXCHANGER 2; AQUAPORIN 1; ASPARTATE AMINOTRANSFERASE; BICARBONATE; BILE ACID; CHLORIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CYTOKERATIN 19; CYTOSKELETON PROTEIN; EZRIN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MACROPHAGE INFLAMMATORY PROTEIN 2 ALPHA; MESSENGER RNA; MOESIN; PROCOLLAGEN C PROTEINASE; PROCOLLAGEN TYPE 3 AMINOPROPEPTIDE; RADIXIN; SCAFFOLD PROTEIN; SODIUM PROTON EXCHANGE PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID BLOOD LEVEL; BILE DUCT; BILE DUCT DISEASE; BILE FLOW; BILE FLUIDITY; CELL IMMORTALIZATION; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHLORIDE TRANSPORT; CONTROLLED STUDY; DIGESTIVE TRACT PARAMETERS; DISEASE SEVERITY; ENDOPLASMIC RETICULUM; GENE SILENCING; IMMUNOBLOTTING; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; INTRAHEPATIC BILE DUCT; INTRAHEPATIC CHOLESTASIS; LIVER FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN TRANSPORT; STABLE EXPRESSION; SURFACE PROPERTY; UPREGULATION; ANIMAL; BILE; EPITHELIUM; FIBROSIS; GENETICS; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; BILE; BILE DUCTS; CHOLESTASIS, INTRAHEPATIC; CYTOSKELETAL PROTEINS; EPITHELIUM; FIBROSIS; MICE; MICE, KNOCKOUT;

EID: 84928205505     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27565     Document Type: Article

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