Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 3, 2015, Pages 701-709

  Stentz, Régis ^a   Horn, Nikki ^a   Cross, Kathryn ^a   Salt, Louise ^a   Brearley, Charles ^b   Livermore, David M ^c   Carding, Simon R ^a,c  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

Gut microbiota; Protective effect; Salmonella; lactamases

Indexed keywords

AMPICILLIN; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFOTAXIME; CEFPODOXIME; CEPHALOSPORINASE; CLAVULANIC ACID; ANTIINFECTIVE AGENT; BACTERIAL DNA; BETA LACTAM;

AMINO ACID SEQUENCE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL OUTER MEMBRANE; BACTEROIDES; BACTEROIDES FRAGILIS; BACTEROIDES OVATUS; BACTEROIDES THETAIOTAOMICRON; BIFIDOBACTERIUM BREVE; COMMENSAL; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVITY; INTESTINE FLORA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYLOGENETIC TREE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; BIFIDOBACTERIUM; BIOTRANSFORMATION; CHEMISTRY; CLUSTER ANALYSIS; DNA SEQUENCE; DRUG EFFECTS; ENZYMOLOGY; EXOSOME; GASTROINTESTINAL TRACT; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; HYDROLYSIS; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; MICROBIOLOGY; ORGANISMAL INTERACTION; PHYLOGENY; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY;

ANTI-BACTERIAL AGENTS; BACTEROIDES; BETA-LACTAMS; BIFIDOBACTERIUM; BIOTRANSFORMATION; CEPHALOSPORINASE; CLUSTER ANALYSIS; DNA, BACTERIAL; EXOSOMES; GASTROINTESTINAL TRACT; HUMANS; HYDROLYSIS; MICROBIAL INTERACTIONS; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; PHYLOGENY; SALMONELLA TYPHIMURIUM; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY;

EID: 84928171161     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dku466     Document Type: Article

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