Potential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles

International Journal of Nanomedicine

Volumn 10, Issue , 2015, Pages 2751-2763

  Yong, Chean Yeah ^a   Yeap, Swee Keong ^a   Ho, Kok Lian ^a   Omar, Abdul Rahman ^a   Tan, Wen Siang ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Fusion protein; Immunogenicity; Matrix 2 ectodomain; Nodavirus capsid; Subunit vaccine; Virus like particle

Indexed keywords

CAPSID PROTEIN; CHIMERIC PROTEIN; CYTOKINE; HYBRID PROTEIN; INFLUENZA VACCINE; NANOPARTICLE; RECOMBINANT VACCINE; M2 PROTEIN, INFLUENZA A VIRUS; MATRIX PROTEIN;

ANTIBODY TITER; ANTIGENICITY; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG RESPONSE; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IMMUNE RESPONSE; IMMUNOPHENOTYPING; INFECTION PREVENTION; INFLUENZA A; INFLUENZA VACCINATION; INFLUENZA VIRUS A; MACROBRACHIUM ROSENBERGII; NODAVIRUS; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; VIRUS CAPSID; VIRUS IDENTIFICATION; VIRUS LIKE AGENT; VIRUS STRAIN; AMINO ACID SEQUENCE; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETICS; IMMUNOLOGY; INFLUENZA A VIRUS; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; ORTHOMYXOVIRIDAE INFECTIONS; TRANSMISSION ELECTRON MICROSCOPY; VACCINATION; VIROLOGY; WESTERN BLOTTING;

INFLUENZA A VIRUS; MACROBRACHIUM ROSENBERGII; MIRIDAE; MUS; NODAVIRIDAE; ORTHOMYXOVIRIDAE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CAPSID PROTEINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNOPHENOTYPING; INFLUENZA A VIRUS; INFLUENZA VACCINES; MICE; MICE, INBRED BALB C; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; NANOPARTICLES; ORTHOMYXOVIRIDAE INFECTIONS; RECOMBINANT FUSION PROTEINS; VACCINATION; VACCINES, SYNTHETIC; VIRAL MATRIX PROTEINS;

EID: 84928139655     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S77405     Document Type: Article

References (35)

1. Dawood FS, Iuliano AD, Reed C, et al. Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study. Lancet Infect Dis. 2012;12(9):687-695.
2. De Filette M, Ramne A, Birkett A, et al. The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection. Vaccine. 2006;24(5):544-551.
3. Cox NJ, Subbarao K. Influenza. Lancet. 1999;354(9186):1277-1282.
4. Reed C, Meltzer MI, Finelli L, Fiore A. Public health impact of including two lineages of influenza B in a quadrivalent seasonal influenza vaccine. Vaccine. 2012;30(11):1993-1998.
5. Fang R, Min Jou W, Huylebroeck D, Devos R, Fiers W. Complete structure of A/duck/Ukraine/63 influenza hemagglutinin gene: animal virus as progenitor of human H3 Hong Kong 1968 influenza hemagglutinin. Cell. 1981;25(2):315-323.
6. Lamb RA, Lai CJ, Choppin PW. Sequences of mRNAs derived from genome RNA segment 7 of influenza virus: colinear and interrupted mRNAs code for overlapping proteins. Proc Natl Acad Sci U S A. 1981;78(7):4170-4174.
7. Rossman JS, Lamb RA. Influenza virus assembly and budding. Virology. 2011;411(2):229-236.
8. Schnell JR, Chou JJ. Structure and mechanism of the M2 proton channel of influenza A virus. Nature. 2008;451(7178):591-595.
9. Stouffer AL, Acharya R, Salom D, et al. Structural basis for the function and inhibition of an influenza virus proton channel. Nature. 2008;451(7178):596-599.
10. Fiers W, De Filette M, El Bakkouri K, et al. M2e-based universal influenza A vaccine. Vaccine. 2009;27(45):6280-6283.
11. Feng J, Zhang M, Mozdzanowska K, et al. Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2. Virol J. 2006;3:102.
12. Goh ZH, Tan SG, Bhassu S, Tan WS. Virus-like particles of Macrobrachium rosenbergii nodavirus produced in bacteria. J Virol Methods. 2011;175(1):74-79.
13. Ho CW, Chew TK, Ling TC, et al. Efficient mechanical cell disruption of Escherichia coli by an ultrasonicator and recovery of intracellular hepatitis B core antigen. Process Biochem. 2006;41(8):1829-1834.
14. Yap WB, Tey BT, Alitheen NB, Tan WS. Purification of the His-tagged hepatitis B core antigen from unclarified bacterial homogenate using immobilized metal affinity-expanded bed adsorption chromatography. J Chromatogr A. 2010;1217(21):3473-3480.
15. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72(1-2):248-254.
16. Gao X, Wang W, Li Y, et al. Enhanced Influenza VLP vaccines comprising matrix-2 ectodomain and nucleoprotein epitopes protects mice from lethal challenge. Antiviral Res. 2013;98(1):4-11.
17. Ibañez LI, Roose K, De Filette M, et al. M2e-displaying virus-like particles with associated RNA promote T helper 1 type adaptive immunity against influenza A. PLoS One. 2013;8(3):e59081.
18. Price GE, Soboleski MR, Lo CY, et al. Single-dose mucosal immunization with a candidate universal influenza vaccine provides rapid protection from virulent H5N1, H3N2 and H1N1 viruses. PLoS One. 2010;5(10):e13162.
19. Lamb RA, Zebedee SL, Richardson CD. Influenza virus M2 protein is an integral membrane protein expressed on the infected-cell surface. Cell. 1985;40(3):627-633.
20. Black RA, Rota PA, Gorodkova N, Klenk HD, Kendal AP. Antibody response to the M2 protein of influenza A virus expressed in insect cells. J Gen Virol. 1993;74 Pt 1:143-146.
21. Liu W, Li H, Chen YH. N terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication. FEMS Immunol Med Microbiol. 2003;35(2):141-146.
22. De Filette M, Min Jou W, Birkett A, et al. Universal influenza A vaccine: optimization of M2-based constructs. Virology. 2005;337(1): 149-161.
23. Neirynck S, Deroo T, Saelens X, Vanlandschoot P, Jou WM, Fiers W. A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat Med. 1999;5(10):1157-1163.
24. El Bakkouri K, Descamps F, De Filette M, et al. Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection. J Immunol. 2011;186(2): 1022-1031.
25. Dong L, Mori I, Hossain MJ, Kimura Y. The senescence-accelerated mouse shows aging-related defects in cellular but not humoral immunity against influenza virus infection. J Infect Dis. 2000;182(2):391-396.
26. Baumgarth N, Kelso A. In vivo blockade of gamma interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue. J Virol. 1996;70(7):4411-4418.
27. Fiers W, De Filette M, Birkett A, Neirynck S, Min Jou W. A "universal" human influenza A vaccine. Virus Res. 2004;103(1-2):173-176.
28. Hashemi H, Pouyanfard S, Bandehpour M, et al. Immunization with M2e-displaying T7 bacteriophage nanoparticles protects against influenza A virus challenge. PLoS One. 2012;7(9):e45765.
29. He XS, Draghi M, Mahmood K, et al. T cell-dependent production of IFN-gamma by NK cells in response to influenza A virus. J Clin Invest. 2004;114(12):1812-1819.
30. Liu B, Mori I, Hossain MJ, Dong L, Takeda K, Kimura Y. Interleukin-18 improves the early defence system against influenza virus infection by augmenting natural killer cell-mediated cytotoxicity. J Gen Virol. 2004;85 Pt 2:423-428.
31. Weiss ID, Wald O, Wald H, et al. IFN-gamma treatment at early stages of influenza virus infection protects mice from death in a NK cell-dependent manner. J Interferon Cytokine Res. 2010;30(6):439-449.
32. Bordignon V, Cordiali-Fei P, Rinaldi M, et al. Evaluation of antigen specific recognition and cell mediated cytotoxicity by a modified lysispot assay in a rat colon carcinoma model. J Exp Clin Cancer Res. 2012;31:9.
33. Karulin AY, Hesse MD, Tary-Lehmann M, Lehmann PV. Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity. J Immunol. 2000;164(4):1862-1872.
34. + T cells specific to a single viral epitope. J Immunol. 2000;165(11):6214-6220.
35. + T cells. Nature. 1999;401(6748): 76-79.