메뉴 건너뛰기




Volumn 16, Issue 4, 2015, Pages 8744-8760

Addition of interleukin-21 for expansion of T-cells for adoptive immunotherapy of murine melanoma

Author keywords

Adoptive immunotherapy; IL 15; IL 2; IL 21; IL 7; Melanoma

Indexed keywords

BRYOSTATIN 1; GAMMA INTERFERON; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 21; INTERLEUKIN 7; IONOMYCIN; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN DERIVATIVE;

EID: 84928139237     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms16048744     Document Type: Article
Times cited : (7)

References (41)
  • 2
    • 77953101577 scopus 로고    scopus 로고
    • Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T Cells. Cancer Immunol
    • Pouw, N.; Treffers-Westerlaken, E.; Kraan, J.; Wittink, F.; ten Hagen, T.; Verweij, J.; Debets, R. Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T Cells. Cancer Immunol. Immunother. 2010, 59, 921–931.
    • (2010) Immunother , vol.59 , pp. 921-931
    • Pouw, N.1    Treffers-Westerlaken, E.2    Kraan, J.3    Wittink, F.4    Ten Hagen, T.5    Verweij, J.6    Debets, R.7
  • 4
    • 0034913993 scopus 로고    scopus 로고
    • Adoptive immunotherapy of cancer with pharmacologically activated lymph node lymphocytes: A pilot clinical trial
    • Bear, H.D.; Roberts, J.; Cornell, D.; Tombes, M.B.; Kyle, B. Adoptive immunotherapy of cancer with pharmacologically activated lymph node lymphocytes: A pilot clinical trial. Cancer Immunol. Immunother. 2001, 50, 269–274.
    • (2001) Cancer Immunol. Immunother , vol.50 , pp. 269-274
    • Bear, H.D.1    Roberts, J.2    Cornell, D.3    Tombes, M.B.4    Kyle, B.5
  • 5
    • 33746102229 scopus 로고    scopus 로고
    • Comparison of common γ-chain cytokines, interleukin-2, interleukin-7, and interleukin-15 for the in vitro generation of human tumor-reactive T lymphocytes for adoptive cell transfer therapy
    • Liu, S.; Riley, J.; Rosenberg, S.; Parkhurst, M. Comparison of common γ-chain cytokines, interleukin-2, interleukin-7, and interleukin-15 for the in vitro generation of human tumor-reactive T lymphocytes for adoptive cell transfer therapy. J. Immunother. 2006, 29, 284–293.
    • (2006) J. Immunother , vol.29 , pp. 284-293
    • Liu, S.1    Riley, J.2    Rosenberg, S.3    Parkhurst, M.4
  • 6
    • 68549106145 scopus 로고    scopus 로고
    • Incubation of antigen-sensitized T lymphocytes activated with bryostatin 1 + ionomycin in IL-7 + IL-15 increases yield of cells capable of inducing regression of melanoma metastases compared to culture in IL-2
    • Le, H.K.; Graham, L.; Miller, C.H.; Kmieciak, M.; Manjili, M.H.; Bear, H.D. Incubation of antigen-sensitized T lymphocytes activated with bryostatin 1 + ionomycin in IL-7 + IL-15 increases yield of cells capable of inducing regression of melanoma metastases compared to culture in IL-2. Cancer Immunol. Immunother. 2009, 58, 1565–1576.
    • (2009) Cancer Immunol. Immunother , vol.58 , pp. 1565-1576
    • Le, H.K.1    Graham, L.2    Miller, C.H.3    Kmieciak, M.4    Manjili, M.H.5    Bear, H.D.6
  • 7
    • 0024328679 scopus 로고
    • Mechanisms of T cell activation by the calcium ionophore ionomycin
    • Chatila, T.; Silverman, L.; Miller, R.; Geha, R. Mechanisms of T cell activation by the calcium ionophore ionomycin. J. Immunol. 1989, 143, 1283–1289.
    • (1989) J. Immunol , vol.143 , pp. 1283-1289
    • Chatila, T.1    Silverman, L.2    Miller, R.3    Geha, R.4
  • 8
    • 0028167842 scopus 로고
    • Binding of [26–3H]bryostatin 1 and analogs to calcium-dependent and calcium-independent protein kinase C isozymes
    • Kazanietz, M.G.; Lewin, N.E.; Gao, F.; Pettit, G.R.; Blumberg, P.M. Binding of [26–3H]bryostatin 1 and analogs to calcium-dependent and calcium-independent protein kinase C isozymes. Mol. Pharmacol. 1994, 46, 374–379.
    • (1994) Mol. Pharmacol , vol.46 , pp. 374-379
    • Kazanietz, M.G.1    Lewin, N.E.2    Gao, F.3    Pettit, G.R.4    Blumberg, P.M.5
  • 10
    • 84888286401 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cells of patients with breast cancer can be reprogrammed to enhance anti-HER-2/Neu reactivity and overcome myeloid-derived suppressor cells
    • Payne, K.K.; Zoon, C.K.; Wan, W.; Marlar, K.; Keim, R.C.; Kenari, M.N.; Kazim, A.L.; Bear, H.D.; Manjili, M.H. Peripheral blood mononuclear cells of patients with breast cancer can be reprogrammed to enhance anti-HER-2/Neu reactivity and overcome myeloid-derived suppressor cells. Breast Cancer Res. Treat. 2013, 142, 45–57.
    • (2013) Breast Cancer Res. Treat , vol.142 , pp. 45-57
    • Payne, K.K.1    Zoon, C.K.2    Wan, W.3    Marlar, K.4    Keim, R.C.5    Kenari, M.N.6    Kazim, A.L.7    Bear, H.D.8    Manjili, M.H.9
  • 11
    • 79960549766 scopus 로고    scopus 로고
    • Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse
    • Kmieciak, M.; Basu, D.; Payne, K.K.; Toor, A.; Yacoub, A.; Wang, X.Y.; Smith, L.; Bear, H.D.; Manjili, M.H. Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse. J. Immunol. 2011, 187, 708–717.
    • (2011) J. Immunol , vol.187 , pp. 708-717
    • Kmieciak, M.1    Basu, D.2    Payne, K.K.3    Toor, A.4    Yacoub, A.5    Wang, X.Y.6    Smith, L.7    Bear, H.D.8    Manjili, M.H.9
  • 12
    • 84873035870 scopus 로고    scopus 로고
    • Ex vivo expansion of tumor-reactive t cells by means of bryostatin 1/ionomycin and the common γ chain cytokines formulation
    • Kmieciak, M.; Toor, A.; Graham, L.; Bear, H.D.; Manjili, M.H. Ex vivo expansion of tumor-reactive t cells by means of bryostatin 1/ionomycin and the common γ chain cytokines formulation. J. Vis. Exp. 2011, 47, doi:10.3791/2381.
    • (2011) J. Vis. Exp , vol.47
    • Kmieciak, M.1    Toor, A.2    Graham, L.3    Bear, H.D.4    Manjili, M.H.5
  • 13
    • 78049379784 scopus 로고    scopus 로고
    • Phenotype, functions and fate of adoptively transferred tumor draining lymphocytes activated ex vivo in mice with an aggressive weakly immunogenic mammary carcinoma
    • Miller, C.H.; Graham, L.; Bear, H.D. Phenotype, functions and fate of adoptively transferred tumor draining lymphocytes activated ex vivo in mice with an aggressive weakly immunogenic mammary carcinoma. BMC Immunol. 2010, 11, doi:10.1186/1471-2172-11-54.
    • (2010) BMC Immunol , vol.11
    • Miller, C.H.1    Graham, L.2    Bear, H.D.3
  • 14
    • 77955658200 scopus 로고    scopus 로고
    • IL-7 + IL-15 are superior to IL-2 for the ex vivo expansion of 4T1 mammary carcinoma-specific T cells with greater efficacy against tumors in vivo
    • Cha, E.; Graham, L.; Manjili, M.H.; Bear, H.D. IL-7 + IL-15 are superior to IL-2 for the ex vivo expansion of 4T1 mammary carcinoma-specific T cells with greater efficacy against tumors in vivo. Breast Cancer Res. Treat. 2010, 122, 359–369.
    • (2010) Breast Cancer Res. Treat , vol.122 , pp. 359-369
    • Cha, E.1    Graham, L.2    Manjili, M.H.3    Bear, H.D.4
  • 15
    • 4544258659 scopus 로고    scopus 로고
    • Bryostatin 1/Ionomycin (B/I) ex vivo stimulation preferentially activates L-selectinlow tumor-sensitized lymphocytes
    • Chin, C.S.; Miller, C.H.; Graham, L.; Parviz, M.; Zacur, S.; Patel, B.; Duong, A.; Bear, H.D. Bryostatin 1/Ionomycin (B/I) ex vivo stimulation preferentially activates L-selectinlow tumor-sensitized lymphocytes. Int. Immunol. 2004, 16, 1283–1294.
    • (2004) Int. Immunol , vol.16 , pp. 1283-1294
    • Chin, C.S.1    Miller, C.H.2    Graham, L.3    Parviz, M.4    Zacur, S.5    Patel, B.6    Duong, A.7    Bear, H.D.8
  • 16
    • 0344513151 scopus 로고    scopus 로고
    • Successful adoptive immunotherapy with vaccine-sensitized T cells, despite no effect with vaccination alone in a weakly immunogenic tumor model
    • Parviz, M.; Chin, C.S.; Graham, L.J.; Miller, C.; Lee, C.; George, K.; Bear, H.D. Successful adoptive immunotherapy with vaccine-sensitized T cells, despite no effect with vaccination alone in a weakly immunogenic tumor model. Cancer Immunol. Immunother. 2003, 52, 739–750.
    • (2003) Cancer Immunol. Immunother , vol.52 , pp. 739-750
    • Parviz, M.1    Chin, C.S.2    Graham, L.J.3    Miller, C.4    Lee, C.5    George, K.6    Bear, H.D.7
  • 20
    • 42649134105 scopus 로고    scopus 로고
    • Interleukin-21: Basic biology and implications for cancer and autoimmunity
    • Spolski, R.; Leonard, W.J. Interleukin-21: basic biology and implications for cancer and autoimmunity. Annu. Rev. Immunol. 2008, 26, 57–79.
    • (2008) Annu. Rev. Immunol , vol.26 , pp. 57-79
    • Spolski, R.1    Leonard, W.J.2
  • 21
    • 25444434157 scopus 로고    scopus 로고
    • Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation
    • Leonard, W.J.; Spolski, R. Interleukin-21: A modulator of lymphoid proliferation, apoptosis and differentiation. Nat. Rev. Immunol. 2005, 5, 688–698.
    • (2005) Nat. Rev. Immunol , vol.5 , pp. 688-698
    • Leonard, W.J.1    Spolski, R.2
  • 23
    • 79956149133 scopus 로고    scopus 로고
    • Reprogramming CD19-Specific T Cells with IL-21 Signaling can improve adoptive immunotherapy of B-lineage malignancies
    • Singh, H.; Figliola, M.J.; Dawson, M.J.; Huls, H.; Olivares, S.; Switzer, K.; Mi, T.; Maiti, S.; Kebriaei, P.; Lee, D.A., et al. Reprogramming CD19-Specific T Cells with IL-21 Signaling can improve adoptive immunotherapy of B-lineage malignancies. Cancer Res. 2011, 71, 3516–3527.
    • (2011) Cancer Res , vol.71 , pp. 3516-3527
    • Singh, H.1    Figliola, M.J.2    Dawson, M.J.3    Huls, H.4    Olivares, S.5    Switzer, K.6    Mi, T.7    Maiti, S.8    Kebriaei, P.9    Lee, D.A.10
  • 27
    • 1642444178 scopus 로고    scopus 로고
    • IL-21 Induces tumor rejection by specific CTL and IFN-γ-dependent CXC Chemokines in Syngeneic Mice
    • Di Carlo, E.; Comes, A.; Orengo, A.M.; Rosso, O.; Meazza, R.; Musiani, P.; Colombo, M.P.; Ferrini, S. IL-21 Induces tumor rejection by specific CTL and IFN-γ-dependent CXC Chemokines in Syngeneic Mice. J. Immunol. 2004, 172, 1540–1547.
    • (2004) J. Immunol , vol.172 , pp. 1540-1547
    • Di Carlo, E.1    Comes, A.2    Orengo, A.M.3    Rosso, O.4    Meazza, R.5    Musiani, P.6    Colombo, M.P.7    Ferrini, S.8
  • 32
    • 18344394955 scopus 로고    scopus 로고
    • IL-21 limits NK Cell responses and promotes antigen-specific T cell activation: A mediator of the transition from innate to adaptive immunity
    • Kasaian, M.T.; Whitters, M.J.; Carter, L.L.; Lowe, L.D.; Jussif, J.M.; Deng, B.; Johnson, K.A.; Witek, J.S.; Senices, M.; Konz, R.F., et al. IL-21 limits NK Cell responses and promotes antigen-specific T cell activation: A mediator of the transition from innate to adaptive immunity. Immunity 2002, 16, 559–569.
    • (2002) Immunity , vol.16 , pp. 559-569
    • Kasaian, M.T.1    Whitters, M.J.2    Carter, L.L.3    Lowe, L.D.4    Jussif, J.M.5    Deng, B.6    Johnson, K.A.7    Witek, J.S.8    Senices, M.9    Konz, R.F.10
  • 33
    • 2542595794 scopus 로고    scopus 로고
    • IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: Comparative evaluation of IL-2, IL-15, and IL-21
    • Moroz, A.; Eppolito, C.; Li, Q.; Tao, J.; Clegg, C.H.; Shrikant, P.A. IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: Comparative evaluation of IL-2, IL-15, and IL-21. J. Immunol. 2004, 173, 900–909.
    • (2004) J. Immunol , vol.173 , pp. 900-909
    • Moroz, A.1    Eppolito, C.2    Li, Q.3    Tao, J.4    Clegg, C.H.5    Shrikant, P.A.6
  • 34
    • 23444445913 scopus 로고    scopus 로고
    • IL-21 Influences the frequency, phenotype, and affinity of the antigen-specific CD8 T cell response
    • Li, Y.; Bleakley, M.; Yee, C. IL-21 Influences the frequency, phenotype, and affinity of the antigen-specific CD8 T cell response. J. Immunol. 2005, 175, 2261–2269.
    • (2005) J. Immunol , vol.175 , pp. 2261-2269
    • Li, Y.1    Bleakley, M.2    Yee, C.3
  • 35
  • 36
    • 79251480771 scopus 로고    scopus 로고
    • IL-21-treated naive CD45RA+CD8+ T cells represent a reliable source for producing leukemia-reactive cytotoxic T lymphocytes with high proliferative potential and early differentiation phenotype. Cancer Immunol
    • Albrecht, J.; Frey, M.; Teschner, D.; Carbol, A.; Theobald, M.; Herr, W.; Distler, E. IL-21-treated naive CD45RA+CD8+ T cells represent a reliable source for producing leukemia-reactive cytotoxic T lymphocytes with high proliferative potential and early differentiation phenotype. Cancer Immunol. Immunother. 2011, 60, 235–248.
    • (2011) Immunother , vol.60 , pp. 235-248
    • Albrecht, J.1    Frey, M.2    Teschner, D.3    Carbol, A.4    Theobald, M.5    Herr, W.6    Distler, E.7
  • 37
    • 84866735170 scopus 로고    scopus 로고
    • Paths to stemness: Building the ultimate antitumour T cell
    • Gattinoni, L.; Klebanoff, C.A.; Restifo, N.P. Paths to stemness: Building the ultimate antitumour T cell. Nat. Rev. Cancer 2012, 12, 671–684.
    • (2012) Nat. Rev. Cancer , vol.12 , pp. 671-684
    • Gattinoni, L.1    Klebanoff, C.A.2    Restifo, N.P.3
  • 38
    • 0031154377 scopus 로고    scopus 로고
    • Sensitizing T-lymphocytes for adoptive immunotherapy by vaccination with wild-type or cytokine gene-transduced melanoma
    • Lipshy, K.A.; Kostuchenko, P.J.; Hamad, G.G.; Bland, C.E.; Barrett, S.K.; Bear, H.D. Sensitizing T-lymphocytes for adoptive immunotherapy by vaccination with wild-type or cytokine gene-transduced melanoma. Ann. Surg. Oncol. 1997, 4, 334–341.
    • (1997) Ann. Surg. Oncol , vol.4 , pp. 334-341
    • Lipshy, K.A.1    Kostuchenko, P.J.2    Hamad, G.G.3    Bland, C.E.4    Barrett, S.K.5    Bear, H.D.6
  • 40
    • 67049136157 scopus 로고    scopus 로고
    • Diversity in CD8+ T cell differentiation
    • Parish, I.A.; Kaech, S.M. Diversity in CD8+ T cell differentiation. Curr. Opin. Immunol. 2009, 21, 291–297.
    • (2009) Curr. Opin. Immunol , vol.21 , pp. 291-297
    • Parish, I.A.1    Kaech, S.M.2
  • 41
    • 75749134098 scopus 로고    scopus 로고
    • Memory CD8+ T cell differentiation
    • Obar, J.J.; Lefrancois, L. Memory CD8+ T cell differentiation. Ann. N. Y. Acad. Sci. 2010, 1183, 251–266.
    • (2010) Ann. N. Y. Acad. Sci , vol.1183 , pp. 251-266
    • Obar, J.J.1    Lefrancois, L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.