Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model

Annals of Neurology

Volumn 77, Issue 5, 2015, Pages 884-888

  Guo, Fuzheng ^a   Bannerman, Peter ^a   Mills Ko, Emily ^a   Miers, Laird ^a   Xu, Jie ^a   Burns, Travis ^a   Li, Shuo ^b   Freeman, Ernest ^b   McDonough, Jennifer A ^b   Pleasure, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b KENT STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; MYELIN; N ACETYLASPARTIC ACID; N ACETYLTRANSFERASE 8; UNCLASSIFIED DRUG; ASPARTIC ACID; N-ACETYLASPARTATE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; ATAXIA; CANAVAN DISEASE; CELL VACUOLE; CEREBELLUM; CONTROLLED STUDY; CORPUS CALLOSUM; FEMALE; FOREBRAIN; GENE DISRUPTION; GENE INACTIVATION; IMMUNOHISTOLOGY; LEUKODYSTROPHY; MALE; MOUSE; MYELINATION; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; PYRAMIDAL TRACT; REMYELINATING AXON; REMYELINIZATION; ROTAROD TEST; TONIC CLONIC SEIZURE; TRANSMISSION ELECTRON MICROSCOPY; WILD TYPE; ANALOGS AND DERIVATIVES; ANIMAL; DEFICIENCY; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; METABOLISM;

ANIMALS; ASPARTIC ACID; CANAVAN DISEASE; DISEASE MODELS, ANIMAL; FEMALE; MALE; MICE; MICE, KNOCKOUT;

EID: 84928137598     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.24392     Document Type: Article

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