-
1
-
-
84861988927
-
Structure-activity relationships for the binding of polymyxins with human alpha-1-acid glycoprotein
-
Azad MA, Huang JX, Cooper MA, Roberts KD, Thompson PE, Nation RL,. 2012. Structure-activity relationships for the binding of polymyxins with human alpha-1-acid glycoprotein. Biochem. Pharmacol. 84: 278-291.
-
(2012)
Biochem. Pharmacol.
, vol.84
, pp. 278-291
-
-
Azad, M.A.1
Huang, J.X.2
Cooper, M.A.3
Roberts, K.D.4
Thompson, P.E.5
Nation, R.L.6
-
2
-
-
0031416868
-
Coupling of ATP hydrolysis with channel gating by purified, reconstituted CFTR
-
Bear CE, Li C, Galley K, Wang Y, Garami E, Ramjeesingh M,. 1997. Coupling of ATP hydrolysis with channel gating by purified, reconstituted CFTR. J. Bioenerg. Biomembr. 29: 465-473.
-
(1997)
J. Bioenerg. Biomembr.
, vol.29
, pp. 465-473
-
-
Bear, C.E.1
Li, C.2
Galley, K.3
Wang, Y.4
Garami, E.5
Ramjeesingh, M.6
-
3
-
-
0034634370
-
Crystallographic analysis reveals common modes of binding of medium and long-chain fatty acids to human serum albumin
-
Bhattacharya AA, Grune T, Curry S,. 2000. Crystallographic analysis reveals common modes of binding of medium and long-chain fatty acids to human serum albumin. J. Mol. Biol. 303: 721-732.
-
(2000)
J. Mol. Biol.
, vol.303
, pp. 721-732
-
-
Bhattacharya, A.A.1
Grune, T.2
Curry, S.3
-
4
-
-
0036258208
-
Cystic fibrosis: A worldwide analysis of CFTR mutations - Correlation with incidence data and application to screening
-
Bobadilla JL, Macek M, Jr., Fine JP, Farrell PM,. 2002. Cystic fibrosis: a worldwide analysis of CFTR mutations - correlation with incidence data and application to screening. Hum. Mutat. 19: 575-606.
-
(2002)
Hum. Mutat.
, vol.19
, pp. 575-606
-
-
Bobadilla, J.L.1
Macek, Jr.M.2
Fine, J.P.3
Farrell, P.M.4
-
6
-
-
0029126026
-
An Investigation of the Use of Nile-Red as a Long-Wavelength Fluorescent-Probe for the Study of Alpha(1)-Acid Glycoprotein-Drug Interactions
-
Brown MB, Miller JN, Seare NJ,. 1995. An Investigation of the Use of Nile-Red as a Long-Wavelength Fluorescent-Probe for the Study of Alpha(1)-Acid Glycoprotein-Drug Interactions. J. Pharm. Biomed. Anal. 13: 1011-1017.
-
(1995)
J. Pharm. Biomed. Anal.
, vol.13
, pp. 1011-1017
-
-
Brown, M.B.1
Miller, J.N.2
Seare, N.J.3
-
8
-
-
47049125019
-
Molecular basis for the ATPase activity of CFTR
-
Cheung JC, Kim Chiaw P, Pasyk S, Bear CE,. 2008. Molecular basis for the ATPase activity of CFTR. Arch. Biochem. Biophys. 476: 95-100.
-
(2008)
Arch. Biochem. Biophys.
, vol.476
, pp. 95-100
-
-
Cheung, J.C.1
Kim Chiaw, P.2
Pasyk, S.3
Bear, C.E.4
-
9
-
-
0031683467
-
Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites
-
Curry S, Mandelkow H, Brick P, Franks N,. 1998. Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites. Nat. Struct. Biol. 5: 827-835.
-
(1998)
Nat. Struct. Biol.
, vol.5
, pp. 827-835
-
-
Curry, S.1
Mandelkow, H.2
Brick, P.3
Franks, N.4
-
10
-
-
0028220333
-
Heterogeneity in the severity of cystic fibrosis and the role of CFTR gene mutations
-
Dean M, Santis G,. 1994. Heterogeneity in the severity of cystic fibrosis and the role of CFTR gene mutations. Hum. Genet. 93: 364-368.
-
(1994)
Hum. Genet.
, vol.93
, pp. 364-368
-
-
Dean, M.1
Santis, G.2
-
11
-
-
0025190658
-
Significance of extravascular protein binding for antimicrobial pharmacodynamics in an in vitro capillary model of infection
-
Dudley MN, Blaser J, Gilbert D, Zinner SH,. 1990. Significance of extravascular protein binding for antimicrobial pharmacodynamics in an in vitro capillary model of infection. Antimicrob. Agents Chemother. 34: 98-101.
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 98-101
-
-
Dudley, M.N.1
Blaser, J.2
Gilbert, D.3
Zinner, S.H.4
-
12
-
-
0026321005
-
Variations in relative concentrations of variants of human alpha 1-acid glycoprotein after acute-phase conditions
-
Eap CB, Fischer JF, Baumann P,. 1991. Variations in relative concentrations of variants of human alpha 1-acid glycoprotein after acute-phase conditions. Clin. Chim. Acta 203: 379-385.
-
(1991)
Clin. Chim. Acta
, vol.203
, pp. 379-385
-
-
Eap, C.B.1
Fischer, J.F.2
Baumann, P.3
-
13
-
-
79953214409
-
Targeting the regulation of CFTR channels
-
Eckford PD, Bear CE,. 2011. Targeting the regulation of CFTR channels. Biochem. J. 435: e1-e4.
-
(2011)
Biochem. J.
, vol.435
, pp. e1-e4
-
-
Eckford, P.D.1
Bear, C.E.2
-
14
-
-
84868243529
-
Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner
-
Eckford PD, Li C, Ramjeesingh M, Bear CE,. 2012. Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator VX-770 (ivacaftor) opens the defective channel gate of mutant CFTR in a phosphorylation-dependent but ATP-independent manner. J. Biol. Chem. 287: 36639-36649.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 36639-36649
-
-
Eckford, P.D.1
Li, C.2
Ramjeesingh, M.3
Bear, C.E.4
-
15
-
-
84883797995
-
Fluorescent dye cocktail for multiplex drug-site mapping on human serum albumin
-
Er JC, Vendrell M, Tang MK, Zhai D, Chang YT,. 2013. Fluorescent dye cocktail for multiplex drug-site mapping on human serum albumin. ACS Comb. Sci. 15: 452-457.
-
(2013)
ACS Comb. Sci.
, vol.15
, pp. 452-457
-
-
Er, J.C.1
Vendrell, M.2
Tang, M.K.3
Zhai, D.4
Chang, Y.T.5
-
16
-
-
0025343040
-
Use of 1-anilino-8-naphthalene sulfonate as a fluorescent probe in the investigation of drug interactions with human alpha-1-acid glycoprotein and serum albumin
-
Essassi D, Zini R, Tillement JP,. 1990. Use of 1-anilino-8-naphthalene sulfonate as a fluorescent probe in the investigation of drug interactions with human alpha-1-acid glycoprotein and serum albumin. J. Pharm. Sci. 79: 9-13.
-
(1990)
J. Pharm. Sci.
, vol.79
, pp. 9-13
-
-
Essassi, D.1
Zini, R.2
Tillement, J.P.3
-
17
-
-
0034684227
-
Experimentally determined lipocalin structures
-
Flower DR,. 2000. Experimentally determined lipocalin structures. Biochim. Biophys. Acta 1482: 46-56.
-
(2000)
Biochim. Biophys. Acta
, vol.1482
, pp. 46-56
-
-
Flower, D.R.1
-
18
-
-
84865853894
-
Ivacaftor in subjects with cystic fibrosis who are homozygous for the F508del-CFTR mutation
-
Flume PA, Liou TG, Borowitz DS, Li H, Yen K, Ordonez CL,. 2012. Ivacaftor in subjects with cystic fibrosis who are homozygous for the F508del-CFTR mutation. Chest 142: 718-724.
-
(2012)
Chest
, vol.142
, pp. 718-724
-
-
Flume, P.A.1
Liou, T.G.2
Borowitz, D.S.3
Li, H.4
Yen, K.5
Ordonez, C.L.6
-
20
-
-
25144505772
-
Structural basis of the drug-binding specificity of human serum albumin
-
Ghuman J, Zunszain PA, Petitpas I, Bhattacharya AA, Otagiri M, Curry S,. 2005. Structural basis of the drug-binding specificity of human serum albumin. J. Mol. Biol. 353: 38-52.
-
(2005)
J. Mol. Biol.
, vol.353
, pp. 38-52
-
-
Ghuman, J.1
Zunszain, P.A.2
Petitpas, I.3
Bhattacharya, A.A.4
Otagiri, M.5
Curry, S.6
-
21
-
-
0019952227
-
Importance of protein binding for the interpretation of serum or plasma drug concentrations
-
Greenblatt DJ, Sellers EM, Koch-Weser J,. 1982. Importance of protein binding for the interpretation of serum or plasma drug concentrations. J. Clin. Pharmacol. 22: 259-263.
-
(1982)
J. Clin. Pharmacol.
, vol.22
, pp. 259-263
-
-
Greenblatt, D.J.1
Sellers, E.M.2
Koch-Weser, J.3
-
22
-
-
0026664548
-
Atomic structure and chemistry of human serum albumin
-
He XM, Carter DC,. 1992. Atomic structure and chemistry of human serum albumin. Nature 358: 209-215.
-
(1992)
Nature
, vol.358
, pp. 209-215
-
-
He, X.M.1
Carter, D.C.2
-
23
-
-
0031815338
-
Ligand specificity of the genetic variants of human α1-acid glycoprotein: Generation of a three-dimensional quantitative structure-activity relationship model for drug binding to the a variant
-
Hervé F, Caron G, Duché J-C, Gaillard P, Abd. Rahman N, Tsantili-Kakoulidou A,. 1998. Ligand specificity of the genetic variants of human α1-acid glycoprotein: generation of a three-dimensional quantitative structure-activity relationship model for drug binding to the a variant. Mol. Pharmacol. 54: 129-138.
-
(1998)
Mol. Pharmacol.
, vol.54
, pp. 129-138
-
-
Hervé, F.1
Caron, G.2
Duché, J.-C.3
Gaillard, P.4
Abd. Rahman, N.5
Tsantili-Kakoulidou, A.6
-
24
-
-
0027208098
-
Fractionation of the genetic variants of human alpha 1-acid glycoprotein in the native form by chromatography on an immobilized copper(II) affinity adsorbent. Heterogeneity of the separate variants by isoelectrofocusing and by concanavalin A affinity chromatography
-
Herve F, Gomas E, Duche JC, Tillement JP,. 1993. Fractionation of the genetic variants of human alpha 1-acid glycoprotein in the native form by chromatography on an immobilized copper(II) affinity adsorbent. Heterogeneity of the separate variants by isoelectrofocusing and by concanavalin A affinity chromatography. J. Chromatogr. 615: 47-57.
-
(1993)
J. Chromatogr.
, vol.615
, pp. 47-57
-
-
Herve, F.1
Gomas, E.2
Duche, J.C.3
Tillement, J.P.4
-
25
-
-
0037301226
-
Alpha(1)-acid glycoprotein: An acute phase protein with inflammatory and immunomodulating properties
-
Hochepied T, Berger FG, Baumann H, Libert C,. 2003. Alpha(1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties. Cytokine Growth Factor Rev. 14: 25-34.
-
(2003)
Cytokine Growth Factor Rev.
, vol.14
, pp. 25-34
-
-
Hochepied, T.1
Berger, F.G.2
Baumann, H.3
Libert, C.4
-
26
-
-
0034894719
-
Human alpha-1-glycoprotein and its interactions with drugs
-
Israili ZH, Dayton PG,. 2001. Human alpha-1-glycoprotein and its interactions with drugs. Drug Metab. Rev. 33: 161-235.
-
(2001)
Drug Metab. Rev.
, vol.33
, pp. 161-235
-
-
Israili, Z.H.1
Dayton, P.G.2
-
27
-
-
84875048537
-
Vx-770 potentiates CFTR function by promoting decoupling between the gating cycle and ATP hydrolysis cycle
-
Jih KY, Hwang TC,. 2013. Vx-770 potentiates CFTR function by promoting decoupling between the gating cycle and ATP hydrolysis cycle. Proc. Natl. Acad. Sci. U. S. A. 110: 4404-4409.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 4404-4409
-
-
Jih, K.Y.1
Hwang, T.C.2
-
28
-
-
0026536064
-
Fluorescence studies of beta-adrenergic ligand binding to alpha 1-acid glycoprotein with 1-anilino-8-naphthalene sulfonate, isoprenaline, adrenaline and propranolol
-
Johansen AK, Willassen NP, Sager G,. 1992. Fluorescence studies of beta-adrenergic ligand binding to alpha 1-acid glycoprotein with 1-anilino-8-naphthalene sulfonate, isoprenaline, adrenaline and propranolol. Biochem. Pharmacol. 43: 725-729.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 725-729
-
-
Johansen, A.K.1
Willassen, N.P.2
Sager, G.3
-
29
-
-
4744343547
-
A heteromeric complex of the two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) mediates ATPase activity
-
Kidd JF, Ramjeesingh M, Stratford F, Huan LJ, Bear CE,. 2004. A heteromeric complex of the two nucleotide binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) mediates ATPase activity. J. Biol. Chem. 279: 41664-41669.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41664-41669
-
-
Kidd, J.F.1
Ramjeesingh, M.2
Stratford, F.3
Huan, L.J.4
Bear, C.E.5
-
30
-
-
79953183131
-
Insights into the mechanisms underlying CFTR channel activity, the molecular basis for cystic fibrosis and strategies for therapy
-
Kim Chiaw P, Eckford PD, Bear CE,. 2011. Insights into the mechanisms underlying CFTR channel activity, the molecular basis for cystic fibrosis and strategies for therapy. Essays Biochem. 50: 233-248.
-
(2011)
Essays Biochem.
, vol.50
, pp. 233-248
-
-
Kim Chiaw, P.1
Eckford, P.D.2
Bear, C.E.3
-
31
-
-
0035853675
-
Perturbation of the pore of the cystic fibrosis transmembrane conductance regulator (CFTR) inhibits its atpase activity
-
Kogan I, Ramjeesingh M, Huan LJ, Wang Y, Bear CE,. 2001. Perturbation of the pore of the cystic fibrosis transmembrane conductance regulator (CFTR) inhibits its atpase activity. J. Biol. Chem. 276: 11575-11581.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11575-11581
-
-
Kogan, I.1
Ramjeesingh, M.2
Huan, L.J.3
Wang, Y.4
Bear, C.E.5
-
32
-
-
0036012501
-
Studies of the molecular basis for cystic fibrosis using purified reconstituted CFTR protein
-
Kogan I, Ramjeesingh M, Li C, Bear CE,. 2002. Studies of the molecular basis for cystic fibrosis using purified reconstituted CFTR protein. Methods Mol. Med. 70: 143-157.
-
(2002)
Methods Mol. Med.
, vol.70
, pp. 143-157
-
-
Kogan, I.1
Ramjeesingh, M.2
Li, C.3
Bear, C.E.4
-
33
-
-
0023690101
-
Drug binding to human alpha-1-acid glycoprotein in health and disease
-
Kremer JM, Wilting J, Janssen LH,. 1988. Drug binding to human alpha-1-acid glycoprotein in health and disease. Pharmacol. Rev. 40: 1-47.
-
(1988)
Pharmacol. Rev.
, vol.40
, pp. 1-47
-
-
Kremer, J.M.1
Wilting, J.2
Janssen, L.H.3
-
34
-
-
0021052764
-
Imipramine serum protein binding in healthy subjects
-
Kristensen CB,. 1983. Imipramine serum protein binding in healthy subjects. Clin. Pharmacol. Ther. 34: 689-694.
-
(1983)
Clin. Pharmacol. Ther.
, vol.34
, pp. 689-694
-
-
Kristensen, C.B.1
-
36
-
-
84928147509
-
The role of adherence, importance and burden from Cystic fibrosis etiology, diagnosis and treatments
-
Leatte P.N. (ed). Nova Biomedical: Hauppauge NY, USA.
-
Myers LB,. 2009. The role of adherence, importance and burden from Cystic fibrosis etiology, diagnosis and treatments. Treatments for Cystic fibrosis, Leatte PN, (ed). Nova Biomedical: Hauppauge NY, USA.
-
(2009)
Treatments for Cystic Fibrosis
-
-
Myers, L.B.1
-
37
-
-
79954585180
-
Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1S forms
-
Nishi K, Ono T, Nakamura T, Fukunaga N, Izumi M, Watanabe H,. 2011. Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1S forms. J. Biol. Chem. 286: 14427-14434.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 14427-14434
-
-
Nishi, K.1
Ono, T.2
Nakamura, T.3
Fukunaga, N.4
Izumi, M.5
Watanabe, H.6
-
38
-
-
33751555755
-
Identification of alpha-1 acid glycoprotein as a lysophospholipid binding protein: A complementary role to albumin in the scavenging of lysophosphatidylcholine
-
Ojala PJ, Hermansson M, Tolvanen M, Polvinen K, Hirvonen T, Impola U,. 2006. Identification of alpha-1 acid glycoprotein as a lysophospholipid binding protein: a complementary role to albumin in the scavenging of lysophosphatidylcholine. Biochemistry 45: 14021-14031.
-
(2006)
Biochemistry
, vol.45
, pp. 14021-14031
-
-
Ojala, P.J.1
Hermansson, M.2
Tolvanen, M.3
Polvinen, K.4
Hirvonen, T.5
Impola, U.6
-
39
-
-
33644687674
-
A molecular functional study on the interactions of drugs with plasma proteins
-
Otagiri M,. 2005. A molecular functional study on the interactions of drugs with plasma proteins. Drug Metab. Pharmacokinet. 20: 309-323.
-
(2005)
Drug Metab. Pharmacokinet.
, vol.20
, pp. 309-323
-
-
Otagiri, M.1
-
40
-
-
44449169949
-
The intact CFTR protein mediates ATPase rather than adenylate kinase activity
-
Ramjeesingh M, Ugwu F, Stratford FL, Huan LJ, Li C, Bear CE,. 2008. The intact CFTR protein mediates ATPase rather than adenylate kinase activity. Biochem. J. 412: 315-321.
-
(2008)
Biochem. J.
, vol.412
, pp. 315-321
-
-
Ramjeesingh, M.1
Ugwu, F.2
Stratford, F.L.3
Huan, L.J.4
Li, C.5
Bear, C.E.6
-
41
-
-
80455162465
-
A CFTR potentiator in patients with cystic fibrosis and the G551D mutation
-
Ramsey BW, Davies J, McElvaney NG, Tullis E, Bell SC, Drevinek P,. 2011. A CFTR potentiator in patients with cystic fibrosis and the G551D mutation. N. Engl. J. Med. 365: 1663-1672.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1663-1672
-
-
Ramsey, B.W.1
Davies, J.2
McElvaney, N.G.3
Tullis, E.4
Bell, S.C.5
Drevinek, P.6
-
42
-
-
84926083232
-
Antibacterial properties of the CFTR potentiator ivacaftor
-
Reznikov LR, Abou Alaiwa MH, McElvaney NG, Tullis E, Bell SC, Drevinek P,. 2014. Antibacterial properties of the CFTR potentiator ivacaftor. J. Cyst. Fibros. 13: 515-519.
-
(2014)
J. Cyst. Fibros.
, vol.13
, pp. 515-519
-
-
Reznikov, L.R.1
Abou Alaiwa, M.H.2
McElvaney, N.G.3
Tullis, E.4
Bell, S.C.5
Drevinek, P.6
-
43
-
-
79952446257
-
Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin
-
Ryan AJ, Ghuman J, Zunszain PA, Chung CW, Curry S,. 2013. Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin. J. Struct. Biol. 174: 84-91.
-
(2013)
J. Struct. Biol.
, vol.174
, pp. 84-91
-
-
Ryan, A.J.1
Ghuman, J.2
Zunszain, P.A.3
Chung, C.W.4
Curry, S.5
-
44
-
-
55849134825
-
Effect of protein binding on the pharmacological activity of highly bound antibiotics
-
Schmidt S, Rock K, Sahre M, Burkhardt O, Brunner M, Lobmeyer MT,. 2008. Effect of protein binding on the pharmacological activity of highly bound antibiotics. Antimicrob. Agents Chemother. 52: 3994-4000.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 3994-4000
-
-
Schmidt, S.1
Rock, K.2
Sahre, M.3
Burkhardt, O.4
Brunner, M.5
Lobmeyer, M.T.6
-
45
-
-
54949158207
-
The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin
-
Schonfeld DL, Ravelli RB, Mueller U, Skerra A,. 2008. The 1.8-A crystal structure of alpha1-acid glycoprotein (Orosomucoid) solved by UV RIP reveals the broad drug-binding activity of this human plasma lipocalin. J. Mol. Biol. 384: 393-405.
-
(2008)
J. Mol. Biol.
, vol.384
, pp. 393-405
-
-
Schonfeld, D.L.1
Ravelli, R.B.2
Mueller, U.3
Skerra, A.4
-
46
-
-
0034684235
-
Lipocalins as a scaffold
-
Skerra A,. 2000. Lipocalins as a scaffold. Biochim. Biophys. Acta 1482: 337-350.
-
(2000)
Biochim. Biophys. Acta
, vol.1482
, pp. 337-350
-
-
Skerra, A.1
-
47
-
-
0029114623
-
Treatment of cystic fibrosis based on understanding CFTR
-
Smith AE,. 1995. Treatment of cystic fibrosis based on understanding CFTR. J. Inherit. Metab. Dis. 18: 508-516.
-
(1995)
J. Inherit. Metab. Dis.
, vol.18
, pp. 508-516
-
-
Smith, A.E.1
-
48
-
-
84928147508
-
Cystic fibrosis-update on diagnosis and treatment from Cystic fibrosis etiology, diagnosisn and treatments
-
Leatte P.N. (ed). Nova Biomedical: Hauppauge NY, USA.
-
Solomon M,. 2009. Cystic fibrosis-update on diagnosis and treatment from Cystic fibrosis etiology, diagnosisn and treatments. Treatments for Cystic fibrosis, Leatte PN, (ed). Nova Biomedical: Hauppauge NY, USA.
-
(2009)
Treatments for Cystic Fibrosis
-
-
Solomon, M.1
-
49
-
-
0016801988
-
The characterization of two specific drug binding sites on human serum albumin
-
Sudlow G, Birkett DJ, Wade DN,. 1975. The characterization of two specific drug binding sites on human serum albumin. Mol. Pharmacol. 11: 824-832.
-
(1975)
Mol. Pharmacol.
, vol.11
, pp. 824-832
-
-
Sudlow, G.1
Birkett, D.J.2
Wade, D.N.3
-
50
-
-
0017174391
-
Further characterization of specific drug binding sites on human serum albumin
-
Sudlow G, Birkett DJ, Wade DN,. 1976. Further characterization of specific drug binding sites on human serum albumin. Mol. Pharmacol. 12: 1052-1061.
-
(1976)
Mol. Pharmacol.
, vol.12
, pp. 1052-1061
-
-
Sudlow, G.1
Birkett, D.J.2
Wade, D.N.3
-
51
-
-
0021994490
-
Auramine O as a fluorescent probe for the binding of basic drugs to human alpha 1-acid glycoprotein (alpha 1-AG). The development of a simple fluorometric method for the determination of alpha 1-AG in human serum
-
Sugiyama Y, Suzuki Y, Sawada Y, Kawasaki S, Beppu T, Iga T,. 1985. Auramine O as a fluorescent probe for the binding of basic drugs to human alpha 1-acid glycoprotein (alpha 1-AG). The development of a simple fluorometric method for the determination of alpha 1-AG in human serum. Biochem. Pharmacol. 34: 821-829.
-
(1985)
Biochem. Pharmacol.
, vol.34
, pp. 821-829
-
-
Sugiyama, Y.1
Suzuki, Y.2
Sawada, Y.3
Kawasaki, S.4
Beppu, T.5
Iga, T.6
-
52
-
-
0029160442
-
CFTR expression and organ damage in cystic fibrosis
-
Tizzano EF, Buchwald M,. 1995. CFTR expression and organ damage in cystic fibrosis. Ann. Intern. Med. 123: 305-308.
-
(1995)
Ann. Intern. Med.
, vol.123
, pp. 305-308
-
-
Tizzano, E.F.1
Buchwald, M.2
-
53
-
-
0027034365
-
Mutations and sequence variations detected in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: A report from the Cystic Fibrosis Genetic Analysis Consortium
-
Tsui LC,. 1992. Mutations and sequence variations detected in the cystic fibrosis transmembrane conductance regulator (CFTR) gene: a report from the Cystic Fibrosis Genetic Analysis Consortium. Hum. Mutat. 1: 197-203.
-
(1992)
Hum. Mutat.
, vol.1
, pp. 197-203
-
-
Tsui, L.C.1
-
54
-
-
73249114731
-
Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770
-
Van Goor F, Hadida S, Grootenhuis PD, Burton B, Cao D, Neuberger T,. 2009. Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770. Proc. Natl. Acad. Sci. U. S. A. 106: 18825-18830.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 18825-18830
-
-
Van Goor, F.1
Hadida, S.2
Grootenhuis, P.D.3
Burton, B.4
Cao, D.5
Neuberger, T.6
-
55
-
-
0041919542
-
Improved protein-ligand docking using GOLD
-
Verdonk ML, Cole JC, Hartshorn MJ, Murray CW, Taylor RD,. 2003. Improved protein-ligand docking using GOLD. Proteins 52: 609-623.
-
(2003)
Proteins
, vol.52
, pp. 609-623
-
-
Verdonk, M.L.1
Cole, J.C.2
Hartshorn, M.J.3
Murray, C.W.4
Taylor, R.D.5
-
56
-
-
0019984864
-
Serum levels of acute phase and cardiac proteins after myocardial infarction, surgery, and infection
-
Voulgari F, Cummins P, Gardecki TI, Beeching NJ, Stone PC, Stuart J,. 1982. Serum levels of acute phase and cardiac proteins after myocardial infarction, surgery, and infection. Br. Heart J. 48: 352-356.
-
(1982)
Br. Heart J.
, vol.48
, pp. 352-356
-
-
Voulgari, F.1
Cummins, P.2
Gardecki, T.I.3
Beeching, N.J.4
Stone, P.C.5
Stuart, J.6
-
57
-
-
0027162649
-
Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
-
Welsh MJ, Smith AE,. 1993. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73: 1251-1254.
-
(1993)
Cell
, vol.73
, pp. 1251-1254
-
-
Welsh, M.J.1
Smith, A.E.2
-
59
-
-
0025948426
-
Cystic fibrosis, the CFTR, and rectifying Cl- channels
-
discussion 269-272.
-
Wine JJ, Brayden DJ, Hagiwara G, Krouse ME, Law TC, Muller UJ,. 1991. Cystic fibrosis, the CFTR, and rectifying Cl- channels. Adv. Exp. Med. Biol. 290: 253-269; discussion 269-272.
-
(1991)
Adv. Exp. Med. Biol.
, vol.290
, pp. 253-269
-
-
Wine, J.J.1
Brayden, D.J.2
Hagiwara, G.3
Krouse, M.E.4
Law, T.C.5
Muller, U.J.6
-
60
-
-
0021875614
-
The relevance of pharmacokinetics to in-vitro models: Protein binding - Does it matter?
-
Suppl A.
-
Wise R,. 1985. The relevance of pharmacokinetics to in-vitro models: protein binding - does it matter? J. Antimicrob. Chemother. 15: 77-83. Suppl A.
-
(1985)
J. Antimicrob. Chemother.
, vol.15
, pp. 77-83
-
-
Wise, R.1
-
61
-
-
0023013936
-
The clinical relevance of protein binding and tissue concentrations in antimicrobial therapy
-
Wise R,. 1986. The clinical relevance of protein binding and tissue concentrations in antimicrobial therapy. Clin. Pharmacokinet. 11: 470-482.
-
(1986)
Clin. Pharmacokinet.
, vol.11
, pp. 470-482
-
-
Wise, R.1
-
62
-
-
44749084521
-
Biliverdin is the endogenous ligand of human serum alpha(1)-acid glycoprotein
-
Zsila F, Mady G,. 2008. Biliverdin is the endogenous ligand of human serum alpha(1)-acid glycoprotein. Biochem. Biophys. Res. Commun. 372: 503-507.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.372
, pp. 503-507
-
-
Zsila, F.1
Mady, G.2
|