Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations

Nature Communications

Volumn 6, Issue , 2015, Pages

  Huang, Lv Zhen ^a,b,c   Li, Ying Jie ^d   Xie, Xue Feng ^e   Zhang, Jing Jing ^a,b,c   Cheng, Ching Yu ^f,g,h,i   Yamashiro, Kenji ^j   Chen, Li Jia ^k   Ma, Xiao Yun ^l   Cheung, Chui Ming G ^f,i   Wang, Yu Sheng ^i,m   Zhang, Chun Fang ^b   Bai, Yu Jing ^a,b,c   Hou, Jing ^a,b,c   Chen, Xiao Li ^a,b,c   Qi, Yun ^a,b,c   Li, Shan Shan ^a,b,c   Sun, Yao Yao ^a,b,c   Mei, Jun Pu ^e   Cheng, Yong ^a,b,c   Yu, Wen Zhen ^a,b,c   Hu, Xiong Bing ⁿ   Zhuang, Feng Feng ⁿ   Fan, Lei ^o   Lu, Yi ^o,p   Sun, Xing Huai ^o,p   Zhu, Xiang Jia ^o,p   Shen, De Fen ^q   Chan, Chi Chao ^q   Zhao, Ming Wei ^a,b,c   Yoshimura, Nagahisa ^j   Pang, Chi Pui ^k   Wong, Tien Yin ^f,g,h,i   Khor, Chiea Chuen ^a,h,r   Zhang, Kang ^s,t   Zhou, Peng ^n,o,p   Li, Xiao Xin ^a,b,c   more..

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^c Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases   (China)

^d CANCER HOSPITAL   (China)

^e BGI SHENZHEN   (China)

^f SINGAPORE EYE RESEARCH INSTITUTE   (Singapore)

^g DUKE NUS MEDICAL SCHOOL   (Singapore)

^h NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

ⁱ SINGAPORE NATIONAL EYE CENTRE   (Singapore)

^j KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^k CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^l Guanghua Hospital of Integrative Medicine   (China)

^m FOURTH MILITARY MEDICAL UNIVERSITY   (China)

ⁿ Department of Clinical Epidemiology Peking University People's Hospital ^*  (China)

^o FUDAN UNIVERSITY   (China)

^p FUDAN UNIVERSITY   (China)

^q NATIONAL EYE INSTITUTE   (United States)

^r GENOME INSTITUTE OF SINGAPORE   (Singapore)

^s UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^t UNIVERSITY OF CALIFORNIA   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE E3D; UNCLASSIFIED DRUG; COLORING AGENT; INDOCYANINE GREEN; UBE3D PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

AMINO ACID; BLINDNESS; ELDERLY POPULATION; GENE EXPRESSION; PATHOGENICITY; PIGMENT; PROTEIN;

AGE RELATED MACULAR DEGENERATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; EAST ASIAN; ELECTRORETINOGRAPHY; FEMALE; FOLLOW UP; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MICROVILLUS; MISSENSE MUTATION; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PIGMENT GRANULE; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; WHOLE EXOME SEQUENCING; AGED; ANGIOGRAPHY; ANIMAL; ASIAN CONTINENTAL ANCESTRY GROUP; CASE CONTROL STUDY; CHINA; DNA SEQUENCE; EXOME; GENETIC PREDISPOSITION; GENETICS; HONG KONG; JAPAN; KNOCKOUT MOUSE; MACULAR DEGENERATION; MALE; MIDDLE AGED; OPTICAL COHERENCE TOMOGRAPHY; PATHOLOGY; RETINAL PIGMENT EPITHELIUM; SINGAPORE;

FAR EAST;

MUS;

AGED; ANGIOGRAPHY; ANIMALS; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; COLORING AGENTS; ELECTRORETINOGRAPHY; EXOME; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HONG KONG; HUMANS; INDOCYANINE GREEN; JAPAN; MACULAR DEGENERATION; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RETINAL PIGMENT EPITHELIUM; SEQUENCE ANALYSIS, DNA; SINGAPORE; TOMOGRAPHY, OPTICAL COHERENCE; UBIQUITIN-PROTEIN LIGASES;

EID: 84928104964     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7687     Document Type: Article

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