Treatment of maternal depression in a medication clinical trial and its effect on children

American Journal of Psychiatry

Volumn 172, Issue 5, 2015, Pages 450-459

  Weissman, Myrna M ^a   Wickramaratne, Priya ^a   Pilowsky, Daniel J ^a   Poh, Ernest ^a   Batten, Lisa A ^a   Hernandez, Mariely ^a   Flament, Martine F ^a   Stewart, Jessica A ^a   McGrath, Patrick ^a   Blier, Pierre ^a   Stewart, Jonathan W ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; ESCITALOPRAM; ANTIDEPRESSANT AGENT; CITALOPRAM;

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISTRESS SYNDROME; DOUBLE BLIND PROCEDURE; DSM-5; FEMALE; HAMILTON DEPRESSION RATING SCALE; HUMAN; IRRITABILITY; MAJOR CLINICAL STUDY; MATERNAL CARE; MENTAL DISEASE; MONOTHERAPY; MONTGOMERY ASBERG DEPRESSION RATING SCALE; MOTHER CHILD RELATION; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PSYCHOTHERAPY; PUERPERAL DEPRESSION; RANDOMIZED CONTROLLED TRIAL; REMISSION; SCHOOL CHILD; SOCIAL ADAPTATION; STRUCTURED INTERVIEW; SYMPTOMATOLOGY; DEPRESSION; DRUG COMBINATION; MALE; MOTHER; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; TREATMENT OUTCOME;

ADULT; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BUPROPION; CHILD; CHILD OF IMPAIRED PARENTS; CITALOPRAM; DEPRESSION; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; MALE; MOTHER-CHILD RELATIONS; MOTHERS; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME;

EID: 84928030196     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2014.13121679     Document Type: Article

References (37)

1. Beardslee WR, Gladstone TR, O'Connor EE: Transmission and prevention of mood disorders among children of affectively ill parents: a review. J Am Acad Child Adolesc Psychiatry 2011; 50: 1098-1109
2. Batten LA, Hernandez M, Pilowsky DJ, et al: Children of treatment-seeking depressed mothers: a comparison with the Sequenced Treatment Alternatives to Relieve Depression (STAR∗D) child study. J Am Acad Child Adolesc Psychiatry 2012; 51:1185-1196
3. Hammen C, Burge D, Burney E, et al: Longitudinal study of diagnoses in children of women with unipolar and bipolar affective disorder. Arch Gen Psychiatry 1990; 47:1112-1117
4. Pilowsky DJ, Wickramaratne PJ, Rush AJ, et al: Children of currently depressed mothers: a STAR∗D ancillary study. J Clin Psychiatry 2006; 67:126-136
5. Weissman MM, Feder A, Pilowsky DJ, et al: Depressed mothers coming to primary care: maternal reports of problems with their children. J Affect Disord 2004; 78:93-100
6. Weissman MM, Wickramaratne P, Nomura Y, et al: Families at high and low risk for depression: a 3-generation study. Arch Gen Psychiatry 2005; 62:29-36
7. Barker ED, Copeland W, Maughan B, et al: Relative impact of maternal depression and associated risk factors on offspring psychopathology. Br J Psychiatry 2012; 200:124-129
8. Weissman MM, Pilowsky DJ, Wickramaratne PJ, et al: Remissions in maternal depression and child psychopathology: a STAR∗D-Child report. JAMA 2006; 295:1389-1398
9. Pilowsky DJ, Wickramaratne P, Talati A, et al: Children of depressed mothers 1 year after the initiation of maternal treatment: findings from the STAR∗D-Child Study. Am J Psychiatry 2008; 165:1136-1147
10. Wickramaratne P, Gameroff MJ, Pilowsky DJ, et al: Children of depressed mothers 1 year after remissionofmaternal depression: findings from the STAR∗D-Child study. Am J Psychiatry 2011; 168:593-602
11. Garber J, Ciesla JA, McCauley E, et al: Remission of depression in parents: links to healthy functioning in their children. Child Dev 2011; 82:226-243
12. Swartz HA, Frank E, Zuckoff A, et al: Brief interpersonal psychotherapy for depressed mothers whose children are receiving psychiatric treatment. Am J Psychiatry 2008; 165:1155-1162
13. Coiro MJ, Riley A, Broitman M, et al: Effects on children of treating their mothers' depression: results of a 12-month follow-up. Psychiatr Serv 2012; 63:357-363
14. Verduyn C, Barrowclough C, Roberts J, et al: Maternal depression and child behaviour problems: randomised placebo-controlled trial of a cognitive-behavioural group intervention. Br J Psychiatry 2003; 183:342-348
15. Stewart JW, McGrath PJ, Blondeau C, et al: Combination antidepressant therapy for major depressive disorder: speed and probability of remission. J Psychiatr Res 2014; 52:7-14
16. First MB, Spitzer RL, Gibbon M, et al: Structured Clinical Interview for DSM-IV Axis I Disorders, Patient Edition (SCID-P). New York, New York State Psychiatric Institute, Biometrics Research, 1995
17. Hamilton M: Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6:278-296
18. Endicott J, Cohen J, Nee J, et al: Hamilton Depression Rating Scale: extracted from regular and change versions of the Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 1981; 38:98-103
19. Rush AJ, Trivedi MH, Ibrahim HM, et al: The 16-item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression. Biol Psychiatry 2003; 54: 573-583
20. Montgomery SA, Åsberg M: A new depression scale designed to be sensitive to change. Br J Psychiatry 1979; 134:382-389
21. Weissman MM, Prusoff BA, Thompson WD, et al: Social adjustment by self-report in a community sample and in psychiatric outpatients. J Nerv Ment Dis 1978; 166:317-326
22. Gameroff MJ, Wickramaratne P, Weissman MM: Testing the short and screener versions of the Social Adjustment Scale-Self-Report (SAS-SR). Int J Methods Psychiatr Res 2012; 21:52-65
23. Nutt D, Demyttenaere K, Janka Z, et al: The other face of depression, reduced positive affect: the role of catecholamines in causation and cure. J Psychopharmacol 2007; 21:461-471
24. Stahl SM, Pradko JF, Haight BR, et al: A review of the neuropharmacologyofbupropion, adualnorepinephrine anddopamine reuptake inhibitor. Prim Care Companion J Clin Psychiatry 2004; 6:159-166
25. Gerra ML, Marchesi C, Amat JA, et al: Does negative affectivity predict differential response to an SSRI versus a non-SSRI antidepressant?J Clin Psychiatry 2014; 75:e939-e944
26. Kaufman J, Birmaher B, Brent D, et al: Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 1997; 36:980-988
27. Kovacs M: The Children's Depression Inventory Manual. Toronto, Multi-Health Systems, 1992
28. nd ed. Edited by Rush AJ, First MB, Blacker D. Washington, DC, American Psychiatric Publishing, 2008, pp 333-335
29. Bird HR, Shaffer D, Fisher P, et al: The Columbia Impairment Scale (CIS): pilot findings on a measure of global impairment for children and adolescents. Int J Methods Psychiatr Res 1993; 3:167-176
30. Parker G, Tupling H, Brown LB: Aparental bonding instrument. Br J Med Psychol 1979; 52:1-10
31. Liang KY, Zeger SL: Longitudinal data analysis using generalized linear models. Biometrika 1986; 73:13-22
32. Singer JD: Using SAS PROC mixed to fit multilevel models, hierarchical models, and individual growth models. J Educ Behav Stat 1998; 29:323-355
33. Weiss RE: Modeling Longitudinal Data. New York, Springer, 2005
34. nd ed. Hoboken, NJ, John Wiley & Sons, 2012
35. Papakostas GI, Stahl SM, Krishen A, et al: Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of major depressive disorder with high levels of anxiety (anxious depression): a pooled analysis of 10 studies. J Clin Psychiatry 2008; 69:1287-1292
36. Papakostas GI, Trivedi MH, Alpert JE, et al: Efficacy of bupropion and the selective serotonin reuptake inhibitors in the treatment of anxiety symptoms in major depressive disorder: a meta-analysis of individual patient data from 10 double-blind, randomized clinical trials. J Psychiatr Res 2008; 42:134-140
37. Cohen RM, Greenberg JM, IsHak WW: Incorporating multidimensional patient-reported outcomes of symptom severity, functioning, and quality of life in the Individual Burden of Illness Index for Depression to measure treatment impact and recovery in MDD. JAMA Psychiatry 2013; 70:343-350