A fungal protease allergen provokes airway hyper-responsiveness in asthma

Nature Communications

Volumn 6, Issue , 2015, Pages

  Balenga, Nariman A ^a,d   Klichinsky, Michael ^b   Xie, Zhihui ^a   Chan, Eunice C ^a   Zhao, Ming ^a   Jude, Joseph ^b   Laviolette, Michel ^c   Panettieri, Reynold A ^b   Druey, Kirk M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c LAVAL UNIVERSITY   (Canada)

^d UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PROTEASE 1; ALKALINE PROTEINASE; ASP F13 ALLERGEN; CALCIUM ION; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 3; CONTRACTILE PROTEIN; FIBRONECTIN; FUNGAL ENZYME; FUNGUS ANTIGEN; G PROTEIN COUPLED RECEPTOR; INTEGRIN; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SERINE PROTEINASE; STROMELYSIN; TISSUE INHIBITOR OF METALLOPROTEINASE; UNCLASSIFIED DRUG; VINCULIN; ALLERGEN; BACTERIAL PROTEIN; CALCIUM; FUNGAL PROTEIN; HISTAMINE; IMMUNOGLOBULIN E; PROTEINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, MOUSE;

ALLERGY; ASTHMA; BIODEGRADATION; DISEASE TREATMENT; ENERGY EFFICIENCY; ENZYME ACTIVITY; FUNGAL DISEASE; FUNGUS; INFILTRATION; ORGANIC COMPOUND; PATHOGEN; PHYSIOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPERGILLUS FUMIGATUS; ASTHMA; AUTOPHOSPHORYLATION; BRONCHOCONSTRICTION; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL COUNT; CELL ELONGATION; CELL INTERACTION; CELL PROLIFERATION; CELL STIMULATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEGRADATION; DESQUAMATION; EC50; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; EXTRACELLULAR MATRIX; FEMALE; FORCED EXPIRATORY VOLUME; IN VITRO STUDY; IN VIVO STUDY; LUNG DISEASE; LUNG INFILTRATE; LUNG RESISTANCE; METAPLASIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; SENSITIZATION; SMOOTH MUSCLE CONTRACTION; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; BRONCHUS; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; PATHOLOGY; PRIMARY CELL CULTURE; SMOOTH MUSCLE CELL; TRACHEA;

ASPERGILLUS FUMIGATUS; FUNGI;

ADMINISTRATION, INHALATION; ALLERGENS; ANIMALS; ASPERGILLUS FUMIGATUS; ASTHMA; BACTERIAL PROTEINS; BRONCHI; BRONCHOCONSTRICTION; CALCIUM; DISEASE MODELS, ANIMAL; ENDOPEPTIDASES; EXTRACELLULAR MATRIX; FEMALE; FUNGAL PROTEINS; GENE EXPRESSION; HISTAMINE; HUMANS; IMMUNOGLOBULIN E; MICE; MICE, INBRED BALB C; MYOCYTES, SMOOTH MUSCLE; PRIMARY CELL CULTURE; RHO GTP-BINDING PROTEINS; TRACHEA;

EID: 84927941703     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7763     Document Type: Article

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