Identification and characterization of novel serum microRNAs in unstable angina pectoris and subclinical atherosclerotic patients

Experimental Cell Research

Volumn 333, Issue 2, 2015, Pages 220-227

  Sun, Qiyu ^a,b   Jia, Xingwang ^a   Gao, Jing ^a   Zhang, Pengjun ^a   Mou, Wenjun ^a   Yang, Caie ^a   Tong, Hongli ^a   Wen, Xinyu ^a   Tian, Yaping ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b CHENGDE MEDICAL COLLEGE   (China)

Author keywords

Atherosclerosis; MicroRNA; Solexa; Unstable angina pectoris

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; MICRORNA; MICRORNA N1; MICRORNA N2; MICRORNA N3; UNCLASSIFIED DRUG;

ARTICLE; BIOINFORMATICS; BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DIAGNOSTIC TEST ACCURACY STUDY; DIFFERENTIAL DIAGNOSIS; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MICRORNA N1 BLOOD LEVEL; MICRORNA N2 BLOOD LEVEL; MICRORNA N3 BLOOD LEVEL; PREDICTION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SERUM; SOLEXA SEQUENCING; UNSTABLE ANGINA PECTORIS; VALIDATION STUDY; ATHEROSCLEROSIS; BLOOD; CASE CONTROL STUDY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RECEIVER OPERATING CHARACTERISTIC;

ANGINA, UNSTABLE; ATHEROSCLEROSIS; BASE SEQUENCE; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; HUMANS; MICRORNAS; MOLECULAR SEQUENCE DATA; ROC CURVE;

EID: 84927912309     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2015.01.005     Document Type: Article

References (50)

1. Wachira J.K., Stys T.P. Cardiovascular disease and bridging the diagnostic gap. South Dak. Med.: J. South Dak. State Med. Assoc. 2013, 66:366-369.
2. miRBase. http://www.mirbase.org/index.shtml.
3. Frostegard J. Immunity, atherosclerosis and cardiovascular disease. BMC Med. 2013, 11:117.
4. Raitoharju E., Oksala N., Lehtimaki T. MicroRNAs in the atherosclerotic plaque. Clin. Chem. 2013, 59:1708-1721.
5. Seneviratne A., Hulsmans M., Holvoet P., Monaco C. Biomechanical factors and macrophages in plaque stability. Cardiovasc. Res. 2013, 99:284-293.
6. Landgraf P., Rusu M., Sheridan R., Sewer A., Iovino N., Aravin A., Pfeffer S., Rice A., Kamphorst A.O., Landthaler M., Lin C., Socci N.D., Hermida L., Fulci V., Chiaretti S., Foa R., Schliwka J., Fuchs U., Novosel A., Muller R.U., Schermer B., Bissels U., Inman J., Phan Q., Chien M., Weir D.B., Choksi R., De Vita G., Frezzetti D., Trompeter H.I., Hornung V., Teng G., Hartmann G., Palkovits M., Di Lauro R., Wernet P., Macino G., Rogler C.E., Nagle J.W., Ju J., Papavasiliou F.N., Benzing T., Lichter P., Tam W., Brownstein M.J., Bosio A., Borkhardt A., Russo J.J., Sander C., Zavolan M., Tuschl T. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007, 129:1401-1414.
7. Small E.M., Olson E.N. Pervasive roles of microRNAs in cardiovascular biology. Nature 2011, 469:336-342.
8. Madrigal-Matute J., Rotllan N., Aranda J.F., Fernandez-Hernando C. MicroRNAs and atherosclerosis. Curr. Atheroscler. Rep. 2013, 15:322.
9. Guo M., Mao X., Ji Q., Lang M., Li S., Peng Y., Zhou W., Xiong B., Zeng Q. miR-146a in PBMCs modulates Th1 function in patients with acute coronary syndrome. Immunol. Cell Biol. 2010, 88:555-564.
10. Chen X., Liang H., Zhang J., Zen K., Zhang C.Y. Secreted microRNAs: a new form of intercellular communication. Trends Cell Biol. 2012, 22:125-132.
11. Creemers E.E., Tijsen A.J., Pinto Y.M. Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?. Circ. Res. 2012, 110:483-495.
12. Fichtlscherer S., De Rosa S., Fox H., Schwietz T., Fischer A., Liebetrau C., Weber M., Hamm C.W., Roxe T., Muller-Ardogan M., Bonauer A., Zeiher A.M., Dimmeler S. Circulating microRNAs in patients with coronary artery disease. Circ. Res. 2010, 107:677-684.
13. Zhu N., Zhang D., Chen S., Liu X., Lin L., Huang X., Guo Z., Liu J., Wang Y., Yuan W., Qin Y. Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration. Atherosclerosis 2011, 215:286-293.
14. Harris T.A., Yamakuchi M., Ferlito M., Mendell J.T., Lowenstein C.J. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc. Natl. Acad. Sci. USA 2008, 105:1516-1521.
15. Lovren F., Pan Y., Quan A., Singh K.K., Shukla P.C., Gupta N., Steer B.M., Ingram A.J., Gupta M., Al-Omran M., Teoh H., Marsden P.A., Verma S. MicroRNA-145 targeted therapy reduces atherosclerosis. Circulation 2012, 126:S81-90.
16. Olivieri F., Antonicelli R., Lorenzi M., D'Alessandra Y., Lazzarini R., Santini G., Spazzafumo L., Lisa R., La Sala L., Galeazzi R., Recchioni R., Testa R., Pompilio G., Capogrossi M.C., Procopio A.D. Diagnostic potential of circulating miR-499-5p in elderly patients with acute non ST-elevation myocardial infarction. Int. J. Cardiol. 2013, 167:531-536.
17. Bostjancic E., Zidar N., Stajer D., Glavac D. MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarction. Cardiology 2010, 115:163-169.
18. Olof G., Patrik A., van der Jesper P., Matthias G., David E. Cardio specific microRNA plasma levels correlate with troponin and cardiac function in patients with ST elevation myocardial infarction, are selectively dependent on renal elimination, and can be detected in urine samples. Cardiology 2011, 118:217-226.
19. Wang G.K., Zhu J.Q., Zhang J.T., Li Q., Li Y., He J., Qin Y.W., Jing Q. Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur. Heart J. 2010, 31:659-666.
20. Corsten M.F., Dennert R., Jochems S., Kuznetsova T., Devaux Y., Hofstra L., Wagner D.R., Staessen J.A., Heymans S., Schroen B. Circulating microRNA-208b and microRNA-499 reflect myocardial damage in cardiovascular disease. Circ.-cardiovascular Genet. 2010, 3:499-506.
21. Ai J., Zhang R., Li Y., Pu J., Lu Y., Jiao J., Li K., Yu B., Li Z., Wang R., Wang L., Li Q., Wang N., Shan H., Li Z., Yang B. Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction. Biochem. Biophys. Res. Commun. 2010, 391:73-77.
22. Lippi G., Mattiuzzi C., Cervellin G. Circulating microRNAs (miRs) for diagnosing acute myocardial infarction: meta-analysis of available studies. Int. J. Cardiol. 2013, 167:277-278.
23. Hafner M., Landgraf P., Ludwig J., Rice A., Ojo T., Lin C., Holoch D., Lim C., Tuschl T. Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods 2008, 44:3Y12.
24. Song Y., Li L., Ou Y., Gao Z., Li E., Li X., et al. Identification of genomic alterations in oesophageal squamous cell cancer. Nature 2014, 509:91-95.
25. Li C., Fang Z., Jiang T., Zhang Q., Liu C., Zhang Q., Zhang C., Xiang Y. Serum microRNAs profile from genome-wide serves as a fingerprint for diagnosis of acute myocardial infarction and angina pectoris. BMC Med. Genomics 2013, 6:16. (PMID: 23641832) http://www.ncbi.nlm.nih.gov/pubmed/.
26. Wang H.J., Zhang P.J., Chen W.J., Jie D., Dan F., Jia Y.H., Xie L.X. Characterization and Identification of novel serum microRNAs in sepsis patients with different outcomes. Shock 2013, 39:480-487.
27. Calabrese J.M., Seila A.C., Yeo G.W., Sharp P.A. RNA sequence analysis defines Dicer's role in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 2007, 104:18097-18102.
28. Chen X., Li Q., Wang J., Guo X., Jiang X., Ren Z., Weng C., Sun G., Wang X., Liu Y., Ma L., Chen J.Y., Wang J., Zen K., Zhang J., Zhang C.Y. Identification and characterization of novel amphioxus microRNAs by Solexa sequencing. Genome Biol. 2009, 10:R78.
29. Oerlemans M.I., Mosterd A., Dekker M.S., de Vrey E.A., van Mil A., Pasterkamp G., Doevendans P.A., Hoes A.W., Sluijter J.P. Early assessment of acute coronary syndromes in the emergency department: the potential diagnostic value of circulating microRNAs. EMBO Mol. Med. 2012, 11:1176-1185.
30. Chen J., Yao D., Li Y., Chen H., He C., Ding N., Lu Y., Ou T., Zhao S., Li L., Long F. Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma. Int. J. Mol. Med. 2013, 3:557-567.
31. Wang F., Long G., Zhao C., Li H., Chaugai S., Wang Y., Chen C., Wang D.W. Plasma microRNA-133a is a new marker for both acute myocardial infarction and underlying coronary artery stenosis. J. Transl. Med. 2013, 11:222.
32. Gui J., Tian Y., Wen X., Zhang W., Zhang P., Gao J., et al. Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies. Clin. Sci. (Lond.) 2011, 5:183-193.
33. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C (T)). Method 2001, 4:402-408.
34. Persson H., Kvist A., Rego N., Staaf J., Vallon-Christersson J., Luts L., Loman N., Jonsson G., Naya H., Hoglund M., Borg A., Rovira C. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. Cancer Res. 2011, 71:78-86.
35. The Gene Ontology (GO) project in 2006. Nucleic Acids Res. 2006, 34:D322-326. C. Gene Ontology.
36. Ashburner M., Ball C.A., Blake J.A., Botstein D., Butler H., Cherry J.M., Davis A.P., Dolinski K., Dwight S.S., Eppig J.T., Harris M.A., Hill D.P., Issel-Tarver L., Kasarskis A., Lewis S., Matese J.C., Richardson J.E., Ringwald M., Rubin G.M., Sherlock G. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 2000, 25:25-29.
37. Liu N., Olson E.N. MicroRNA regulatory networks in cardiovascular development. Dev. Cell 2010, 18:510-525.
38. Friedman R.C., Farh K.K., Burge C.B., Bartel D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009, 19:92-105.
39. Chen X., Ba Y., Ma L., Cai X., Yin Y., Wang K., Guo J., Zhang Y., Chen J., Guo X., Li Q., Li X., Wang W., Zhang Y., Wang J., Jiang X., Xiang Y., Xu C., Zheng P., Zhang J., Li R., Zhang H., Shang X., Gong T., Ning G., Wang J., Zen K., Zhang J., Zhang C.Y. Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res. 2008, 18:997-1006.
40. Lawrie C.H., Gal S., Dunlop H.M., Pushkaran B., Liggins A.P., Pulford K., Banham A.H., Pezzella F., Boultwood J., Wainscoat J.S., Hatton C.S., Harris A.L. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br. J. Haematol. 2008, 141:672-675.
41. Mitchell P.S., Parkin R.K., Kroh E.M., Fritz B.R., Wyman S.K., Pogosova-Agadjanyan E.L., Peterson A., Noteboom J., O'Briant K.C., Allen A., Lin D.W., Urban N., Drescher C.W., Knudsen B.S., Stirewalt D.L., Gentleman R., Vessella R.L., Nelson P.S., Martin D.B., Tewari M. Circulating microRNAs as stable blood-based markers for cancer detection. Proc. Natl. Acad. Sci. USA 2008, 105:10513-10518.
42. Tijsen A.J., Creemers E.E., Moerland P.D., de Windt L.J., van der Wal A.C., Kok W.E., Pinto Y.M. MiR423-5p as a circulating biomarker for heart failure. Circ. Res. 2010, 106:1035-1039.
43. Habib S.S., A Al Masri A. Relationship of high sensitivity C-reactive protein with presence and severity of coronary artery disease. Pak. J. Med. Sci. 2013, 29:1425-1429.
44. Jialal I., Devaraj S. Inflammation and atherosclerosis: the value of the high-sensitivity C-reactive protein assay as a risk marker. Am. J. Clin. Pathol. 2001, 116(Suppl):S108-115.
45. Targher G. High-sensitivity C-reactive protein, obesity, and subclinical atherosclerosis: implications of JUPITER from the MESA study. Arterioscler., Thromb., Vasc. Biol. 2011, 31:1251-1252.
46. Masood A., Jafar S.S., Akram Z. Serum high sensitivity C-reactive protein levels and the severity of coronary atherosclerosis assessed by angiographic gensini score. JPMA, J. Pak. Med. Assoc. 2011, 61:325-327.
47. Ulucay A., Demirbag R., Yilmaz R., Unlu D., Gur M., Selek S., Celik H. The relationship between plasma C-reactive protein levels and presence and severity of coronary stenosis in patients with stable angina. Angiology 2007, 58:657-662.
48. Toth P.P. Subclinical atherosclerosis: what it is, what it means and what we can do about it. Int. J. Clin. Pract. 2008, 62:1246-1254.
49. Faxon D.P., Creager M.A., Smith S.C., Pasternak R.C., Olin J.W., Bettmann M.A., Criqui M.H., Milani R.V., Loscalzo J., Kaufman J.A., Jones D.W., Pearce W.H. Atherosclerotic vascular disease conference: executive summary: atherosclerotic vascular disease conference proceeding for healthcare professionals from a special writing group of the American Heart Association. Circulation 2004, 109:2595-2604. A. American Heart.
50. Lindow M., Kauppinen S. Discovering the first microRNA-targeted drug. J. Cell Biol. 2012, 199:407-412.