-
1
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A,. Cancer statistics, 2014. CA Cancer J Clin 2014; 64 (1): 9-29.
-
(2014)
CA Cancer J Clin
, vol.64
, Issue.1
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
2
-
-
67650996280
-
Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease
-
Acloque H, Adams MS, Fishwick K, Bronner-Fraser M, Nieto MA,. Epithelial-mesenchymal transitions: The importance of changing cell state in development and disease. J Clin Invest 2009; 119 (6): 1438-1449.
-
(2009)
J Clin Invest
, vol.119
, Issue.6
, pp. 1438-1449
-
-
Acloque, H.1
Adams, M.S.2
Fishwick, K.3
Bronner-Fraser, M.4
Nieto, M.A.5
-
3
-
-
70450198396
-
Epithelial-mesenchymal transitions in development and disease
-
Thiery JP, Acloque H, Huang RY, Nieto MA,. Epithelial-mesenchymal transitions in development and disease. Cell 2009; 139 (5): 871-890.
-
(2009)
Cell
, vol.139
, Issue.5
, pp. 871-890
-
-
Thiery, J.P.1
Acloque, H.2
Huang, R.Y.3
Nieto, M.A.4
-
4
-
-
77956178360
-
EMT, cancer stem cells and drug resistance: An emerging axis of evil in the war on cancer
-
Singh A, Settleman J,. EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer. Oncogene 2010; 29 (34): 4741-4751.
-
(2010)
Oncogene
, vol.29
, Issue.34
, pp. 4741-4751
-
-
Singh, A.1
Settleman, J.2
-
5
-
-
84901273062
-
HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL
-
Zhou ZJ, Dai Z, Zhou SL, Hu ZQ, Chen Q, Zhao YM, Shi YH, Gao Q, Wu WZ, Qiu SJ, Zhou J, Fan J,. HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL. Cancer Res 2014; 74 (10): 2750-2762.
-
(2014)
Cancer Res
, vol.74
, Issue.10
, pp. 2750-2762
-
-
Zhou, Z.J.1
Dai, Z.2
Zhou, S.L.3
Hu, Z.Q.4
Chen, Q.5
Zhao, Y.M.6
Shi, Y.H.7
Gao, Q.8
Wu, W.Z.9
Qiu, S.J.10
Zhou, J.11
Fan, J.12
-
6
-
-
79958265710
-
Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast
-
Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Rubin J, Richardson AL, Weinberg RA,. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell 2011; 145 (6): 926-940.
-
(2011)
Cell
, vol.145
, Issue.6
, pp. 926-940
-
-
Scheel, C.1
Eaton, E.N.2
Li, S.H.3
Chaffer, C.L.4
Reinhardt, F.5
Kah, K.J.6
Bell, G.7
Guo, W.8
Rubin, J.9
Richardson, A.L.10
Weinberg, R.A.11
-
7
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA,. Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9 (4): 265-273.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.4
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
8
-
-
67650999875
-
The basics of epithelial-mesenchymal transition
-
Kalluri R, Weinberg RA,. The basics of epithelial-mesenchymal transition. J Clin Invest 2009; 119 (6): 1420-1428.
-
(2009)
J Clin Invest
, vol.119
, Issue.6
, pp. 1420-1428
-
-
Kalluri, R.1
Weinberg, R.A.2
-
9
-
-
34548295877
-
Cell polarity in development and cancer
-
Wodarz A, Nathke I,. Cell polarity in development and cancer. Nat Cell Biol 2007; 9 (9): 1016-1024.
-
(2007)
Nat Cell Biol
, vol.9
, Issue.9
, pp. 1016-1024
-
-
Wodarz, A.1
Nathke, I.2
-
10
-
-
84871683461
-
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer
-
Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, Caldon CE, Stone A, Allerdice SL, Valdes-Mora F, Launchbury R, Statham AL, Armstrong N, Alles MC, Young A, Egger A, Au W, Piggin CL, Evans CJ, Ledger A, Brummer T, Oakes SR, Kaplan W, Gee JM, Nicholson RI, Sutherland RL, Swarbrick A, Naylor MJ, Clark SJ, Carroll JS, Ormandy CJ,. ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer. PLoS Biol 2012; 10 (12): e1001461.
-
(2012)
PLoS Biol
, vol.10
, Issue.12
, pp. e1001461
-
-
Kalyuga, M.1
Gallego-Ortega, D.2
Lee, H.J.3
Roden, D.L.4
Cowley, M.J.5
Caldon, C.E.6
Stone, A.7
Allerdice, S.L.8
Valdes-Mora, F.9
Launchbury, R.10
Statham, A.L.11
Armstrong, N.12
Alles, M.C.13
Young, A.14
Egger, A.15
Au, W.16
Piggin, C.L.17
Evans, C.J.18
Ledger, A.19
Brummer, T.20
Oakes, S.R.21
Kaplan, W.22
Gee, J.M.23
Nicholson, R.I.24
Sutherland, R.L.25
Swarbrick, A.26
Naylor, M.J.27
Clark, S.J.28
Carroll, J.S.29
Ormandy, C.J.30
more..
-
11
-
-
84869045299
-
Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2
-
Chakrabarti R, Hwang J, Andres Blanco M, Wei Y, Lukacisin M, Romano RA, Smalley K, Liu S, Yang Q, Ibrahim T, Mercatali L, Amadori D, Haffty BG, Sinha S, Kang Y,. Elf5 inhibits the epithelial-mesenchymal transition in mammary gland development and breast cancer metastasis by transcriptionally repressing Snail2. Nat Cell Biol 2012; 14 (11): 1212-1222.
-
(2012)
Nat Cell Biol
, vol.14
, Issue.11
, pp. 1212-1222
-
-
Chakrabarti, R.1
Hwang, J.2
Andres Blanco, M.3
Wei, Y.4
Lukacisin, M.5
Romano, R.A.6
Smalley, K.7
Liu, S.8
Yang, Q.9
Ibrahim, T.10
Mercatali, L.11
Amadori, D.12
Haffty, B.G.13
Sinha, S.14
Kang, Y.15
-
12
-
-
84862881087
-
Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling
-
Chakrabarti R, Wei Y, Romano RA, DeCoste C, Kang Y, Sinha S,. Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling. Stem Cells 2012; 30 (7): 1496-1508.
-
(2012)
Stem Cells
, vol.30
, Issue.7
, pp. 1496-1508
-
-
Chakrabarti, R.1
Wei, Y.2
Romano, R.A.3
Decoste, C.4
Kang, Y.5
Sinha, S.6
-
13
-
-
33645302628
-
The epithelial-mesenchymal transition: New insights in signaling, development, and disease
-
Lee JM, Dedhar S, Kalluri R, Thompson EW,. The epithelial-mesenchymal transition: New insights in signaling, development, and disease. J Cell Biol 2006; 172 (7): 973-981.
-
(2006)
J Cell Biol
, vol.172
, Issue.7
, pp. 973-981
-
-
Lee, J.M.1
Dedhar, S.2
Kalluri, R.3
Thompson, E.W.4
-
14
-
-
0032101178
-
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
-
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM,. Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J 1998; 17 (11): 3091-3100.
-
(1998)
EMBO J
, vol.17
, Issue.11
, pp. 3091-3100
-
-
Dennler, S.1
Itoh, S.2
Vivien, D.3
Ten Dijke, P.4
Huet, S.5
Gauthier, J.M.6
-
15
-
-
44449149171
-
Dynamic control of TGF-beta signaling and its links to the cytoskeleton
-
Moustakas A, Heldin CH,. Dynamic control of TGF-beta signaling and its links to the cytoskeleton. FEBS Lett 2008; 582 (14): 2051-2065.
-
(2008)
FEBS Lett
, vol.582
, Issue.14
, pp. 2051-2065
-
-
Moustakas, A.1
Heldin, C.H.2
-
16
-
-
34347331057
-
Roles of Smad3 in TGF-beta signaling during carcinogenesis
-
Millet C, Zhang YE,. Roles of Smad3 in TGF-beta signaling during carcinogenesis. Crit Rev Eukaryot Gene Expr 2007; 17 (14): 281-293.
-
(2007)
Crit Rev Eukaryot Gene Expr
, vol.17
, Issue.14
, pp. 281-293
-
-
Millet, C.1
Zhang, Y.E.2
-
17
-
-
31044448265
-
Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression
-
Jinnin M, Ihn H, Tamaki K,. Characterization of SIS3, a novel specific inhibitor of Smad3, and its effect on transforming growth factor-beta1-induced extracellular matrix expression. Mol Pharmacol 2006; 69 (2): 597-607.
-
(2006)
Mol Pharmacol
, vol.69
, Issue.2
, pp. 597-607
-
-
Jinnin, M.1
Ihn, H.2
Tamaki, K.3
-
18
-
-
84885612989
-
DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-beta-driven epithelial-mesenchymal transition
-
Chen N, Balasenthil S, Reuther J, Frayna A, Wang Y, Chandler DS, Abruzzo LV, Rashid A, Rodriguez J, Lozano G, Cao Y, Lokken E, Chen J, Frazier ML, Sahin AA, Wistuba II, Sen S, Lott ST, Killary AM,. DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-beta-driven epithelial-mesenchymal transition. Cancer Discov 2013; 3 (10): 1172-1189.
-
(2013)
Cancer Discov
, vol.3
, Issue.10
, pp. 1172-1189
-
-
Chen, N.1
Balasenthil, S.2
Reuther, J.3
Frayna, A.4
Wang, Y.5
Chandler, D.S.6
Abruzzo, L.V.7
Rashid, A.8
Rodriguez, J.9
Lozano, G.10
Cao, Y.11
Lokken, E.12
Chen, J.13
Frazier, M.L.14
Sahin, A.A.15
Wistuba, I.I.16
Sen, S.17
Lott, S.T.18
Killary, A.M.19
-
19
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA,. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133 (4): 704-715.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
Campbell, L.L.11
Polyak, K.12
Brisken, C.13
Yang, J.14
Weinberg, R.A.15
-
20
-
-
0029662049
-
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
-
Oft M, Peli J, Rudaz C, Schwarz H, Beug H, Reichmann E,. TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev 1996; 10 (19): 2462-2477.
-
(1996)
Genes Dev
, vol.10
, Issue.19
, pp. 2462-2477
-
-
Oft, M.1
Peli, J.2
Rudaz, C.3
Schwarz, H.4
Beug, H.5
Reichmann, E.6
-
21
-
-
77955286814
-
ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta
-
Hemberger M, Udayashankar R, Tesar P, Moore H, Burton GJ,. ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta. Hum Mol Genet 2010; 19 (12): 2456-2467.
-
(2010)
Hum Mol Genet
, vol.19
, Issue.12
, pp. 2456-2467
-
-
Hemberger, M.1
Udayashankar, R.2
Tesar, P.3
Moore, H.4
Burton, G.J.5
-
22
-
-
55549119925
-
Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5
-
Ng RK, Dean W, Dawson C, Lucifero D, Madeja Z, Reik W, Hemberger M,. Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. Nat Cell Biol 2008; 10 (11): 1280-1290.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.11
, pp. 1280-1290
-
-
Ng, R.K.1
Dean, W.2
Dawson, C.3
Lucifero, D.4
Madeja, Z.5
Reik, W.6
Hemberger, M.7
-
23
-
-
80053246340
-
Lineage specific methylation of the Elf5 promoter in mammary epithelial cells
-
Lee HJ, Hinshelwood RA, Bouras T, Gallego-Ortega D, Valdes-Mora F, Blazek K, Visvader JE, Clark SJ, Ormandy CJ,. Lineage specific methylation of the Elf5 promoter in mammary epithelial cells. Stem Cells 2011; 29 (10): 1611-1619.
-
(2011)
Stem Cells
, vol.29
, Issue.10
, pp. 1611-1619
-
-
Lee, H.J.1
Hinshelwood, R.A.2
Bouras, T.3
Gallego-Ortega, D.4
Valdes-Mora, F.5
Blazek, K.6
Visvader, J.E.7
Clark, S.J.8
Ormandy, C.J.9
-
24
-
-
77954822170
-
The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5
-
Hilton HN, Kalyuga M, Cowley MJ, Alles MC, Lee HJ, Caldon CE, Blazek K, Kaplan W, Musgrove EA, Daly RJ, Naylor MJ, Graham JD, Clarke CL, Ormandy CJ,. The antiproliferative effects of progestins in T47D breast cancer cells are tempered by progestin induction of the ETS transcription factor Elf5. Mol Endocrinol 2010; 24 (7): 1380-1392.
-
(2010)
Mol Endocrinol
, vol.24
, Issue.7
, pp. 1380-1392
-
-
Hilton, H.N.1
Kalyuga, M.2
Cowley, M.J.3
Alles, M.C.4
Lee, H.J.5
Caldon, C.E.6
Blazek, K.7
Kaplan, W.8
Musgrove, E.A.9
Daly, R.J.10
Naylor, M.J.11
Graham, J.D.12
Clarke, C.L.13
Ormandy, C.J.14
-
25
-
-
77949423550
-
Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants
-
Menzies KK, Lee HJ, Lefevre C, Ormandy CJ, Macmillan KL, Nicholas KR,. Insulin, a key regulator of hormone responsive milk protein synthesis during lactogenesis in murine mammary explants. Funct Integr Genomics 2010; 10 (1): 87-95.
-
(2010)
Funct Integr Genomics
, vol.10
, Issue.1
, pp. 87-95
-
-
Menzies, K.K.1
Lee, H.J.2
Lefevre, C.3
Ormandy, C.J.4
Macmillan, K.L.5
Nicholas, K.R.6
-
26
-
-
58949085251
-
Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate
-
Kendrick H, Regan JL, Magnay FA, Grigoriadis A, Mitsopoulos C, Zvelebil M, Smalley MJ,. Transcriptome analysis of mammary epithelial subpopulations identifies novel determinants of lineage commitment and cell fate. BMC Genomics 2008; 9: 591.
-
(2008)
BMC Genomics
, vol.9
, pp. 591
-
-
Kendrick, H.1
Regan, J.L.2
Magnay, F.A.3
Grigoriadis, A.4
Mitsopoulos, C.5
Zvelebil, M.6
Smalley, M.J.7
-
27
-
-
77956455343
-
Genome-wide search identifies Ccnd2 as a direct transcriptional target of Elf5 in mouse mammary gland
-
Escamilla-Hernandez R, Chakrabarti R, Romano RA, Smalley K, Zhu Q, Lai W, Halfon MS, Buck MJ, Sinha S,. Genome-wide search identifies Ccnd2 as a direct transcriptional target of Elf5 in mouse mammary gland. BMC Mol Biol 2010; 11: 68.
-
(2010)
BMC Mol Biol
, vol.11
, pp. 68
-
-
Escamilla-Hernandez, R.1
Chakrabarti, R.2
Romano, R.A.3
Smalley, K.4
Zhu, Q.5
Lai, W.6
Halfon, M.S.7
Buck, M.J.8
Sinha, S.9
-
28
-
-
40249108932
-
The Ets transcription factor Elf5 specifies mammary alveolar cell fate
-
Oakes SR, Naylor MJ, Asselin-Labat ML, Blazek KD, Gardiner-Garden M, Hilton HN, Kazlauskas M, Pritchard MA, Chodosh LA, Pfeffer PL, Lindeman GJ, Visvader JE, Ormandy CJ,. The Ets transcription factor Elf5 specifies mammary alveolar cell fate. Genes Dev 2008; 22 (5): 581-586.
-
(2008)
Genes Dev
, vol.22
, Issue.5
, pp. 581-586
-
-
Oakes, S.R.1
Naylor, M.J.2
Asselin-Labat, M.L.3
Blazek, K.D.4
Gardiner-Garden, M.5
Hilton, H.N.6
Kazlauskas, M.7
Pritchard, M.A.8
Chodosh, L.A.9
Pfeffer, P.L.10
Lindeman, G.J.11
Visvader, J.E.12
Ormandy, C.J.13
-
29
-
-
0346727324
-
Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction
-
Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A,. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest 2003; 112 (10): 1486-1494.
-
(2003)
J Clin Invest
, vol.112
, Issue.10
, pp. 1486-1494
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
30
-
-
30944466813
-
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
-
Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, Saika S, Flanders KC,. Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. Cytokine Growth Factor Rev 2006; 17 (1-2): 19-27.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, Issue.12
, pp. 19-27
-
-
Roberts, A.B.1
Tian, F.2
Byfield, S.D.3
Stuelten, C.4
Ooshima, A.5
Saika, S.6
Flanders, K.C.7
|