메뉴 건너뛰기




Volumn 21, Issue 2, 2015, Pages 428-435

Does a personal or family history of malignancy preclude the use of immunomodulators and biologics in IBD

Author keywords

Biologics; Inflammatory bowel disease; Lymphoma; Malignancy; Methotrexate; Skin cancer; Thiopurines

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; CYCLOSPORIN; HYDROXYCHLOROQUINE; IMMUNOMODULATING AGENT; MERCAPTOPURINE; METHOTREXATE; NATALIZUMAB; SALAZOSULFAPYRIDINE; VEDOLIZUMAB; BIOLOGICAL PRODUCT; IMMUNOLOGIC FACTOR;

EID: 84927724692     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000211     Document Type: Review
Times cited : (10)

References (82)
  • 1
    • 84876356567 scopus 로고    scopus 로고
    • Risk of extraintestinal solid cancer with anti-TNF therapy in adults with inflammatory bowel disease: Review of the literature
    • Hudesman D, Lichtiger S, Sands B. Risk of extraintestinal solid cancer with anti-TNF therapy in adults with inflammatory bowel disease: review of the literature. Inflamm Bowel Dis. 2013;19:644-649.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 644-649
    • Hudesman, D.1    Lichtiger, S.2    Sands, B.3
  • 2
    • 84892449056 scopus 로고    scopus 로고
    • Risk of cancer in patients with inflammatory bowel disease: A nationwide population-based cohort study with 30 years of follow up evaluation
    • Kappelman MD, Farkas DK, Long MD, et al. Risk of cancer in patients with inflammatory bowel disease: A nationwide population-based cohort study with 30 years of follow up evaluation. Clin Gastroenterol Hepatol. 2014;12:265-273.
    • (2014) Clin Gastroenterol, Hepatol , vol.12 , pp. 265-273
    • Kappelman, M.D.1    Farkas, D.K.2    Long, M.D.3
  • 3
    • 79958038543 scopus 로고    scopus 로고
    • Crohns disease and small bowel adenocarcinoma: A population-based case-control study
    • Shaukat A, Virnig DJ, Howard D. Crohns disease and small bowel adenocarcinoma: A population-based case-control study. Cancer Epidemiol Biomarkers Prev. 2011;20:1120-1123.
    • (2011) Cancer Epidemiol Biomarkers Prev , vol.20 , pp. 1120-1123
    • Shaukat, A.1    Virnig, D.J.2    Howard, D.3
  • 4
    • 0141651527 scopus 로고    scopus 로고
    • Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease
    • Munkholm P. Review article: The incidence and prevalence of colorectal cancer in inflammatory bowel disease. Aliment Pharmacol Ther. 2003;18 (suppl 2):1-5.
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 1-5
    • Munkholm, P.1
  • 5
    • 84864859115 scopus 로고    scopus 로고
    • Colorectal cancer in inflammatory bowel disease: What is the real magnitude of risk?
    • Dyson JK, Rutter MD. Colorectal cancer in inflammatory bowel disease: what is the real magnitude of risk?. World J Gastroenterol. 2012;18: 3839-3848.
    • (2012) World J Gastroenterol , vol.18 , pp. 3839-3848
    • Dyson, J.K.1    Rutter, M.D.2
  • 6
    • 0035080617 scopus 로고    scopus 로고
    • The risk of colorectal cancer in ulcerative colitis: A meta-analysis
    • Eaden JA, Abrams KR, Mayberry JF. The risk of colorectal cancer in ulcerative colitis: A meta-analysis. Gut. 2001;48:526-535.
    • (2001) Gut , vol.48 , pp. 526-535
    • Eaden, J.A.1    Abrams, K.R.2    Mayberry, J.F.3
  • 7
    • 84884656587 scopus 로고    scopus 로고
    • Declining risk of colorectal cancer in inflammatory bowel disease: An updated metaanalysis of population-based cohort studies
    • Lutgens W, Van Oijen MG, Van der Heijden GJ, et al. Declining risk of colorectal cancer in inflammatory bowel disease: An updated metaanalysis of population-based cohort studies. Inflamm Bowel Dis. 2013; 19:789-799.
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 789-799
    • Lutgens, W.1    Van Oijen, M.G.2    Van Der Heijden, G.J.3
  • 8
    • 65349196054 scopus 로고    scopus 로고
    • Decreasing time-trends of colorectal cancer in a large cohort of patients with inflammatory bowel disease
    • quiz 1818-1819
    • Söderlund S, Brandt L, Lapidus A, et al. Decreasing time-trends of colorectal cancer in a large cohort of patients with inflammatory bowel disease. Gastroenterology. 2009;136:1561-1567; quiz 1818-1819.
    • (2009) Gastroenterology , vol.136 , pp. 1561-1567
    • Söderlund, S.1    Brandt, L.2    Lapidus, A.3
  • 9
    • 0025167285 scopus 로고
    • Increased risk of large-bowel cancer in Crohn's disease with colonic involvement
    • Ekbom A, Helmick C, Zack M, et al. Increased risk of large-bowel cancer in Crohn's disease with colonic involvement. Lancet. 1990;336:357-359.
    • (1990) Lancet , vol.336 , pp. 357-359
    • Ekbom, A.1    Helmick, C.2    Zack, M.3
  • 10
    • 84880580928 scopus 로고    scopus 로고
    • Primary sclerosing cholangitis: Diagnosis, prognosis, and management
    • Singh S, Talwalkar JA. Primary sclerosing cholangitis: diagnosis, prognosis, and management. Clin Gastroenterol Hepatol. 2013;11:898-907.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 898-907
    • Singh, S.1    Talwalkar, J.A.2
  • 11
    • 80055062562 scopus 로고    scopus 로고
    • Cancer surveillance in patients with primary sclerosing cholangitis
    • Razumilava N, Gores GJ, Lindor KD. Cancer surveillance in patients with primary sclerosing cholangitis. Hepatology. 2011;54:1842-1852.
    • (2011) Hepatology , vol.54 , pp. 1842-1852
    • Razumilava, N.1    Gores, G.J.2    Lindor, K.D.3
  • 12
    • 1942440342 scopus 로고    scopus 로고
    • Incidence and risk factors for cholangiocarcinoma in primary sclerosing cholangitis
    • Burak K, Angulo P, Pasha TM, et al. Incidence and risk factors for cholangiocarcinoma in primary sclerosing cholangitis. Am J Gastroenterol. 2004;99:523-526.
    • (2004) Am J Gastroenterol , vol.99 , pp. 523-526
    • Burak, K.1    Angulo, P.2    Pasha, T.M.3
  • 13
    • 33644892763 scopus 로고    scopus 로고
    • Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis
    • Baecklund E, Iliadou A, Askling J, et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis Rheum. 2006;54:692-701.
    • (2006) Arthritis Rheum , vol.54 , pp. 692-701
    • Baecklund, E.1    Iliadou, A.2    Askling, J.3
  • 14
    • 0034764110 scopus 로고    scopus 로고
    • Inflammatory bowel disease is not associated with an increased risk of lymphoma
    • Lewis JD, Bilker WB, Brensinger C, et al. Inflammatory bowel disease is not associated with an increased risk of lymphoma. Gastroenterology. 2001;121:1080-1087.
    • (2001) Gastroenterology , vol.121 , pp. 1080-1087
    • Lewis, J.D.1    Bilker, W.B.2    Brensinger, C.3
  • 15
    • 17644386242 scopus 로고    scopus 로고
    • Risk of haematopoietic cancer in patients with inflammatory bowel disease
    • Askling J, Brandt L, Lapidus A, et al. Risk of haematopoietic cancer in patients with inflammatory bowel disease. Gut. 2005;54:617-622.
    • (2005) Gut , vol.54 , pp. 617-622
    • Askling, J.1    Brandt, L.2    Lapidus, A.3
  • 16
    • 80051480954 scopus 로고    scopus 로고
    • Risk of malignant lymphoma in patients with inflammatory bowel diseases: A Dutch nationwide study
    • Vos AC, Bakkal N, Minnee RC, et al. Risk of malignant lymphoma in patients with inflammatory bowel diseases: A Dutch nationwide study. Inflamm Bowel Dis. 2011;17:1837-1845.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1837-1845
    • Vos, A.C.1    Bakkal, N.2    Minnee, R.C.3
  • 17
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine or combination therapy for Crohn's disease
    • Colombrel JF, Sandborn W, Reinisch W, et al. Infliximab, azathioprine or combination therapy for Crohn's disease. N Engl J Med. 2010;362:1383-1395.
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombrel, J.F.1    Sandborn, W.2    Reinisch, W.3
  • 18
    • 70149110219 scopus 로고    scopus 로고
    • Mutagenicity and potential carcinogenesis of thiopurine treatment in patients with inflammatory bowel disease
    • Ngueyn T, Vacek PM, O'Neil P, et al. Mutagenicity and potential carcinogenesis of thiopurine treatment in patients with inflammatory bowel disease. Cancer Res. 2009;69:7004-7012.
    • (2009) Cancer Res , vol.69 , pp. 7004-7012
    • Ngueyn, T.1    Vacek, P.M.2    O'neil, P.3
  • 19
    • 34547116188 scopus 로고    scopus 로고
    • Thiopurines, DNA damage, DNA repair and therapy-related cancer
    • Karran P. Thiopurines, DNA damage, DNA repair and therapy-related cancer. Br Med Bull. 2006;79-80:153-170.
    • (2006) Br Med Bull , vol.79-80 , pp. 153-170
    • Karran, P.1
  • 20
    • 84878557076 scopus 로고    scopus 로고
    • Use of azathioprine and the risk of cancer in inflammatory bowel disease
    • Pasternak B, Svanstrom H, Schmiegelow K, et al. Use of azathioprine and the risk of cancer in inflammatory bowel disease. Am J Epidemiol. 2013; 177:1296-1305.
    • (2013) Am J Epidemiol , vol.177 , pp. 1296-1305
    • Pasternak, B.1    Svanstrom, H.2    Schmiegelow, K.3
  • 21
    • 33745713650 scopus 로고    scopus 로고
    • Post-transplant de novo malignancies in renal transplant recipients: The past and present
    • Kauffman HM, Cherikh WS, McBride MA, et al. Post-transplant de novo malignancies in renal transplant recipients: The past and present. Transpl Int. 2006;19:607-620.
    • (2006) Transpl Int , vol.19 , pp. 607-620
    • Kauffman, H.M.1    Cherikh, W.S.2    Mcbride, M.A.3
  • 22
    • 1342304173 scopus 로고    scopus 로고
    • Lymphomas after solid organ transplantation: A collaborative transplant study report
    • Opelz G, Dohler B. Lymphomas after solid organ transplantation: A collaborative transplant study report. Am J Transplant. 2004;4:222-230.
    • (2004) Am J Transplant , vol.4 , pp. 222-230
    • Opelz, G.1    Dohler, B.2
  • 23
    • 0041831304 scopus 로고    scopus 로고
    • Influence of immunosuppression on the prevalence of cancer after kidney transplantation
    • Marcen R, Pascual J, Tato AM, et al. Influence of immunosuppression on the prevalence of cancer after kidney transplantation. Transplant Proc. 2003;35:1714-1716.
    • (2003) Transplant Proc , vol.35 , pp. 1714-1716
    • Marcen, R.1    Pascual, J.2    Tato, A.M.3
  • 24
    • 84884266305 scopus 로고    scopus 로고
    • Use of immunosuppressants and biologics in patients with previous cancer
    • Beaugerie L. Use of immunosuppressants and biologics in patients with previous cancer. Dig Dis. 2013;31:254-259.
    • (2013) Dig Dis , vol.31 , pp. 254-259
    • Beaugerie, L.1
  • 25
    • 22644446331 scopus 로고    scopus 로고
    • Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine
    • Kandiel A, Fraser AG, Korelitz BI, et al. Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut. 2005:54:1121-1125.
    • (2005) Gut , vol.54 , pp. 1121-1125
    • Kandiel, A.1    Fraser, A.G.2    Korelitz, B.I.3
  • 26
    • 70449100743 scopus 로고    scopus 로고
    • Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: A prospective observation cohort study
    • Beaugerie L, Brousse N, Bouvier AM, et al. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: A prospective observation cohort study. Lancet. 2009;364:1617-1625.
    • (2009) Lancet , vol.364 , pp. 1617-1625
    • Beaugerie, L.1    Brousse, N.2    Bouvier, A.M.3
  • 27
    • 77954426838 scopus 로고    scopus 로고
    • Risk of cancer in inflammatory bowel disease treated with azathioprine: A UK population-based case-control study
    • Armstrong RG, West J, Card TR. Risk of cancer in inflammatory bowel disease treated with azathioprine: A UK population-based case-control study. Am J Gastroenterol. 2010;105:1604-1609.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1604-1609
    • Armstrong, R.G.1    West, J.2    Card, T.R.3
  • 28
    • 24944519200 scopus 로고    scopus 로고
    • Azathioprine and UVA light generate mutagenic oxidative DNA damage
    • O'Donovan P, Perrett CM, Zhang X, et al. Azathioprine and UVA light generate mutagenic oxidative DNA damage. Science. 2005;309:1871-1874.
    • (2005) Science , vol.309 , pp. 1871-1874
    • O'Donovan, P.1    Perrett, C.M.2    Zhang, X.3
  • 29
    • 80054862378 scopus 로고    scopus 로고
    • Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease
    • Peyrin-Biroulet L, Khosrotehrani K, Carrat F, et al. Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology. 2011:141:1621-1628 e1-5.
    • (2011) Gastroenterology , vol.141 , pp. 1621-1628
    • Peyrin-Biroulet, L.1    Khosrotehrani, K.2    Carrat, F.3
  • 30
    • 84856193112 scopus 로고    scopus 로고
    • Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of nonmelanoma skin cancer in an at-risk population: A cohort study
    • Setshedi M, Epstein D, Winter T, et al. Use of thiopurines in the treatment of inflammatory bowel disease is associated with an increased risk of nonmelanoma skin cancer in an at-risk population: A cohort study. J Gastroenterol Hepatol. 2012;27:385-389.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 385-389
    • Setshedi, M.1    Epstein, D.2    Winter, T.3
  • 31
    • 84893772239 scopus 로고    scopus 로고
    • Association between thiopurine use and nonmelanoma skin cancers in patients with inflammatory bowel disease: A meta-analysis
    • Ariyaratnam J, Subramanian V. Association between thiopurine use and nonmelanoma skin cancers in patients with inflammatory bowel disease: A meta-analysis. Am J Gastroenterol. 2014;109:163-169.
    • (2014) Am J Gastroenterol , vol.109 , pp. 163-169
    • Ariyaratnam, J.1    Subramanian, V.2
  • 32
    • 0037464506 scopus 로고    scopus 로고
    • Skin cancers after organ transplantation
    • Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med. 2003;2003:1681-1691.
    • (2003) N Engl J Med , vol.2003 , pp. 1681-1691
    • Euvrard, S.1    Kanitakis, J.2    Claudy, A.3
  • 33
    • 84890555688 scopus 로고    scopus 로고
    • Increased incidence of squamous cell carcinoma of the skin after long term treatment with azathioprine in patients with auto-immune inflammatory rheumatic diseases
    • van den Reek J, van Lümig P, Janssen M, et al. Increased incidence of squamous cell carcinoma of the skin after long term treatment with azathioprine in patients with auto-immune inflammatory rheumatic diseases. J Eur Acad Dermatol Venereol. 2014;28:27-33.
    • (2014) J Eur Acad Dermatol Venereol , vol.28 , pp. 27-33
    • Van Dan Reek, J.1    Van Lümig, P.2    Janssen, M.3
  • 34
    • 84864225717 scopus 로고    scopus 로고
    • Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease
    • Long MD, Martin CF, Pipkin CA, et al. Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. Gastroenterology. 2012;143:390-399.
    • (2012) Gastroenterology , vol.143 , pp. 390-399
    • Long, M.D.1    Martin, C.F.2    Pipkin, C.A.3
  • 35
    • 77953801701 scopus 로고    scopus 로고
    • Review article: Malignancy on thiopurine treatment with special reference to inflammatory bowel disease
    • Smith MA, Irving PM, Marinaki AM, et al. Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease. Aliment Pharmacol Ther. 2010;32:119-130.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 119-130
    • Smith, M.A.1    Irving, P.M.2    Marinaki, A.M.3
  • 36
    • 0027310972 scopus 로고
    • Brief report: Reversible lymphomas associated with Epstein Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis
    • Kamel OW, Van De Rijn M, Weiss LM, et al. Brief report: reversible lymphomas associated with Epstein Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. N Engl J Med. 1993;328:1317-1321.
    • (1993) N Engl J Med , vol.328 , pp. 1317-1321
    • Kamel, O.W.1    Van De Rijn, M.2    Weiss, L.M.3
  • 37
    • 0034046385 scopus 로고    scopus 로고
    • Psoriasis, its treatment, and cancer in a cohort of Finish patients
    • Hannuksela-Svhan A, Pukkala E, Laara E, et al. Psoriasis, its treatment, and cancer in a cohort of Finish patients. J Invest Dermatol. 2000;114:587-590.
    • (2000) J Invest Dermatol , vol.114 , pp. 587-590
    • Hannuksela-Svhan, A.1    Pukkala, E.2    Laara, E.3
  • 38
    • 0036624739 scopus 로고    scopus 로고
    • Lymphomas in rheumatoid arthritis patients treated with methotrexate: A 3 year prospective study in France
    • Mariette X, Casals-Hatem D, Warszawki J, et al. Lymphomas in rheumatoid arthritis patients treated with methotrexate: A 3 year prospective study in France. Blood. 2002;99:3909-3915.
    • (2002) Blood , vol.99 , pp. 3909-3915
    • Mariette, X.1    Casals-Hatem, D.2    Warszawki, J.3
  • 39
    • 45349083403 scopus 로고    scopus 로고
    • Incidence of melanoma and other malignancies among rheumatoid arthritis patients treated with methotrexate
    • Buchbinder R, Barber M, Heuzenroeder L, et al. Incidence of melanoma and other malignancies among rheumatoid arthritis patients treated with methotrexate. Arthritis Rheum. 2008;59:794-799.
    • (2008) Arthritis Rheum , vol.59 , pp. 794-799
    • Buchbinder, R.1    Barber, M.2    Heuzenroeder, L.3
  • 40
    • 67549107120 scopus 로고    scopus 로고
    • Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic literature research
    • Salliot C, van der-Heijde D. Long-term safety of methotrexate monotherapy in patients with rheumatoid arthritis: A systematic literature research. Ann Rheum Dis. 2009;68:1100-1104.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1100-1104
    • Salliot, C.1    Van Der -Heijde, D.2
  • 41
    • 0033795223 scopus 로고    scopus 로고
    • Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low
    • Farrell RJ, Ang Y, Kileen P, et al. Increased incidence of non-Hodgkin's lymphoma in inflammatory bowel disease patients on immunosuppressive therapy but overall risk is low. Gut. 2000;47:514-519.
    • (2000) Gut , vol.47 , pp. 514-519
    • Farrell, R.J.1    Ang, Y.2    Kileen, P.3
  • 42
    • 78149272887 scopus 로고    scopus 로고
    • Pharmacologic immunomodulation and cutaneous malignancy in rheumatoid arthritis, psoriasis, and psoriatic arthritis
    • Krathen MS, Gottlieb AB, Mease PJ. Pharmacologic immunomodulation and cutaneous malignancy in rheumatoid arthritis, psoriasis, and psoriatic arthritis. J Rheumatol. 2010;37:2205-2215.
    • (2010) J Rheumatol , vol.37 , pp. 2205-2215
    • Krathen, M.S.1    Gottlieb, A.B.2    Mease, P.J.3
  • 43
    • 80054865266 scopus 로고    scopus 로고
    • Increased risk of nonmelanoma skin cancers among individuals with inflammatory bowel disease
    • Singh H, Nugent Z, Demers AA, et al. Increased risk of nonmelanoma skin cancers among individuals with inflammatory bowel disease. Gastroenterology. 2011;141:1612-1620.
    • (2011) Gastroenterology , vol.141 , pp. 1612-1620
    • Singh, H.1    Nugent, Z.2    Demers, A.A.3
  • 44
    • 84857801058 scopus 로고    scopus 로고
    • Inflammatory bowel disease therapies and cancer risk: Where are we and where are we going?
    • Beaugerie L. Inflammatory bowel disease therapies and cancer risk: where are we and where are we going? Gut. 2012;61:476-483.
    • (2012) Gut , vol.61 , pp. 476-483
    • Beaugerie, L.1
  • 45
    • 80053565309 scopus 로고    scopus 로고
    • Malignancies associated with tumour necrosis factor inhibitors in registries and prospective observational studies: A systematic review and meta-analysis
    • Mariette X, MatucciM, Pavelka K, et al. Malignancies associated with tumour necrosis factor inhibitors in registries and prospective observational studies: A systematic review and meta-analysis. Ann Rheum Dis. 2011;70:1895-1904.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1895-1904
    • Mariette, X.1    Matucci, M.2    Pavelka, K.3
  • 46
    • 33646696885 scopus 로고    scopus 로고
    • Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: Systematic review and meta-analysis of rare harmful effects in randomized controlled trials
    • Bongartz T, Sutton AJ, Sweeting MJ, et al. Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies: systematic review and meta-analysis of rare harmful effects in randomized controlled trials. JAMA. 2006;295:2275-2285.
    • (2006) JAMA , vol.295 , pp. 2275-2285
    • Bongartz, T.1    Sutton, A.J.2    Sweeting, M.J.3
  • 47
    • 0032738644 scopus 로고    scopus 로고
    • The relationship between infliximab treatment and lymphoma in Crohn's disease
    • Bickston SJ, Lichtenstein GR, Arseneau KO, et al. The relationship between infliximab treatment and lymphoma in Crohn's disease. Gastroenterology. 1999;177:1433-1437.
    • (1999) Gastroenterology , vol.177 , pp. 1433-1437
    • Bickston, S.J.1    Lichtenstein, G.R.2    Arseneau, K.O.3
  • 49
    • 0036900501 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist therapy and lymphoma development: Twenty six cases reported to the Food and Drug Administration
    • Brown SL, Greene MH, Gershon SK, et al. Tumor necrosis factor antagonist therapy and lymphoma development: Twenty six cases reported to the Food and Drug Administration. Arthritis Rheum. 2002:46;3151-3158.
    • (2002) Arthritis Rheum , vol.46 , pp. 3151-3158
    • Brown, S.L.1    Greene, M.H.2    Gershon, S.K.3
  • 50
    • 84905027083 scopus 로고    scopus 로고
    • Accessed September 10
    • Remicade: Full Prescribing Information. Available at: http://www.remicade.com/shared/product/remicade/prescribing-information.pdf. Accessed September 10, 2014.
    • (2014) Full Prescribing Information
  • 51
    • 67949112671 scopus 로고    scopus 로고
    • Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: A meta-analysis
    • Siegel CA, Marden SM, Persing SM, et al. Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: A meta-analysis. Clin Gastroenterol Hepatol. 2009;7:874-881.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 874-881
    • Siegel, C.A.1    Marden, S.M.2    Persing, S.M.3
  • 52
    • 84896488437 scopus 로고    scopus 로고
    • Increased risk of malignancy with adalimumab combination therapy, compared with monotherapy, for Crohn's disease
    • Osterman M, Sandborn WJ, Colombel J, et al. Increased risk of malignancy with adalimumab combination therapy, compared with monotherapy, for Crohn's disease. Gastroenterology. 2014;146:941-946.
    • (2014) Gastroenterology , vol.146 , pp. 941-946
    • Osterman, M.1    Sandborn, W.J.2    Colombel, J.3
  • 53
    • 84872024555 scopus 로고    scopus 로고
    • T cell non-Hodgkin's lymphomas reported to the FDA AERS with tumor necrosis factor-alpha inhibitors: Results of the REFURBISH study
    • Deepak P, Sifuentes H, Sherid M, et al. T cell non-Hodgkin's lymphomas reported to the FDA AERS with tumor necrosis factor-alpha inhibitors: results of the REFURBISH study. Am J Gastroenterol. 2013;108:99-105.
    • (2013) Am J Gastroenterol , vol.108 , pp. 99-105
    • Deepak, P.1    Sifuentes, H.2    Sherid, M.3
  • 54
    • 84893787330 scopus 로고    scopus 로고
    • Drug therapies and the risk of malignancy in Crohn's disease: Results from the TREAT registry
    • Lichtenstein GR, Feagan BG, Cohen RC, et al. Drug therapies and the risk of malignancy in Crohn's disease: results from the TREAT registry. Am J Gastroenterol. 2014;109:212-223.
    • (2014) Am J Gastroenterol , vol.109 , pp. 212-223
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.C.3
  • 55
    • 84902574301 scopus 로고    scopus 로고
    • Association between tumor necrosis factor-alpha antagonists and risk of cancer in patients with inflammatory bowel disease
    • Andersen NN, Pasternak N, Basit S, et al. Association between tumor necrosis factor-alpha antagonists and risk of cancer in patients with inflammatory bowel disease. JAMA. 2014;311:2406-2413.
    • (2014) JAMA , vol.311 , pp. 2406-2413
    • Andersen, N.N.1    Pasternak, N.2    Basit, S.3
  • 56
    • 84893734901 scopus 로고    scopus 로고
    • Systematic review with metaanalysis: Malignancies with anti-tumor necrosis factor alpha therapy in inflammatory bowel disease
    • Williams CJM, Peyrin-Biroulet L, Ford AC. Systematic review with metaanalysis: malignancies with anti-tumor necrosis factor alpha therapy in inflammatory bowel disease. Aliment Pharmacol Ther. 2014;39:447-458.
    • (2014) Aliment Pharmacol Ther , vol.39 , pp. 447-458
    • Williams, C.J.M.1    Peyrin-Biroulet, L.2    Ford, A.C.3
  • 57
    • 0347991877 scopus 로고    scopus 로고
    • The safety profile of infliximab in patients with Crohn's disease: The Mayo clinic experience in 500 patients
    • Colombel JF, Loftus EV Jr, Tremaine WJ, et al. The safety profile of infliximab in patients with Crohn's disease: The Mayo clinic experience in 500 patients. Gastroenterology. 2004;126:19-31.
    • (2004) Gastroenterology , vol.126 , pp. 19-31
    • Colombel, J.F.1    Loftus, E.V.2    Tremaine, W.J.3
  • 58
    • 82955195113 scopus 로고    scopus 로고
    • Role of thiopurine and anti-TNF therapy in lymphoma in inflammatory bowel disease
    • Herrinton LJ, Liu L, Weng X, et al. Role of thiopurine and anti-TNF therapy in lymphoma in inflammatory bowel disease. Am J Gastroenterol. 2011;106:2146-2153.
    • (2011) Am J Gastroenterol , vol.106 , pp. 2146-2153
    • Herrinton, L.J.1    Liu, L.2    Weng, X.3
  • 59
    • 84871656960 scopus 로고    scopus 로고
    • Lymphoma and other lymphoproliferative disorders in inflammatory bowel disease: A review
    • Subramanian K, D'Rozario J, Pavli P. Lymphoma and other lymphoproliferative disorders in inflammatory bowel disease: A review. J Gastroenterol Hepatol. 2013;28:24-30.
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 24-30
    • Subramanian, K.1    D'rozario, J.2    Pavli, P.3
  • 60
    • 84896849512 scopus 로고    scopus 로고
    • Hepatosplenic T-cell lymphoma, immunosuppressive agents and biological: What are the risks?
    • Subramanian K, Yeng D, Grimpen F, et al. Hepatosplenic T-cell lymphoma, immunosuppressive agents and biological: what are the risks?. Intern Med J. 2014;44:287-290.
    • (2014) Intern Med J , vol.44 , pp. 287-290
    • Subramanian, K.1    Yeng, D.2    Grimpen, F.3
  • 61
    • 80955142690 scopus 로고    scopus 로고
    • Hepatosplenic T-cell lymphoma in patients receiving TNF-a inhibitor therapy: Expanding the groups at risk
    • Parakkal D, Sifuentes H, Semer R, et al. Hepatosplenic T-cell lymphoma in patients receiving TNF-a inhibitor therapy: expanding the groups at risk. Eur J Gastroenterol Heptaol. 2011;23:1150-1156.
    • (2011) Eur J Gastroenterol Heptaol , vol.23 , pp. 1150-1156
    • Parakkal, D.1    Sifuentes, H.2    Semer, R.3
  • 62
    • 84905027083 scopus 로고    scopus 로고
    • Abbvie. Available at:, Accessed September 10
    • Abbvie. Humira: Full Prescribing Information. Available at: http://www.rxabbvie.com/pdf/humira.pdf. Accessed September 10, 2014.
    • (2014) Humira: Full Prescribing Information
  • 63
    • 56749151619 scopus 로고    scopus 로고
    • Serious events with infliximab in patients with inflammatory bowel disease: A 9 year cohort study in the Netherlands
    • De Vries HS, van Oijen GH, de Jong DJ. Serious events with infliximab in patients with inflammatory bowel disease: A 9 year cohort study in the Netherlands. Drug Saf. 2008;31:1135-1144.
    • (2008) Drug Saf , vol.31 , pp. 1135-1144
    • De Veirs, H.S.1    Van Oijen, G.H.2    De Jong, D.J.3
  • 64
    • 75749141691 scopus 로고    scopus 로고
    • Infliximab safety profile and long term applicability in inflammatory bowel disease: A 9 year experience in clinical practice
    • Zabana Y, Domenech E, Manosa M, et al. Infliximab safety profile and long term applicability in inflammatory bowel disease: A 9 year experience in clinical practice. Aliment Pharmacol Ther. 2010;31:553-560.
    • (2010) Aliment Pharmacol Ther , vol.31 , pp. 553-560
    • Zabana, Y.1    Domenech, E.2    Manosa, M.3
  • 65
    • 84922728949 scopus 로고    scopus 로고
    • Long-term safety and efficacy of natalizumab in relapsing-remitting multiple sclerosis: Impact on quality of life
    • Planas R, Martin R, Sospedra M. Long-term safety and efficacy of natalizumab in relapsing-remitting multiple sclerosis: impact on quality of life. Patient Relat Outcome Meas. 2014;5:25-33.
    • (2014) Patient Relat Outcome Meas , vol.5 , pp. 25-33
    • Planas, R.1    Martin, R.2    Sospedra, M.3
  • 66
    • 72749090843 scopus 로고    scopus 로고
    • Melanoma in multiple sclerosis treatedwith natalizumab: Causal association or coincidence?
    • Bergamaschi R, Montomoli C. Melanoma in multiple sclerosis treatedwith natalizumab: causal association or coincidence? Mult Scer. 2009;15: 1532-1533.
    • (2009) Mult Scer , vol.15 , pp. 1532-1533
    • Bergamaschi, R.1    Montomoli, C.2
  • 67
    • 38949166754 scopus 로고    scopus 로고
    • Melanoma complicating treatment with natalizumab for multiple sclerosis
    • Mullen JT, Vartanian TK, Atkins MB. Melanoma complicating treatment with natalizumab for multiple sclerosis. N Engl J Med. 2008; 358:647-648.
    • (2008) N Engl J Med , vol.358 , pp. 647-648
    • Mullen, J.T.1    Vartanian, T.K.2    Atkins, M.B.3
  • 68
    • 70349652532 scopus 로고    scopus 로고
    • Melanoma complicating treatment with natalizumab (tysabri) for multiple sclerosis
    • Ismail A, Kemp J, Sharrack B. Melanoma complicating treatment with natalizumab (tysabri) for multiple sclerosis. J Neurol. 2009;256:1771-1772.
    • (2009) J Neurol , vol.256 , pp. 1771-1772
    • Ismail, A.1    Kemp, J.2    Sharrack, B.3
  • 69
    • 79551586049 scopus 로고    scopus 로고
    • Association of melanoma and natalizumab therapy in the Italian MS population: A second case report
    • Laroni A, Bedognetti M, Uccelli A, et al. Association of melanoma and natalizumab therapy in the Italian MS population: A second case report. Neurol Sci. 2011;32:181-182.
    • (2011) Neurol Sci , vol.32 , pp. 181-182
    • Laroni, A.1    Bedognetti, M.2    Uccelli, A.3
  • 70
    • 70349440918 scopus 로고    scopus 로고
    • Primary central nervous system lymphoma in a patient treated with natalizumab
    • Schweikert A, Kremer M, Ringel F, et al. Primary central nervous system lymphoma in a patient treated with natalizumab. Ann Neurol. 2009;66: 403-406.
    • (2009) Ann Neurol , vol.66 , pp. 403-406
    • Schweikert, A.1    Kremer, M.2    Ringel, F.3
  • 71
    • 84862679547 scopus 로고    scopus 로고
    • Natalizumab-associated complication? First case of peripheral T cell lymphoma
    • Schowinsky J, Corboy J, Vollmer T, et al. Natalizumab-associated complication? First case of peripheral T cell lymphoma. Acta Neuropathol. 2012;123:751-752.
    • (2012) Acta Neuropathol , vol.123 , pp. 751-752
    • Schowinsky, J.1    Corboy, J.2    Vollmer, T.3
  • 72
    • 27644441529 scopus 로고    scopus 로고
    • Natalizumab induction and maintenance therapy for Crohn's disease: The ENACT-1 and ENACT-2 trials
    • Sanborn WJ, Colombel JF, Enns R, et al. Natalizumab induction and maintenance therapy for Crohn's disease: The ENACT-1 and ENACT-2 trials. N Eng J Med. 2005;353:1912-1925.
    • (2005) N Eng J Med , vol.353 , pp. 1912-1925
    • Sanborn, W.J.1    Colombel, J.F.2    Enns, R.3
  • 73
    • 84927746294 scopus 로고    scopus 로고
    • Takeda Pharmaceuticals U.S.A. Inc. Vedolizumab, Available at, Accessed September 10
    • Takeda Pharmaceuticals U.S.A., Inc. Vedolizumab: Advisory committee briefing document. Available at: http://www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials/drugs/gastrointestinaldrugsadvisorycommittee/ucm377621.pdf. Accessed September 10, 2014.
    • (2014) Advisory Committee Briefing Document
  • 74
    • 84885618122 scopus 로고    scopus 로고
    • The management of immunosuppression in patients with inflammatory bowel disease and cancer
    • Bernheim O, Colombel JF, Ullman TA, et al. The management of immunosuppression in patients with inflammatory bowel disease and cancer. Gut. 2013;62:1523-1528.
    • (2013) Gut , vol.62 , pp. 1523-1528
    • Bernheim, O.1    Colombel, J.F.2    Ullman, T.A.3
  • 75
    • 0027412956 scopus 로고
    • The effect of immunosuppression on pre-existing cancers
    • Penn I. The effect of immunosuppression on pre-existing cancers. Transplantation. 1993;55:742.
    • (1993) Transplantation , vol.55
    • Penn, I.1
  • 76
    • 77955479672 scopus 로고    scopus 로고
    • Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT
    • Strangfeld A, Hierse F, Rau R, et al. Risk of incident or recurrent malignancies among patients with rheumatoid arthritis exposed to biologic therapy in the German biologics register RABBIT. Arthritis Res Ther. 2010;12:R5.
    • (2010) Arthritis Res Ther , vol.12 , pp. R5
    • Strangfeld, A.1    Hierse, F.2    Rau, R.3
  • 77
    • 77953103015 scopus 로고    scopus 로고
    • Influence of anti-tumor necrosis factor therapy on cancer incidence in patients with rheumatoid arthritis who have had a prior malignancy: Results from the British Society for Rheumatology Biologics Register
    • Dixon WG, Watson KD, Lunt M, et al. Influence of anti-tumor necrosis factor therapy on cancer incidence in patients with rheumatoid arthritis who have had a prior malignancy: results from the British Society for Rheumatology Biologics Register. Arthritis Care Res. 2010;62:755-763.
    • (2010) Arthritis Care Res , vol.62 , pp. 755-763
    • Dixon, W.G.1    Watson, K.D.2    Lunt, M.3
  • 78
    • 84902145944 scopus 로고    scopus 로고
    • Stopping, continuing, or restarting immunomodulators and biologics when an infection or malignancy develops
    • Swoger JM, Regueiro M. Stopping, continuing, or restarting immunomodulators and biologics when an infection or malignancy develops. Inflamm Bowel Dis. 2014;20:926-935.
    • (2014) Inflamm Bowel Dis , vol.20 , pp. 926-935
    • Swoger, J.M.1    Regueiro, M.2
  • 79
    • 84905581315 scopus 로고    scopus 로고
    • Risk of new or recurrent cancer under immunosuppressive therapy in patients with IBD and previous cancer
    • Beaugerie L, Carrat F, Colobmel JF, et al. Risk of new or recurrent cancer under immunosuppressive therapy in patients with IBD and previous cancer. Gut. 2014;63:1416-1423.
    • (2014) Gut , vol.63 , pp. 1416-1423
    • Beaugerie, L.1    Carrat, F.2    Colobmel, J.F.3
  • 81
    • 74049124863 scopus 로고    scopus 로고
    • World Gastroenterology Organization Practice Guidelines for diagnosis and management of IBD in 2010
    • Bernstein CN, Fried M, Krabshuis JH, et al. World Gastroenterology Organization Practice Guidelines for diagnosis and management of IBD in 2010. Inflamm Bowel Dis. 2010;16:112-124.
    • (2010) Inflamm Bowel Dis , vol.16 , pp. 112-124
    • Bernstein, C.N.1    Fried, M.2    Krabshuis, J.H.3
  • 82
    • 75149161836 scopus 로고    scopus 로고
    • The second European evidence-based consensus on the diagnosis and management of Crohn's disease: Current management
    • Dignass A, Van Assche G, Lindsay JO, et al. The second European evidence-based consensus on the diagnosis and management of Crohn's disease: current management. J Crohns Colitis. 2010;4:28-62.
    • (2010) J Crohns Colitis , vol.4 , pp. 28-62
    • Dignass, A.1    Van Assche, G.2    Lindsay, J.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.