RUNX3 promoter hypermethylation is frequent in leukaemia cell lines and associated with acute myeloid leukaemia inv(16) subtype

British Journal of Haematology

Volumn 169, Issue 3, 2015, Pages 344-351

  Estécio, Marcos R H ^a   Maddipoti, Sirisha ^a   Bueso Ramos, Carlos ^a   Dinardo, Courtney D ^a   Yang, Hui ^a   Wei, Yue ^a   Kondo, Kimie ^a   Fang, Zhihong ^a   Stevenson, William ^b   Chang, Kun Sang ^a   Pierce, Sherry A ^a   Bohannan, Zachary ^a   Borthakur, Gautam ^a   Kantarjian, Hagop ^a   Garcia Manero, Guillermo ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

RUNX3; Acute myeloid leukaemia; DNA methylation; Gene expression; Inv(16)(p13.1q22)

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; MESSENGER RNA; TRANSCRIPTION FACTOR RUNX3; AZACITIDINE; DECITABINE;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CANCER SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA METHYLATION; GENE EXPRESSION; GENE FREQUENCY; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PYROSEQUENCING; RECURRENCE FREE SURVIVAL; RUNX3 GENE; ADULT; AGED; ANALOGS AND DERIVATIVES; CHROMOSOME INVERSION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA, MYELOID, ACUTE; METABOLISM; MIDDLE AGED; MORTALITY; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ADULT; AGED; AZACITIDINE; CELL LINE, TUMOR; CHROMOSOME INVERSION; CORE BINDING FACTOR ALPHA 3 SUBUNIT; DNA METHYLATION; GENE EXPRESSION REGULATION, LEUKEMIC; HUMANS; LEUKEMIA, MYELOID, ACUTE; MIDDLE AGED; PROMOTER REGIONS, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84927696358     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.13299     Document Type: Article

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