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Volumn 82, Issue 1, 2015, Pages 142-146

The acylated (AG) to unacylated (UAG) ghrelin ratio in esterase inhibitor-treated blood is higher than previously described

Author keywords

[No Author keywords available]

Indexed keywords

4 (2 AMINOETHYL)BENZENESULPHONYL FLUORIDE; ESTERASE INHIBITOR; GHRELIN; UNCLASSIFIED DRUG; ENZYME INHIBITOR; ESTERASE;

EID: 84927673595     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12489     Document Type: Article
Times cited : (44)

References (22)
  • 1
    • 2942528459 scopus 로고    scopus 로고
    • Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin
    • van der Lely, A.J., Tschöp, M., Heiman, M.L. et al. (2004) Biological, physiological, pathophysiological, and pharmacological aspects of ghrelin. Endocrine Reviews, 25, 426-457.
    • (2004) Endocrine Reviews , vol.25 , pp. 426-457
    • Van Der Lely, A.J.1    Tschöp, M.2    Heiman, M.L.3
  • 2
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M., Hosoda, H., Date, Y. et al. (1999) Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature, 402, 656-660.
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1    Hosoda, H.2    Date, Y.3
  • 3
    • 79960333463 scopus 로고    scopus 로고
    • Ghrelin and glucose homeostasis
    • Delhanty, P.J. & van der Lely, A.J. (2011) Ghrelin and glucose homeostasis. Peptides, 32, 2309-2318.
    • (2011) Peptides , vol.32 , pp. 2309-2318
    • Delhanty, P.J.1    Van Der Lely, A.J.2
  • 6
    • 84902603186 scopus 로고    scopus 로고
    • Does des-acyl ghrelin improve glycemic control in obese diabetic subjects by decreasing acylated ghrelin levels?
    • Ozcan, B., Neggers, S.J., Miller, A.R. et al. (2013) Does des-acyl ghrelin improve glycemic control in obese diabetic subjects by decreasing acylated ghrelin levels? European Journal of Endocrinology, 170, 799-807.
    • (2013) European Journal of Endocrinology , vol.170 , pp. 799-807
    • Ozcan, B.1    Neggers, S.J.2    Miller, A.R.3
  • 7
    • 0034731310 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin: Two major forms of rat ghrelin peptide in gastrointestinal tissue
    • Hosoda, H., Kojima, M., Matsuo, H. et al. (2000) Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochemical and Biophysical Research Communications, 279, 909-913.
    • (2000) Biochemical and Biophysical Research Communications , vol.279 , pp. 909-913
    • Hosoda, H.1    Kojima, M.2    Matsuo, H.3
  • 8
    • 2942666142 scopus 로고    scopus 로고
    • Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans
    • Broglio, F., Gottero, C., Prodam, F. et al. (2004) Non-acylated ghrelin counteracts the metabolic but not the neuroendocrine response to acylated ghrelin in humans. Journal of Clinical Endocrinology and Metabolism, 89, 3062-3065.
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 3062-3065
    • Broglio, F.1    Gottero, C.2    Prodam, F.3
  • 9
    • 43249089526 scopus 로고    scopus 로고
    • Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men
    • Liu, J., Prudom, C.E., Nass, R. et al. (2008) Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. Journal of Clinical Endocrinology and Metabolism, 93, 1980-1987.
    • (2008) Journal of Clinical Endocrinology and Metabolism , vol.93 , pp. 1980-1987
    • Liu, J.1    Prudom, C.E.2    Nass, R.3
  • 10
    • 77952764514 scopus 로고    scopus 로고
    • Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels
    • Prudom, C., Liu, J., Patrie, J. et al. (2010) Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels. Journal of Clinical Endocrinology and Metabolism, 95, 2351-2358.
    • (2010) Journal of Clinical Endocrinology and Metabolism , vol.95 , pp. 2351-2358
    • Prudom, C.1    Liu, J.2    Patrie, J.3
  • 11
    • 9244225118 scopus 로고    scopus 로고
    • Ghrelin degradation by serum and tissue homogenates: Identification of the cleavage sites
    • De Vriese, C., Gregoire, F., Lema-Kisoka, R. et al. (2004) Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites. Endocrinology, 145, 4997-5005.
    • (2004) Endocrinology , vol.145 , pp. 4997-5005
    • De Vriese, C.1    Gregoire, F.2    Lema-Kisoka, R.3
  • 14
    • 79851485319 scopus 로고    scopus 로고
    • A practical guide for the stabilization of acylghrelin in human blood collections
    • Blatnik, M. & Soderstrom, C.I. (2011) A practical guide for the stabilization of acylghrelin in human blood collections. Clinical Endocrinology, 74, 325-331.
    • (2011) Clinical Endocrinology , vol.74 , pp. 325-331
    • Blatnik, M.1    Soderstrom, C.I.2
  • 16
    • 70450207089 scopus 로고    scopus 로고
    • Unacylated ghrelin (UAG) Enhances the Early Insulin Response to Meal, Improves Glucose Metabolism and Decrease Free Fatty Acids Levels in Healthy Volunteers
    • Presented at the
    • Broglio, F., Prodam, F., Riganti, F. et al. (2007) Unacylated ghrelin (UAG) Enhances the Early Insulin Response to Meal, Improves Glucose Metabolism and Decrease Free Fatty Acids Levels in Healthy Volunteers. Presented at the Annual Meeting of the Endocrine Society, Toronto. Endocrine Abstracts 14, p79.
    • (2007) Annual Meeting of the Endocrine Society, Toronto. Endocrine Abstracts , vol.14 , pp. 79
    • Broglio, F.1    Prodam, F.2    Riganti, F.3
  • 17
    • 6344291317 scopus 로고    scopus 로고
    • Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity
    • Gauna, C., Meyler, F.M., Janssen, J.A. et al. (2004) Administration of acylated ghrelin reduces insulin sensitivity, whereas the combination of acylated plus unacylated ghrelin strongly improves insulin sensitivity. Journal of Clinical Endocrinology and Metabolism, 89, 5035-5042.
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , pp. 5035-5042
    • Gauna, C.1    Meyler, F.M.2    Janssen, J.A.3
  • 18
    • 84869404017 scopus 로고    scopus 로고
    • Prandial ghrelin attenuation provides evidence that des-acyl ghrelin may be an artifact of sample handling in human plasma
    • Blatnik, M., Soderstrom, C.I., Dysinger, M. et al. (2012) Prandial ghrelin attenuation provides evidence that des-acyl ghrelin may be an artifact of sample handling in human plasma. Bioanalysis, 4, 2447-2455.
    • (2012) Bioanalysis , vol.4 , pp. 2447-2455
    • Blatnik, M.1    Soderstrom, C.I.2    Dysinger, M.3
  • 19
    • 84855297943 scopus 로고    scopus 로고
    • Pitfalls in the determination of human acylated ghrelin plasma concentrations using a double antibody enzyme immunometric assay
    • Trivedi, A., Babic, S. & Chanoine, J.P. (2011) Pitfalls in the determination of human acylated ghrelin plasma concentrations using a double antibody enzyme immunometric assay. Clinical Biochemistry, 45, 178-180.
    • (2011) Clinical Biochemistry , vol.45 , pp. 178-180
    • Trivedi, A.1    Babic, S.2    Chanoine, J.P.3
  • 20
    • 84893740040 scopus 로고    scopus 로고
    • Age-dependent decline in acyl-ghrelin concentrations and reduced association of acylghrelin and growth hormone in healthy older adults
    • Nass, R., Farhy, L.S., Liu, J. et al. (2013) Age-dependent decline in acyl-ghrelin concentrations and reduced association of acylghrelin and growth hormone in healthy older adults. Journal of Clinical Endocrinology and Metabolism, 99, 602-608.
    • (2013) Journal of Clinical Endocrinology and Metabolism , vol.99 , pp. 602-608
    • Nass, R.1    Farhy, L.S.2    Liu, J.3
  • 21
    • 35348979155 scopus 로고    scopus 로고
    • Relationships between desacylated and acylated ghrelin and insulin sensitivity in the metabolic syndrome
    • Barazzoni, R., Zanetti, M., Ferreira, C. et al. (2007) Relationships between desacylated and acylated ghrelin and insulin sensitivity in the metabolic syndrome. Journal of Clinical Endocrinology and Metabolism, 92, 3935-3940.
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , pp. 3935-3940
    • Barazzoni, R.1    Zanetti, M.2    Ferreira, C.3
  • 22
    • 33846034095 scopus 로고    scopus 로고
    • Association of acylated and nonacylated ghrelin with insulin sensitivity in overweight and obese postmenopausal women
    • St-Pierre, D.H., Karelis, A.D., Coderre, L. et al. (2007) Association of acylated and nonacylated ghrelin with insulin sensitivity in overweight and obese postmenopausal women. Journal of Clinical Endocrinology and Metabolism, 92, 264-269.
    • (2007) Journal of Clinical Endocrinology and Metabolism , vol.92 , pp. 264-269
    • St-Pierre, D.H.1    Karelis, A.D.2    Coderre, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.