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Volumn 36, Issue 4, 2014, Pages 498-507

All-trans retinoic acid downregulates ALDH1-mediated stemness and inhibits tumour formation in ovarian cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; BIOLOGICAL MARKER; NOTCH1 RECEPTOR; PROTEIN FOXM1; RETINOIC ACID; THIOSTREPTON; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DIPEPTIDE; FORKHEAD TRANSCRIPTION FACTOR; FOXM1 PROTEIN, HUMAN; ISOENZYME; N-(N-(3,5-DIFLUOROPHENACETYL)ALANYL)PHENYLGLYCINE TERT-BUTYL ESTER; NOTCH1 PROTEIN, HUMAN; RETINAL DEHYDROGENASE; SMALL INTERFERING RNA;

EID: 84927644916     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv018     Document Type: Article
Times cited : (61)

References (50)
  • 1
    • 84855792427 scopus 로고    scopus 로고
    • Cancer statistics, 2012
    • Siegel, R. et al. (2012) Cancer statistics, 2012. CA Cancer J. Clin., 62, 10-29.
    • (2012) CA Cancer J. Clin , vol.62 , pp. 10-29
    • Siegel, R.1
  • 2
    • 84899861747 scopus 로고    scopus 로고
    • Circulating IGF system and treatment outcome in epithelial ovarian cancer
    • Huang, Y.F. et al. (2014) Circulating IGF system and treatment outcome in epithelial ovarian cancer. Endocr. Relat. Cancer, 21, 217-229.
    • (2014) Endocr. Relat. Cancer , vol.21 , pp. 217-229
    • Huang, Y.F.1
  • 3
    • 66149083645 scopus 로고    scopus 로고
    • Ovarian cancer
    • Cho, K.R. et al. (2009) Ovarian cancer. Annu. Rev. Pathol., 4, 287-313.
    • (2009) Annu. Rev. Pathol , vol.4 , pp. 287-313
    • Cho, K.R.1
  • 4
    • 49249091523 scopus 로고    scopus 로고
    • Identification and characterization of ovarian cancer-initiating cells from primary human tumors
    • Zhang, S. et al. (2008) Identification and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res., 68, 4311-4320.
    • (2008) Cancer Res , vol.68 , pp. 4311-4320
    • Zhang, S.1
  • 5
    • 78649960144 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling
    • Sullivan, J.P. et al. (2010) Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling. Cancer Res., 70, 9937-9948.
    • (2010) Cancer Res , vol.70 , pp. 9937-9948
    • Sullivan, J.P.1
  • 6
    • 80051621163 scopus 로고    scopus 로고
    • γ-Secretase Inhibitor, DAPT Inhibits Self-renewal and Stemness Maintenance of Ovarian Cancer Stem-like Cells In Vitro
    • Jiang, L.Y. et al. (2011) γ-Secretase Inhibitor, DAPT Inhibits Self-renewal and Stemness Maintenance of Ovarian Cancer Stem-like Cells In Vitro. Chin. J. Cancer Res., 23, 140-146.
    • (2011) Chin. J. Cancer Res , vol.23 , pp. 140-146
    • Jiang, L.Y.1
  • 7
    • 77953700950 scopus 로고    scopus 로고
    • Targeting Notch to target cancer stem cells
    • Pannuti, A. et al. (2010) Targeting Notch to target cancer stem cells. Clin. Cancer Res., 16, 3141-3152.
    • (2010) Clin. Cancer Res , vol.16 , pp. 3141-3152
    • Pannuti, A.1
  • 8
    • 35848955428 scopus 로고    scopus 로고
    • ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
    • Ginestier, C. et al. (2007) ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell, 1, 555-567.
    • (2007) Cell Stem Cell , vol.1 , pp. 555-567
    • Ginestier, C.1
  • 9
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang, E.H. et al. (2009) Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res., 69, 3382-3389.
    • (2009) Cancer Res , vol.69 , pp. 3382-3389
    • Huang, E.H.1
  • 10
    • 70350247558 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer
    • Carpentino, J.E. et al. (2009) Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer. Cancer Res., 69, 8208-8215.
    • (2009) Cancer Res , vol.69 , pp. 8208-8215
    • Carpentino, J.E.1
  • 11
    • 77953288958 scopus 로고    scopus 로고
    • ALDH high adenoid cystic carcinoma cells display cancer stem cell properties and are responsible for mediating metastasis
    • Sun, S. et al. (2010) ALDH high adenoid cystic carcinoma cells display cancer stem cell properties and are responsible for mediating metastasis. Biochem. Biophys. Res. Commun., 396, 843-848.
    • (2010) Biochem. Biophys. Res. Commun , vol.396 , pp. 843-848
    • Sun, S.1
  • 12
    • 77953789724 scopus 로고    scopus 로고
    • High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer
    • van den Hoogen, C. et al. (2010) High aldehyde dehydrogenase activity identifies tumor-initiating and metastasis-initiating cells in human prostate cancer. Cancer Res., 70, 5163-5173.
    • (2010) Cancer Res , vol.70 , pp. 5163-5173
    • van den Hoogen, C.1
  • 13
    • 84884497621 scopus 로고    scopus 로고
    • A2780 human ovarian cancer cells with acquired paclitaxel resistance display cancer stem cell properties
    • Han, X. et al. (2013) A2780 human ovarian cancer cells with acquired paclitaxel resistance display cancer stem cell properties. Oncol. Lett., 6, 1295-1298.
    • (2013) Oncol. Lett , vol.6 , pp. 1295-1298
    • Han, X.1
  • 14
    • 84880333428 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1/epidermal growth factor receptor coexpression is characteristic of a highly aggressive, poor-prognosis subgroup of high-grade serous ovarian carcinoma
    • Liebscher, C.A. et al. (2013) Aldehyde dehydrogenase 1/epidermal growth factor receptor coexpression is characteristic of a highly aggressive, poor-prognosis subgroup of high-grade serous ovarian carcinoma. Hum. Pathol., 44, 1465-1471.
    • (2013) Hum. Pathol , vol.44 , pp. 1465-1471
    • Liebscher, C.A.1
  • 15
    • 84863162778 scopus 로고    scopus 로고
    • ALDH1-bright epithelial ovarian cancer cells are associated with CD44 expression, drug resistance, and poor clinical outcome
    • Wang, Y.C. et al. (2012) ALDH1-bright epithelial ovarian cancer cells are associated with CD44 expression, drug resistance, and poor clinical outcome. Am. J. Pathol., 180, 1159-1169.
    • (2012) Am. J. Pathol , vol.180 , pp. 1159-1169
    • Wang, Y.C.1
  • 16
    • 77956302698 scopus 로고    scopus 로고
    • Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers
    • Deng, S. et al. (2010) Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers. PLoS One, 5, e10277.
    • (2010) PLoS One , vol.5
    • Deng, S.1
  • 17
    • 84878804228 scopus 로고    scopus 로고
    • ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis
    • Kuroda, T. et al. (2013) ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis. PLoS One, 8, e65158.
    • (2013) PLoS One , vol.8
    • Kuroda, T.1
  • 18
    • 67349255442 scopus 로고    scopus 로고
    • ALDH1 expression correlates with favorable prognosis in ovarian cancers
    • Chang, B. et al. (2009) ALDH1 expression correlates with favorable prognosis in ovarian cancers. Mod. Pathol., 22, 817-823.
    • (2009) Mod. Pathol , vol.22 , pp. 817-823
    • Chang, B.1
  • 19
    • 84894257177 scopus 로고    scopus 로고
    • Prognostic value of cancer stem cell marker aldehyde dehydrogenase in ovarian cancer: a meta-analysis
    • Liu, S. et al. (2013) Prognostic value of cancer stem cell marker aldehyde dehydrogenase in ovarian cancer: a meta-analysis. PLoS One, 8, e81050.
    • (2013) PLoS One , vol.8
    • Liu, S.1
  • 20
    • 84865558583 scopus 로고    scopus 로고
    • Overcoming challenges of ovarian cancer stem cells: novel therapeutic approaches
    • Aguilar-Gallardo, C. et al. (2012) Overcoming challenges of ovarian cancer stem cells: novel therapeutic approaches. Stem Cell Rev., 8, 994-1010.
    • (2012) Stem Cell Rev , vol.8 , pp. 994-1010
    • Aguilar-Gallardo, C.1
  • 21
    • 84927599450 scopus 로고    scopus 로고
    • Therapeutic Targeting of Cancer Stem Cells
    • De Maria, R. et al. (2011) Therapeutic Targeting of Cancer Stem Cells. Front Oncol. 17, 1-10.
    • (2011) Front Oncol , vol.17 , pp. 1-10
    • De Maria, R.1
  • 22
    • 84896289524 scopus 로고    scopus 로고
    • Differentiation therapy for solid tumors
    • Xu, W.P. et al. (2014) Differentiation therapy for solid tumors. J. Dig. Dis., 15, 159-165.
    • (2014) J. Dig. Dis , vol.15 , pp. 159-165
    • Xu, W.P.1
  • 23
    • 84885190180 scopus 로고    scopus 로고
    • Effect of all-trans retinoic acid on the differentiation of U87 glioma stem/progenitor cells
    • Shi, Z. et al. (2013) Effect of all-trans retinoic acid on the differentiation of U87 glioma stem/progenitor cells. Cell. Mol. Neurobiol., 33, 943-951.
    • (2013) Cell. Mol. Neurobiol , vol.33 , pp. 943-951
    • Shi, Z.1
  • 24
    • 77952329017 scopus 로고    scopus 로고
    • Differentiation therapy exerts antitumor effects on stem-like glioma cells
    • Campos, B. et al. (2010) Differentiation therapy exerts antitumor effects on stem-like glioma cells. Clin. Cancer Res., 16, 2715-2728.
    • (2010) Clin. Cancer Res , vol.16 , pp. 2715-2728
    • Campos, B.1
  • 25
    • 84868203536 scopus 로고    scopus 로고
    • All-trans-retinoic acid inhibits growth of head and neck cancer stem cells by suppression of Wnt/β-catenin pathway
    • Lim, Y.C. et al. (2012) All-trans-retinoic acid inhibits growth of head and neck cancer stem cells by suppression of Wnt/β-catenin pathway. Eur. J. Cancer, 48, 3310-3318.
    • (2012) Eur. J. Cancer , vol.48 , pp. 3310-3318
    • Lim, Y.C.1
  • 26
    • 70350244836 scopus 로고    scopus 로고
    • Retinoid signaling regulates breast cancer stem cell differentiation
    • Ginestier, C. et al. (2009) Retinoid signaling regulates breast cancer stem cell differentiation. Cell Cycle, 8, 3297-3302.
    • (2009) Cell Cycle , vol.8 , pp. 3297-3302
    • Ginestier, C.1
  • 27
    • 84858332297 scopus 로고    scopus 로고
    • The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells
    • Whitworth, J.M. et al. (2012) The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells. Gynecol. Oncol., 125, 226-230.
    • (2012) Gynecol. Oncol , vol.125 , pp. 226-230
    • Whitworth, J.M.1
  • 28
    • 79959957800 scopus 로고    scopus 로고
    • Combination of paclitaxel-and retinoic acidincorporated nanoparticles for the treatment of CT-26 colon carcinoma
    • Hong, G.Y. et al. (2011) Combination of paclitaxel-and retinoic acidincorporated nanoparticles for the treatment of CT-26 colon carcinoma. Arch. Pharm. Res., 34, 407-417.
    • (2011) Arch. Pharm. Res , vol.34 , pp. 407-417
    • Hong, G.Y.1
  • 29
    • 84900768251 scopus 로고    scopus 로고
    • A new nanostructured carrier design including oil to enhance the pharmaceutical properties of retinoid therapy and its therapeutic effects on chemo-resistant ovarian cancer
    • Narvekar, M. et al. (2014) A new nanostructured carrier design including oil to enhance the pharmaceutical properties of retinoid therapy and its therapeutic effects on chemo-resistant ovarian cancer. Eur. J. Pharm. Biopharm., 88, 226-237.
    • (2014) Eur. J. Pharm. Biopharm , vol.88 , pp. 226-237
    • Narvekar, M.1
  • 30
    • 57249109899 scopus 로고    scopus 로고
    • Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction
    • Elizondo, G. et al. (2009) Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction. Biochem. Pharmacol., 77, 248-257.
    • (2009) Biochem. Pharmacol , vol.77 , pp. 248-257
    • Elizondo, G.1
  • 31
    • 11844285668 scopus 로고    scopus 로고
    • Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde
    • Moreb, J.S. et al. (2005) Retinoic acid down-regulates aldehyde dehydrogenase and increases cytotoxicity of 4-hydroperoxycyclophosphamide and acetaldehyde. J. Pharmacol. Exp. Ther., 312, 339-345.
    • (2005) J. Pharmacol. Exp. Ther , vol.312 , pp. 339-345
    • Moreb, J.S.1
  • 32
    • 0026017234 scopus 로고
    • Human ovarian cancer xenografts in nude mice: characterization and analysis of antigen expression
    • Molthoff, C.F. et al. (1991) Human ovarian cancer xenografts in nude mice: characterization and analysis of antigen expression. Int. J. Cancer, 47, 72-79.
    • (1991) Int. J. Cancer , vol.47 , pp. 72-79
    • Molthoff, C.F.1
  • 33
    • 84864413214 scopus 로고    scopus 로고
    • Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures
    • Saw, Y.T. et al. (2012) Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures. BMC Cancer, 12, 329.
    • (2012) BMC Cancer , vol.12 , pp. 329
    • Saw, Y.T.1
  • 34
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • 33
    • Bell, D. et al. (2011) Integrated genomic analyses of ovarian carcinoma. Nature. 474, 609-615.33.
    • (2011) Nature , vol.474 , pp. 609-615
    • Bell, D.1
  • 35
    • 80255137100 scopus 로고    scopus 로고
    • Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells
    • Kryczek, I. et al. (2012) Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells. Int. J. Cancer, 130, 29-39.
    • (2012) Int. J. Cancer , vol.130 , pp. 29-39
    • Kryczek, I.1
  • 36
    • 84874644333 scopus 로고    scopus 로고
    • Ovarian cancer stem cells: a new target for cancer therapy
    • 916819
    • Zhan, Q. et al. (2013) Ovarian cancer stem cells: a new target for cancer therapy. Biomed Res. Int., 2013, 916819.
    • (2013) Biomed Res. Int , vol.2013
    • Zhan, Q.1
  • 37
    • 78650455641 scopus 로고    scopus 로고
    • Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer
    • Landen, C.N. Jr et al. (2010) Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancer. Mol. Cancer Ther., 9, 3186-3199.
    • (2010) Mol. Cancer Ther , vol.9 , pp. 3186-3199
    • Landen, C.N.1
  • 38
    • 77950614776 scopus 로고    scopus 로고
    • Forkhead box M1 transcription factor: a novel target for cancer therapy
    • Wang, Z. et al. (2010) Forkhead box M1 transcription factor: a novel target for cancer therapy. Cancer Treat. Rev., 36, 151-156.
    • (2010) Cancer Treat. Rev , vol.36 , pp. 151-156
    • Wang, Z.1
  • 39
    • 81055137232 scopus 로고    scopus 로고
    • FOXM1: from cancer initiation to progression and treatment
    • Koo, C.Y. et al. (2012) FOXM1: from cancer initiation to progression and treatment. Biochim. Biophys. Acta, 1819, 28-37.
    • (2012) Biochim. Biophys. Acta , vol.1819 , pp. 28-37
    • Koo, C.Y.1
  • 40
    • 11144280578 scopus 로고    scopus 로고
    • Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data
    • Pilarsky, C. et al. (2004) Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia, 6, 744-750.
    • (2004) Neoplasia , vol.6 , pp. 744-750
    • Pilarsky, C.1
  • 41
    • 79951831756 scopus 로고    scopus 로고
    • Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy
    • Uddin, S. et al. (2011) Genome-wide expression analysis of Middle Eastern colorectal cancer reveals FOXM1 as a novel target for cancer therapy. Am. J. Pathol., 178, 537-547.
    • (2011) Am. J. Pathol , vol.178 , pp. 537-547
    • Uddin, S.1
  • 42
    • 84872137211 scopus 로고    scopus 로고
    • FoxM1 expression is significantly associated with cisplatin-based chemotherapy resistance and poor prognosis in advanced non-small cell lung cancer patients
    • Wang, Y. et al. (2013) FoxM1 expression is significantly associated with cisplatin-based chemotherapy resistance and poor prognosis in advanced non-small cell lung cancer patients. Lung Cancer, 79, 173-179.
    • (2013) Lung Cancer , vol.79 , pp. 173-179
    • Wang, Y.1
  • 43
    • 78549285678 scopus 로고    scopus 로고
    • Induction of human epithelial stem/progenitor expansion by FOXM1
    • Gemenetzidis, E. et al. (2010) Induction of human epithelial stem/progenitor expansion by FOXM1. Cancer Res., 70, 9515-9526.
    • (2010) Cancer Res , vol.70 , pp. 9515-9526
    • Gemenetzidis, E.1
  • 44
    • 78650475564 scopus 로고    scopus 로고
    • Foxm1 transcription factor is required for maintenance of pluripotency of P19 embryonal carcinoma cells
    • Xie, Z. et al. (2010) Foxm1 transcription factor is required for maintenance of pluripotency of P19 embryonal carcinoma cells. Nucleic Acids Res., 38, 8027-8038.
    • (2010) Nucleic Acids Res , vol.38 , pp. 8027-8038
    • Xie, Z.1
  • 45
    • 84869210716 scopus 로고    scopus 로고
    • FoxM1 and Wnt/beta-catenin signaling in glioma stem cells
    • Gong, A, et al. (2012) FoxM1 and Wnt/beta-catenin signaling in glioma stem cells. Cancer Res. 72,5658-5662.
    • (2012) Cancer Res , vol.72 , pp. 5658-5662
    • Gong, A.1
  • 46
    • 78651333282 scopus 로고    scopus 로고
    • Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells
    • Wang, Z. et al. (2011) Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. J. Cell. Biochem., 112, 78-88.
    • (2011) J. Cell. Biochem , vol.112 , pp. 78-88
    • Wang, Z.1
  • 47
    • 79955025420 scopus 로고    scopus 로고
    • The role of human aldehyde dehydrogenase in normal and cancer stem cells
    • Ma, I. et al. (2011) The role of human aldehyde dehydrogenase in normal and cancer stem cells. Stem Cell Rev., 7, 292-306.
    • (2011) Stem Cell Rev , vol.7 , pp. 292-306
    • Ma, I.1
  • 48
    • 78649668597 scopus 로고    scopus 로고
    • Retinoids, retinoic acid receptors, and cancer
    • Tang, X.H. et al. (2011) Retinoids, retinoic acid receptors, and cancer. Annu. Rev. Pathol., 6, 345-364.
    • (2011) Annu. Rev. Pathol , vol.6 , pp. 345-364
    • Tang, X.H.1
  • 49
    • 84867951956 scopus 로고    scopus 로고
    • All-trans retinoic acid in the treatment of pediatric acute promyelocytic leukemia
    • Masetti, R. et al. (2012) All-trans retinoic acid in the treatment of pediatric acute promyelocytic leukemia. Expert Rev. Anticancer Ther., 12, 1191-1204.
    • (2012) Expert Rev. Anticancer Ther , vol.12 , pp. 1191-1204
    • Masetti, R.1


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