γ-Secretase inhibitor, DAPT inhibits self-renewal and stemness maintenance of ovarian cancer stem-like cells in vitro

Chinese Journal of Cancer Research

Volumn 23, Issue 2, 2011, Pages 140-146

  Jiang, Li Yu ^a   Zhang, Xiao Lei ^a   Du, Ping ^a   Zheng, Jian Hua ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Notch signaling pathwa; Ovarian cancer stem cells (OCSCs); Y secretase inhibitor

Indexed keywords

ANTINEOPLASTIC AGENT; CD133 ANTIGEN; GAMMA SECRETASE INHIBITOR; HERMES ANTIGEN; MESSENGER RNA; N [N (3,5 DIFLUOROPHENACETYL)LEVO ALANYL] S PHENYLGLYCINE TERT BUTYL ESTER; NOTCH INTRACELLULAR DOMAIN PROTEIN; NOTCH RECEPTOR; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN; STEM CELL FACTOR RECEPTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER STEM CELL; CELL ASSAY; CONTROLLED STUDY; DOWN REGULATION; DRUG SCREENING; FEMALE; HUMAN; HUMAN CELL; OVARY CANCER; OVARY CANCER STEM CELL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 80051621163     PISSN: 10009604     EISSN: 19930631     Source Type: Journal    
DOI: 10.1007/s11670-011-0140-1     Document Type: Article

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