-
2
-
-
84861719757
-
Patient-derived tumour xenografts as models for oncology drug development
-
Tentler JJ, Tan AC, Weekes CD, et al. Patient-derived tumour xenografts as models for oncology drug development. Nat Rev Clin Oncol 2012; 9:338-350.
-
(2012)
Nat Rev Clin Oncol
, vol.9
, pp. 338-350
-
-
Tentler, J.J.1
Tan, A.C.2
Weekes, C.D.3
-
3
-
-
33645734205
-
Contributions of human tumor xenografts to anticancer drug development
-
Sausville EA, Burger AM. Contributions of human tumor xenografts to anticancer drug development. Cancer Res 2006; 66:3351-3354.
-
(2006)
Cancer Res
, vol.66
, pp. 3351-3354
-
-
Sausville, E.A.1
Burger, A.M.2
-
4
-
-
0141566685
-
Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models
-
Voskoglou-Nomikos T, Pater JL, Seymour L. Clinical predictive value of the in vitro cell line, human xenograft, and mouse allograft preclinical cancer models. Clin Cancer Res 2003; 9:4227-4239.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4227-4239
-
-
Voskoglou-Nomikos, T.1
Pater, J.L.2
Seymour, L.3
-
5
-
-
84906895091
-
Patient derived xenograft models: An emerging platform for translational cancer research
-
[ Epub ahead of print]
-
Hidalgo M, Amant F, Biankin AV, et al. Patient derived xenograft models: an emerging platform for translational cancer research. Cancer Dis 2014. [Epub ahead of print]
-
(2014)
Cancer Dis
-
-
Hidalgo, M.1
Amant, F.2
Biankin, A.V.3
-
6
-
-
81755163602
-
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anticancer drug resistance
-
Gillet JP, Calcagno AM, Varma S, et al. Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anticancer drug resistance. Proc Natl Acad Sci U S A 2011; 108:18708-18713.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18708-18713
-
-
Gillet, J.P.1
Calcagno, A.M.2
Varma, S.3
-
8
-
-
0005032442
-
Successful subcutaneous growth and transplantation of human tumors in X-irradiated laboratory animals
-
Toolan HW. Successful subcutaneous growth and transplantation of human tumors in X-irradiated laboratory animals. Proc Soc Exp Biol Med 1951; 77:572-578.
-
(1951)
Proc Soc Exp Biol Med
, vol.77
, pp. 572-578
-
-
Toolan, H.W.1
-
9
-
-
0013977818
-
Nude', a new hairless gene with pleiotropic effects in the mouse
-
Flanagan SP. 'Nude', a new hairless gene with pleiotropic effects in the mouse. Genet Res 1966; 8:295-309.
-
(1966)
Genet Res
, vol.8
, pp. 295-309
-
-
Flanagan S.P.'.1
-
10
-
-
0014649888
-
Heterotransplantation of a human malignant tumour to 'Nude' mice
-
Rygaard J, Povlsen CO. Heterotransplantation of a human malignant tumour to 'Nude' mice. Acta Pathol Microbiol Scand 1969; 77:758-760.
-
(1969)
Acta Pathol Microbiol Scand
, vol.77
, pp. 758-760
-
-
Rygaard, J.1
Povlsen, C.O.2
-
11
-
-
0019211576
-
Human breast-cancer xenografts in immune-suppressed mice
-
Bailey MJ, Gazet JC, Peckham MJ. Human breast-cancer xenografts in immune-suppressed mice. Br J Cancer 1980; 42:524-529.
-
(1980)
Br J Cancer
, vol.42
, pp. 524-529
-
-
Bailey, M.J.1
Gazet, J.C.2
Peckham, M.J.3
-
12
-
-
0019470320
-
Comparative functional histopathology of human breast carcinoma xenografts
-
Bailey MJ, Ormerod MG, Imrie SF, et al. Comparative functional histopathology of human breast carcinoma xenografts. Br J Cancer 1981; 43:125-134.
-
(1981)
Br J Cancer
, vol.43
, pp. 125-134
-
-
Bailey, M.J.1
Ormerod, M.G.2
Imrie, S.F.3
-
14
-
-
84863722104
-
Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts
-
Cottu P, Marangoni E, Assayag F, et al. Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts. Breast Cancer Res Treat 2012; 133:595-606.
-
(2012)
Breast Cancer Res Treat
, vol.133
, pp. 595-606
-
-
Cottu, P.1
Marangoni, E.2
Assayag, F.3
-
15
-
-
34447123764
-
A new model of patient tumor-derived breast cancer xenografts for preclinical assays
-
Marangoni E, Vincent-Salomon A, Auger N, et al. A new model of patient tumor-derived breast cancer xenografts for preclinical assays. Clin Cancer Res 2007; 13:3989-3998.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 3989-3998
-
-
Marangoni, E.1
Vincent-Salomon, A.2
Auger, N.3
-
16
-
-
84881415504
-
A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models
-
Zhang X, Claerhout S, Prat A, et al. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res 2013; 73:4885-4897.
-
(2013)
Cancer Res
, vol.73
, pp. 4885-4897
-
-
Zhang, X.1
Claerhout, S.2
Prat, A.3
-
17
-
-
81255135837
-
Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
-
DeRose YS, Wang G, Lin YC, et al. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat Med 2011; 17:1514-1520.
-
(2011)
Nat Med
, vol.17
, pp. 1514-1520
-
-
Derose, Y.S.1
Wang, G.2
Lin, Y.C.3
-
18
-
-
84883150182
-
Patient-derived models of human breast cancer: Protocols for in vitro and in vivo applications in tumor biology and translational medicine
-
Chapter 14:Unit14 23
-
DeRose YS, Gligorich KM, Wang G, et al. Patient-derived models of human breast cancer: protocols for in vitro and in vivo applications in tumor biology and translational medicine. Curr Protoc Pharmacol 2013; Chapter 14:Unit14 23.
-
(2013)
Curr Protoc Pharmacol
-
-
Derose, Y.S.1
Gligorich, K.M.2
Wang, G.3
-
19
-
-
84894305985
-
Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse
-
du Manoir S, Orsetti B, Bras-Goncalves R, et al. Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse. Mol Oncol 2014; 8:431-443.
-
(2014)
Mol Oncol
, vol.8
, pp. 431-443
-
-
Du Manoir, S.1
Orsetti, B.2
Bras-Goncalves, R.3
-
20
-
-
84916933882
-
Prolactin-humanized mice: An improved animal recipient for therapy response-testing of patient-derived breast cancer xenotransplants
-
San Antonio: Cancer Research
-
S Rui H, Utama FE, Yanac AF et al. Prolactin-humanized mice: an improved animal recipient for therapy response-testing of patient-derived breast cancer xenotransplants. In: Thirty-Fifth Annual CTRC-AACR San Antonio Breast Cancer Symposium; San Antonio: Cancer Research; 2012.
-
(2012)
Thirty-Fifth Annual CTRC-AACR San Antonio Breast Cancer Symposium
-
-
Rui H, S.1
Utama, F.E.2
Yanac, A.F.3
-
22
-
-
84891278007
-
ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program
-
Charafe-Jauffret E, Ginestier C, Bertucci F, et al. ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program. Cancer Res 2013; 73:7290-7300.
-
(2013)
Cancer Res
, vol.73
, pp. 7290-7300
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Bertucci, F.3
-
23
-
-
84855784479
-
Molecular profiling of patient-derived breast cancer xenografts
-
Reyal F, Guyader C, Decraene C, et al. Molecular profiling of patient-derived breast cancer xenografts. Breast Cancer Res 2012; 14:R11.
-
(2012)
Breast Cancer Res
, vol.14
, pp. R11
-
-
Reyal, F.1
Guyader, C.2
Decraene, C.3
-
24
-
-
70350571374
-
Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models
-
Bergamaschi A, Hjortland GO, Triulzi T, et al. Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models. Mol Oncol 2009; 3:469-482.
-
(2009)
Mol Oncol
, vol.3
, pp. 469-482
-
-
Bergamaschi, A.1
Hjortland, G.O.2
Triulzi, T.3
-
25
-
-
77955523425
-
Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminallike breast cancer xenograft models
-
Moestue SA, Borgan E, Huuse EM, et al. Distinct choline metabolic profiles are associated with differences in gene expression for basal-like and luminallike breast cancer xenograft models. BMC cancer 2010; 10:433.
-
(2010)
BMC Cancer
, vol.10
, pp. 433
-
-
Moestue, S.A.1
Borgan, E.2
Huuse, E.M.3
-
26
-
-
84896709072
-
Interplay of choline metabolites and genes in patient-derived breast cancer xenografts
-
Grinde MT, Skrbo N, Moestue SA, et al. Interplay of choline metabolites and genes in patient-derived breast cancer xenografts. Breast Cancer Res 2014; 16:R5.
-
(2014)
Breast Cancer Res
, vol.16
, pp. R5
-
-
Grinde, M.T.1
Skrbo, N.2
Moestue, S.A.3
-
27
-
-
84867327925
-
Nonsentinel lymph node metastasis prediction in breast cancer with metastatic sentinel lymph node: Impact of molecular subtypes classification
-
Reyal F, Belichard C, Rouzier R, et al. Nonsentinel lymph node metastasis prediction in breast cancer with metastatic sentinel lymph node: impact of molecular subtypes classification. PLoS One 2012; 7:e47390.
-
(2012)
PLoS One
, vol.7
, pp. e47390
-
-
Reyal, F.1
Belichard, C.2
Rouzier, R.3
-
28
-
-
84855482786
-
Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations
-
Kresse SH, Meza-Zepeda LA, Machado I, et al. Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations. Cancer 2012; 118:558-570.
-
(2012)
Cancer
, vol.118
, pp. 558-570
-
-
Kresse, S.H.1
Meza-Zepeda, L.A.2
Machado, I.3
-
29
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding L, Ellis MJ, Li S, et al. Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 2010; 464:999-1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
-
30
-
-
84884559238
-
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts
-
Li S, Shen D, Shao J, et al. Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts. Cell Rep 2013; 4:1116-1130.
-
(2013)
Cell Rep
, vol.4
, pp. 1116-1130
-
-
Li, S.1
Shen, D.2
Shao, J.3
-
31
-
-
84893637270
-
One mouse, one patient paradigm: New avatars of personalized cancer therapy
-
Malaney P, Nicosia SV, Dave V. One mouse, one patient paradigm: new avatars of personalized cancer therapy. Cancer Lett 2014; 344:1-12.
-
(2014)
Cancer Lett
, vol.344
, pp. 1-12
-
-
Malaney, P.1
Nicosia, S.V.2
Dave, V.3
-
32
-
-
84866681744
-
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition
-
Ibrahim YH, Garcia-Garcia C, Serra V, et al. PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA-proficient triple-negative breast cancer to PARP inhibition. Cancer Discov 2012; 2:1036-1047.
-
(2012)
Cancer Discov
, vol.2
, pp. 1036-1047
-
-
Ibrahim, Y.H.1
Garcia-Garcia, C.2
Serra, V.3
-
33
-
-
84874358175
-
Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer
-
Moestue SA, Dam CG, Gorad SS, et al. Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer. Breast Cancer Res 2013; 15:R16.
-
(2013)
Breast Cancer Res
, vol.15
, pp. R16
-
-
Moestue, S.A.1
Dam, C.G.2
Gorad, S.S.3
-
34
-
-
84871385337
-
Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patientderived triple-negative breast cancer xenografts
-
Romanelli A, Clark A, Assayag F, et al. Inhibiting aurora kinases reduces tumor growth and suppresses tumor recurrence after chemotherapy in patientderived triple-negative breast cancer xenografts. Mol Cancer Ther 2012; 11:2693-2703.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 2693-2703
-
-
Romanelli, A.1
Clark, A.2
Assayag, F.3
-
35
-
-
84870372659
-
Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells
-
Qiu M, Peng Q, Jiang I, et al. Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells. Cancer Lett 2013; 328:261-270.
-
(2013)
Cancer Lett
, vol.328
, pp. 261-270
-
-
Qiu, M.1
Peng, Q.2
Jiang, I.3
-
36
-
-
84866557855
-
Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures
-
Kabos P, Finlay-Schultz J, Li C, et al. Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures. Breast Cancer Res Treat 2012; 135:415-432.
-
(2012)
Breast Cancer Res Treat
, vol.135
, pp. 415-432
-
-
Kabos, P.1
Finlay-Schultz, J.2
Li, C.3
-
37
-
-
84876861153
-
Paracrine Wnt signaling both promotes and inhibits human breast tumor growth
-
Green JL, La J, Yum KW, et al. Paracrine Wnt signaling both promotes and inhibits human breast tumor growth. Proc Natl Acad Sci U S A 2013; 110:6991-6996.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 6991-6996
-
-
Green, J.L.1
La Yum J, K.W.2
-
38
-
-
84875168492
-
Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors
-
Schott AF, Landis MD, Dontu G, et al. Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clin Cancer Res 2013; 19:1512-1524.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1512-1524
-
-
Schott, A.F.1
Landis, M.D.2
Dontu, G.3
-
39
-
-
84859726248
-
Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models
-
Ma CX, Cai S, Li S, et al. Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. J Clin Invest 2012; 122:1541-1552.
-
(2012)
J Clin Invest
, vol.122
, pp. 1541-1552
-
-
Ma, C.X.1
Cai, S.2
Li, S.3
-
40
-
-
84873333749
-
Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms
-
Singh JK, Farnie G, Bundred NJ, et al. Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and-independent mechanisms. Clin Cancer Res 2013; 19:643-656.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 643-656
-
-
Singh, J.K.1
Farnie, G.2
Bundred, N.J.3
-
41
-
-
84901465453
-
Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition
-
Zhang H, Cohen AL, Krishnakumar S, et al. Patient-derived xenografts of triple-negative breast cancer reproduce molecular features of patient tumors and respond to mTOR inhibition. Breast Cancer Res 2014; 16:R36.
-
(2014)
Breast Cancer Res
, vol.16
, pp. R36
-
-
Zhang, H.1
Cohen, A.L.2
Krishnakumar, S.3
-
42
-
-
84905993236
-
Acquired resistance to endocrine treatments is associated to tumor-specific molecular changes in patientderived luminal breast cancer xenografts
-
Cottu PH, Bieche I, Assayag F, et al. Acquired resistance to endocrine treatments is associated to tumor-specific molecular changes in patientderived luminal breast cancer xenografts. Clin Can Res 2014; 20:4314-4325.
-
(2014)
Clin Can Res
, vol.20
, pp. 4314-4325
-
-
Cottu, P.H.1
Bieche, I.2
Assayag, F.3
-
43
-
-
84899707234
-
Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment
-
Garralda E, Paz K, Lopez-Casas PP, et al. Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment. Clin Cancer Res 2014; 20:2476-2484.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2476-2484
-
-
Garralda, E.1
Paz, K.2
Lopez-Casas, P.P.3
-
44
-
-
0016233589
-
The growth of human tumours in immunosuppressed mice and their response to chemotherapy
-
Berenbaum MC, Sheard CE, Reittie JR, Bundick RV. The growth of human tumours in immunosuppressed mice and their response to chemotherapy. Br J Cancer 1974; 30:13-32.
-
(1974)
Br J Cancer
, vol.30
, pp. 13-32
-
-
Berenbaum, M.C.1
Sheard, C.E.2
Reittie, J.R.3
Bundick, R.V.4
-
45
-
-
0021682994
-
Limitations of the human tumour xenograft system in individual patient drug sensitivity testing
-
Bailey MJ, Jones AJ, Shorthouse AJ, et al. Limitations of the human tumour xenograft system in individual patient drug sensitivity testing. Br J Cancer 1984; 50:721-724.
-
(1984)
Br J Cancer
, vol.50
, pp. 721-724
-
-
Bailey, M.J.1
Jones, A.J.2
Shorthouse, A.J.3
-
46
-
-
84893792203
-
Individual xenograft as a personalized therapeutic resort for women with metastatic triple-negative breast carcinoma
-
Bousquet G, Feugeas JP, Ferreira I, et al. Individual xenograft as a personalized therapeutic resort for women with metastatic triple-negative breast carcinoma. Breast Cancer Res 2014; 16:401.
-
(2014)
Breast Cancer Res
, vol.16
, pp. 401
-
-
Bousquet, G.1
Feugeas, J.P.2
Ferreira, I.3
|