A vascular patch prepared from thai silk fibroin and gelatin hydrogel incorporating simvastatin-micelles to recruit endothelial progenitor cells

Tissue Engineering - Part A

Volumn 21, Issue 7-8, 2015, Pages 1309-1319

  Thitiwuthikiat, Piyanuch ^a   Ii, Masaaki ^b   Saito, Takashi ^c   Asahi, Michio ^b   Kanokpanont, Sorada ^a   Tabata, Yasuhiko ^c  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b OSAKA MEDICAL COLLEGE   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CELL ADHESION; DRUG DELIVERY; DRUG PRODUCTS; GRAFTS; HYDROGELS; LACTIC ACID; POPULATION STATISTICS; TISSUE ENGINEERING;

DRUG-LOADING EFFICIENCY; ENDOTHELIAL PROGENITOR CELLS; IMMUNOFLUORESCENCE STAINING; L-LACTIC ACID OLIGOMERS; PROMOTIONAL EFFECT; SPECIFIC GROWTH RATE; SYNTHETIC VASCULAR GRAFT; VASCULAR TISSUE ENGINEERING;

MICELLES;

GELATIN; LACTIC ACID; OLIGOMER; SILK FIBROIN; SIMVASTATIN; FIBROIN; HYDROGEL; MICELLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL GRAFT; CAROTID ARTERY; CELL ADHESION; CELL GROWTH; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; GROWTH RATE; HYDROGEL; IMMUNOFLUORESCENCE; IMPLANTATION; MALE; MICELLE; NONHUMAN; PRIORITY JOURNAL; RAT; SUSTAINED DRUG RELEASE; TISSUE ENGINEERING; ANIMAL; BLOOD VESSEL PROSTHESIS; BONE MARROW CELL; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECTS; FISCHER 344 RAT; FLUORESCENT ANTIBODY TECHNIQUE; PATHOLOGY; PHARMACOLOGY;

RATTUS;

ANIMALS; BLOOD VESSEL PROSTHESIS; BONE MARROW CELLS; CAROTID ARTERIES; CELL ADHESION; CELL MOVEMENT; CELL PROLIFERATION; ENDOTHELIAL PROGENITOR CELLS; FIBROINS; FLUORESCENT ANTIBODY TECHNIQUE; GELATIN; HYDROGEL; LACTIC ACID; MALE; MICELLES; RATS, INBRED F344; SIMVASTATIN;

EID: 84927603767     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2014.0237     Document Type: Article

References (56)

1. Thomas, L.V., Lekshmi, V., and Nair, P.D. Tissue engineered vascular grafts-preclinical aspects. Int J Cardiol 167, 1091, 2013.
2. Melchiorri, A.J., Hibino, N., and Fisher, J.P. Strategies and techniques to enhance the in situ endothelialization of small-diameter biodegradable polymeric vascular grafts. Tissue Eng Part B Rev 19, 292, 2013.
3. Menu, P., Stoltz, J.F., and Kerdjoudj, H. Progress in vascular graft substitute. Clin Hemorheol Microcirc 53, 117, 2013.
4. Llevadot, J., et al. HMG-CoA reductase inhibitor mobilizes bone marrow-derived endothelial progenitor cells. J Clin Invest 108, 399, 2001.
5. Werner, N., et al. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol 22, 1567, 2002.
6. Ii, M., and Losordo, D.W. Statins and the endothelium. Vascul Pharmacol 46, 1, 2007.
7. Spyridopoulos, I., et al. Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. Circulation 110, 3136, 2004.
8. Shao, H., et al. Statin and stromal cell-derived factor-1 additively promote angiogenesis by enhancement of progenitor cells incorporation into new vessels. Stem Cells 26, 1376, 2008.
9. Fukui, T., et al. Therapeutic effect of local administration of low-dose simvastatin-conjugated gelatin hydrogel for fracture healing. J Bone Miner Res 27, 1118, 2012.
10. Oka, S., et al. Local administration of low-dose simvastatin-conjugated gelatin hydrogel for tendon-bone healing in anterior cruciate ligament reconstruction. Tissue Eng Part A 19, 1233, 2013.
11. Tabata, Y., Yamamoto, M., and Ikada, Y. Biodegradable hydrogels for bone regeneration through growth factor release. Pure Appl Chem 70, 1277, 1998.
12. Yamamoto, M., Ikada, Y., and Tabata, Y. Controlled release of growth factors based on biodegradation of gelatin hydrogel. J Biomater Sci Polym Ed 12, 77, 2001.
13. Kimura, Y., et al. Controlled release of bone morphogenetic protein-2 enhances recruitment of osteogenic progenitor cells for de novo generation of bone tissue. Tissue Eng Part A 16, 1263, 2010.
14. Yamamoto, M., Takahashi, Y., and Tabata, Y. Controlled release by biodegradable hydrogels enhances the ectopic bone formation of bone morphogenetic protein. Biomaterials 24, 4375, 2003.
15. Ratanavaraporn, J., Furuya, H., Kohara, H., and Tabata, Y. Synergistic effects of the dual release of stromal cellderived factor-1 and bone morphogenetic protein-2 from hydrogels on bone regeneration. Biomaterials 32, 2797, 2011.
16. Hu, X., and Jing, X. Biodegradable amphiphilic polymerdrug conjugate micelles. Expert Opin Drug Deliv 6, 1079, 2009.
17. Tanigo, T., Takaoka, R., and Tabata, Y. Sustained release of water-insoluble simvastatin from biodegradable hydrogel augments bone regeneration. J Control Release 143, 201, 2010.
18. Marsh, R.E., Corey, R.B., and Pauling, L. An investigation of the structure of silkfibroin. Biochim Biophys Acta 16, 1, 1955.
19. Altman, G.H., et al. Silk-based biomaterials. Biomaterials 24, 401, 2003.
20. Komatsu, K. Chemistry and structure of silk. JARQ 13, 64, 1979.
21. Lotz, B., and Colonna Cesari, F. The chemical structure and the crystalline structures of Bombyx mori silk fibroin. Biochimie 61, 205, 1979.
22. Lu, Q., et al. Degradation mechanism and control of silk fibroin. Biomacromolecules 12, 1080, 2011.
23. Vachiraroj, N., et al. A comparison of Thai silk fibroinbased and chitosan-based materials on in vitro biocompatibility for bone substitutes. Int J Biol Macromol 45, 470, 2009.
24. Vorrapakdee, R., et al. Modification of human cancellous bone using Thai silk fibroin and gelatin for enhanced osteoconductive potential. J Mater Sci Mater Med 24, 735, 2013.
25. Sahoo, S., Toh, S.L., and Goh, J.C. A bFGF-releasing silk/ PLGA-based biohybrid scaffold for ligament/tendon tissue engineering using mesenchymal progenitor cells. Biomaterials 31, 2990, 2010.
26. Lawrence, B.D., Marchant, J.K., Pindrus, M.A., Omenetto, F.G., and Kaplan, D.L. Silk film biomaterials for cornea tissue engineering. Biomaterials 30, 1299, 2009.
27. Lovett, M., et al. Tubular silk scaffolds for small diameter vascular grafts. Organogenesis 6, 217, 2010.
28. Enomoto, S., et al. Long-term patency of small-diameter vascular graft made from fibroin, a silk-based biodegradable material. J Vasc Surg 51, 155, 2010.
29. Kanokpanont, S., Damrongsakkul, S., Ratanavaraporn, J., and Aramwit, P. An innovative bi-layered wound dressing made of silk and gelatin for accelerated wound healing. Int J Pharm 436, 141, 2012.
30. Wongputtaraksa, T., Ratanavaraporn, J., Pichyangkura, R., and Damrongsakkul, S. Surface modification of Thai silk fibroin scaffolds with gelatin and chitooligosaccharide for enhanced osteogenic differentiation of bone marrowderived mesenchymal stem cells. J Biomed Mater Res B Appl Biomater 100, 2307, 2012.
31. Kanokpanont, S., Damrongsakkul, S., Ratanavaraporn, J., and Aramwit, P. Physico-chemical properties and efficacy of silk fibroin fabric coated with different waxes as wound dressing. Int J Biol Macromol 55, 88, 2013.
32. Thitiwuthikiat, P., and Kanokpanont, S. Assessment of physical, mechanical and biological properties of Thai silk fibroin vascular scaffold. Adv Mater Res 506, 381, 2012.
33. Lovett, M., et al. Silk fibroin microtubes for blood vessel engineering. Biomaterials 28, 5271, 2007.
34. Zhang, X., et al. Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts. Biomaterials 30, 3213, 2009.
35. Marelli, B., et al. Collagen-reinforced electrospun silk fibroin tubular construct as small calibre vascular graft. Macromol Biosci 12, 1566, 2012.
36. Soffer, L., et al. Silk-based electrospun tubular scaffolds for tissue-engineered vascular grafts. J Biomater Sci Polym Ed 19, 653, 2008.
37. Bray, L.J., Suzuki, S., Harkin, D.G., and Chirila, T.V. Incorporation of exogenous RGD peptide and inter-species blending as strategies for enhancing human corneal limbal epithelial cell growth on Bombyx mori silk fibroin membranes. J Funct Biomater 4, 74, 2013.
38. Hirata, M., Kobayashi, K., and Kimura, Y. Synthesis and properties of high-molecular-weight stereo di-block polylactides with nonequivalent D/L ratios. J Polym Sci Polym Chem 48, 794, 2010.
39. Wang, Y., Chen, X., and Pelton, R. Interactions of hydrophobically modified polyvinylamine with pluronic triblock copolymer micelles. Langmuir 22, 4952, 2006.
40. Arayne, M.S., Sultana, N., Hussain, F., and Ali, S.A. Validated spectrophotometric method for quantitative determination of simvastatin in pharmaceutical formulations and human serum. J Anal Chem 62, 536, 2007.
41. Ii, M. Bone marrow-derived endothelial progenitor cells: isolation and characterization for myocardial repair. Methods Mol Biol 660, 9, 2010.
42. Kahler, C.M., et al. Peripheral infusion of rat bone marrow derived endothelial progenitor cells leads to homing in acute lung injury. Respir Res 8, 50, 2007.
43. Nakamura, T., et al. Significance and therapeutic potential of endothelial progenitor cell transplantation in a cirrhotic liver rat model. Gastroenterology 133, 91, 2007.
44. Dai, X., et al. The role of CXCR7 on the adhesion, proliferation and angiogenesis of endothelial progenitor cells. J Cell Mol Med 15, 1299, 2011.
45. Sadeghi, M.M., Collinge, M., Pardi, R., and Bender, J.R. Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein. J Immunol 165, 2712, 2000.
46. Mehrara, E., Forssell-Aronsson, E., Ahlman, H., and Bernhardt, P. Specific growth rate versus doubling time for quantitative characterization of tumor growth rate. Cancer Res 67, 3970, 2007.
47. Kim, U.J., Park, J., Kim, H.J., Wada, M., and Kaplan, D.L. Three-dimensional aqueous-derived biomaterial scaffolds from silk fibroin. Biomaterials 26, 2775, 2005.
48. Tungtasana, H., et al. Tissue response and biodegradation of composite scaffolds prepared from Thai silk fibroin, gelatin and hydroxyapatite. J Mater Sci Mater Med 21, 3151, 2010.
49. Dimmeler, S., et al. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway. J Clin Invest 108, 391, 2001.
50. Steinmetz, M., Brouwers, C., Nickenig, G., and Wassmann, S. Synergistic effects of telmisartan and simvastatin on endothelial progenitor cells. J Cell Mol Med 14, 1645, 2010.
51. Zhu, J.H., Tao, Q.M., Chen, J.Z., Wang, X.X., and Shang, Y.P. Statins contribute to enhancement of the number and the function of endothelial progenitor cells from peripheral blood. Sheng Li Xue Bao 56, 357, 2004.
52. Asakage, M., et al. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor (pravastatin) inhibits endothelial cell proliferation dependent on G1 cell cycle arrest. Anticancer Drugs 15, 625, 2004.
53. Fedel, M., et al. Blood compatibility of polymers derived from natural materials. J Bioact Compat Polym 27, 295, 2012.
54. Undas, A., Brummel, K.E., Musial, J., Mann, K.G., and Szczeklik, A. Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation. Circulation 103, 2248, 2001.
55. Walter, D.H., et al. Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells. Circulation 105, 3017, 2002.
56. Porter, K.E., et al. Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration. J Vasc Surg 36, 150, 2002.