Effects of vitamin D3 stimulation of thioredoxin-interacting protein in hepatocellular carcinoma

Hepatology Research

Volumn 44, Issue 13, 2014, Pages 1357-1366

  Hamilton, James P ^a   Potter, James J ^a   Koganti, Lahari ^a   Meltzer, Stephen J ^a,b   Mezey, Esteban ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Apoptosis; Hepatocellular carcinoma; Liver cancer; Reactive oxygen species; Thioredoxin interacting protein; Vitamin D

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COBALT CHLORIDE; COLECALCIFEROL; REACTIVE OXYGEN METABOLITE; THIOREDOXIN INTERACTING PROTEIN; VITAMIN D;

APOPTOSIS; ARTICLE; CANCER PATIENT; CANCER TISSUE; CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DOSE ESCALATION; DRUG EFFECT; EXPRESSION VECTOR; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84927575748     PISSN: 13866346     EISSN: 1872034X     Source Type: Journal    
DOI: 10.1111/hepr.12302     Document Type: Article

References (22)

1. Spindel ON, World C, Berk BC. Thioredoxin interacting protein: redox dependent and independent regulatory mechanisms. Antioxid Redox Signal 2012; 16: 587-596.
2. Zhou J, Yu Q, Chng WJ. TXNIP (VDUP-1, TBP-2): a major redox regulator commonly suppressed in cancer by epigenetic mechanisms. Int J Biochem Cell Biol 2011; 43: 1668-1673.
3. Kim SY, Suh HW, Chung JW, Yoon SR, Choi I. Diverse functions of VDUP1 in cell proliferation, differentiation, and diseases. Cell Mol Immunol 2007; 4: 345-351.
4. Kaimul AM, Nakamura H, Masutani H, Yodoi J. Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome. Free Radic Biol Med 2007; 43: 861-868.
5. Nishiyama A, Matsui M, Iwata S etal. Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression. J Biol Chem 1999; 274: 21645-21650.
6. Junn E, Han SH, Im JY etal. Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. J Immunol 2000; 164: 6287-6295.
7. Cohen JI, Roychowdhury S, DiBello PM, Jacobsen DW, Nagy LE. Exogenous thioredoxin prevents ethanol-induced oxidative damage and apoptosis in mouse liver. Hepatology 2009; 49: 1709-1717.
8. Okuyama H, Nakamura H, Shimahara Y etal. Overexpression of thioredoxin prevents acute hepatitis caused by thioacetamide or lipopolysaccharide in mice. Hepatology 2003; 37: 1015-1025.
9. Okuyama H, Nakamura H, Shimahara Y etal. Overexpression of thioredoxin prevents thioacetamide-induced hepatic fibrosis in mice. J Hepatol 2005; 42 (1): 117-123.
10. Watanabe R, Nakamura H, Masutani H, Yodoi J. Anti-oxidative, anti-cancer and anti-inflammatory actions by thioredoxin 1 and thioredoxin-binding protein-2. Pharmacol Ther 2010; 127: 261-270.
11. Han SH, Jeon JH, Ju HR etal. VDUP1 upregulated by TGF-beta1 and 1, 25-dihydorxyvitamin D3 inhibits tumor cell growth by blocking cell-cycle progression. Oncogene 2003; 22: 4035-4046.
12. Nishinaka Y, Nishiyama A, Masutani H etal. Loss of thioredoxin-binding protein-2/vitamin D3 up-regulated protein 1 in human T-cell leukemia virus type I-dependent T-cell transformation: implications for adult T-cell leukemia leukemogenesis. Cancer Res 2004; 64: 1287-1292.
13. Jeon JH, Lee KN, Hwang CY, Kwon KS, You KH, Choi I. Tumor suppressor VDUP1 increases p27(kip1) stability by inhibiting JAB1. Cancer Res 2005; 65: 4485-4489.
14. Sheth SS, Bodnar JS, Ghazalpour A etal. Hepatocellular carcinoma in Txnip-deficient mice. Oncogene 2006; 25: 3528-3536.
15. Holmgren A, Björnstedt . M. Thioreoxin and Thioredoxin reductase. Methods Enzymol 1995; 252: 199-208.
16. Potter JJ, Liu X, Koteish A, Mezey E. 1, 25-dihydroxyvitamin D3 and its nuclear receptor repress human alpha1 (I) collagen expression and type I collagen formation. Liver Int 2013; 33: 677-686.
17. Cheung FS, Lovicu FJ, Reichardt JK. Current progress in using vitamin D and its analogs for cancer prevention and treatment. Expert Rev Anticancer Ther 2012; 12: 811-837.
18. Pike JW, Meyer MB. The vitamin D receptor: new paradigms for the regulation of gene expression by 1, 25-dihydroxyvitamin D(3). Endocrinol Metab Clin North Am 2010; 39: 255-269, table of contents.
19. Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology 2008; 134: 1655-1669.
20. Marra M, Sordelli IM, Lombardi A etal. Molecular targets and oxidative stress biomarkers in hepatocellular carcinoma: an overview. J Transl Med 2011; 9: 171.
21. Crispo JA, Ansell DR, Piche M etal. Protective effects of polyphenolic compounds on oxidative stress-induced cytotoxicity in PC12 cells. Can J Physiol Pharmacol 2010; 88: 429-438.
22. Chiang KC, Yeh CN, Chen MF, Chen TC. Hepatocellular carcinoma and vitamin D: a review. J Gastroenterol Hepatol 2011; 26: 1597-1603.