메뉴 건너뛰기




Volumn 6, Issue MAR, 2015, Pages

Hantavirus-induced disruption of the endothelial barrier: Neutrophils are on the payroll

Author keywords

Hantaviruses; Immunopathogenesis; Neutrophil extracellular traps; Neutrophils; Vascular hyperpermeability; Viral hemorrhagic fever

Indexed keywords

CD18 ANTIGEN; CHEMOKINE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; VASCULOTROPIN;

EID: 84927564661     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00222     Document Type: Article
Times cited : (37)

References (116)
  • 2
    • 84877880800 scopus 로고    scopus 로고
    • A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant
    • Antonen, J., Leppanen, I., Tenhunen, J., Arvola, P., Makela, S., Vaheri, A., et al. (2013). A severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant. Scand. J. Infect. Dis. 45, 494-496. doi: 10.3109/00365548.2012.755268.
    • (2013) Scand. J. Infect. Dis , vol.45 , pp. 494-496
    • Antonen, J.1    Leppanen, I.2    Tenhunen, J.3    Arvola, P.4    Makela, S.5    Vaheri, A.6
  • 3
    • 78651492046 scopus 로고    scopus 로고
    • Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus
    • Bjorkstrom, N. K., Lindgren, T., Stoltz, M., Fauriat, C., Braun, M., Evander, M., et al. (2011). Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. J. Exp. Med. 208, 13-21. doi: 10.1084/jem.20100762.
    • (2011) J. Exp. Med , vol.208 , pp. 13-21
    • Bjorkstrom, N.K.1    Lindgren, T.2    Stoltz, M.3    Fauriat, C.4    Braun, M.5    Evander, M.6
  • 4
    • 0030740177 scopus 로고    scopus 로고
    • Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines
    • Blum, M. S., Toninelli, E., Anderson, J. M., Balda, M. S., Zhou, J., O'Donnell, L., et al. (1997). Cytoskeletal rearrangement mediates human microvascular endothelial tight junction modulation by cytokines. Am. J. Physiol. 273, H286-H294.
    • (1997) Am. J. Physiol , vol.273 , pp. H286-H294
    • Blum, M.S.1    Toninelli, E.2    Anderson, J.M.3    Balda, M.S.4    Zhou, J.5    O'Donnell, L.6
  • 5
    • 54149084525 scopus 로고    scopus 로고
    • Role of mixed Th1 and Th2 serum cytokines on pathogenesis and prognosis of hantavirus pulmonary syndrome
    • Borges, A. A., Campos, G. M., Moreli, M. L., Moro Souza, R. L., Saggioro, F. P., Figueiredo, G. G., et al. (2008). Role of mixed Th1 and Th2 serum cytokines on pathogenesis and prognosis of hantavirus pulmonary syndrome. Microbes Infect. 10, 1150-1157. doi: 10.1016/j.micinf.2008.06.006.
    • (2008) Microbes Infect , vol.10 , pp. 1150-1157
    • Borges, A.A.1    Campos, G.M.2    Moreli, M.L.3    Moro Souza, R.L.4    Saggioro, F.P.5    Figueiredo, G.G.6
  • 6
    • 77953325982 scopus 로고    scopus 로고
    • Association of-308G/A polymorphism in the tumor necrosis factor-α gene promoter with susceptibility to development of hantavirus cardiopulmonary syndrome in the Ribeirao Preto region, Brazil
    • Borges, A. A., Donadi, E. A., Campos, G. M., Moreli, M. L., de Sousa, R. L., Saggioro, F. P., et al. (2010). Association of-308G/A polymorphism in the tumor necrosis factor-α gene promoter with susceptibility to development of hantavirus cardiopulmonary syndrome in the Ribeirao Preto region, Brazil. Arch. Virol. 155, 971-975. doi: 10.1007/s00705-010-0655-7.
    • (2010) Arch. Virol , vol.155 , pp. 971-975
    • Borges, A.A.1    Donadi, E.A.2    Campos, G.M.3    Moreli, M.L.4    de Sousa, R.L.5    Saggioro, F.P.6
  • 7
    • 80051799733 scopus 로고    scopus 로고
    • Cross-talk between the complement and the kinin system in vascular permeability
    • Bossi, F., Peerschke, E. I., Ghebrehiwet, B., and Tedesco, F. (2011). Cross-talk between the complement and the kinin system in vascular permeability. Immunol. Lett. 140, 7-13. doi: 10.1016/j.imlet.2011.06.006.
    • (2011) Immunol. Lett , vol.140 , pp. 7-13
    • Bossi, F.1    Peerschke, E.I.2    Ghebrehiwet, B.3    Tedesco, F.4
  • 8
    • 84912122993 scopus 로고    scopus 로고
    • NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Ra expression
    • Braun, M., Bjorkstrom, N. K., Gupta, S., Sundstrom, K., Ahlm, C., Klingstrom, J., et al. (2014). NK cell activation in human hantavirus infection explained by virus-induced IL-15/IL15Ra expression. PLoS Pathog. 10:e1004521. doi: 10.1371/journal.ppat.1004521.
    • (2014) PLoS Pathog , vol.10
    • Braun, M.1    Bjorkstrom, N.K.2    Gupta, S.3    Sundstrom, K.4    Ahlm, C.5    Klingstrom, J.6
  • 10
    • 84863548610 scopus 로고    scopus 로고
    • Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury
    • Caudrillier, A., Kessenbrock, K., Gilliss, B. M., Nguyen, J. X., Marques, M. B., Monestier, M., et al. (2012). Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury. J. Clin. Invest. 122, 2661-2671. doi: 10.1172/JCI61303.
    • (2012) J. Clin. Invest , vol.122 , pp. 2661-2671
    • Caudrillier, A.1    Kessenbrock, K.2    Gilliss, B.M.3    Nguyen, J.X.4    Marques, M.B.5    Monestier, M.6
  • 11
    • 84901476015 scopus 로고    scopus 로고
    • Immunogenetic factors affecting susceptibility of humans and rodents to hantaviruses and the clinical course of hantaviral disease in humans
    • Charbonnel, N., Pages, M., Sironen, T., Henttonen, H., Vapalahti, O., Mustonen, J., et al. (2014). Immunogenetic factors affecting susceptibility of humans and rodents to hantaviruses and the clinical course of hantaviral disease in humans. Viruses 6, 2214-2241. doi: 10.3390/v6052214.
    • (2014) Viruses , vol.6 , pp. 2214-2241
    • Charbonnel, N.1    Pages, M.2    Sironen, T.3    Henttonen, H.4    Vapalahti, O.5    Mustonen, J.6
  • 12
    • 34147188469 scopus 로고    scopus 로고
    • Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
    • Clark, S. R., Ma, A. C., Tavener, S. A., McDonald, B., Goodarzi, Z., Kelly, M. M., et al. (2007). Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat. Med. 13, 463-469. doi: 10.1038/nm1565.
    • (2007) Nat. Med , vol.13 , pp. 463-469
    • Clark, S.R.1    Ma, A.C.2    Tavener, S.A.3    McDonald, B.4    Goodarzi, Z.5    Kelly, M.M.6
  • 13
    • 0028094856 scopus 로고
    • Hantavirus pulmonary syndrome in New England and Europe
    • Clement, J., Colson, P., and McKenna, P. (1994). Hantavirus pulmonary syndrome in New England and Europe. N. Engl. J. Med. 331, 545-546. doi: 10.1056/NEJM199408253310813.
    • (1994) N. Engl. J. Med , vol.331 , pp. 545-546
    • Clement, J.1    Colson, P.2    McKenna, P.3
  • 14
    • 84902295775 scopus 로고    scopus 로고
    • Hemorrhagic fever with renal syndrome in the new, and Hantavirus Pulmonary Syndrome in the old world: paradi(se)gm lost or regained?
    • Clement, J., Maes, P., and Van, R. M. (2014). Hemorrhagic fever with renal syndrome in the new, and Hantavirus Pulmonary Syndrome in the old world: paradi(se)gm lost or regained? Virus Res. 187, 55-58. doi: 10.1016/j.virusres.2013.12.036.
    • (2014) Virus Res , vol.187 , pp. 55-58
    • Clement, J.1    Maes, P.2    Van, R.M.3
  • 15
    • 0028215049 scopus 로고
    • Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. The Hantavirus Study Group
    • Duchin, J. S., Koster, F. T., Peters, C. J., Simpson, G. L., Tempest, B., Zaki, S. R., et al. (1994). Hantavirus pulmonary syndrome: a clinical description of 17 patients with a newly recognized disease. The Hantavirus Study Group. N. Engl. J. Med. 330, 949-955. doi: 10.1056/NEJM199404073301401.
    • (1994) N. Engl. J. Med , vol.330 , pp. 949-955
    • Duchin, J.S.1    Koster, F.T.2    Peters, C.J.3    Simpson, G.L.4    Tempest, B.5    Zaki, S.R.6
  • 16
  • 17
    • 84903754587 scopus 로고    scopus 로고
    • Neutrophils recruited by chemoattractants in vivo induce microvascular plasma protein leakage through secretion of TNF
    • Finsterbusch, M., Voisin, M. B., Beyrau, M., Williams, T. J., and Nourshargh, S. (2014). Neutrophils recruited by chemoattractants in vivo induce microvascular plasma protein leakage through secretion of TNF. J. Exp. Med. 211, 1307-1314. doi: 10.1084/jem.20132413.
    • (2014) J. Exp. Med , vol.211 , pp. 1307-1314
    • Finsterbusch, M.1    Voisin, M.B.2    Beyrau, M.3    Williams, T.J.4    Nourshargh, S.5
  • 18
    • 80053354116 scopus 로고    scopus 로고
    • Histones induce rapid and profound thrombocytopenia in mice
    • Fuchs, T. A., Bhandari, A. A., and Wagner, D. D. (2011). Histones induce rapid and profound thrombocytopenia in mice. Blood 118, 3708-3714. doi: 10.1182/blood-2011-01-332676.
    • (2011) Blood , vol.118 , pp. 3708-3714
    • Fuchs, T.A.1    Bhandari, A.A.2    Wagner, D.D.3
  • 19
    • 84873808147 scopus 로고    scopus 로고
    • Elevated VEGF levels in pulmonary edema fluid and PBMCs from patients with acute Hantavirus Pulmonary Syndrome
    • 674360
    • Gavrilovskaya, I., Gorbunova, E., Koster, F., and Mackow, E. (2012). Elevated VEGF levels in pulmonary edema fluid and PBMCs from patients with acute Hantavirus Pulmonary Syndrome. Adv. Virol. 2012, 674360. doi: 10.1155/2012/674360.
    • (2012) Adv. Virol , vol.2012
    • Gavrilovskaya, I.1    Gorbunova, E.2    Koster, F.3    Mackow, E.4
  • 20
    • 44949117721 scopus 로고    scopus 로고
    • Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor, VEGF, while angiopoietin-1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability
    • Gavrilovskaya, I. N., Gorbunova, E. E., Mackow, N. A., and Mackow, E. R. (2008). Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor, VEGF, while angiopoietin-1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability. J. Virol. 82, 5797-5806. doi: 10.1128/JVI.02397-07.
    • (2008) J. Virol , vol.82 , pp. 5797-5806
    • Gavrilovskaya, I.N.1    Gorbunova, E.E.2    Mackow, N.A.3    Mackow, E.R.4
  • 21
    • 0037109041 scopus 로고    scopus 로고
    • Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responses
    • Geimonen, E., Neff, S., Raymond, T., Kocer, S. S., Gavrilovskaya, I. N., and Mackow, E. R. (2002). Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responses. Proc. Natl. Acad. Sci. U.S.A. 99, 13837-13842. doi: 10.1073/pnas.192298899.
    • (2002) Proc. Natl. Acad. Sci. U.S.A , vol.99 , pp. 13837-13842
    • Geimonen, E.1    Neff, S.2    Raymond, T.3    Kocer, S.S.4    Gavrilovskaya, I.N.5    Mackow, E.R.6
  • 22
    • 84890558721 scopus 로고    scopus 로고
    • Another case of 'European hantavirus pulmonary syndrome' with severe lung, prior to kidney, involvement, and diagnosed by viral inclusions in lung macrophages
    • Gizzi, M., Delaere, B., Weynand, B., Clement, J., Maes, P., Vergote, V., et al. (2013). Another case of "European hantavirus pulmonary syndrome" with severe lung, prior to kidney, involvement, and diagnosed by viral inclusions in lung macrophages. Eur. J. Clin. Microbiol. Infect. Dis. 32, 1341-1345. doi: 10.1007/s10096-013-1885-x.
    • (2013) Eur. J. Clin. Microbiol. Infect. Dis , vol.32 , pp. 1341-1345
    • Gizzi, M.1    Delaere, B.2    Weynand, B.3    Clement, J.4    Maes, P.5    Vergote, V.6
  • 23
    • 77953763318 scopus 로고    scopus 로고
    • Pathogenic hantaviruses Andes virus and Hantaan virus induce adherens junction disassembly by directing vascular endothelial cadherin internalization in human endothelial cells
    • Gorbunova, E., Gavrilovskaya, I. N., and Mackow, E. R. (2010). Pathogenic hantaviruses Andes virus and Hantaan virus induce adherens junction disassembly by directing vascular endothelial cadherin internalization in human endothelial cells. J. Virol. 84, 7405-7411. doi: 10.1128/JVI.00576-10.
    • (2010) J. Virol , vol.84 , pp. 7405-7411
    • Gorbunova, E.1    Gavrilovskaya, I.N.2    Mackow, E.R.3
  • 24
    • 0035062597 scopus 로고    scopus 로고
    • Noncytolytic control of viral infections by the innate and adaptive immune response
    • Guidotti, L. G., and Chisari, F. V. (2001). Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 19, 65-91. doi: 10.1146/annurev.immunol.19.1.65.
    • (2001) Annu. Rev. Immunol , vol.19 , pp. 65-91
    • Guidotti, L.G.1    Chisari, F.V.2
  • 25
    • 77954176096 scopus 로고    scopus 로고
    • Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death
    • Gupta, A. K., Joshi, M. B., Philippova, M., Erne, P., Hasler, P., Hahn, S., et al. (2010). Activated endothelial cells induce neutrophil extracellular traps and are susceptible to NETosis-mediated cell death. FEBS Lett. 584, 3193-3197. doi: 10.1016/j.febslet.2010.06.006.
    • (2010) FEBS Lett , vol.584 , pp. 3193-3197
    • Gupta, A.K.1    Joshi, M.B.2    Philippova, M.3    Erne, P.4    Hasler, P.5    Hahn, S.6
  • 26
    • 84875978198 scopus 로고    scopus 로고
    • Hantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis
    • Gupta, S., Braun, M., Tischler, N. D., Stoltz, M., Sundstrom, K. B., Bjorkstrom, N. K., et al. (2013). Hantavirus-infection confers resistance to cytotoxic lymphocyte-mediated apoptosis. PLoS. Pathog. 9:e1003272. doi: 10.1371/journal.ppat.1003272.
    • (2013) PLoS. Pathog , vol.9
    • Gupta, S.1    Braun, M.2    Tischler, N.D.3    Stoltz, M.4    Sundstrom, K.B.5    Bjorkstrom, N.K.6
  • 27
    • 33846027112 scopus 로고    scopus 로고
    • Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes
    • Hayasaka, D., Maeda, K., Ennis, F. A., and Terajima, M. (2007). Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes. Virus Res. 123, 120-127. doi: 10.1016/j.virusres.2006.08.006.
    • (2007) Virus Res , vol.123 , pp. 120-127
    • Hayasaka, D.1    Maeda, K.2    Ennis, F.A.3    Terajima, M.4
  • 29
    • 84914128755 scopus 로고    scopus 로고
    • DNA vaccine-derived human IgG produced in transchromosomal bovines protect in lethal models of hantavirus pulmonary syndrome
    • Hooper, J. W., Brocato, R. L., Kwilas, S. A., Hammerbeck, C. D., Josleyn, M. D., Royals, M., et al. (2014). DNA vaccine-derived human IgG produced in transchromosomal bovines protect in lethal models of hantavirus pulmonary syndrome. Sci. Transl. Med. 6, 264ra162. doi: 10.1126/scitranslmed.3010082.
    • (2014) Sci. Transl. Med , vol.6
    • Hooper, J.W.1    Brocato, R.L.2    Kwilas, S.A.3    Hammerbeck, C.D.4    Josleyn, M.D.5    Royals, M.6
  • 30
    • 33750335098 scopus 로고    scopus 로고
    • Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus
    • Jahnsen, F. L., Strickland, D. H., Thomas, J. A., Tobagus, I. T., Napoli, S., Zosky, G. R., et al. (2006). Accelerated antigen sampling and transport by airway mucosal dendritic cells following inhalation of a bacterial stimulus. J. Immunol. 177, 5861-5867. doi: 10.4049/jimmunol.177.9.5861.
    • (2006) J. Immunol , vol.177 , pp. 5861-5867
    • Jahnsen, F.L.1    Strickland, D.H.2    Thomas, J.A.3    Tobagus, I.T.4    Napoli, S.5    Zosky, G.R.6
  • 31
    • 34247357725 scopus 로고    scopus 로고
    • The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps
    • Jaillon, S., Peri, G., Delneste, Y., Fremaux, I., Doni, A., Moalli, F., et al. (2007). The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. J. Exp. Med. 204, 793-804. doi: 10.1084/jem.20061301.
    • (2007) J. Exp. Med , vol.204 , pp. 793-804
    • Jaillon, S.1    Peri, G.2    Delneste, Y.3    Fremaux, I.4    Doni, A.5    Moalli, F.6
  • 32
    • 84873918079 scopus 로고    scopus 로고
    • Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps
    • Jenne, C. N., Wong, C. H., Zemp, F. J., McDonald, B., Rahman, M. M., Forsyth, P. A., et al. (2013). Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps. Cell Host Microbe 13, 169-180. doi: 10.1016/j.chom.2013.01.005.
    • (2013) Cell Host Microbe , vol.13 , pp. 169-180
    • Jenne, C.N.1    Wong, C.H.2    Zemp, F.J.3    McDonald, B.4    Rahman, M.M.5    Forsyth, P.A.6
  • 33
    • 77950651664 scopus 로고    scopus 로고
    • A global perspective on hantavirus ecology, epidemiology, and disease
    • Jonsson, C. B., Figueiredo, L. T., and Vapalahti, O. (2010). A global perspective on hantavirus ecology, epidemiology, and disease. Clin. Microbiol. Rev. 23, 412-441. doi: 10.1128/CMR.00062-09.
    • (2010) Clin. Microbiol. Rev , vol.23 , pp. 412-441
    • Jonsson, C.B.1    Figueiredo, L.T.2    Vapalahti, O.3
  • 34
    • 0032423206 scopus 로고    scopus 로고
    • High-producer allele of tumour necrosis factor-alpha is part of the susceptibility MHC haplotype in severe Puumala virus-induced nephropathia epidemica
    • Kanerva, M., Vaheri, A., Mustonen, J., and Partanen, J. (1998). High-producer allele of tumour necrosis factor-alpha is part of the susceptibility MHC haplotype in severe Puumala virus-induced nephropathia epidemica. Scand. J. Infect. Dis. 30, 532-534. doi: 10.1080/00365549850161629.
    • (1998) Scand. J. Infect. Dis , vol.30 , pp. 532-534
    • Kanerva, M.1    Vaheri, A.2    Mustonen, J.3    Partanen, J.4
  • 35
    • 0034469162 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor alpha on sin nombre virus infection in vitro
    • Khaiboullina, S. F., Netski, D. M., Krumpe, P., and St Jeor, S. C. (2000). Effects of tumor necrosis factor alpha on sin nombre virus infection in vitro. J. Virol. 74, 11966-11971. doi: 10.1128/JVI.74.24.11966-11971.2000.
    • (2000) J. Virol , vol.74 , pp. 11966-11971
    • Khaiboullina, S.F.1    Netski, D.M.2    Krumpe, P.3    St Jeor, S.C.4
  • 37
    • 0141889121 scopus 로고    scopus 로고
    • Occurrence of renal and pulmonary syndrome in a region of northeast Germany where Tula hantavirus circulates
    • Klempa, B., Meisel, H., Rath, S., Bartel, J., Ulrich, R., and Kruger, D. H. (2003). Occurrence of renal and pulmonary syndrome in a region of northeast Germany where Tula hantavirus circulates. J. Clin. Microbiol. 41, 4894-4897. doi: 10.1128/JCM.41.10.4894-4897.2003.
    • (2003) J. Clin. Microbiol , vol.41 , pp. 4894-4897
    • Klempa, B.1    Meisel, H.2    Rath, S.3    Bartel, J.4    Ulrich, R.5    Kruger, D.H.6
  • 38
    • 33746812588 scopus 로고    scopus 로고
    • Loss of cell membrane integrity in Puumala hantavirus-infected patients correlates with levels of epithelial cell apoptosis and perforin
    • Klingstrom, J., Hardestam, J., Stoltz, M., Zuber, B., Lundkvist, A., Linder, S., et al. (2006). Loss of cell membrane integrity in Puumala hantavirus-infected patients correlates with levels of epithelial cell apoptosis and perforin. J. Virol. 80, 8279-8282. doi: 10.1128/JVI.00742-06.
    • (2006) J. Virol , vol.80 , pp. 8279-8282
    • Klingstrom, J.1    Hardestam, J.2    Stoltz, M.3    Zuber, B.4    Lundkvist, A.5    Linder, S.6
  • 39
    • 46249105042 scopus 로고    scopus 로고
    • Sex-dependent differences in plasma cytokine responses to hantavirus infection
    • Klingstrom, J., Lindgren, T., and Ahlm, C. (2008). Sex-dependent differences in plasma cytokine responses to hantavirus infection. Clin. Vaccine Immunol. 15, 885-887. doi: 10.1128/CVI.00035-08.
    • (2008) Clin. Vaccine Immunol , vol.15 , pp. 885-887
    • Klingstrom, J.1    Lindgren, T.2    Ahlm, C.3
  • 40
    • 84901992357 scopus 로고    scopus 로고
    • Neutrophil depletion suppresses pulmonary vascular hyperpermeability and occurrence of pulmonary edema caused by hantavirus infection in C.B-17 SCID mice
    • Koma, T., Yoshimatsu, K., Nagata, N., Sato, Y., Shimizu, K., Yasuda, S. P., et al. (2014). Neutrophil depletion suppresses pulmonary vascular hyperpermeability and occurrence of pulmonary edema caused by hantavirus infection in C.B-17 SCID mice. J. Virol. 88, 7178-7188. doi: 10.1128/JVI.00254-14.
    • (2014) J. Virol , vol.88 , pp. 7178-7188
    • Koma, T.1    Yoshimatsu, K.2    Nagata, N.3    Sato, Y.4    Shimizu, K.5    Yasuda, S.P.6
  • 41
    • 2642567552 scopus 로고    scopus 로고
    • Differential antiviral response of endothelial cells after infection with pathogenic and nonpathogenic hantaviruses
    • Kraus, A. A., Raftery, M. J., Giese, T., Ulrich, R., Zawatzky, R., Hippenstiel, S., et al. (2004). Differential antiviral response of endothelial cells after infection with pathogenic and nonpathogenic hantaviruses. J. Virol. 78, 6143-6150. doi: 10.1128/JVI.78.12.6143-6150.2004.
    • (2004) J. Virol , vol.78 , pp. 6143-6150
    • Kraus, A.A.1    Raftery, M.J.2    Giese, T.3    Ulrich, R.4    Zawatzky, R.5    Hippenstiel, S.6
  • 42
    • 84890862250 scopus 로고    scopus 로고
    • Mobilization of circulating endothelial progenitor cells correlates with the clinical course of hantavirus disease
    • Krautkrämer, E., Grouls, S., Hettwer, D., Rafat, N., Tonshoff, B., and Zeier, M. (2014). Mobilization of circulating endothelial progenitor cells correlates with the clinical course of hantavirus disease. J. Virol. 88, 483-489. doi: 10.1128/JVI.02063-13.
    • (2014) J. Virol , vol.88 , pp. 483-489
    • Krautkrämer, E.1    Grouls, S.2    Hettwer, D.3    Rafat, N.4    Tonshoff, B.5    Zeier, M.6
  • 43
    • 80054006066 scopus 로고    scopus 로고
    • Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts
    • Krautkrämer, E., Grouls, S., Stein, N., Reiser, J., and Zeier, M. (2011). Pathogenic old world hantaviruses infect renal glomerular and tubular cells and induce disassembling of cell-to-cell contacts. J. Virol. 85, 9811-9823. doi: 10.1128/JVI.00568-11.
    • (2011) J. Virol , vol.85 , pp. 9811-9823
    • Krautkrämer, E.1    Grouls, S.2    Stein, N.3    Reiser, J.4    Zeier, M.5
  • 44
    • 84871805932 scopus 로고    scopus 로고
    • Hantavirus infection: an emerging infectious disease causing acute renal failure
    • Krautkrämer, E., Zeier, M., and Plyusnin, A. (2013). Hantavirus infection: an emerging infectious disease causing acute renal failure. Kidney Int. 83, 23-27. doi: 10.1038/ki.2012.360.
    • (2013) Kidney Int , vol.83 , pp. 23-27
    • Krautkrämer, E.1    Zeier, M.2    Plyusnin, A.3
  • 45
    • 84923323250 scopus 로고    scopus 로고
    • Hantaviruses-Globally emerging pathogens
    • Krüger, D. H., Figueiredo, L. T., Song, J. W., and Klempa, B. (2015). Hantaviruses-Globally emerging pathogens. J. Clin. Virol. 64, 128-136. doi: 10.1016/j.jcv.2014.08.033.
    • (2015) J. Clin. Virol , vol.64 , pp. 128-136
    • Krüger, D.H.1    Figueiredo, L.T.2    Song, J.W.3    Klempa, B.4
  • 46
    • 79959371873 scopus 로고    scopus 로고
    • Human pathogenic hantaviruses and prevention of infection
    • Krüger, D. H., Schönrich, G., and Klempa, B. (2011). Human pathogenic hantaviruses and prevention of infection. Hum. Vaccin. 7, 685-693. doi: 10.4161/hv.7.6.15197.
    • (2011) Hum. Vaccin , vol.7 , pp. 685-693
    • Krüger, D.H.1    Schönrich, G.2    Klempa, B.3
  • 47
    • 84906895913 scopus 로고    scopus 로고
    • A hantavirus pulmonary syndrome (HPS) DNA vaccine delivered using a spring-powered jet injector elicits a potent neutralizing antibody response in rabbits and nonhuman primates
    • Kwilas, S., Kishimori, J. M., Josleyn, M., Jerke, K., Ballantyne, J., Royals, M., et al. (2014). A hantavirus pulmonary syndrome (HPS) DNA vaccine delivered using a spring-powered jet injector elicits a potent neutralizing antibody response in rabbits and nonhuman primates. Curr. Gene Ther. 14, 200-210. doi: 10.2174/1566523214666140522122633.
    • (2014) Curr. Gene Ther , vol.14 , pp. 200-210
    • Kwilas, S.1    Kishimori, J.M.2    Josleyn, M.3    Jerke, K.4    Ballantyne, J.5    Royals, M.6
  • 48
    • 84878478421 scopus 로고    scopus 로고
    • Serum TNF-a, sTNFR1, IL-6, IL-8 and IL-10 levels in hemorrhagic fever with renal syndrome
    • Kyriakidis, I., and Papa, A. (2013). Serum TNF-a, sTNFR1, IL-6, IL-8 and IL-10 levels in hemorrhagic fever with renal syndrome. Virus Res. 175, 91-94. doi: 10.1016/j.virusres.2013.03.020.
    • (2013) Virus Res , vol.175 , pp. 91-94
    • Kyriakidis, I.1    Papa, A.2
  • 49
    • 77955709033 scopus 로고    scopus 로고
    • Enhanced thrombin formation and fibrinolysis during acute Puumala hantavirus infection
    • Laine, O., Makela, S., Mustonen, J., Huhtala, H., Szanto, T., Vaheri, A., et al. (2010). Enhanced thrombin formation and fibrinolysis during acute Puumala hantavirus infection. Thromb. Res. 126, 154-158. doi: 10.1016/j.thromres.2010.05.025.
    • (2010) Thromb. Res , vol.126 , pp. 154-158
    • Laine, O.1    Makela, S.2    Mustonen, J.3    Huhtala, H.4    Szanto, T.5    Vaheri, A.6
  • 50
    • 84885796366 scopus 로고    scopus 로고
    • Hantaviral mechanisms driving HLA class I antigen presentation require both RIG-I and TRIF
    • Lalwani, P., Raftery, M. J., Kobak, L., Rang, A., Giese, T., Matthaei, M., et al. (2013). Hantaviral mechanisms driving HLA class I antigen presentation require both RIG-I and TRIF. Eur. J. Immunol. 43, 2566-2576. doi: 10.1002/eji.201243066.
    • (2013) Eur. J. Immunol , vol.43 , pp. 2566-2576
    • Lalwani, P.1    Raftery, M.J.2    Kobak, L.3    Rang, A.4    Giese, T.5    Matthaei, M.6
  • 51
    • 84894488327 scopus 로고    scopus 로고
    • Neutrophil integrin affinity regulation in adhesion, migration, and bacterial clearance
    • Langereis, J. D. (2013). Neutrophil integrin affinity regulation in adhesion, migration, and bacterial clearance. Cell Adh. Migr. 7, 476-481. doi: 10.4161/cam.27293.
    • (2013) Cell Adh. Migr , vol.7 , pp. 476-481
    • Langereis, J.D.1
  • 53
    • 84880602212 scopus 로고    scopus 로고
    • Elevated vascular endothelial growth factor levels induce hyperpermeability of endothelial cells in hantavirus infection
    • Li, Y., Wang, W., Wang, J. P., Pan, L., Zhang, Y., Yu, H. T., et al. (2012). Elevated vascular endothelial growth factor levels induce hyperpermeability of endothelial cells in hantavirus infection. J. Int. Med. Res. 40, 1812-1821. doi: 10.1177/030006051204000519.
    • (2012) J. Int. Med. Res , vol.40 , pp. 1812-1821
    • Li, Y.1    Wang, W.2    Wang, J.P.3    Pan, L.4    Zhang, Y.5    Yu, H.T.6
  • 54
    • 84859865350 scopus 로고    scopus 로고
    • The degree of leukocytosis and urine GATA-3 mRNA levels are risk factors for severe acute kidney injury in Puumala virus nephropathia epidemica
    • Libraty, D. H., Makela, S., Vlk, J., Hurme, M., Vaheri, A., Ennis, F. A., et al. (2012). The degree of leukocytosis and urine GATA-3 mRNA levels are risk factors for severe acute kidney injury in Puumala virus nephropathia epidemica. PLoS ONE 7:e35402. doi: 10.1371/journal.pone.0035402.
    • (2012) PLoS ONE , vol.7
    • Libraty, D.H.1    Makela, S.2    Vlk, J.3    Hurme, M.4    Vaheri, A.5    Ennis, F.A.6
  • 55
    • 0030051430 scopus 로고    scopus 로고
    • Elevated plasma levels of tumor necrosis factor (TNF)-a, soluble TNF receptors, interleukin (IL)-6, and IL-10 in patients with hemorrhagic fever with renal syndrome
    • Linderholm, M., Ahlm, C., Settergren, B., Waage, A., and Tarnvik, A. (1996). Elevated plasma levels of tumor necrosis factor (TNF)-a, soluble TNF receptors, interleukin (IL)-6, and IL-10 in patients with hemorrhagic fever with renal syndrome. J. Infect. Dis. 173, 38-43. doi: 10.1093/infdis/173.1.38.
    • (1996) J. Infect. Dis , vol.173 , pp. 38-43
    • Linderholm, M.1    Ahlm, C.2    Settergren, B.3    Waage, A.4    Tarnvik, A.5
  • 56
    • 0001385341 scopus 로고
    • The pathology of thirty-nine fatal cases of epidemic hemorrhagic fever
    • Lukes, R. J. (1954). The pathology of thirty-nine fatal cases of epidemic hemorrhagic fever. Am. J. Med. 16, 639-650. doi: 10.1016/0002-9343(54)90270-3.
    • (1954) Am. J. Med , vol.16 , pp. 639-650
    • Lukes, R.J.1
  • 57
    • 84868709377 scopus 로고    scopus 로고
    • Sustained high level of serum VEGF at convalescent stage contributes to the renal recovery after HTNV infection in patients with hemorrhagic fever with renal syndrome
    • 812386
    • Ma, Y., Liu, B., Yuan, B., Wang, J., Yu, H., Zhang, Y., et al. (2012). Sustained high level of serum VEGF at convalescent stage contributes to the renal recovery after HTNV infection in patients with hemorrhagic fever with renal syndrome. Clin. Dev. Immunol. 2012, 812386. doi: 10.1155/2012/812386.
    • (2012) Clin. Dev. Immunol , vol.2012
    • Ma, Y.1    Liu, B.2    Yuan, B.3    Wang, J.4    Yu, H.5    Zhang, Y.6
  • 58
    • 79959914864 scopus 로고    scopus 로고
    • Hantavirus pulmonary syndrome, United States, 1993-2009
    • MacNeil, A., Ksiazek, T. G., and Rollin, P. E. (2011). Hantavirus pulmonary syndrome, United States, 1993-2009. Emerg. Infect. Dis. 17, 1195-1201. doi: 10.3201/eid1707.101306.
    • (2011) Emerg. Infect. Dis , vol.17 , pp. 1195-1201
    • MacNeil, A.1    Ksiazek, T.G.2    Rollin, P.E.3
  • 59
    • 33750949421 scopus 로고    scopus 로고
    • Tumor necrosis factor-α genetic predisposing factors can influence clinical severity in nephropathia epidemica
    • Maes, P., Clement, J., Groeneveld, P. H., Colson, P., Huizinga, T. W., and Van Ranst, M. (2006). Tumor necrosis factor-α genetic predisposing factors can influence clinical severity in nephropathia epidemica. Viral Immunol. 19, 558-564. doi: 10.1089/vim.2006.19.558.
    • (2006) Viral Immunol , vol.19 , pp. 558-564
    • Maes, P.1    Clement, J.2    Groeneveld, P.H.3    Colson, P.4    Huizinga, T.W.5    Van Ranst, M.6
  • 60
    • 0037105689 scopus 로고    scopus 로고
    • Human leukocyte antigen-B8-DR3 is a more important risk factor for severe Puumala hantavirus infection than the tumor necrosis factor-a(-308) G/A polymorphism
    • Makela, S., Mustonen, J., Ala-Houhala, I., Hurme, M., Partanen, J., Vapalahti, O., et al. (2002). Human leukocyte antigen-B8-DR3 is a more important risk factor for severe Puumala hantavirus infection than the tumor necrosis factor-a(-308) G/A polymorphism. J. Infect. Dis. 186, 843-846. doi: 10.1086/342413.
    • (2002) J. Infect. Dis , vol.186 , pp. 843-846
    • Makela, S.1    Mustonen, J.2    Ala-Houhala, I.3    Hurme, M.4    Partanen, J.5    Vapalahti, O.6
  • 61
    • 38049129557 scopus 로고    scopus 로고
    • Pathogenic hantaviruses elicit different immunoreactions in THP-1 cells and primary monocytes and induce differentiation of human monocytes to dendritic-like cells
    • Markotic, A., Hensley, L., Daddario, K., Spik, K., Anderson, K., and Schmaljohn, C. (2007). Pathogenic hantaviruses elicit different immunoreactions in THP-1 cells and primary monocytes and induce differentiation of human monocytes to dendritic-like cells. Coll. Antropol. 31, 1159-1167.
    • (2007) Coll. Antropol , vol.31 , pp. 1159-1167
    • Markotic, A.1    Hensley, L.2    Daddario, K.3    Spik, K.4    Anderson, K.5    Schmaljohn, C.6
  • 62
    • 79955798057 scopus 로고    scopus 로고
    • Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability
    • Marsac, D., Garcia, S., Fournet, A., Aguirre, A., Pino, K., Ferres, M., et al. (2011). Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability. Virol. J. 8, 223. doi: 10.1186/1743-422X-8-223.
    • (2011) Virol. J , vol.8 , pp. 223
    • Marsac, D.1    Garcia, S.2    Fournet, A.3    Aguirre, A.4    Pino, K.5    Ferres, M.6
  • 63
    • 84907294588 scopus 로고    scopus 로고
    • Person-to-person household and nosocomial transmission of andes hantavirus, Southern Chile, 2011
    • Martinez-Valdebenito, C., Calvo, M., Vial, C., Mansilla, R., Marco, C., Palma, R. E., et al. (2014). Person-to-person household and nosocomial transmission of andes hantavirus, Southern Chile, 2011. Emerg. Infect. Dis. 20, 1629-1636. doi: 10.3201/eid2010.140353.
    • (2014) Emerg. Infect. Dis , vol.20 , pp. 1629-1636
    • Martinez-Valdebenito, C.1    Calvo, M.2    Vial, C.3    Mansilla, R.4    Marco, C.5    Palma, R.E.6
  • 64
    • 77955410626 scopus 로고    scopus 로고
    • Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
    • Massberg, S., Grahl, L., von Bruehl, M. L., Manukyan, D., Pfeiler, S., Goosmann, C., et al. (2010). Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat. Med. 16, 887-896. doi: 10.1038/nm.2184.
    • (2010) Nat. Med , vol.16 , pp. 887-896
    • Massberg, S.1    Grahl, L.2    von Bruehl, M.L.3    Manukyan, D.4    Pfeiler, S.5    Goosmann, C.6
  • 65
    • 84866386143 scopus 로고    scopus 로고
    • Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis
    • McDonald, B., Urrutia, R., Yipp, B. G., Jenne, C. N., and Kubes, P. (2012). Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis. Cell Host Microbe 12, 324-333. doi: 10.1016/j.chom.2012.06.011.
    • (2012) Cell Host Microbe , vol.12 , pp. 324-333
    • McDonald, B.1    Urrutia, R.2    Yipp, B.G.3    Jenne, C.N.4    Kubes, P.5
  • 66
    • 0000018619 scopus 로고
    • Sur la lutte des cellules de l'organisme contre l'invasion de microbes
    • Metchnikoff, E. (1887). Sur la lutte des cellules de l'organisme contre l'invasion de microbes. Ann. Inst. Pasteur. 1, 321-326.
    • (1887) Ann. Inst. Pasteur , vol.1 , pp. 321-326
    • Metchnikoff, E.1
  • 67
    • 0037871469 scopus 로고    scopus 로고
    • Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells
    • Monsinjon, T., Gasque, P., Chan, P., Ischenko, A., Brady, J. J., and Fontaine, M. C. (2003). Regulation by complement C3a and C5a anaphylatoxins of cytokine production in human umbilical vein endothelial cells. FASEB J. 17, 1003-1014. doi: 10.1096/fj.02-0737com.
    • (2003) FASEB J , vol.17 , pp. 1003-1014
    • Monsinjon, T.1    Gasque, P.2    Chan, P.3    Ischenko, A.4    Brady, J.J.5    Fontaine, M.C.6
  • 68
    • 0032977170 scopus 로고    scopus 로고
    • High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome
    • Mori, M., Rothman, A. L., Kurane, I., Montoya, J. M., Nolte, K. B., Norman, J. E., et al. (1999). High levels of cytokine-producing cells in the lung tissues of patients with fatal hantavirus pulmonary syndrome. J. Infect. Dis. 179, 295-302. doi: 10.1086/314597.
    • (1999) J. Infect. Dis , vol.179 , pp. 295-302
    • Mori, M.1    Rothman, A.L.2    Kurane, I.3    Montoya, J.M.4    Nolte, K.B.5    Norman, J.E.6
  • 69
    • 84886730432 scopus 로고    scopus 로고
    • The pathogenesis of nephropathia epidemica: new knowledge and unanswered questions
    • Mustonen, J., Makela, S., Outinen, T., Laine, O., Jylhava, J., Arstila, P. T., et al. (2013). The pathogenesis of nephropathia epidemica: new knowledge and unanswered questions. Antiviral Res. 100, 589-604. doi: 10.1016/j.antiviral.2013.10.001.
    • (2013) Antiviral Res , vol.100 , pp. 589-604
    • Mustonen, J.1    Makela, S.2    Outinen, T.3    Laine, O.4    Jylhava, J.5    Arstila, P.T.6
  • 70
    • 84902653076 scopus 로고    scopus 로고
    • Neutrophils at work
    • Nauseef, W. M., and Borregaard, N. (2014). Neutrophils at work. Nat. Immunol. 15, 602-611. doi: 10.1038/ni.2921.
    • (2014) Nat. Immunol , vol.15 , pp. 602-611
    • Nauseef, W.M.1    Borregaard, N.2
  • 71
    • 0027910025 scopus 로고
    • Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness
    • Nichol, S. T., Spiropoulou, C. F., Morzunov, S., Rollin, P. E., Ksiazek, T. G., Feldmann, H., et al. (1993). Genetic identification of a hantavirus associated with an outbreak of acute respiratory illness. Science 262, 914-917. doi: 10.1126/science.8235615.
    • (1993) Science , vol.262 , pp. 914-917
    • Nichol, S.T.1    Spiropoulou, C.F.2    Morzunov, S.3    Rollin, P.E.4    Ksiazek, T.G.5    Feldmann, H.6
  • 72
    • 3142711824 scopus 로고    scopus 로고
    • Modification of endothelial cell functions by Hantaan virus infection: prolonged hyper-permeability induced by TNF-α of hantaan virus-infected endothelial cell monolayers
    • Niikura, M., Maeda, A., Ikegami, T., Saijo, M., Kurane, I., and Morikawa, S. (2004). Modification of endothelial cell functions by Hantaan virus infection: prolonged hyper-permeability induced by TNF-α of hantaan virus-infected endothelial cell monolayers. Arch. Virol. 149, 1279-1292. doi: 10.1007/s00705-004-0306-y.
    • (2004) Arch. Virol , vol.149 , pp. 1279-1292
    • Niikura, M.1    Maeda, A.2    Ikegami, T.3    Saijo, M.4    Kurane, I.5    Morikawa, S.6
  • 73
    • 0028796284 scopus 로고
    • Hantavirus pulmonary syndrome in the United States: a pathological description of a disease caused by a new agent
    • Nolte, K. B., Feddersen, R. M., Foucar, K., Zaki, S. R., Koster, F. T., Madar, D., et al. (1995). Hantavirus pulmonary syndrome in the United States: a pathological description of a disease caused by a new agent. Hum. Pathol. 26, 110-120. doi: 10.1016/0046-8177(95)90123-X.
    • (1995) Hum. Pathol , vol.26 , pp. 110-120
    • Nolte, K.B.1    Feddersen, R.M.2    Foucar, K.3    Zaki, S.R.4    Koster, F.T.5    Madar, D.6
  • 74
    • 77952295261 scopus 로고    scopus 로고
    • Modulation of apoptosis and immune signaling pathways by the Hantaan virus nucleocapsid protein
    • Ontiveros, S. J., Li, Q., and Jonsson, C. B. (2010). Modulation of apoptosis and immune signaling pathways by the Hantaan virus nucleocapsid protein. Virology 401, 165-178. doi: 10.1016/j.virol.2010.02.018.
    • (2010) Virology , vol.401 , pp. 165-178
    • Ontiveros, S.J.1    Li, Q.2    Jonsson, C.B.3
  • 75
    • 84856755961 scopus 로고    scopus 로고
    • Plasma cell-free DNA levels are elevated in acute Puumala hantavirus infection
    • Outinen, T. K., Kuparinen, T., Jylhava, J., Leppanen, S., Mustonen, J., Makela, S., et al. (2012a). Plasma cell-free DNA levels are elevated in acute Puumala hantavirus infection. PLoS ONE 7:e31455. doi: 10.1371/journal.pone.0031455.
    • (2012) PLoS ONE , vol.7
    • Outinen, T.K.1    Kuparinen, T.2    Jylhava, J.3    Leppanen, S.4    Mustonen, J.5    Makela, S.6
  • 76
    • 84863838792 scopus 로고    scopus 로고
    • High pentraxin-3 plasma levels associate with thrombocytopenia in acute Puumala hantavirus-induced nephropathia epidemica
    • Outinen, T. K., Makela, S., Huhtala, H., Hurme, M., Meri, S., Porsti, I., et al. (2012b). High pentraxin-3 plasma levels associate with thrombocytopenia in acute Puumala hantavirus-induced nephropathia epidemica. Eur. J. Clin. Microbiol. Infect. Dis. 31, 957-963. doi: 10.1007/s10096-011-1392-x.
    • (2012) Eur. J. Clin. Microbiol. Infect. Dis , vol.31 , pp. 957-963
    • Outinen, T.K.1    Makela, S.2    Huhtala, H.3    Hurme, M.4    Meri, S.5    Porsti, I.6
  • 77
    • 0033565947 scopus 로고    scopus 로고
    • Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells
    • Ozaki, H., Ishii, K., Horiuchi, H., Arai, H., Kawamoto, T., Okawa, K., et al. (1999). Cutting edge: combined treatment of TNF-α and IFN-γ causes redistribution of junctional adhesion molecule in human endothelial cells. J. Immunol. 163, 553-557.
    • (1999) J. Immunol , vol.163 , pp. 553-557
    • Ozaki, H.1    Ishii, K.2    Horiuchi, H.3    Arai, H.4    Kawamoto, T.5    Okawa, K.6
  • 78
    • 0034080577 scopus 로고    scopus 로고
    • Complement activation in nephropathia epidemica caused by Puumala hantavirus
    • Paakkala, A., Mustonen, J., Viander, M., Huhtala, H., and Pasternack, A. (2000). Complement activation in nephropathia epidemica caused by Puumala hantavirus. Clin. Nephrol. 53, 424-431.
    • (2000) Clin. Nephrol , vol.53 , pp. 424-431
    • Paakkala, A.1    Mustonen, J.2    Viander, M.3    Huhtala, H.4    Pasternack, A.5
  • 79
    • 0026731010 scopus 로고
    • Hantaan virus infection of human endothelial cells
    • Pensiero, M. N., Sharefkin, J. B., Dieffenbach, C. W., and Hay, J. (1992). Hantaan virus infection of human endothelial cells. J. Virol. 66, 5929-5936.
    • (1992) J. Virol , vol.66 , pp. 5929-5936
    • Pensiero, M.N.1    Sharefkin, J.B.2    Dieffenbach, C.W.3    Hay, J.4
  • 81
    • 84855444617 scopus 로고    scopus 로고
    • A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1
    • Pillay, J., Kamp, V. M., van, H. E., Visser, T., Tak, T., Lammers, J. W., et al. (2012). A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1. J. Clin. Invest. 122, 327-336. doi: 10.1172/JCI57990.
    • (2012) J. Clin. Invest , vol.122 , pp. 327-336
    • Pillay, J.1    Kamp, V.M.2    van, H.E.3    Visser, T.4    Tak, T.5    Lammers, J.W.6
  • 82
    • 84877261134 scopus 로고    scopus 로고
    • Endothelial activation: intracellular signaling pathways
    • Pober, J. S. (2002). Endothelial activation: intracellular signaling pathways. Arthritis Res. 4(Suppl. 3), S109-S116. doi: 10.1186/ar576.
    • (2002) Arthritis Res , vol.4 , pp. S109-S116
    • Pober, J.S.1
  • 83
    • 0036838218 scopus 로고    scopus 로고
    • Hantavirus infection of dendritic cells
    • Raftery, M. J., Kraus, A. A., Ulrich, R., Krüger, D. H., and Schönrich, G. (2002). Hantavirus infection of dendritic cells. J. Virol. 76, 10724-10733. doi: 10.1128/JVI.76.21.10724-10733.2002.
    • (2002) J. Virol , vol.76 , pp. 10724-10733
    • Raftery, M.J.1    Kraus, A.A.2    Ulrich, R.3    Krüger, D.H.4    Schönrich, G.5
  • 84
  • 85
    • 79956158572 scopus 로고    scopus 로고
    • Time to revise the paradigm of hantavirus syndromes? Hantavirus pulmonary syndrome caused by European hantavirus
    • Rasmuson, J., Andersson, C., Norrman, E., Haney, M., Evander, M., and Ahlm, C. (2011a). Time to revise the paradigm of hantavirus syndromes? Hantavirus pulmonary syndrome caused by European hantavirus. Eur. J. Clin. Microbiol. Infect. Dis. 30, 685-690. doi: 10.1007/s10096-010-1141-6.
    • (2011) Eur. J. Clin. Microbiol. Infect. Dis , vol.30 , pp. 685-690
    • Rasmuson, J.1    Andersson, C.2    Norrman, E.3    Haney, M.4    Evander, M.5    Ahlm, C.6
  • 86
    • 80052681565 scopus 로고    scopus 로고
    • Presence of activated airway T lymphocytes in human puumala hantavirus disease
    • Rasmuson, J., Pourazar, J., Linderholm, M., Sandstrom, T., Blomberg, A., and Ahlm, C. (2011b). Presence of activated airway T lymphocytes in human puumala hantavirus disease. Chest 140, 715-722. doi: 10.1378/chest.10-2791.
    • (2011) Chest , vol.140 , pp. 715-722
    • Rasmuson, J.1    Pourazar, J.2    Linderholm, M.3    Sandstrom, T.4    Blomberg, A.5    Ahlm, C.6
  • 87
    • 84877052461 scopus 로고    scopus 로고
    • Crossing the wall: the opening of endothelial cell junctions during infectious diseases
    • Razakandrainibe, R., Combes, V., Grau, G. E., and Jambou, R. (2013). Crossing the wall: the opening of endothelial cell junctions during infectious diseases. Int. J. Biochem. Cell Biol. 45, 1165-1173. doi: 10.1016/j.biocel.2013.03.010.
    • (2013) Int. J. Biochem. Cell Biol , vol.45 , pp. 1165-1173
    • Razakandrainibe, R.1    Combes, V.2    Grau, G.E.3    Jambou, R.4
  • 89
    • 81055148242 scopus 로고    scopus 로고
    • Cytokine expression during early and late phase of acute Puumala hantavirus infection
    • Sadeghi, M., Eckerle, I., Daniel, V., Burkhardt, U., Opelz, G., and Schnitzler, P. (2011). Cytokine expression during early and late phase of acute Puumala hantavirus infection. BMC Immunol. 12:65. doi: 10.1186/1471-2172-12-65.
    • (2011) BMC Immunol , vol.12 , pp. 65
    • Sadeghi, M.1    Eckerle, I.2    Daniel, V.3    Burkhardt, U.4    Opelz, G.5    Schnitzler, P.6
  • 90
    • 84857591047 scopus 로고    scopus 로고
    • Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones
    • Saffarzadeh, M., Juenemann, C., Queisser, M. A., Lochnit, G., Barreto, G., Galuska, S. P., et al. (2012). Neutrophil extracellular traps directly induce epithelial and endothelial cell death: a predominant role of histones. PLoS ONE 7:e32366. doi: 10.1371/journal.pone.0032366.
    • (2012) PLoS ONE , vol.7
    • Saffarzadeh, M.1    Juenemann, C.2    Queisser, M.A.3    Lochnit, G.4    Barreto, G.5    Galuska, S.P.6
  • 91
    • 84921903158 scopus 로고    scopus 로고
    • Birth and pathogenesis of rogue respiratory viruses
    • Safronetz, D., Feldmann, H., and de, W. E. (2015). Birth and pathogenesis of rogue respiratory viruses. Annu. Rev. Pathol. 10, 449-471. doi: 10.1146/annurev-pathol-012414-040501.
    • (2015) Annu. Rev. Pathol , vol.10 , pp. 449-471
    • Safronetz, D.1    Feldmann, H.2    de, W.E.3
  • 92
    • 79956206897 scopus 로고    scopus 로고
    • Serum levels of inflammatory and regulatory cytokines in patients with hemorrhagic fever with renal syndrome
    • Saksida, A., Wraber, B., and Avsic-Zupanc, T. (2011). Serum levels of inflammatory and regulatory cytokines in patients with hemorrhagic fever with renal syndrome. BMC Infect. Dis. 11:142. doi: 10.1186/1471-2334-11-142.
    • (2011) BMC Infect. Dis , vol.11 , pp. 142
    • Saksida, A.1    Wraber, B.2    Avsic-Zupanc, T.3
  • 93
    • 84864058294 scopus 로고    scopus 로고
    • Complement activation in Puumala hantavirus infection correlates with disease severity
    • Sane, J., Laine, O., Makela, S., Paakkala, A., Jarva, H., Mustonen, J., et al. (2012). Complement activation in Puumala hantavirus infection correlates with disease severity. Ann. Med. 44, 468-475. doi: 10.3109/07853890.2011.573500.
    • (2012) Ann. Med , vol.44 , pp. 468-475
    • Sane, J.1    Laine, O.2    Makela, S.3    Paakkala, A.4    Jarva, H.5    Mustonen, J.6
  • 94
    • 77956297223 scopus 로고    scopus 로고
    • Vaccines for hantaviruses
    • Schmaljohn, C. (2009). Vaccines for hantaviruses. Vaccine 27(Suppl. 4), D61-D64. doi: 10.1016/j.vaccine.2009.07.096.
    • (2009) Vaccine , vol.27 , pp. D61-D64
    • Schmaljohn, C.1
  • 95
    • 34948862521 scopus 로고    scopus 로고
    • 'Bunyaviridae'
    • eds D. M. Knipe and P. M. Howley (Philadelphia, PA: Lippincott Williams & Wilkins)
    • Schmaljohn, C. S., and Nichol, S. T. (2007). "Bunyaviridae, "in Fields Virology, eds D. M. Knipe and P. M. Howley (Philadelphia, PA: Lippincott Williams & Wilkins), 1741-1789.
    • (2007) Fields Virology , pp. 1741-1789
    • Schmaljohn, C.S.1    Nichol, S.T.2
  • 96
  • 97
    • 80054935637 scopus 로고    scopus 로고
    • Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability
    • Schulte, D., Kuppers, V., Dartsch, N., Broermann, A., Li, H., Zarbock, A., et al. (2011). Stabilizing the VE-cadherin-catenin complex blocks leukocyte extravasation and vascular permeability. EMBO J. 30, 4157-4170. doi: 10.1038/emboj.2011.304.
    • (2011) EMBO J , vol.30 , pp. 4157-4170
    • Schulte, D.1    Kuppers, V.2    Dartsch, N.3    Broermann, A.4    Li, H.5    Zarbock, A.6
  • 98
    • 84868124022 scopus 로고    scopus 로고
    • Distinct innate immune responses in human macrophages and endothelial cells infected with shrew-borne hantaviruses
    • Shin, O. S., Yanagihara, R., and Song, J. W. (2012). Distinct innate immune responses in human macrophages and endothelial cells infected with shrew-borne hantaviruses. Virology 434, 43-49. doi: 10.1016/j.virol.2012.08.004.
    • (2012) Virology , vol.434 , pp. 43-49
    • Shin, O.S.1    Yanagihara, R.2    Song, J.W.3
  • 99
    • 77957940689 scopus 로고    scopus 로고
    • Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin
    • Shrivastava-Ranjan, P., Rollin, P. E., and Spiropoulou, C. F. (2010). Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin. J. Virol. 84, 11227-11234. doi: 10.1128/JVI.01405-10.
    • (2010) J. Virol , vol.84 , pp. 11227-11234
    • Shrivastava-Ranjan, P.1    Rollin, P.E.2    Spiropoulou, C.F.3
  • 100
    • 0034974905 scopus 로고    scopus 로고
    • Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells
    • Sundstrom, J. B., McMullan, L. K., Spiropoulou, C. F., Hooper, W. C., Ansari, A. A., Peters, C. J., et al. (2001). Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells. J. Virol. 75, 6070-6085. doi: 10.1128/JVI.75.13.6070-6085.2001.
    • (2001) J. Virol , vol.75 , pp. 6070-6085
    • Sundstrom, J.B.1    McMullan, L.K.2    Spiropoulou, C.F.3    Hooper, W.C.4    Ansari, A.A.5    Peters, C.J.6
  • 102
    • 59749104967 scopus 로고    scopus 로고
    • Hantaan virus nucleocapsid protein binds to importin a proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B
    • Taylor, S. L., Frias-Staheli, N., Garcia-Sastre, A., and Schmaljohn, C. S. (2009). Hantaan virus nucleocapsid protein binds to importin a proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B. J. Virol. 83, 1271-1279. doi: 10.1128/JVI.00986-08.
    • (2009) J. Virol , vol.83 , pp. 1271-1279
    • Taylor, S.L.1    Frias-Staheli, N.2    Garcia-Sastre, A.3    Schmaljohn, C.S.4
  • 103
    • 84884777032 scopus 로고    scopus 로고
    • Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system
    • Taylor, S. L., Wahl-Jensen, V., Copeland, A. M., Jahrling, P. B., and Schmaljohn, C. S. (2013). Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system. PLoS. Pathog. 9:e1003470. doi: 10.1371/journal.ppat.1003470.
    • (2013) PLoS. Pathog , vol.9
    • Taylor, S.L.1    Wahl-Jensen, V.2    Copeland, A.M.3    Jahrling, P.B.4    Schmaljohn, C.S.5
  • 104
    • 0029875112 scopus 로고    scopus 로고
    • Cytokines, adhesion molecules, and cellular infiltration in nephropathia epidemica kidneys: an immunohistochemical study
    • Temonen, M., Mustonen, J., Helin, H., Pasternack, A., Vaheri, A., and Holthofer, H. (1996). Cytokines, adhesion molecules, and cellular infiltration in nephropathia epidemica kidneys: an immunohistochemical study. Clin. Immunol. Immunopathol. 78, 47-55. doi: 10.1006/clin.1996.0007.
    • (1996) Clin. Immunol. Immunopathol , vol.78 , pp. 47-55
    • Temonen, M.1    Mustonen, J.2    Helin, H.3    Pasternack, A.4    Vaheri, A.5    Holthofer, H.6
  • 106
    • 79960781684 scopus 로고    scopus 로고
    • T cells and pathogenesis of hantavirus cardiopulmonary syndrome and hemorrhagic fever with renal syndrome
    • Terajima, M., and Ennis, F. A. (2011). T cells and pathogenesis of hantavirus cardiopulmonary syndrome and hemorrhagic fever with renal syndrome. Viruses 3, 1059-1073. doi: 10.3390/v3071059.
    • (2011) Viruses , vol.3 , pp. 1059-1073
    • Terajima, M.1    Ennis, F.A.2
  • 107
    • 0028244816 scopus 로고
    • Tumor necrosis factor: a pleiotropic cytokine and therapeutic target
    • Tracey, K. J., and Cerami, A. (1994). Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 45, 491-503. doi: 10.1146/annurev.med.45.1.491.
    • (1994) Annu. Rev. Med , vol.45 , pp. 491-503
    • Tracey, K.J.1    Cerami, A.2
  • 108
    • 84907494075 scopus 로고    scopus 로고
    • Pathophysiology of a severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant
    • Vaheri, A., Strandin, T., Jaaskelainen, A. J., Vapalahti, O., Jarva, H., Lokki, M. L., et al. (2014). Pathophysiology of a severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant. Antiviral Res. 111C, 23-25. doi: 10.1016/j.antiviral.2014.08.007.
    • (2014) Antiviral Res , vol.111 C , pp. 23-25
    • Vaheri, A.1    Strandin, T.2    Jaaskelainen, A.J.3    Vapalahti, O.4    Jarva, H.5    Lokki, M.L.6
  • 109
    • 84884377717 scopus 로고    scopus 로고
    • High-dose intravenous methylprednisolone for hantavirus cardiopulmonary syndrome in Chile: a double-blind, randomized controlled clinical trial
    • Vial, P. A., Valdivieso, F., Ferres, M., Riquelme, R., Rioseco, M. L., Calvo, M., et al. (2013). High-dose intravenous methylprednisolone for hantavirus cardiopulmonary syndrome in Chile: a double-blind, randomized controlled clinical trial. Clin. Infect. Dis. 57, 943-951. doi: 10.1093/cid/cit394.
    • (2013) Clin. Infect. Dis , vol.57 , pp. 943-951
    • Vial, P.A.1    Valdivieso, F.2    Ferres, M.3    Riquelme, R.4    Rioseco, M.L.5    Calvo, M.6
  • 110
    • 79960392810 scopus 로고    scopus 로고
    • Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus
    • Villanueva, E., Yalavarthi, S., Berthier, C. C., Hodgin, J. B., Khandpur, R., Lin, A. M., et al. (2011). Netting neutrophils induce endothelial damage, infiltrate tissues, and expose immunostimulatory molecules in systemic lupus erythematosus. J. Immunol. 187, 538-552. doi: 10.4049/jimmunol.1100450.
    • (2011) J. Immunol , vol.187 , pp. 538-552
    • Villanueva, E.1    Yalavarthi, S.2    Berthier, C.C.3    Hodgin, J.B.4    Khandpur, R.5    Lin, A.M.6
  • 111
    • 0031874051 scopus 로고    scopus 로고
    • Implications of the analogy between recombinant cytokine toxicities and manifestations of hantavirus infections
    • Wimer, B. M. (1998). Implications of the analogy between recombinant cytokine toxicities and manifestations of hantavirus infections. Cancer Biother. Radiopharm. 13, 193-207. doi: 10.1089/cbr.1998.13.193.
    • (1998) Cancer Biother. Radiopharm , vol.13 , pp. 193-207
    • Wimer, B.M.1
  • 112
    • 70449107044 scopus 로고    scopus 로고
    • Extracellular histones are major mediators of death in sepsis
    • Xu, J., Zhang, X., Pelayo, R., Monestier, M., Ammollo, C. T., Semeraro, F., et al. (2009). Extracellular histones are major mediators of death in sepsis. Nat. Med. 15, 1318-1321. doi: 10.1038/nm.2053.
    • (2009) Nat. Med , vol.15 , pp. 1318-1321
    • Xu, J.1    Zhang, X.2    Pelayo, R.3    Monestier, M.4    Ammollo, C.T.5    Semeraro, F.6
  • 113
    • 84899531922 scopus 로고    scopus 로고
    • Involvement of the Akt/NF-κB pathways in the HTNV-mediated increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs
    • Yu, H., Jiang, W., Du, H., Xing, Y., Bai, G., Zhang, Y., et al. (2014). Involvement of the Akt/NF-κB pathways in the HTNV-mediated increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs. PLoS ONE 9:e93810. doi: 10.1371/journal.pone.0093810.
    • (2014) PLoS ONE , vol.9
    • Yu, H.1    Jiang, W.2    Du, H.3    Xing, Y.4    Bai, G.5    Zhang, Y.6
  • 114
  • 115
    • 84903433037 scopus 로고    scopus 로고
    • The role of platelets in the pathogenesis of viral hemorrhagic fevers
    • Zapata, J. C., Cox, D., and Salvato, M. S. (2014). The role of platelets in the pathogenesis of viral hemorrhagic fevers. PLoS Negl. Trop. Dis. 8:e2858. doi: 10.1371/journal.pntd.0002858.
    • (2014) PLoS Negl. Trop. Dis , vol.8
    • Zapata, J.C.1    Cox, D.2    Salvato, M.S.3
  • 116
    • 84887001586 scopus 로고    scopus 로고
    • Tula hantavirus infection in immunocompromised host, Czech Republic
    • Zelena, H., Mrazek, J., and Kuhn, T. (2013). Tula hantavirus infection in immunocompromised host, Czech Republic. Emerg. Infect. Dis. 19, 1873-1875. doi: 10.3201/eid1911.130421.
    • (2013) Emerg. Infect. Dis , vol.19 , pp. 1873-1875
    • Zelena, H.1    Mrazek, J.2    Kuhn, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.