Mechanisms of antibiotic resistance

Frontiers in Microbiology

Volumn 6, Issue FEB, 2015, Pages

  Lin, Jun ^a   Nishino, Kunihiko ^b   Roberts, Marilyn C ^c   Tolmasky, Marcelo ^d   Aminov, Rustam I ^e   Zhang, Lixin ^f  

^a UNIVERSITY OF TENNESSEE   (United States)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF WASHINGTON   (United States)

^d CALIFORNIA STATE UNIVERSITY   (United States)

^e TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^f INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Antibiotics; Combination therapy; Mechanisms; Metagenomics; Resistance; Resistance reservoirs

Indexed keywords

ANTIBIOTIC RESISTANCE; ECOSYSTEM; EDITORIAL; GENE; GENE DOSAGE; GENE EXPRESSION; GENOMICS; HIGH THROUGHPUT SEQUENCING; HUMAN; NONHUMAN; PATHOGENESIS; TRANSCRIPTION REGULATION;

EID: 84927561023     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00034     Document Type: Editorial

References (27)

1. Abbes, S., Mary, C., Sellami, H., Michel-Nguyen, A., Ayadi, A., and Ranque, S. (2013). Interactions between copy number and expression level of genes involved in fluconazole resistance in Candida glabrata. Front. Cell. Infect. Microbiol. 3:74. doi: 10.3389/fcimb.2013.00074.
2. Baucheron, S., Monchaux, I., Le, H. S., Weill, F. X., and Cloeckaert, A. (2014). Lack of efflux mediated quinolone resistance in Salmonella enterica serovars Typhi and Paratyphi A. Front. Microbiol. 5:12. doi: 10.3389/fmicb.2014.00012.
3. Burch, T. R., Sadowsky, M. J., and Lapara, T. M. (2013). Aerobic digestion reduces the quantity of antibiotic resistance genes in residual municipal wastewater solids. Front. Microbiol. 4:17. doi: 10.3389/fmicb.2013.00017.
4. Chuma, T., Miyasako, D., Dahshan, H., Takayama, T., Nakamoto, Y., Shahada, F., et al. (2013). Chronological change of resistance to beta-Lactams in Salmonella enterica serovar infantis isolated from broilers in Japan. Front. Microbiol. 4:113. doi: 10.3389/fmicb.2013.00113.
5. Deng, Z., Shan, Y., Pan, Q., Gao, X., and Yan, A. (2013). Anaerobic expression of thegadE-mdtEF multidrug efflux operon is primarily regulated by the two-component system ArcBA through antagonizing the H-NS mediated repression. Front. Microbiol. 4:194. doi: 10.3389/fmicb.2013.00194.
6. Fahrenfeld, N., Ma, Y., O'Brien, M., and Pruden, A. (2013). Reclaimed water as a reservoir of antibiotic resistance genes: distribution system and irrigation implications. Front. Microbiol. 4:130. doi: 10.3389/fmicb.2013.00130.
7. Green, K. D., and Garneau-Tsodikova, S. (2013). Resistance in tuberculosis: what do we know and where can we go? Front. Microbiol. 4:208. doi: 10.3389/fmicb.2013.00208.
8. Hirakawa, H., and Tomita, H. (2013). Interference of bacterial cell-to-cell communication: a new concept of antimicrobial chemotherapy breaks antibiotic resistance. Front. Microbiol. 4:114. doi: 10.3389/fmicb.2013.00114.
9. Iino, R., Matsumoto, Y., Nishino, K., Yamaguchi, A., and Noji, H. (2013). Design of a large-scale femtoliter droplet array for single-cell analysis of drug-tolerant and drug-resistant bacteria. Front. Microbiol. 4:300. doi: 10.3389/fmicb.2013.00300.
10. Ilina, E. N., Malakhova, M. V., Bodoev, I. N., Oparina, N. Y., Filimonova, A. V., and Govorun, V. M. (2013). Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae. Front. Microbiol. 4:186. doi: 10.3389/fmicb.2013.00186.
11. Kaplan, E., Ofek, M., Jurkevitch, E., and Cytryn, E. (2013). Characterization of fluoroquinolone resistance and qnr diversity in Enterobacteriaceae from municipal biosolids. Front. Microbiol. 4:144. doi: 10.3389/fmicb.2013.00144.
12. Miranda, C. D., Tello, A., and Keen, P. L. (2013). Mechanisms of antimicrobial resistance in finfish aquaculture environments. Front. Microbiol. 4:233. doi: 10.3389/fmicb.2013.00233.
13. Morita, Y., Tomida, J., and Kawamura, Y. (2012). MexXY multidrug efflux system of Pseudomonas aeruginosa. Front. Microbiol. 3:408. doi: 10.3389/fmicb.2012.00408.
14. Nosanchuk, J. D., Lin, J., Hunter, R. P., and Aminov, R. I. (2014). Low-dose antibiotics: current status and outlook for the future. Front. Microbiol. 5:478. doi: 10.3389/fmicb.2014.00478.
15. Olivares, J., Bernardini, A., Garcia-Leon, G., Corona, F., Sanchez, B., and Martinez, J. L. (2013). The intrinsic resistome of bacterial pathogens. Front. Microbiol. 4:103. doi: 10.3389/fmicb.2013.00103.
16. Pehrsson, E. C., Forsberg, K. J., Gibson, M. K., Ahmadi, S., and Dantas, G. (2013). Novel resistance functions uncovered using functional metagenomic investigations of resistance reservoirs. Front. Microbiol. 4:145. doi: 10.3389/fmicb.2013.00145.
17. Perry, J. A., and Wright, G. D. (2013). The antibiotic resistance "mobilome": searching for the link between environment and clinic. Front. Microbiol. 4:138. doi: 10.3389/fmicb.2013.00138.
18. Ramirez, M. S., Nikolaidis, N., and Tolmasky, M. E. (2013). Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm. Front. Microbiol. 4:121. doi: 10.3389/fmicb.2013.00121.
19. Roberts, M. C., Soge, O. O., and No, D. (2013). Comparison of multi-drug resistant environmental methicillin-resistant Staphylococcus aureus isolated from recreational beaches and high touch surfaces in built environments. Front. Microbiol. 4:74. doi: 10.3389/fmicb.2013.00074.
20. Shi, K., Caldwell, S. J., Fong, D. H., and Berghuis, A. M. (2013). Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance. Front. Cell. Infect. Microbiol. 3:22. doi: 10.3389/fcimb.2013.00022.
21. Sun, X., Wang, W., Wang, K., Yu, X., Liu, J., Zhou, F., et al. (2013). Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides. Front. Microbiol. 4:127. doi: 10.3389/fmicb.2013.00127.
22. Suzuki, S., Ogo, M., Miller, T. W., Shimizu, A., Takada, H., and Siringan, M. A. (2013). Who possesses drug resistance genes in the aquatic environment?: sulfamethoxazole (SMX) resistance genes among the bacterial community in water environment of Metro-Manila, Philippines. Front. Microbiol. 4:102. doi: 10.3389/fmicb.2013.00102.
23. Usui, M., Nagai, H., Hiki, M., Tamura, Y., and Asai, T. (2013). Effect of antimicrobial exposure on AcrAB Expression in Salmonella enterica subspecies enterica serovar choleraesuis. Front. Microbiol. 4:53. doi: 10.3389/fmicb.2013.00053.
24. Watkins, R. R., Papp-Wallace, K. M., Drawz, S. M., and Bonomo, R. A. (2013). Novel beta-lactamase inhibitors: a therapeutic hope against the scourge of multidrug resistance. Front. Microbiol. 4:392. doi: 10.3389/fmicb.2013.00392.
25. Zaheer, R., Cook, S. R., Klima, C. L., Stanford, K., Alexander, T., Topp, E., et al. (2013). Effect of subtherapeutic vs. therapeutic administration of macrolides on antimicrobial resistance in Mannheimia haemolytica and enterococci isolated from beef cattle. Front. Microbiol. 4:133. doi: 10.3389/fmicb.2013.00133.
26. Zeng, X., and Lin, J. (2013). Beta-lactamase induction and cell wall metabolism in Gram-negative bacteria. Front. Microbiol. 4:128. doi: 10.3389/fmicb.2013.00128.
27. Zhang, L., Yan, K., Zhang, Y., Bian, J., Zheng, C., Sun, H., et al. (2007). High-throughput synergy screening identifies microbial metabolites as combination agents for the treatment of fungal infections. Proc. Natl. Acad. Sci. U.S.A. 104, 4606-4611. doi: 10.1073/pnas.0609370104.