-
1
-
-
84879588228
-
Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)
-
Sharpe, L. J., and A. J. Brown. 2013. Controlling cholesterol synthesis beyond 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR). J. Biol. Chem. 288: 18707-18715.
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 18707-18715
-
-
Sharpe, L.J.1
Brown, A.J.2
-
2
-
-
0002380192
-
The biological synthesis of cholesterol
-
Bloch, K. 1965. The biological synthesis of cholesterol. Science. 150: 19-28.
-
(1965)
Science
, vol.150
, pp. 19-28
-
-
Bloch, K.1
-
3
-
-
0001415416
-
Preputial gland tumor sterols. 3. A metabolic pathway from lanosterol to cholesterol
-
Kandutsch, A. A., and A. E. Russell. 1960. Preputial gland tumor sterols. 3. A metabolic pathway from lanosterol to cholesterol. J. Biol. Chem. 235: 2256-2261.
-
(1960)
J. Biol. Chem.
, vol.235
, pp. 2256-2261
-
-
Kandutsch, A.A.1
Russell, A.E.2
-
4
-
-
43949129429
-
Differential effects of cholesterol and its immediate biosynthetic precursors on membrane organization
-
Shrivastava, S., Y. D. Paila, A. Dutta, and A. Chattopadhyay. 2008. Differential effects of cholesterol and its immediate biosynthetic precursors on membrane organization. Biochemistry. 47: 5668-5677.
-
(2008)
Biochemistry
, vol.47
, pp. 5668-5677
-
-
Shrivastava, S.1
Paila, Y.D.2
Dutta, A.3
Chattopadhyay, A.4
-
5
-
-
77954762640
-
Origin of 7-dehydrocholesterol (provitamin D) in the skin
-
Glossmann, H. H. 2010. Origin of 7-dehydrocholesterol (provitamin D) in the skin. J. Invest. Dermatol. 130: 2139-2141.
-
(2010)
J. Invest. Dermatol.
, vol.130
, pp. 2139-2141
-
-
Glossmann, H.H.1
-
6
-
-
33644555054
-
Proteome survey reveals modularity of the yeast cell machinery
-
Gavin, A. C., P. Aloy, P. Grandi, R. Krause, M. Boesche, M. Marzioch, C. Rau, L. J. Jensen, S. Bastuck, B. Dumpelfeld, et al. 2006. Proteome survey reveals modularity of the yeast cell machinery. Nature. 440: 631-636.
-
(2006)
Nature
, vol.440
, pp. 631-636
-
-
Gavin, A.C.1
Aloy, P.2
Grandi, P.3
Krause, R.4
Boesche, M.5
Marzioch, M.6
Rau, C.7
Jensen, L.J.8
Bastuck, S.9
Dumpelfeld, B.10
-
7
-
-
28444485988
-
A systematic study of yeast sterol biosynthetic protein-protein interactions using the split-ubiquitin system
-
Mo, C., and M. Bard. 2005. A systematic study of yeast sterol biosynthetic protein-protein interactions using the split-ubiquitin system. Biochim. Biophys. Acta. 1737: 152-160.
-
(2005)
Biochim. Biophys. Acta
, vol.1737
, pp. 152-160
-
-
Mo, C.1
Bard, M.2
-
8
-
-
84755160716
-
Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts
-
Taramino, S., B. Teske, S. Oliaro-Bosso, M. Bard, and G. Balliano. 2010. Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts. Biochim. Biophys. Acta. 1801: 1232-1237.
-
(2010)
Biochim. Biophys. Acta
, vol.1801
, pp. 1232-1237
-
-
Taramino, S.1
Teske, B.2
Oliaro-Bosso, S.3
Bard, M.4
Balliano, G.5
-
9
-
-
34250345292
-
Confirmation of organized modularity in the yeast interactome
-
Bertin, N., N. Simonis, D. Dupuy, M. E. Cusick, J. D. Han, H. B. Fraser, F. P. Roth, and M. Vidal. 2007. Confirmation of organized modularity in the yeast interactome. PLoS Biol. 5: e153.
-
(2007)
PLoS Biol.
, vol.5
, pp. e153
-
-
Bertin, N.1
Simonis, N.2
Dupuy, D.3
Cusick, M.E.4
Han, J.D.5
Fraser, H.B.6
Roth, F.P.7
Vidal, M.8
-
10
-
-
84859222354
-
The methylproteome and the intracellular methylation network
-
Erce, M. A., C. N. Pang, G. Hart-Smith, and M. R. Wilkins. 2012. The methylproteome and the intracellular methylation network. Proteomics. 12: 564-586.
-
(2012)
Proteomics
, vol.12
, pp. 564-586
-
-
Erce, M.A.1
Pang, C.N.2
Hart-Smith, G.3
Wilkins, M.R.4
-
11
-
-
0034741599
-
Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis
-
Waterham, H. R., J. Koster, G. J. Romeijn, R. C. Hennekam, P. Vreken, H. C. Andersson, D. R. FitzPatrick, R. I. Kelley, and R. J. Wanders. 2001. Mutations in the 3beta-hydroxysterol Delta24-reductase gene cause desmosterolosis, an autosomal recessive disorder of cholesterol biosynthesis. Am. J. Hum. Genet. 69: 685-694.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 685-694
-
-
Waterham, H.R.1
Koster, J.2
Romeijn, G.J.3
Hennekam, R.C.4
Vreken, P.5
Andersson, H.C.6
FitzPatrick, D.R.7
Kelley, R.I.8
Wanders, R.J.9
-
12
-
-
0032539605
-
Molecular cloning and expression of the human delta7-sterol reductase
-
Moebius, F. F., B. U. Fitzky, J. N. Lee, Y. K. Paik, and H. Glossmann. 1998. Molecular cloning and expression of the human delta7-sterol reductase. Proc. Natl. Acad. Sci. USA. 95: 1899-1902.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1899-1902
-
-
Moebius, F.F.1
Fitzky, B.U.2
Lee, J.N.3
Paik, Y.K.4
Glossmann, H.5
-
13
-
-
84885551715
-
Desmosterol and DHCR24: Unexpected new directions for a terminal step in cholesterol synthesis
-
Zerenturk, E. J., L. J. Sharpe, E. Ikonen, and A. J. Brown. 2013. Desmosterol and DHCR24: unexpected new directions for a terminal step in cholesterol synthesis. Prog. Lipid Res. 52: 666-680.
-
(2013)
Prog. Lipid Res.
, vol.52
, pp. 666-680
-
-
Zerenturk, E.J.1
Sharpe, L.J.2
Ikonen, E.3
Brown, A.J.4
-
14
-
-
0031983989
-
Clinical phenotype of desmosterolosis
-
FitzPatrick, D. R., J. W. Keeling, M. J. Evans, A. E. Kan, J. E. Bell, M. E. Porteous, K. Mills, R. M. Winter, and P. T. Clayton. 1998. Clinical phenotype of desmosterolosis. Am. J. Med. Genet. 75: 145-152.
-
(1998)
Am. J. Med. Genet.
, vol.75
, pp. 145-152
-
-
FitzPatrick, D.R.1
Keeling, J.W.2
Evans, M.J.3
Kan, A.E.4
Bell, J.E.5
Porteous, M.E.6
Mills, K.7
Winter, R.M.8
Clayton, P.T.9
-
15
-
-
0024971244
-
Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells
-
Metherall, J. E., J. L. Goldstein, K. L. Luskey, and M. S. Brown. 1989. Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells. J. Biol. Chem. 264: 15634-15641.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 15634-15641
-
-
Metherall, J.E.1
Goldstein, J.L.2
Luskey, K.L.3
Brown, M.S.4
-
16
-
-
0020973547
-
Receptor-mediated endocytosis of low-density lipoprotein in cultured cells
-
Goldstein, J. L., S. K. Basu, and M. S. Brown. 1983. Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. Methods Enzymol. 98: 241-260.
-
(1983)
Methods Enzymol.
, vol.98
, pp. 241-260
-
-
Goldstein, J.L.1
Basu, S.K.2
Brown, M.S.3
-
17
-
-
77949510089
-
Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3
-
Krycer, J. R., I. Kristiana, and A. J. Brown. 2009. Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3. PLoS ONE. 4: e8496.
-
(2009)
PLoS ONE
, vol.4
, pp. e8496
-
-
Krycer, J.R.1
Kristiana, I.2
Brown, A.J.3
-
18
-
-
0036671360
-
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism
-
Brown, A. J., L. Sun, J. D. Feramisco, M. S. Brown, and J. L. Goldstein. 2002. Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism. Mol. Cell. 10: 237-245.
-
(2002)
Mol. Cell
, vol.10
, pp. 237-245
-
-
Brown, A.J.1
Sun, L.2
Feramisco, J.D.3
Brown, M.S.4
Goldstein, J.L.5
-
19
-
-
84863983024
-
The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (seladin-1)
-
Zerenturk, E. J., I. Kristiana, S. Gill, and A. J. Brown. 2012. The endogenous regulator 24(S),25-epoxycholesterol inhibits cholesterol synthesis at DHCR24 (seladin-1). Biochim. Biophys. Acta. 1821: 1269-1277.
-
(2012)
Biochim. Biophys. Acta
, vol.1821
, pp. 1269-1277
-
-
Zerenturk, E.J.1
Kristiana, I.2
Gill, S.3
Brown, A.J.4
-
20
-
-
40649107834
-
A novel megaprimed and ligase-free, PCR-based, site-directed mutagenesis method
-
Tseng, W. C., J. W. Lin, T. Y. Wei, and T. Y. Fang. 2008. A novel megaprimed and ligase-free, PCR-based, site-directed mutagenesis method. Anal. Biochem. 375: 376-378.
-
(2008)
Anal. Biochem.
, vol.375
, pp. 376-378
-
-
Tseng, W.C.1
Lin, J.W.2
Wei, T.Y.3
Fang, T.Y.4
-
21
-
-
84855808743
-
Akt acutely activates the cholesterogenic transcription factor SREBP-2
-
Luu, W., L. J. Sharpe, J. Stevenson, and A. J. Brown. 2012. Akt acutely activates the cholesterogenic transcription factor SREBP-2. Biochim. Biophys. Acta. 1823: 458-464.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 458-464
-
-
Luu, W.1
Sharpe, L.J.2
Stevenson, J.3
Brown, A.J.4
-
22
-
-
84894720321
-
Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis
-
Luu, W., E. J. Zerenturk, I. Kristiana, M. P. Bucknall, L. J. Sharpe, and A. J. Brown. 2014. Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis. J. Lipid Res. 55: 410-420.
-
(2014)
J. Lipid Res.
, vol.55
, pp. 410-420
-
-
Luu, W.1
Zerenturk, E.J.2
Kristiana, I.3
Bucknall, M.P.4
Sharpe, L.J.5
Brown, A.J.6
-
23
-
-
84861498444
-
Is seladin-1 really a selective Alzheimer's disease indicator?
-
Sharpe, L. J., J. Wong, B. Garner, G. M. Halliday, and A. J. Brown. 2012. Is seladin-1 really a selective Alzheimer's disease indicator? J. Alzheimers Dis. 30: 35-39.
-
(2012)
J. Alzheimers Dis.
, vol.30
, pp. 35-39
-
-
Sharpe, L.J.1
Wong, J.2
Garner, B.3
Halliday, G.M.4
Brown, A.J.5
-
24
-
-
84905165960
-
The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis
-
Prabhu, A. V., L. J. Sharpe, and A. J. Brown. 2014. The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis. Biochim. Biophys. Acta. 1842: 1431-1439.
-
(2014)
Biochim. Biophys. Acta
, vol.1842
, pp. 1431-1439
-
-
Prabhu, A.V.1
Sharpe, L.J.2
Brown, A.J.3
-
25
-
-
33744732467
-
Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: A link between a key cell proliferative pathway and membrane synthesis
-
Du, X., I. Kristiana, J. Wong, and A. J. Brown. 2006. Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis. Mol. Biol. Cell. 17: 2735-2745.
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 2735-2745
-
-
Du, X.1
Kristiana, I.2
Wong, J.3
Brown, A.J.4
-
26
-
-
0035202091
-
Rapid quantification of human ABCA1 mRNA in various cell types and tissues by real-time reverse transcription-PCR
-
Kielar, D., W. Dietmaier, T. Langmann, C. Aslanidis, M. Probst, M. Naruszewicz, and G. Schmitz. 2001. Rapid quantification of human ABCA1 mRNA in various cell types and tissues by real-time reverse transcription-PCR. Clin. Chem. 47: 2089-2097.
-
(2001)
Clin. Chem.
, vol.47
, pp. 2089-2097
-
-
Kielar, D.1
Dietmaier, W.2
Langmann, T.3
Aslanidis, C.4
Probst, M.5
Naruszewicz, M.6
Schmitz, G.7
-
27
-
-
0029927505
-
Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
-
Shevchenko, A., M. Wilm, O. Vorm, and M. Mann. 1996. Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal. Chem. 68: 850-858.
-
(1996)
Anal. Chem.
, vol.68
, pp. 850-858
-
-
Shevchenko, A.1
Wilm, M.2
Vorm, O.3
Mann, M.4
-
28
-
-
84856152416
-
Detection and characterization of low abundance glycopeptides via higher-energy C-trap dissociation and orbitrap mass analysis
-
Hart-Smith, G., and M. J. Raftery. 2012. Detection and characterization of low abundance glycopeptides via higher-energy C-trap dissociation and orbitrap mass analysis. J. Am. Soc. Mass Spectrom. 23: 124-140.
-
(2012)
J. Am. Soc. Mass Spectrom.
, vol.23
, pp. 124-140
-
-
Hart-Smith, G.1
Raftery, M.J.2
-
29
-
-
84891767394
-
RefSeq: An update on mammalian reference sequences
-
Pruitt, K. D., G. R. Brown, S. M. Hiatt, F. Thibaud-Nissen, A. Astashyn, O. Ermolaeva, C. M. Farrell, J. Hart, M. J. Landrum, K. M. McGarvey, et al. 2014. RefSeq: an update on mammalian reference sequences. Nucleic Acids Res. 42: D756-763.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D756-D763
-
-
Pruitt, K.D.1
Brown, G.R.2
Hiatt, S.M.3
Thibaud-Nissen, F.4
Astashyn, A.5
Ermolaeva, O.6
Farrell, C.M.7
Hart, J.8
Landrum, M.J.9
McGarvey, K.M.10
-
30
-
-
0024829036
-
The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction
-
Tabas, I., S. J. Feinmark, and N. Beatini. 1989. The reactivity of desmosterol and other shellfish- and xanthomatosis-associated sterols in the macrophage sterol esterification reaction. J. Clin. Invest. 84: 1713-1721.
-
(1989)
J. Clin. Invest.
, vol.84
, pp. 1713-1721
-
-
Tabas, I.1
Feinmark, S.J.2
Beatini, N.3
-
31
-
-
84927526834
-
Rapid suppression of 7-dehydrocholesterol reductase activity in keratinocytes by vitamin D
-
In press
-
Zou, L., and T. D. Porter. 2014. Rapid suppression of 7-dehydrocholesterol reductase activity in keratinocytes by vitamin D. J. Steroid Biochem. Mol. Biol. In press.
-
(2014)
J. Steroid Biochem. Mol. Biol.
-
-
Zou, L.1
Porter, T.D.2
-
32
-
-
84907868470
-
The structural and functional coordination of glycolytic enzymes in muscle: Evidence of a metabolon?
-
Menard, L., D. Maughan, and J. Vigoreaux. 2014. The structural and functional coordination of glycolytic enzymes in muscle: evidence of a metabolon? Biology (Basel). 3: 623-644.
-
(2014)
Biology (Basel)
, vol.3
, pp. 623-644
-
-
Menard, L.1
Maughan, D.2
Vigoreaux, J.3
-
33
-
-
78650528801
-
Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: Evidence for a metabolon
-
Meyer, F. M., J. Gerwig, E. Hammer, C. Herzberg, F. M. Commichau, U. Volker, and J. Stulke. 2011. Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon. Metab. Eng. 13: 18-27.
-
(2011)
Metab. Eng.
, vol.13
, pp. 18-27
-
-
Meyer, F.M.1
Gerwig, J.2
Hammer, E.3
Herzberg, C.4
Commichau, F.M.5
Volker, U.6
Stulke, J.7
-
35
-
-
84875935252
-
An algorithm for rapid computational construction of metabolic networks: A cholesterol biosynthesis example
-
Belič, A., D. Pompon, K. Monostory, D. Kelly, S. Kelly, and D. Rozman. 2013. An algorithm for rapid computational construction of metabolic networks: a cholesterol biosynthesis example. Comput. Biol. Med. 43: 471-480.
-
(2013)
Comput. Biol. Med.
, vol.43
, pp. 471-480
-
-
Belič, A.1
Pompon, D.2
Monostory, K.3
Kelly, D.4
Kelly, S.5
Rozman, D.6
-
36
-
-
84874612913
-
What dictates the accumulation of desmosterol in the developing brain?
-
Jansen, M., W. Wang, D. Greco, G. C. Bellenchi, U. di Porzio, A. J. Brown, and E. Ikonen. 2013. What dictates the accumulation of desmosterol in the developing brain? FASEB J. 27: 865-870.
-
(2013)
FASEB J.
, vol.27
, pp. 865-870
-
-
Jansen, M.1
Wang, W.2
Greco, D.3
Bellenchi, G.C.4
Di Porzio, U.5
Brown, A.J.6
Ikonen, E.7
-
37
-
-
84897497834
-
DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: Implications for the activities of this multifunctional enzyme
-
Zerenturk, E. J., L. J. Sharpe, and A. J. Brown. 2014. DHCR24 associates strongly with the endoplasmic reticulum beyond predicted membrane domains: implications for the activities of this multifunctional enzyme. Biosci. Rep. 34: 107-117.
-
(2014)
Biosci. Rep.
, vol.34
, pp. 107-117
-
-
Zerenturk, E.J.1
Sharpe, L.J.2
Brown, A.J.3
-
38
-
-
84923196528
-
Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum
-
Li, X., R. Roberti, and G. Blobel. 2015. Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum. Nature. 517: 104-107.
-
(2015)
Nature
, vol.517
, pp. 104-107
-
-
Li, X.1
Roberti, R.2
Blobel, G.3
|