-
1
-
-
79953746223
-
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
-
Shin, K. et al. Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 472, 110-114 (2011).
-
(2011)
Nature
, vol.472
, pp. 110-114
-
-
Shin, K.1
-
2
-
-
0022728642
-
Morphogenesis of ductal networks in the mouse prostate
-
Sugimura, Y., Cunha, G. R. &Donjacour, A. A. Morphogenesis of ductal networks in the mouse prostate. Biol. Reprod. 34, 961-971 (1986).
-
(1986)
Biol. Reprod
, vol.34
, pp. 961-971
-
-
Sugimura, Y.1
Cunha, G.R.2
Donjacour, A.A.3
-
3
-
-
0022967876
-
Morphological and histological study of castration-induced degeneration and androgen-induced regeneration in the mouse prostate
-
Sugimura, Y., Cunha, G. &Donjacour, A. Morphological and histological study of castration-induced degeneration and androgen-induced regeneration in the mouse prostate. Biol. Reprod. 34, 973-983 (1986).
-
(1986)
Biol. Reprod
, vol.34
, pp. 973-983
-
-
Sugimura, Y.1
Cunha, G.2
Donjacour, A.3
-
4
-
-
77953141037
-
Benign prostatic hyperplasia
-
Paolone, D. R. Benign prostatic hyperplasia. Clin. Geriatr. Med. 26, 223-239 (2010).
-
(2010)
Clin. Geriatr. Med
, vol.26
, pp. 223-239
-
-
Paolone, D.R.1
-
5
-
-
1542357306
-
Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis
-
Berman, D. M. et al. Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev. Biol. 267, 387-398 (2004).
-
(2004)
Dev. Biol
, vol.267
, pp. 387-398
-
-
Berman, D.M.1
-
6
-
-
33745882968
-
Functional compensation in Hedgehog signaling during mouse prostate development
-
Doles, J. et al. Functional compensation in Hedgehog signaling during mouse prostate development. Dev. Biol. 295, 13-25 (2006).
-
(2006)
Dev. Biol
, vol.295
, pp. 13-25
-
-
Doles, J.1
-
7
-
-
6044243650
-
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
-
Karhadkar, S. S. et al. Hedgehog signalling in prostate regeneration, neoplasia and metastasis. Nature 431, 707-712 (2004).
-
(2004)
Nature
, vol.431
, pp. 707-712
-
-
Karhadkar, S.S.1
-
8
-
-
84881486265
-
Differential stage-dependent regulation of prostatic epithelial morphogenesis by Hedgehog signaling
-
Yu, M. &Bushman, W. Differential stage-dependent regulation of prostatic epithelial morphogenesis by Hedgehog signaling. Dev. Biol. 380, 87-98 (2013).
-
(2013)
Dev. Biol
, vol.380
, pp. 87-98
-
-
Yu, M.1
Bushman, W.2
-
9
-
-
0344925869
-
Sonic hedgehog regulates prostatic growth and epithelial differentiation
-
Freestone, S. et al. Sonic hedgehog regulates prostatic growth and epithelial differentiation. Dev. Biol. 264, 352-362 (2003).
-
(2003)
Dev. Biol
, vol.264
, pp. 352-362
-
-
Freestone, S.1
-
10
-
-
0038381478
-
Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells
-
Wang, B-E. et al. Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells. J. Biol. Chem. 278, 18506-18513 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 18506-18513
-
-
Wang, B.-E.1
-
11
-
-
4344655390
-
Sonic hedgehog-patched Gli signaling in the developing rat prostate gland: Lobe-specific suppression by neonatal estrogens reduces ductal growth and branching
-
Pu, Y., Huang, L. &Prins, G. Sonic hedgehog-patched Gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branching. Dev. Biol. 273, 257-275 (2004).
-
(2004)
Dev. Biol
, vol.273
, pp. 257-275
-
-
Pu, Y.1
Huang, L.2
Prins, G.3
-
12
-
-
0033136040
-
Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium
-
Podlasek, C., Barnett, D., Clemens, J., Bak, P. &Bushman, W. Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium. Dev. Biol. 209, 28-39 (1999).
-
(1999)
Dev. Biol
, vol.209
, pp. 28-39
-
-
Podlasek, C.1
Barnett, D.2
Clemens, J.3
Bak, P.4
Bushman, W.5
-
13
-
-
0036385832
-
Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation
-
Lamm, M. et al. Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev. Biol. 249, 349-366 (2002).
-
(2002)
Dev. Biol
, vol.249
, pp. 349-366
-
-
Lamm, M.1
-
14
-
-
84890834389
-
Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration
-
Peng, Y-C., Levine, C. M., Zahid, S., Wilson, E. L. &Joyner, A. L. Sonic hedgehog signals to multiple prostate stromal stem cells that replenish distinct stromal subtypes during regeneration. Proc. Natl Acad. Sci. USA 110, 20611-20616 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 20611-20616
-
-
Peng, Y.-C.1
Levine, C.M.2
Zahid, S.3
Wilson, E.L.4
Joyner, A.L.5
-
15
-
-
80054995024
-
Scale: A chemical approach for fluorescence imaging and reconstruction of transparent mouse brain
-
Hama, H. et al. Scale: a chemical approach for fluorescence imaging and reconstruction of transparent mouse brain. Nat. Neurosci. 14, 1481-1488 (2011).
-
(2011)
Nat. Neurosci
, vol.14
, pp. 1481-1488
-
-
Hama, H.1
-
16
-
-
0029127339
-
HGF/SF: A potent cytokine for mammary growth, morphogenesis and development
-
Niranjan, B. et al. HGF/SF: a potent cytokine for mammary growth, morphogenesis and development. Development 121, 2897-2908 (1995).
-
(1995)
Development
, vol.121
, pp. 2897-2908
-
-
Niranjan, B.1
-
17
-
-
0028919917
-
Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells
-
Soriano, J. V., Pepper, M. S., Nakamura, T., Orci, L. &Montesano, R. Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. J. Cell Sci. 108, 413-430 (1995).
-
(1995)
J. Cell Sci
, vol.108
, pp. 413-430
-
-
Soriano, J.V.1
Pepper, M.S.2
Nakamura, T.3
Orci, L.4
Montesano, R.5
-
18
-
-
0031922793
-
Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development
-
Ohmichi, H., Koshimizu, U., Matsumoto, K. &Nakamura, T. Hepatocyte growth factor (HGF) acts as a mesenchyme-derived morphogenic factor during fetal lung development. Development 125, 1315-1324 (1998).
-
(1998)
Development
, vol.125
, pp. 1315-1324
-
-
Ohmichi, H.1
Koshimizu, U.2
Matsumoto, K.3
Nakamura, T.4
-
19
-
-
0028221326
-
Involvement of hepatocyte growth factor in kidney development
-
Santos, O. F. P. et al. Involvement of hepatocyte growth factor in kidney development. Dev. Biol. 163, 525-529 (1994).
-
(1994)
Dev. Biol
, vol.163
, pp. 525-529
-
-
Santos, O.F.P.1
-
20
-
-
77954069855
-
Isolation, cultivation and characterization of adult murine prostate stem cells
-
Lukacs, R. U., Goldstein, A. S., Lawson, D. A., Cheng, D. &Witte, O. N. Isolation, cultivation and characterization of adult murine prostate stem cells. Nat. Protoc. 5, 702-713 (2010).
-
(2010)
Nat. Protoc
, vol.5
, pp. 702-713
-
-
Lukacs, R.U.1
Goldstein, A.S.2
Lawson, D.A.3
Cheng, D.4
Witte, O.N.5
-
21
-
-
0023661693
-
Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
-
Stoker, M., Gherardi, E., Perryman, M. &Gray, J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 327, 239-242 (1987).
-
(1987)
Nature
, vol.327
, pp. 239-242
-
-
Stoker, M.1
Gherardi, E.2
Perryman, M.3
Gray, J.4
-
22
-
-
0034738979
-
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
-
Taipale, J. et al. Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine. Nature 406, 1005-1009 (2000).
-
(2000)
Nature
, vol.406
, pp. 1005-1009
-
-
Taipale, J.1
-
23
-
-
0025824738
-
Identification of a fibroblastderived epithelial morphogen as hepatocyte growth factor
-
Montesano, R., Matsumoto, K., Nakamura, T. &Orci, L. Identification of a fibroblastderived epithelial morphogen as hepatocyte growth factor. Cell 67, 901-908 (1991).
-
(1991)
Cell
, vol.67
, pp. 901-908
-
-
Montesano, R.1
Matsumoto, K.2
Nakamura, T.3
Orci, L.4
-
24
-
-
0025825990
-
Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors
-
Montesano, R., Schaller, G. &Orci, L. Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors. Cell 66, 697-711 (1991).
-
(1991)
Cell
, vol.66
, pp. 697-711
-
-
Montesano, R.1
Schaller, G.2
Orci, L.3
-
25
-
-
33846065145
-
Isolation and functional characterization of murine prostate stem cells
-
Lawson, D., Xin, L., Lukacs, R., Cheng, D. &Witte, O. Isolation and functional characterization of murine prostate stem cells. Proc. Natl Acad. Sci. USA 104, 181-186 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 181-186
-
-
Lawson, D.1
Xin, L.2
Lukacs, R.3
Cheng, D.4
Witte, O.5
-
26
-
-
58549086529
-
Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics
-
Goldstein, A. S. et al. Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics. Proc. Natl Acad. Sci. USA 105, 20882-20887 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 20882-20887
-
-
Goldstein, A.S.1
-
27
-
-
70349438989
-
A luminal epithelial stem cell that is a cell of origin for prostate cancer
-
Wang, X. et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 461, 495-500 (2009).
-
(2009)
Nature
, vol.461
, pp. 495-500
-
-
Wang, X.1
-
28
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
Huh, C. G. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc. Natl Acad. Sci. USA 101, 4477-4482 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 4477-4482
-
-
Huh, C.G.1
-
29
-
-
46849101000
-
Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2- yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1 H-pyrazole-4-carboxamide (AMG 458)
-
Liu, L. et al. Discovery of a potent, selective, and orally bioavailable c-Met inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2- yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1 H-pyrazole-4-carboxamide (AMG 458). J. Med. Chem. 51, 3688-3691 (2008).
-
(2008)
J. Med. Chem
, vol.51
, pp. 3688-3691
-
-
Liu, L.1
-
30
-
-
0033583035
-
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3
-
Dai, P. et al. Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J. Biol. Chem. 274, 8143-8152 (1999).
-
(1999)
J. Biol. Chem
, vol.274
, pp. 8143-8152
-
-
Dai, P.1
-
31
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B. P., Burge, C. B. &Bartel, D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005).
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
32
-
-
70449372292
-
Accurate microRNA target prediction correlates with protein repression levels
-
Maragkakis, M. et al. Accurate microRNA target prediction correlates with protein repression levels. BMC Bioinformatics 10, 295-304 (2009).
-
(2009)
BMC Bioinformatics
, vol.10
, pp. 295-304
-
-
Maragkakis, M.1
-
33
-
-
67650747402
-
DIANA-microT web server: Elucidating microRNA functions through target prediction
-
Maragkakis, M. et al. DIANA-microT web server: elucidating microRNA functions through target prediction. Nucleic Acids Res. 37, W273-W276 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, pp. W273-W276
-
-
Maragkakis, M.1
-
34
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D. P. MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233 (2009).
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel D. ., P.1
-
35
-
-
4644328190
-
Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities
-
Harfe, B. et al. Evidence for an expansion-based temporal Shh gradient in specifying vertebrate digit identities. Cell 118, 517-528 (2004).
-
(2004)
Cell
, vol.118
, pp. 517-528
-
-
Harfe, B.1
-
36
-
-
0025296064
-
Pathology of benign prostatic hyperplasia. Insight into etiology
-
McNeal, J. E. Pathology of benign prostatic hyperplasia. Insight into etiology. Urol. Clin. North Am. 17, 477-486 (1990).
-
(1990)
Urol. Clin. North Am
, vol.17
, pp. 477-486
-
-
McNeal, J.E.1
-
37
-
-
0018150495
-
Origin and evolution of benign prostatic enlargement
-
McNeal, J. E. Origin and evolution of benign prostatic enlargement. Invest. Urol. 15, 340-345 (1978).
-
(1978)
Invest. Urol
, vol.15
, pp. 340-345
-
-
McNeal J. ., E.1
-
38
-
-
0025284127
-
Evolving patterns of tissue composition in benign prostatic hyperplasia as a function of specimen size
-
Price, H., McNeal, J. E. &Stamey, T. A. Evolving patterns of tissue composition in benign prostatic hyperplasia as a function of specimen size. Hum. Pathol. 21, 578-585 (1990).
-
(1990)
Hum. Pathol
, vol.21
, pp. 578-585
-
-
Price, H.1
McNeal, J.E.2
Stamey, T.A.3
-
39
-
-
5444249242
-
Molecular and cellular pathogenesis of benign prostatic hyperplasia
-
Lee, K. L. &Peehl, D. M. Molecular and cellular pathogenesis of benign prostatic hyperplasia. J. Urol. 172, 1784-1791 (2004).
-
(2004)
J. Urol
, vol.172
, pp. 1784-1791
-
-
Lee, K.L.1
Peehl, D.M.2
-
40
-
-
14844301664
-
Benign prostatic hyperplasia: Agerelated tissue-remodeling
-
Untergasser, G., Madersbacher, S. &Berger, P. Benign prostatic hyperplasia: agerelated tissue-remodeling. Exp. Gerontol. 40, 121-128 (2005).
-
(2005)
Exp. Gerontol
, vol.40
, pp. 121-128
-
-
Untergasser, G.1
Madersbacher, S.2
Berger, P.3
-
41
-
-
3843089435
-
Hedgehog signaling promotes prostate xenograft tumor growth
-
Fan, L. et al. Hedgehog signaling promotes prostate xenograft tumor growth. Endocrinology 145, 3961-3970 (2004).
-
(2004)
Endocrinology
, vol.145
, pp. 3961-3970
-
-
Fan, L.1
-
42
-
-
0028979240
-
C-met proto-oncogene expression in benign and malignant human prostate tissues
-
Pisters, L. L. et al. c-met proto-oncogene expression in benign and malignant human prostate tissues. J. Urol. 154, 293-298 (1995).
-
(1995)
J. Urol
, vol.154
, pp. 293-298
-
-
Pisters, L.L.1
-
43
-
-
0034490943
-
Hepatocyte growth factor secreted by prostate-derived stromal cells stimulates growth of androgen-independent human prostatic carcinoma cells
-
Nakashiro, K., Okamoto, M., Hayashi, Y. &Oyasu, R. Hepatocyte growth factor secreted by prostate-derived stromal cells stimulates growth of androgen-independent human prostatic carcinoma cells. Am. J. Pathol. 157, 795-803 (2000).
-
(2000)
Am. J. Pathol
, vol.157
, pp. 795-803
-
-
Nakashiro, K.1
Okamoto, M.2
Hayashi, Y.3
Oyasu, R.4
-
44
-
-
0036801765
-
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
-
Bai, C., Auerbach, W., Lee, J., Stephen, D. &Joyner, A. Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development 129, 4753-4761 (2002).
-
(2002)
Development
, vol.129
, pp. 4753-4761
-
-
Bai, C.1
Auerbach, W.2
Lee, J.3
Stephen, D.4
Joyner, A.5
-
45
-
-
4043122029
-
Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning
-
Ahn, S. &Joyner, A. Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning. Cell 118, 505-516 (2004).
-
(2004)
Cell
, vol.118
, pp. 505-516
-
-
Ahn, S.1
Joyner, A.2
-
46
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
Srinivas, S. et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev. Biol. 1, 4 (2001).
-
(2001)
BMC Dev. Biol
, vol.1
, pp. 4
-
-
Srinivas, S.1
-
47
-
-
35548932872
-
A global doublefluorescent Cre reporter mouse
-
Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L. &Luo, L. A global doublefluorescent Cre reporter mouse. Genesis 45, 593-605 (2007).
-
(2007)
Genesis
, vol.45
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, L.4
Luo, L.5
-
48
-
-
0035691559
-
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation
-
Long, F., Zhang, X. M., Karp, S., Yang, Y. &McMahon, A. P. Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development 128, 5099-5108 (2001).
-
(2001)
Development
, vol.128
, pp. 5099-5108
-
-
Long, F.1
Zhang, X.M.2
Karp, S.3
Yang, Y.4
McMahon, A.P.5
-
49
-
-
34547589578
-
DAVID Bioinformatics Resources: Expanded annotation database and novel algorithms to better extract biology from large gene lists
-
Huang, D. W. et al. DAVID Bioinformatics Resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Res. 35, W169-W175 (2007).
-
(2007)
Nucleic Acids Res
, vol.35
, pp. W169-W175
-
-
Huang, D.W.1
-
50
-
-
69949084378
-
GDC-0449-A potent inhibitor of the hedgehog pathway
-
Robarge, K. et al. GDC-0449-A potent inhibitor of the hedgehog pathway. Bioorg. Med. Chem. Lett. 19, 5576-5581 (2009).
-
(2009)
Bioorg. Med. Chem. Lett
, vol.19
, pp. 5576-5581
-
-
Robarge, K.1
|