Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening

Circulation Research

Volumn 116, Issue 3, 2015, Pages 425-436

  Van Aelst, Lucas N L ^a,b   Voss, Sandra ^c   Carai, Paolo ^a,d   Van Leeuwen, Rick ^d   Vanhoutte, Davy ^e   Sanders Van Wijk, Sandra ^d   Eurlings, Luc ^d   Swinnen, Melissa ^b   Verheyen, Fons K ^d   Verbeken, Eric ^b   Nef, Holger ^c   Troidl, Christian ^c   Cook, Stuart A ^f,g,h   Brunner La Rocca, Hans Peter ^d,i   Möllmann, Helge ^c   Papageorgiou, Anna Pia ^a,d   Heymans, Stephane ^a,d,j  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^c KERCKHOFF HEART CENTER   (Germany)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^f NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^g DEPARTMENT OF CARDIOLOGY   (Singapore)

^h DUKE NUS MEDICAL SCHOOL   (Singapore)

ⁱ UNIVERSITY HOSPITAL BASEL   (Switzerland)

^j ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

more..

Author keywords

Cardiac remodeling; Fibrosis; Heart failure; Heart rupture; Myocardial infarction; Ventricular

Indexed keywords

COLLAGEN; OSTEOGLYCIN; PROTEOGLYCAN; UNCLASSIFIED DRUG; LYMPHOTOXIN; OGN PROTEIN, HUMAN; OGN PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLLAGEN FIBER; CONTROLLED STUDY; ELECTRON MICROSCOPY; HEART DILATATION; HEART FAILURE; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE VOLUME; HEART RUPTURE; HUMAN; HUMAN TISSUE; ISCHEMIC HEART DISEASE; MORTALITY; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SURVIVAL; ANIMAL; BLOOD; C57BL MOUSE; CARDIOMEGALY; CYTOLOGY; FIBROBLAST; GENETICS; HEART MUSCLE CELL; HEART VENTRICLE REMODELING; LEWIS RAT; METABOLISM; PATHOLOGY; PHYSIOLOGY; SCAR;

ANIMALS; CARDIOMEGALY; CICATRIX; COLLAGEN; FIBROBLASTS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOTOXIN-ALPHA; MICE; MICE, INBRED C57BL; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RATS; RATS, INBRED LEW; VENTRICULAR REMODELING;

EID: 84927173044     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.304599     Document Type: Article

References (33)

1. Steg PG, James SK, Atar D, Badano LP, Blomstrom-Lundqvist C, Borger MA, Di Mario C, Dickstein K, Ducrocq G, Fernandez-Aviles F, Gershlick AH, Giannuzzi P, Halvorsen S, Huber K, Juni P, Kastrati A, Knuuti J, Lenzen MJ, Mahaffey KW, Valgimigli M, van 't Hof A, Widimsky P, Zahger D. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012;33:2569-619.
2. Dickstein K, Cohen-Solal A, Filippatos G, McMurray JJ, Ponikowski P, Poole-Wilson PA, Stromberg A, van Veldhuisen DJ, Atar D, Hoes AW, Keren A, Mebazaa A, Nieminen M, Priori SG, Swedberg K. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008: the Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM). Eur Heart J. 2008;29:2388-442.
3. Herbertson LH, Manning KB, Reddy V, Fontaine AA, Tarbell JM, Deutsch S. The effect of dissolved carbon dioxide on cavitation intensity in mechanical heart valves. J Heart Valve Dis. 2005;14:835-842.
4. Komajda M, Hanon O, Hochadel M, Lopez-Sendon JL, Follath F, Ponikowski P, Harjola VP, Drexler H, Dickstein K, Tavazzi L, Nieminen M. Contemporary management of octogenarians hospitalized for heart failure in Europe: Euro Heart Failure Survey II. Eur Heart J. 2009;30:478-486. Doi:10.1093/eurheartj/ehn539.
5. van der Laan AM, Nahrendorf M, Piek JJ. Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response. Heart. 2012;98:1384-1390. Doi:10.1136/heartjnl-2012-301623.
6. Heymans S, Luttun A, Nuyens D, et al. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure. Nat Med. 1999;5:1135-1142. Doi:10.1038/13459.
7. Bentz H, Chang RJ, Thompson AY, Glaser CB, Rosen DM. Amino acid sequence of bovine osteoinductive factor. J Biol Chem. 1990;265:5024-5029.
8. Williamson RE, Darrow KN, Giersch AB, Resendes BL, Huang M, Conrad GW, Chen ZY, Liberman MC, Morton CC, Tasheva ES. Expression studies of osteoglycin/mimecan (OGN) in the cochlea and auditory phenotype of Ogn-deficient mice. Hear Res. 2008;237:57-65. Doi:10.1016/j.heares.2007.12.006.
9. Romero R, Kusanovic JP, Gotsch F, et al. Isobaric labeling and tandem mass spectrometry: a novel approach for profiling and quantifying proteins differentially expressed in amniotic fluid in preterm labor with and without intra-amniotic infection/inflammation. J Matern Fetal Neonatal Med. 2010;23:261-280. Doi:10.3109/14767050903067386.
10. Hu SM, Li F, Yu HM, Li RY, Ma QY, Ye TJ, Lu ZY, Chen JL, Song HD. The mimecan gene expressed in human pituitary and regulated by pituitary transcription factor-1 as a marker for diagnosing pituitary tumors. J Clin Endocrinol Metab. 2005;90:6657-6664. Doi:10.1210/jc.2005-0322.
11. Tasheva ES, Ke A, Deng Y, Jun C, Takemoto LJ, Koester A, Conrad GW. Differentially expressed genes in the lens of mimecan-null mice. Mol Vis. 2004;10:403-416.
12. Tasheva ES, Koester A, Paulsen AQ, Garrett AS, Boyle DL, Davidson HJ, Song M, Fox N, Conrad GW. Mimecan/osteoglycin-deficient mice have collagen fibril abnormalities. Mol Vis. 2002;8:407-415.
13. Petretto E, Sarwar R, Grieve I, et al. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet. 2008;40:546-552. Doi:10.1038/ng.134.
14. Iozzo RV. The biology of the small leucine-rich proteoglycans. Functional network of interactive proteins. J Biol Chem. 1999;274:18843-18846.
15. Lutgens E, Daemen MJ, de Muinck ED, Debets J, Leenders P, Smits JF. Chronic myocardial infarction in the mouse: cardiac structural and functional changes. Cardiovasc Res. 1999;41:586-593.
16. Eurlings LW, Sanders-van Wijk S, van Kimmenade R, Osinski A, van Helmond L, Vallinga M, Crijns HJ, van Dieijen-Visser MP, Brunner-La Rocca HP, Pinto YM. Multimarker strategy for short-term risk assessment in patients with dyspnea in the emergency department: the MARKED (Multi mARKer Emergency Dyspnea)-risk score. J Am Coll Cardiol. 2012;60:1668-1677. Doi:10.1016/j.jacc.2012.06.040.
17. Pfisterer M, Buser P, Rickli H, et al; TIME-CHF Investigators. BNPguided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME-CHF) randomized trial. JAMA. 2009;301:383-392. Doi:10.1001/jama.2009.2.
18. Stypmann J, Engelen MA, Troatz C, Rothenburger M, Eckardt L, Tiemann K. Echocardiographic assessment of global left ventricular function in mice. Lab Anim. 2009;43:127-137. Doi:10.1258/la.2007.06001e.
19. Schellings MW, Vanhoutte D, Swinnen M, Cleutjens JP, Debets J, van Leeuwen RE, d'Hooge J, Van de Werf F, Carmeliet P, Pinto YM, Sage EH, Heymans S. Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. J Exp Med. 2009;206:113-123. Doi:10.1084/jem.20081244.
20. Kleiner DE, Stetler-Stevenson WG. Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem. 1994;218:325-329.
21. Swinnen M, Vanhoutte D, Van Almen GC, et al. Absence of thrombospondin-2 causes age-related dilated cardiomyopathy. Circulation. 2009;120:1585-1597. Doi:10.1161/CIRCULATIONAHA.109.863266.
22. Ruberg FL, Kissinger KV, Manning WJ. Images in cardiovascular medicine. Diaphragmatic motion during Cheyne-Stokes respiration by navigator magnetic resonance imaging. Circulation. 2005;112:e132. Doi:10.1161/CIRCULATIONAHA.104.508671.
23. Chen W, Frangogiannis NG. Fibroblasts in post-infarction inflammation and cardiac repair. Biochim Biophys Acta. 2013;1833:945-953. Doi:10.1016/j.bbamcr.2012.08.023.
24. Fang L, Gao XM, Moore XL, Kiriazis H, Su Y, Ming Z, Lim YL, Dart AM, Du XJ. Differences in inflammation, MMP activation and collagen damage account for gender difference in murine cardiac rupture following myocardial infarction. J Mol Cell Cardiol. 2007;43:535-544. Doi:10.1016/j.yjmcc.2007.06.011.
25. Chen Q, Williams R, Healy CL, Wright CD, Wu SC, O'Connell TD. An association between gene expression and better survival in female mice following myocardial infarction. J Mol Cell Cardiol. 2010;49:801-811. Doi:10.1016/j.yjmcc.2010.08.002.
26. Bi Y, Ehirchiou D, Kilts TM, Inkson CA, Embree MC, Sonoyama W, Li L, Leet AI, Seo BM, Zhang L, Shi S, Young MF. Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med. 2007;13:1219-1227. Doi:10.1038/nm1630.
27. Myllyharju J, Kivirikko KI. Collagens and collagen-related diseases. Ann Med. 2001;33:7-21.
28. Westermann D, Mersmann J, Melchior A, et al. Biglycan is required for adaptive remodeling after myocardial infarction. Circulation. 2008;117:1269-1276. Doi:10.1161/CIRCULATIONAHA.107.714147.
29. Lewis PN, Pinali C, Young RD, Meek KM, Quantock AJ, Knupp C. Structural interactions between collagen and proteoglycans are elucidated by three-dimensional electron tomography of bovine cornea. Structure. 2010;18:239-245. Doi:10.1016/j.str.2009.11.013.
30. Scott JE, Haigh M. Identification of specific binding sites for keratan sulphate proteoglycans and chondroitin-dermatan sulphate proteoglycans on collagen fibrils in cornea by the use of cupromeronic blue in 'critical-electrolyte-concentration' techniques. Biochem J. 1988;253:607-610.
31. Sweeney SM, Orgel JP, Fertala A, McAuliffe JD, Turner KR, Di Lullo GA, Chen S, Antipova O, Perumal S, Ala-Kokko L, Forlino A, Cabral WA, Barnes AM, Marini JC, San Antonio JD. Candidate cell and matrix interaction domains on the collagen fibril, the predominant protein of vertebrates. J Biol Chem. 2008;283:21187-21197. Doi:10.1074/jbc.M709319200.
32. Burchfield JS, Xie M, Hill JA. Pathological ventricular remodeling: mechanisms: part 1 of 2. Circulation. 2013;128:388-400. Doi:10.1161/ CIRCULATIONAHA.113.001878.
33. McKie PM, Burnett JC Jr. B-type natriuretic peptide as a biomarker beyond heart failure: speculations and opportunities. Mayo Clin Proc. 2005;80:1029-1036. Doi:10.4065/80.8.1029.