-
1
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Jänne PA, Lee JC, et al: EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science 304:1497-1500, 2004
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Jänne, P.A.2
Lee, J.C.3
-
2
-
-
78049429691
-
Crizotinib: Latest champion in the cancer wars?
-
Hallberg B, Palmer RH: Crizotinib: Latest champion in the cancer wars? N Engl J Med 363:1760-1762, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 1760-1762
-
-
Hallberg, B.1
Palmer, R.H.2
-
4
-
-
84904607389
-
Biomarkers that currently affect clinical practice in lung cancer: EGFR, ALK, MET, ROS-1, and KRAS
-
Korpanty GJ, Graham DM, Vincent MD, et al: Biomarkers that currently affect clinical practice in lung cancer: EGFR, ALK, MET, ROS-1, and KRAS. Front Oncol 4:204, 2014
-
(2014)
Front Oncol
, vol.4
, pp. 204
-
-
Korpanty, G.J.1
Graham, D.M.2
Vincent, M.D.3
-
6
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, et al: Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med 363:809-819, 2010
-
(2010)
N Engl J Med
, vol.363
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
-
7
-
-
79959293462
-
BRAF mutations in hairy-cell leukemia
-
Tiacci E, Trifonov V, Schiavoni G, et al: BRAF mutations in hairy-cell leukemia. N Engl J Med 364:2305-2315, 2011
-
(2011)
N Engl J Med
, vol.364
, pp. 2305-2315
-
-
Tiacci, E.1
Trifonov, V.2
Schiavoni, G.3
-
8
-
-
84863230465
-
Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR
-
Prahallad A, Sun C, Huang S, et al: Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR. Nature 483:100-103, 2012
-
(2012)
Nature
, vol.483
, pp. 100-103
-
-
Prahallad, A.1
Sun, C.2
Huang, S.3
-
9
-
-
80053014471
-
Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations
-
Marchetti A, Felicioni L, Malatesta S, et al: Clinical features and outcome of patients with non-small-cell lung cancer harboring BRAF mutations. J Clin Oncol 29:3574-3579, 2011
-
(2011)
J Clin Oncol
, vol.29
, pp. 3574-3579
-
-
Marchetti, A.1
Felicioni, L.2
Malatesta, S.3
-
10
-
-
84920593838
-
Association between BRAF V600E mutation and recurrence of papillary thyroid cancer
-
Xing M, Alzahrani AS, Carson KA, et al: Association between BRAF V600E mutation and recurrence of papillary thyroid cancer. J Clin Oncol 33:42-50, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 42-50
-
-
Xing, M.1
Alzahrani, A.S.2
Carson, K.A.3
-
11
-
-
84927788699
-
BRAF alterations in brain tumours: Molecular pathology and therapeutic opportunities
-
Berghoff AS, Preusser M: BRAF alterations in brain tumours: Molecular pathology and therapeutic opportunities. Curr Opin Neurol 27:689-696, 2014
-
(2014)
Curr Opin Neurol
, vol.27
, pp. 689-696
-
-
Berghoff, A.S.1
Preusser, M.2
-
12
-
-
33644845421
-
First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: A phase II study
-
Niho S, Kubota K, Goto K, et al: First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: A phase II study. J Clin Oncol 24:64-69, 2006
-
(2006)
J Clin Oncol
, vol.24
, pp. 64-69
-
-
Niho, S.1
Kubota, K.2
Goto, K.3
-
13
-
-
52049096854
-
Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study
-
Crinò L, Cappuzzo F, Zatloukal P, et al: Gefitinib versus vinorelbine in chemotherapy-naive elderly patients with advanced non-small-cell lung cancer (INVITE): A randomized, phase II study. J Clin Oncol 26:4253-4260, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 4253-4260
-
-
Crinò, L.1
Cappuzzo, F.2
Zatloukal, P.3
-
14
-
-
84899680978
-
Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib
-
Wagle N, Grabiner BC, Van Allen EM, et al: Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib. Cancer Discov 4:546-553, 2014
-
(2014)
Cancer Discov
, vol.4
, pp. 546-553
-
-
Wagle, N.1
Grabiner, B.C.2
Van Allen, E.M.3
-
15
-
-
84907863603
-
Response and acquired resistance to everolimus in anaplastic thyroid cancer
-
Wagle N, Grabiner BC, Van Allen EM, et al: Response and acquired resistance to everolimus in anaplastic thyroid cancer. N Engl J Med 371:1426-1433, 2014
-
(2014)
N Engl J Med
, vol.371
, pp. 1426-1433
-
-
Wagle, N.1
Grabiner, B.C.2
Van Allen, E.M.3
-
16
-
-
84927164071
-
Molecular profiling and targeted therapy for advanced thoracic malignancies: A biomarker-derived, multiarm, multihistology phase II basket trial
-
Lopez-Chavez A, Thomas A, Rajan A, et al: Molecular profiling and targeted therapy for advanced thoracic malignancies: A biomarker-derived, multiarm, multihistology phase II basket trial. J Clin Oncol 33:1000-1007, 2015
-
(2015)
J Clin Oncol
, vol.33
, pp. 1000-1007
-
-
Lopez-Chavez, A.1
Thomas, A.2
Rajan, A.3
-
18
-
-
84871720411
-
Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: A randomised, multicentre, placebo-controlled, phase 2 study
-
Jänne PA, Shaw AT, Pereira JR, et al: Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: A randomised, multicentre, placebo-controlled, phase 2 study. Lancet Oncol 14:38-47, 2013
-
(2013)
Lancet Oncol
, vol.14
, pp. 38-47
-
-
Jänne, P.A.1
Shaw, A.T.2
Pereira, J.R.3
-
19
-
-
84862777541
-
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response
-
Chen Z, Cheng K, Walton Z, et al: A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response. Nature 483:613-617, 2012
-
(2012)
Nature
, vol.483
, pp. 613-617
-
-
Chen, Z.1
Cheng, K.2
Walton, Z.3
|