Orthostatic Hypotension in Parkinson Disease: How Much You Fall or How Low You Go?

Movement Disorders

Volumn 30, Issue 5, 2015, Pages 639-645

  Palma, Jose Alberto ^a   Gomez Esteban, Juan Carlos ^b   Norcliffe Kaufmann, Lucy ^a   Martinez, Jose ^a   Tijero, Beatriz ^b   Berganzo, Koldo ^b   Kaufmann, Horacio ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HOSPITAL DE CRUCES   (Spain)

Author keywords

Autonomic failure; Consensus criteria; Dysautonomia; Mean blood pressure; Standing blood pressure; Supine hypertension

Indexed keywords

ANTIHYPERTENSIVE AGENT; FLUDROCORTISONE; LEVODOPA; MIDODRINE; ANTIPARKINSON AGENT;

ADULT; AGED; ARTICLE; BLOOD PRESSURE; FALLING; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; ORTHOSTATIC HYPOTENSION; PARKINSON DISEASE; PERFUSION; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; QUESTIONNAIRE; AGE; COMPLICATION; EUROPE; HYPOTENSION, ORTHOSTATIC; MIDDLE AGED; PHYSIOLOGY; PROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; UNITED STATES;

AGE FACTORS; AGED; ANTIPARKINSON AGENTS; BLOOD PRESSURE; EUROPE; FEMALE; HUMANS; HYPOTENSION, ORTHOSTATIC; LEVODOPA; MALE; MIDDLE AGED; PARKINSON DISEASE; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; SURVEYS AND QUESTIONNAIRES; UNITED STATES;

EID: 84926998102     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.26079     Document Type: Article

References (37)

1. Velseboer DC, de Haan RJ, Wieling W, Goldstein DS, de Bie RM. Prevalence of orthostatic hypotension in Parkinson's disease: a systematic review and meta-analysis. Parkinsonism Relat Disord 2011;17:724-729.
2. Wieling W, Thijs RD, van Dijk N, Wilde AA, Benditt DG, van Dijk JG. Symptoms and signs of syncope: a review of the link between physiology and clinical clues. Brain 2009;132:2630-2642.
3. Masaki KH, Schatz IJ, Burchfiel CM, et al. Orthostatic hypotension predicts mortality in elderly men: the Honolulu Heart Program. Circulation 1998;98:2290-2295.
4. Mtinangi BL, Hainsworth R. Effects of moderate exercise training on plasma volume, baroreceptor sensitivity and orthostatic tolerance in healthy subjects. Exp Physiol 1999;84:121-130.
5. Bonnin P, Ben Driss A, Benessiano J, Maillet A, Pavy le Traon A, Levy BI. Enhanced flow-dependent vasodilatation after bed rest, a possible mechanism for orthostatic intolerance in humans. Eur J Appl Physiol 2001;85:420-426.
6. Izcovich A, González Malla C, Manzotti M, Catalano HN, Guyatt G. Midodrine for orthostatic hypotension and recurrent reflex syncope: a systematic review. Neurology 2014;83:1170-1177.
7. Kaufmann H, Freeman R, Biaggioni I, et al. Droxidopa for neurogenic orthostatic hypotension: a randomized, placebo-controlled, phase 3 trial. Neurology 2014;83:328-335.
8. Jankovic J, Gilden JL, Hiner BC, et al. Neurogenic orthostatic hypotension: a double-blind, placebo-controlled study with midodrine. Am J Med 1993;95:38-48.
9. Hohler AD, Amariei DE, Katz DI, et al. Treating orthostatic hypotension in patients with Parkinson's disease and atypical Parkinsonism improves function. J Parkinsons Dis 2012;2:235-240.
10. Goldstein DS, Holmes CS, Dendi R, Bruce SR, Li ST. Orthostatic hypotension from sympathetic denervation in Parkinson's disease. Neurology 2002;58:1247-1255.
11. Kaufmann H, Biaggioni I. Autonomic failure in neurodegenerative disorders. Semin Neurol 2003;23:351-363.
12. Low PA, Gilden JL, Freeman R, Sheng KN, McElligott MA. Efficacy of midodrine vs placebo in neurogenic orthostatic hypotension. A randomized, double-blind multicenter study. Midodrine Study Group. JAMA 1997;277:1046-1051.
13. Mazza A, Ravenni R, Antonini A, Casiglia E, Rubello D, Pauletto P. Arterial hypertension, a tricky side of Parkinson's disease: physiopathology and therapeutic features. Neurol Sci 2013;34:621-627.
14. Berganzo K, Diez-Arrola B, Tijero B, et al. Nocturnal hypertension and dysautonomia in patients with Parkinson's disease: are they related? J Neurol 2013;260:1752-1756.
15. Kaufmann H. Consensus statement on the definition of orthostatic hypotension, pure autonomic failure and multiple system atrophy. Clin Auton Res 1996;6:125-126.
16. Freeman R, Wieling W, Axelrod FB, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 2011;21:69-72.
17. Leu-Semenescu S, Roze E, Vidailhet M, et al. Myoclonus or tremor in orthostatism: an under-recognized cause of unsteadiness in Parkinson's disease. Mov Disord 2007;22:2063-2069.
18. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992;55:181-184.
19. Tomlinson CL, Stowe R, Patel S, Rick C, Gray R, Clarke CE. Systematic review of levodopa dose equivalency reporting in Parkinson's disease. Mov Disord 2010;25:2649-2653.
20. Kaufmann H, Malamut R, Norcliffe-Kaufmann L, Rosa K, Freeman R. The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale. Clin Auton Res 2012;22:79-90.
21. Pickering TG, Hall JE, Appel LJ, et al. Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension 2005;45:142-161.
22. Bewick V, Cheek L, Ball J. Statistics review 13: receiver operating characteristic curves. Crit Care 2004;8:508-512.
23. Ha AD, Brown CH, York MK, Jankovic J. The prevalence of symptomatic orthostatic hypotension in patients with Parkinson's disease and atypical parkinsonism. Parkinsonism Relat Disord 2011;17:625-628.
24. Hainsworth R. Pathophysiology of syncope. Clin Auton Res 2004;14(Suppl 1):18-24.
25. Szewczyk-Krolikowski K, Tomlinson P, Nithi K, et al. The influence of age and gender on motor and non-motor features of early Parkinson's disease: Initial findings from the Oxford Parkinson Disease Center (OPDC) discovery cohort. Parkinsonism Relat Disord 2014;20:99-105.
26. Arbogast SD, Alshekhlee A, Hussain Z, McNeeley K, Chelimsky TC. Hypotension unawareness in profound orthostatic hypotension. Am J Med 2009;122:574-580.
27. Jamnadas-Khoda J, Koshy S, Mathias CJ, Muthane UB, Ragothaman M, Dodaballapur SK. Are current recommendations to diagnose orthostatic hypotension in Parkinson's disease satisfactory? Mov Disord 2009;24:1747-1751.
28. Goldstein DS, Pechnik S, Holmes C, Eldadah B, Sharabi Y. Association between supine hypertension and orthostatic hypotension in autonomic failure. Hypertension 2003;42:136-142.
29. Niehaus L, Bockeler GC, Kupsch A, Meyer BU. Normal cerebral hemodynamic response to orthostasis in Parkinson's disease. Parkinsonism Relat Disord 2002;8:255-259.
30. Horowitz DR, Kaufmann H. Autoregulatory cerebral vasodilation occurs during orthostatic hypotension in patients with primary autonomic failure. Clin Auton Res 2001;11:363-367.
31. Henry JP, Gauer OH, Kety SS, Kramer K. Factors maintaining cerebral circulation during gravitational stress. J Clin Invest 1951;30:292-300.
32. Norcliffe-Kaufmann L, Kaufmann H. Is ambulatory blood pressure monitoring useful in patients with chronic autonomic failure? Clin Auton Res 2014;24:189-192.
33. Calne DB, Brennan J, Spiers AS, Stern GM. Hypotension caused by L-dopa. Br Med J 1970;1:474-475.
34. Bouhaddi M, Vuillier F, Fortrat JO, et al. Impaired cardiovascular autonomic control in newly and long-term-treated patients with Parkinson's disease: involvement of L-dopa therapy. Auton Neurosci 2004;116:30-38.
35. Wolf JP, Bouhaddi M, Louisy F, et al. Side-effects of L-dopa on venous tone in Parkinson's disease: a leg-weighing assessment. Clin Sci (Lond) 2006;110:369-377.
36. Gibbons CH, Freeman R. Delayed orthostatic hypotension: a frequent cause of orthostatic intolerance. Neurology 2006;67:28-32.
37. Freidenberg DL, Shaffer LE, Macalester S, Fannin EA. Orthostatic hypotension in patients with dementia: clinical features and response to treatment. Cogn Behav Neurol 2013;26:105-120.