Propionibacterium acnes in shoulder surgery: True infection, contamination, or commensal of the deep tissue?

Journal of Shoulder and Elbow Surgery

Volumn 23, Issue 12, 2014, Pages 1763-1771

  Hudek, Robert ^a   Sommer, Frank ^b   Kerwat, Martina ^b   Abdelkawi, Ayman F ^a   Loos, Franziska ^a   Gohlke, Frank ^a  

^a Rhon Klinikum AG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Anterolateral approach; Commensal; Contaminant; Deltopectoral approach; Infection; Propionibacterium acnes; Shoulder

Indexed keywords

SULTAMICILLIN;

ADULT; AGED; ARTICLE; BACTERIAL GROWTH; BACTERIAL INFECTION; BACTERIUM CONTAMINATION; COMMENSAL; COMMENSAL PROPIONIBACTERIUM ACNES; COMPARATIVE STUDY; FEMALE; GENDER; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROPIONIBACTERIUM ACNES; SEX DIFFERENCE; SHOULDER SURGERY; SOFT TISSUE INFECTION; SURGICAL TECHNIQUE; ADOLESCENT; GRAM POSITIVE INFECTION; INTRAOPERATIVE PERIOD; MICROBIOLOGY; MIDDLE AGED; SHOULDER; SKIN; SURGERY; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; GRAM-POSITIVE BACTERIAL INFECTIONS; HUMANS; INTRAOPERATIVE PERIOD; MALE; MIDDLE AGED; PROPIONIBACTERIUM ACNES; SHOULDER; SHOULDER JOINT; SKIN; YOUNG ADULT;

EID: 84926682409     PISSN: 10582746     EISSN: 15326500     Source Type: Journal    
DOI: 10.1016/j.jse.2014.05.024     Document Type: Article

References (54)

1. Achermann Y., Sahin F., Schwyzer H.K., Kolling C., Wust J., Vogt M. Characteristics and outcome of 16 periprosthetic shoulder joint infections. Infection 2013, 41:613-620. 10.1007/s15010-012-0360-4.
2. Alexeyev O.A., Marklund I., Shannon B., Golovleva I., Olsson J., Andersson C., et al. Direct visualization of Propionibacterium acnes in prostate tissue by multicolor fluorescent in situ hybridization assay. J Clin Microbiol 2007, 45:3721-3728. 10.1128/JCM.01543-07.
3. Athwal G.S., Sperling J.W., Rispoli D.M., Cofield R.H. Deep infection after rotator cuff repair. J Shoulder Elbow Surg 2007, 16:306-311. 10.1016/j.jse.2006.05.013.
4. Brook I., Frazier E.H. Infections caused by Propionibacterium species. Rev Infect Dis 1991, 13:819-822.
5. Bruggemann H., Henne A., Hoster F., Liesegang H., Wiezer A., Strittmatter A., et al. The complete genome sequence of Propionibacterium acnes, a commensal of human skin. Science 2004, 305:671-673. 10.1126/science.1100330.
6. Bruggemann H., Lomholt H.B., Kilian M. The flexible gene pool of Propionibacterium acnes. Mob Genet Elements 2012, 2:145-148. 10.4161/mge.21204.
7. Bruggemann H., Lomholt H.B., Tettelin H., Kilian M. CRISPR/cas loci of type II Propionibacterium acnes confer immunity against acquisition of mobile elements present in type I P. acnes. PLoS One 2012, 7:e34171. 10.1371/journal.pone.0034171.
8. Bruggemann H., Lood R. Bacteriophages infecting Propionibacterium acnes. Biomed Res Int 2013, 2013:705741. 10.1155/2013/705741.
9. Brzuszkiewicz E., Weiner J., Wollherr A., Thurmer A., Hupeden J., Lomholt H.B., et al. Comparative genomics and transcriptomics of Propionibacterium acnes. PLoS One 2011, 6:e21581. 10.1371/journal.pone.0021581.
10. Chen F., Wang K., Stewart J., Belas R. Induction of multiple prophages from a marine bacterium: a genomic approach. Appl Environ Microbiol 2006, 72:4995-5001. 10.1128/AEM.00056-06.
11. Chiu K.Y., Lau S.K., Fung B., Ng K.H., Chow S.P. Plastic adhesive drapes and wound infection after hip fracture surgery. Aust N Z J Surg 1993, 63:798-801.
12. Coenye T., Peeters E., Nelis H.J. Biofilm formation by Propionibacterium acnes is associated with increased resistance to antimicrobial agents and increased production of putative virulence factors. Res Microbiol 2007, 158:386-392. 10.1016/j.resmic.2007.02.001.
13. Cohen R.J., Shannon B.A., McNeal J.E., Shannon T., Garrett K.L. Propionibacterium acnes associated with inflammation in radical prostatectomy specimens: a possible link to cancer evolution?. J Urol 2005, 173:1969-1974. 10.1097/01.ju.0000158161.15277.78.
14. Dodson C.C., Craig E.V., Cordasco F.A., Dines D.M., Dines J.S., Dicarlo E., et al. Propionibacterium acnes infection after shoulder arthroplasty: a diagnostic challenge. J Shoulder Elbow Surg 2010, 19:303-307. 10.1016/j.jse.2009.07.065.
15. Dramis A., Aldlyami E., Grimer R.J., Dunlop D.J., O'Connell N., Elliott T. What is the significance of a positive Propionibacterium acnes culture around a joint replacement?. Int Orthop 2009, 33:829-833. 10.1007/s00264-008-0534-y.
16. Falk-Brynhildsen K., Soderquist B., Friberg O., Nilsson U.G. Bacterial recolonization of the skin and wound contamination during cardiac surgery: a randomized controlled trial of the use of plastic adhesive drape compared with bare skin. J Hosp Infect 2013, 84:151-158. 10.1016/j.jhin.2013.02.011.
17. Finegold S. Anaerobic bacteria in human disease. Ann Intern Med 1977, 87:501.
18. Fischer N., Mak T.N., Shinohara D.B., Sfanos K.S., Meyer T.F., Bruggemann H. Deciphering the intracellular fate of Propionibacterium acnes in macrophages. Biomed Res Int 2013, 2013:603046. 10.1155/2013/603046.
19. Funke G., von Graevenitz A., Clarridge J.E., Bernard K.A. Clinical microbiology of coryneform bacteria. Clin Microbiol Rev 1997, 10:125-159.
20. Jacobi U., Gautier J., Sterry W., Lademann J. Gender-related differences in the physiology of the stratum corneum. Dermatology 2005, 211:312-317. 10.1159/000088499.
21. Jakab E., Zbinden R., Gubler J., Ruef C., von Graevenitz A., Krause M. Severe infections caused by Propionibacterium acnes: an underestimated pathogen in late postoperative infections. Yale J Biol Med 1996, 69:477-482.
22. Kelly J.D., Hobgood E.R. Positive culture rate in revision shoulder arthroplasty. Clin Orthop Relat Res 2009, 467:2343-2348. 10.1007/s11999-009-0875-x.
23. Koch C.G., Li L., Hixson E., Tang A., Gordon S., Longworth D., et al. Is it time to refine? An exploration and simulation of optimal antibiotic timing in general surgery. J Am Coll Surg 2013, 217:628-635. 10.1016/j.jamcollsurg.2013.05.024.
24. Lange-Asschenfeldt B., Marenbach D., Lang C., Patzelt A., Ulrich M., Maltusch A., et al. Distribution of bacteria in the epidermal layers and hair follicles of the human skin. Skin Pharmacol Physiol 2011, 24:305-311. 10.1159/000328728.
25. Levy O., Iyer S., Atoun E., Peter N., Hous N., Cash D., et al. Propionibacterium acnes: an underestimated etiology in the pathogenesis of osteoarthritis?. J Shoulder Elbow Surg 2013, 22:505-511. 10.1016/j.jse.2012.07.007.
26. Levy P.Y., Fenollar F., Stein A., Borrione F., Cohen E., Lebail B., et al. Propionibacterium acnes postoperative shoulder arthritis: an emerging clinical entity. Clin Infect Dis 2008, 46:1884-1886. 10.1086/588477.
27. Lutz M.F., Berthelot P., Fresard A., Cazorla C., Carricajo A., Vautrin A.C., et al. Arthroplastic and osteosynthetic infections due to Propionibacterium acnes: a retrospective study of 52 cases, 1995-2002. Eur J Clin Microbiol Infect Dis 2005, 24:739-744. 10.1007/s10096-005-0040-8.
28. Mak T.N., Yu S.H., De Marzo A.M., Bruggemann H., Sfanos K.S. Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens. Prostate 2013, 73:770-777. 10.1002/pros.22621.
29. Marples R.R., Leyden J.J., Stewart R.N., Mills O.H., Kligman A.M. The skin microflora in acne vulgaris. J Invest Dermatol 1974, 62:37-41.
30. Martin-Rabadan P., Gijon P., Alcala L., Rodriguez-Creixems M., Alvarado N., Bouza E. Propionibacterium acnes is a common colonizer of intravascular catheters. J Infect 2008, 56:257-260. 10.1016/j.jinf.2008.01.012.
31. Miliani K., L'Hériteau F., Astagneau P., Group I.N.S. Non-compliance with recommendations for the practice of antibiotic prophylaxis and risk of surgical site infection: results of a multilevel analysis from the INCISO Surveillance Network. J Antimicrob Chemother 2009, 64:1307-1315. 10.1093/jac/dkp367.
32. Millett P.J., Yen Y.M., Price C.S., Horan M.P., van der Meijden O.A., Elser F. Propionibacterium acnes infection as an occult cause of postoperative shoulder pain: a case series. Clin Orthop Relat Res 2011, 469:2824-2830. 10.1007/s11999-011-1767-4.
33. Mirzayan R., Itamura J.M., Vangsness C.T., Holtom P.D., Sherman R., Patzakis M.J. Management of chronic deep infection following rotator cuff repair. J Bone Joint Surg Am 2000, 82:1115-1121.
34. Molé D., Wein F., Dézaly C., Valenti P., Sirveaux F. Surgical technique: the anterosuperior approach for reverse shoulder arthroplasty. Clin Orthop Relat Res 2011, 469:2461-2468. 10.1007/s11999-011-1861-7.
35. Patel A., Calfee R.P., Plante M., Fischer S.A., Green A. Propionibacterium acnes colonization of the human shoulder. J Shoulder Elbow Surg 2009, 18:897-902. 10.1016/j.jse.2009.01.023.
36. Perry A., Lambert P. Propionibacterium acnes: infection beyond the skin. Expert Rev Anti Infect Ther 2011, 9:1149-1156. 10.1586/eri.11.137.
37. Perry A.L., Lambert P.A. Propionibacterium acnes. Lett Appl Microbiol 2006, 42:185-188. 10.1111/j.1472-765X.2006.01866.x.
38. Pochi P.E., Strauss J.S. Endocrinologic control of the development and activity of the human sebaceous gland. J Invest Dermatol 1974, 62:191-201.
39. Pottinger P., Butler-Wu S., Neradilek M.B., Merritt A., Bertelsen A., Jette J.L., et al. Prognostic factors for bacterial cultures positive for Propionibacterium acnes and other organisms in a large series of revision shoulder arthroplasties performed for stiffness, pain, or loosening. J Bone Joint Surg Am 2012, 94:2075-2083. 10.2106/JBJS.K.00861.
40. Roh M., Han M., Kim D., Chung K. Sebum output as a factor contributing to the size of facial pores. Br J Dermatol 2006, 155:890-894. 10.1111/j.1365-2133.2006.07465.x.
41. Saltzman M.D., Marecek G.S., Edwards S.L., Kalainov D.M. Infection after shoulder surgery. J Am Acad Orthop Surg 2011, 19:208-218.
42. Schneeberger A.G., Gilbart M.K., Sheikh R., Gerber C., Ruef C. Non-purulent low-grade infection as cause of pain following shoulder surgery: preliminary results. Chir Organi Mov 2009, 93(Suppl 1):S71-S77. 10.1007/s12306-009-0010-x.
43. Shannon S.K., Mandrekar J., Gustafson D.R., Rucinski S.L., Dailey A.L., Segner R.E., et al. Anaerobic thioglycolate broth culture for recovery of Propionibacterium acnes from shoulder tissue and fluid specimens. J Clin Microbiol 2013, 51:731-732. 10.1128/JCM.02695-12.
44. Singh J.A., Sperling J.W., Schleck C., Harmsen W., Cofield R.H. Periprosthetic infections after shoulder hemiarthroplasty. J Shoulder Elbow Surg 2012, 21:1304-1309. 10.1016/j.jse.2011.08.067.
45. Singh J.A., Sperling J.W., Schleck C., Harmsen W.S., Cofield R.H. Periprosthetic infections after total shoulder arthroplasty: a 33-year perspective. J Shoulder Elbow Surg 2012, 21:1534-1541. 10.1016/j.jse.2012.01.006.
46. Sokolove J., Lepus C.M. Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations. Ther Adv Musculoskelet Dis 2013, 5:77-94. 10.1177/1759720X12467868.
47. Sperling J.W., Kozak T.K., Hanssen A.D., Cofield R.H. Infection after shoulder arthroplasty. Clin Orthop Relat Res 2001, 206-216.
48. Suttle C. Crystal ball. The viriosphere: the greatest biological diversity on Earth and driver of global processes. Environ Microbiol 2005, 7:481-482. 10.1111/j.1462-2920.2005.803_11.x.
49. Topolski M.S., Chin P.Y., Sperling J.W., Cofield R.H. Revision shoulder arthroplasty with positive intraoperative cultures: the value of preoperative studies and intraoperative histology. J Shoulder Elbow Surg 2006, 15:402-406. 10.1016/j.jse.2005.10.001.
50. Wacha H., Hoyme U., Isenmann R., Kujath P., Lebert C., Naber K., et al. Perioperative Antibiotika Prophlaxe. Chemotherapie J 2010, 19:70-84.
51. Weber W.P., Marti W.R., Zwahlen M., Misteli H., Rosenthal R., Reck S., et al. The timing of surgical antimicrobial prophylaxis. Ann Surg 2008, 247:918-926. 10.1097/SLA.0b013e31816c3fec.
52. Webster J., Alghamdi A. Use of plastic adhesive drapes during surgery for preventing surgical site infection. Cochrane Database Syst Rev 2013, 1:CD006353. 10.1002/14651858.CD006353.pub3.
53. Whitman W.B., Coleman D.C., Wiebe W.J. Prokaryotes: the unseen majority. Proc Natl Acad Sci U S A 1998, 95:6578-6583.
54. Zeller V., Ghorbani A., Strady C., Leonard P., Mamoudy P., Desplaces N. Propionibacterium acnes: an agent of prosthetic joint infection and colonization. J Infect 2007, 55:119-124. 10.1016/j.jinf.2007.02.006.