VP22 mediates intercellular trafficking and enhances the in vitro antitumor activity of PTEN

Molecular Medicine Reports

Volumn 12, Issue 1, 2015, Pages 1286-1290

  Yu, Xian ^a   Xu, Zhengmin ^b   Lei, Jun ^b   Li, Tingting ^b   Wang, Yan ^b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b AFFILIATED HOSPITAL OF NORTH SICHUAN MEDICAL COLLEGE   (China)

Author keywords

Breast tumor; Fusion proteins; Gene therapy; Intercellular trafficking; PTEN; VP22

Indexed keywords

HYBRID PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN VP22; HERPES SIMPLEX VIRUS TYPE 1 PROTEIN VP22; PTEN PROTEIN, HUMAN; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS ASSAY; ARTICLE; BREAST CARCINOMA; CANCER INHIBITION; CARCINOMA CELL LINE; CELL COMMUNICATION; CELL PROLIFERATION; EXPRESSION VECTOR; FEMALE; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; NONVIRAL GENE THERAPY; PROTEIN PHOSPHORYLATION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HERPES SIMPLEX VIRUS 1; MAMMARY GLAND; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PHOSPHORYLATION; PROCEDURES; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

HUMAN HERPESVIRUS 1;

APOPTOSIS; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; HERPESVIRUS 1, HUMAN; HUMANS; MAMMARY GLANDS, HUMAN; MOLECULAR TARGETED THERAPY; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; VIRAL STRUCTURAL PROTEINS;

EID: 84926663552     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3509     Document Type: Article

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