Thinking clearly about schizotypy: Hewing to the schizophrenia liability core, considering interesting tangents, and avoiding conceptual quicksand

Schizophrenia Bulletin

Volumn 41, Issue , 2015, Pages S483-S491

  Lenzenweger, Mark F ^a,b  

^a BINGHAMTON UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

schizotypy schizophrenia endophenotype liability latent structure schizotype

Indexed keywords

DNA;

ALERTNESS; CONFERENCE PAPER; DEPRESSION; HALLUCINATION; HAPPINESS; HUMAN; MENTAL DISEASE; PANIC; PATHOGENESIS; PERSONALITY; PERSONALITY DISORDER; PHENOTYPE; PRIORITY JOURNAL; PSYCHOMETRY; RISK FACTOR; SCHIZOPHRENIA; SCHIZOTYPAL PERSONALITY DISORDER; SCHIZOTYPY; SOCIAL INTERACTION; CLASSIFICATION;

HUMANS; SCHIZOPHRENIA; SCHIZOTYPAL PERSONALITY DISORDER;

EID: 84926609502     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbu184     Document Type: Conference Paper

References (25)

1. Lenzenweger MF. Psychometric high-risk paradigm, perceptual aberrations, and schizotypy: an update. Schizophr Bull. 1994;20:121-135
2. Lenzenweger MF Schizotypy and schizotypic psychopathology: Mapping an alternative expression of schizophrenia liability. In: Lenzenweger MF, Dworkin RH, eds. Origins and Development of Schizophrenia: Advances in Experimental Psychopathology. Washington, DC: American Psychological Association; 1998:93-121
3. Lenzenweger MF. Schizotypy: an organizing framework for schizophrenia research. Curr Dir Psychol Sci. 2006;15:162-166
4. Lenzenweger MF. Schizotypy and Schizophrenia: the View From Experimental Psychopathology. New York, NY: Guilford Press; 2010
5. Lenzenweger MF. Schizotypic psychopathology: Theory, evidence, and future directions. In Blaney PH, Millon T, Krueger R, eds. Oxford Textbook of Psychopathology (3rd edn). New York, NY: Oxford University Press; 2015:729-767
6. Lenzenweger MF, Loranger AW. Detection of familial schizophrenia using a psychometric measure of schizotypy. Arch Gen Psychiatry. 1989;46:902-907
7. Meehl PE. Schizotaxia, schizotypy, schizophrenia. Am Psychol. 1962;17:827-838
8. Meehl PE. (1990). Toward an integrated theory of schizotaxia, schizotypy, and schizophrenia. J Personal Disord. 1994;4:1-99
9. Lenzenweger MF. Schizotaxia, schizotypy, and schizophrenia: Paul E. Meehls blueprint for the experimental psychopathology and genetics of schizophrenia. J Abnorm Psychol. 2006;115:195-200
10. Fusar-Poli P, Borgwardt S, Bechdolf A, et al. The psychosis high-risk state: a comprehensive state-of-the-art review. JAMA Psychiatry. 2013;70:107-120
11. Arnedo J, Svrakic D, del Val C, Romero-Zaliz R, Hernandez-Cuervo H, Molecular Genetics of Schizophrenia Consortium et al. Uncovering the hidden risk architecture of the schizophrenias: Confirmation in three independent genome-wide association studies. Am J Psychiatry. In press; 2014
12. Raine A, Lencz T, Mednick S. Schizotypal Personality. New York, NY: Cambridge University Press; 1995
13. Kraepelin E. Dementia Praecox and Paraphrenia (Barclay RM, Trans., Robertson GM, ed.). Huntington, NY: Krieger; 1919/1971. (Original work published 1909-1913; original translation of selected portions published 1919
14. Bleuler E. Dementia Praecox or the Group of Schizophrenias. (Zinkin J. Trans.). New York, NY: International Universities Press; 1911/1950
15. Rado, S. (1960). Theory and therapy: the theory of schizotypal organization and its application to the treatment of decompensated schizotypal behavior. In: Scher SC, Davis HR, eds. The Outpatient Treatment of Schizophrenia. New York, NY: Grune and Stratton; 1960:87-101
16. Gottesman II, Gould TD. The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry. 2003;160:636-645
17. Lenzenweger MF. Thinking clearly about the endophenotype-intermediate phenotype-biomarker distinctions in developmental psychopathology research. Dev Psychopathol. 2013;25:1347-1357
18. Schizophrenia Working Group of the Psychiatric Genomics Consortium. (2014). Biological insights from 108 schizophrenia-associated genetic loci. Nature. 2014;511:421-427
19. Gottesman II. Schizophrenia Genesis: The Origins of Madness. New York, NY: W.H. Freeman; 1991
20. Schmidt NB, Kotov R, Lerew DR, Joiner TE, Ialongo NS. Evaluating latent discontinuity in cognitive vulnerability to panic: a taxometric investigation. Cognitive Therapy. 2005; 29:673-690
21. Reise SP, Waller NG. Item response theory and clinical measurement. Annu Rev Clin Psychol. 2009;5:27-48
22. Claridge G. Theoretical background and issues. In: Claridge G. ed., Schizotypy: Implications for Illness and Health. Oxford, UK: Oxford University Press; 1997: 3-18
23. Rawlings D, Williams B, Haslam N, Claridge, G. Taxometric analysis supports a dimensional latent structure for schizotypy. Person Indiv Differ. 2008;44:1640-1651
24. Krueger RF, Derringer J, Markon KE, Watson D, Skodol A. Initial construction of a maladaptive personality trait model and inventory for DSM-5. Psychol Med. 2012;42:1879-1890
25. Lenzenweger MF, McLachlan G, Rubin DB. Resolving the latent structure of schizophrenia endophenotypes using expectation-maximization-based finite mixture modeling. J Abnorm Psychol. 2007;116:16-29