Tumor-targeted delivery of paclitaxel using low density lipoprotein-mimetic solid lipid nanoparticles

Molecular Pharmaceutics

Volumn 12, Issue 4, 2015, Pages 1230-1241

  Kim, Jin Ho ^a,b   Kim, Youngwook ^a   Bae, Ki Hyun ^c   Park, Tae Gwan ^c   Lee, Jung Hee ^b,d   Park, Keunchil ^a,d  

^a Samsung Medical Center   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

^d Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

cancer therapy; paclitaxel; solid lipid nanoparticles; targeted drug delivery system; tumor targeting

Indexed keywords

LOW DENSITY LIPOPROTEIN; MACROGOL; PACLITAXEL; SOLID LIPID NANOPARTICLE; ANTINEOPLASTIC AGENT; BIOMATERIAL; DRUG CARRIER; LIPID; MACROGOL DERIVATIVE; NANOPARTICLE; WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CONTROLLED STUDY; COVALENT BOND; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; FEMALE; IN VIVO STUDY; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; BIOMIMETICS; CANCER TRANSPLANTATION; CHEMISTRY; HUMAN; NANOMEDICINE; NUDE MOUSE; SOLUBILITY; TUMOR CELL LINE;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOCOMPATIBLE MATERIALS; BIOMIMETICS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; LIPIDS; LIPOPROTEINS, LDL; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOMEDICINE; NANOPARTICLES; NEOPLASM TRANSPLANTATION; PACLITAXEL; POLYETHYLENE GLYCOLS; SOLUBILITY; WATER;

EID: 84926483086     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500737y     Document Type: Article

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