Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage

Nature Immunology

Volumn 15, Issue 12, 2014, Pages 1116-1125

  Sutherland, Tara E ^a   Logan, Nicola ^a   Rückerl, Dominik ^a   Humbles, Alison A ^b   Allan, Stuart M ^c   Papayannopoulos, Venizelos ^d   Stockinger, Brigitta ^d   Maizels, Rick M ^a   Allen, Judith E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b MEDIMMUNE   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRP 39; CHITINASE; CHITINASE LIKE PROTEIN; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 23; MESSENGER RNA; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; YM1; YM2; BETA N ACETYLHEXOSAMINIDASE; CHI3L3 PROTEIN, MOUSE; CHITINASE 3-LIKE 1, MOUSE; GLYCOPROTEIN; LECTIN; YM2 PROTEIN, MOUSE;

ALLERGIC AIRWAY INFLAMMATION; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GAMMA DELTA T LYMPHOCYTE; HOST RESISTANCE; IMMUNE RESPONSE; INNATE IMMUNITY; LUNG INJURY; LUNG LAVAGE; MOUSE; NEMATODIASIS; NEUTROPHIL; NEUTROPHILIA; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PARASITE SURVIVAL; PERITONEUM MACROPHAGE; PROTEIN EXPRESSION; TH2 CELL; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; IMMUNOLOGY; INFLAMMATION; NEMATODE; NEUTROPHIL CHEMOTAXIS; REAL TIME POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

ANIMALS; BETA-N-ACETYLHEXOSAMINIDASES; CHITINASE; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOPROTEINS; IMMUNITY, INNATE; INFLAMMATION; INTERLEUKIN-17; LECTINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NEMATODA; NEMATODE INFECTIONS; NEUTROPHIL INFILTRATION; NEUTROPHILS; REAL-TIME POLYMERASE CHAIN REACTION; T-LYMPHOCYTES; TRANSFECTION;

EID: 84911143445     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3023     Document Type: Article

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