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Volumn 156, Issue 4, 2015, Pages 1228-1236

Androgens regulate bone marrow B lymphopoiesis in male mice by targeting osteoblast-lineage cells

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANDROGEN; BIOLOGICAL MARKER; COLLAGEN TYPE 1; COLLAGEN TYPE I TRIMERIC CROSS-LINKED PEPTIDE; OSTEOCALCIN; PEPTIDE;

EID: 84926444092     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1822     Document Type: Article
Times cited : (17)

References (43)
  • 1
    • 84858753127 scopus 로고    scopus 로고
    • Sex differences and genomics in autoimmune diseases
    • Amur S, Parekh A, Mummaneni P. Sex differences and genomics in autoimmune diseases. J Autoimmun. 2012;38:J254-J265.
    • (2012) J Autoimmun , vol.38 , pp. J254-J265
    • Amur, S.1    Parekh, A.2    Mummaneni, P.3
  • 2
    • 34547792318 scopus 로고    scopus 로고
    • The complex role of estrogens in inflammation
    • Straub RH. The complex role of estrogens in inflammation. Endocr Rev. 2007;28:521-574.
    • (2007) Endocr Rev , vol.28 , pp. 521-574
    • Straub, R.H.1
  • 3
    • 84858447329 scopus 로고    scopus 로고
    • The influence of sex and gender on the immune response
    • Oertelt-Prigione S. The influence of sex and gender on the immune response. Autoimmun Rev. 2012;11:A479-A485.
    • (2012) Autoimmun Rev , vol.11 , pp. A479-A485
    • Oertelt-Prigione, S.1
  • 4
    • 0017644226 scopus 로고
    • Androgenic hormones modulate autoantibody responses and improve survival in murine lupus
    • Roubinian JR, Papoian R, Talal N. Androgenic hormones modulate autoantibody responses and improve survival in murine lupus. J Clin Invest. 1977;59:1066-1070.
    • (1977) J Clin Invest , vol.59 , pp. 1066-1070
    • Roubinian, J.R.1    Papoian, R.2    Talal, N.3
  • 5
    • 0018152085 scopus 로고
    • Effect of castration and sex hormone treatment on survival, antinucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice
    • Roubinian JR, Talal N, Greenspan JS, Goodman JR, Siiteri PK. Effect of castration and sex hormone treatment on survival, antinucleic acid antibodies, and glomerulonephritis in NZB/NZW F1 mice. J Exp Med. 1978;147:1568-1583.
    • (1978) J Exp Med , vol.147 , pp. 1568-1583
    • Roubinian, J.R.1    Talal, N.2    Greenspan, J.S.3    Goodman, J.R.4    Siiteri, P.K.5
  • 6
    • 64749088085 scopus 로고    scopus 로고
    • Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells
    • Altuwaijri S, Chuang KH, Lai KP, et al. Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells. Mol Endocrinol. 2009;23:444-453.
    • (2009) Mol Endocrinol , vol.23 , pp. 444-453
    • Altuwaijri, S.1    Chuang, K.H.2    Lai, K.P.3
  • 7
    • 0028962781 scopus 로고
    • Enhanced production of B lymphocytes after castration
    • Wilson CA, Mrose SA, Thomas DW. Enhanced production of B lymphocytes after castration. Blood. 1995;85:1535-1539.
    • (1995) Blood , vol.85 , pp. 1535-1539
    • Wilson, C.A.1    Mrose, S.A.2    Thomas, D.W.3
  • 9
    • 0031830892 scopus 로고    scopus 로고
    • The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis
    • Smithson G, Couse JF, Lubahn DB, Korach KS, Kincade PW. The role of estrogen receptors and androgen receptors in sex steroid regulation of B lymphopoiesis. J Immunol. 1998;161:27-34.
    • (1998) J Immunol , vol.161 , pp. 27-34
    • Smithson, G.1    Couse, J.F.2    Lubahn, D.B.3    Korach, K.S.4    Kincade, P.W.5
  • 10
    • 0035071529 scopus 로고    scopus 로고
    • Alterations in peripheral B cells and B cell progenitors following androgen ablation in mice
    • Ellis TM, Moser MT, Le PT, Flanigan RC, Kwon ED. Alterations in peripheral B cells and B cell progenitors following androgen ablation in mice. Int Immunol. 2001;13:553-558.
    • (2001) Int Immunol , vol.13 , pp. 553-558
    • Ellis, T.M.1    Moser, M.T.2    Le, P.T.3    Flanigan, R.C.4    Kwon, E.D.5
  • 11
    • 0035210027 scopus 로고    scopus 로고
    • Bone marrow stromal cells mediate androgenic suppression of B lymphocyte development
    • Olsen NJ, Gu X, Kovacs WJ. Bone marrow stromal cells mediate androgenic suppression of B lymphocyte development. J Clin Invest. 2001;108:1697-1704.
    • (2001) J Clin Invest , vol.108 , pp. 1697-1704
    • Olsen, N.J.1    Gu, X.2    Kovacs, W.J.3
  • 12
    • 0034983089 scopus 로고    scopus 로고
    • Effects of androgens on T and B lymphocyte development
    • Olsen NJ, Kovacs WJ. Effects of androgens on T and B lymphocyte development. Immunol Res. 2001;23:281-288.
    • (2001) Immunol Res , vol.23 , pp. 281-288
    • Olsen, N.J.1    Kovacs, W.J.2
  • 14
    • 65949115924 scopus 로고    scopus 로고
    • Role of the osteoblast lineage in the bone marrow hematopoietic niches
    • Wu JY, Scadden DT, Kronenberg HM. Role of the osteoblast lineage in the bone marrow hematopoietic niches. J Bone Miner Res. 2009; 24:759-764.
    • (2009) J Bone Miner Res , vol.24 , pp. 759-764
    • Wu, J.Y.1    Scadden, D.T.2    Kronenberg, H.M.3
  • 15
    • 10744226931 scopus 로고    scopus 로고
    • A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis
    • De Gendt K, Swinnen JV, Saunders PT, et al. A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. Proc Natl Acad Sci USA. 2004;101:1327-1332.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 1327-1332
    • De Gendt, K.1    Swinnen, J.V.2    Saunders, P.T.3
  • 16
    • 0032030846 scopus 로고    scopus 로고
    • Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase
    • Lallemand Y, Luria V, Haffner-Krausz R, Lonai P. Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase. Transgenic Res. 1998;7:105-112.
    • (1998) Transgenic Res , vol.7 , pp. 105-112
    • Lallemand, Y.1    Luria, V.2    Haffner-Krausz, R.3    Lonai, P.4
  • 17
    • 78049516208 scopus 로고    scopus 로고
    • Androgen receptor-dependent and independent atheroprotection by testosterone in male mice
    • Bourghardt J, Wilhelmson AS, Alexanderson C, et al. Androgen receptor-dependent and independent atheroprotection by testosterone in male mice. Endocrinology. 2010;151:5428-5437.
    • (2010) Endocrinology , vol.151 , pp. 5428-5437
    • Bourghardt, J.1    Wilhelmson, A.S.2    Alexanderson, C.3
  • 18
    • 33748768971 scopus 로고    scopus 로고
    • Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
    • Rodda SJ, McMahon AP. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development. 2006;133:3231-3244.
    • (2006) Development , vol.133 , pp. 3231-3244
    • Rodda, S.J.1    McMahon, A.P.2
  • 19
    • 84864029795 scopus 로고    scopus 로고
    • Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual
    • Davey RA, Clarke MV, Sastra S, et al. Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual. Transgenic Res. 2012;21:885-893.
    • (2012) Transgenic Res , vol.21 , pp. 885-893
    • Davey, R.A.1    Clarke, M.V.2    Sastra, S.3
  • 20
    • 84900309835 scopus 로고    scopus 로고
    • Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development
    • Mizoguchi T, Pinho S, Ahmed J, et al. Osterix marks distinct waves of primitive and definitive stromal progenitors during bone marrow development. Dev Cell. 2014;29:340-349.
    • (2014) Dev Cell , vol.29 , pp. 340-349
    • Mizoguchi, T.1    Pinho, S.2    Ahmed, J.3
  • 21
    • 0031907808 scopus 로고    scopus 로고
    • Murine B lymphopoiesis: Towards a unified model
    • Osmond DG, Rolink A, Melchers F. Murine B lymphopoiesis: towards a unified model. Immunol Today. 1998;19:65-68.
    • (1998) Immunol Today , vol.19 , pp. 65-68
    • Osmond, D.G.1    Rolink, A.2    Melchers, F.3
  • 22
    • 0035892228 scopus 로고    scopus 로고
    • Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
    • Allman D, Lindsley RC, DeMuth W, Rudd K, Shinton SA, Hardy RR. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J Immunol. 2001;167:6834-6840.
    • (2001) J Immunol , vol.167 , pp. 6834-6840
    • Allman, D.1    Lindsley, R.C.2    DeMuth, W.3    Rudd, K.4    Shinton, S.A.5    Hardy, R.R.6
  • 23
  • 24
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-ΔΔC(T)) method. Methods. 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 25
    • 0034625044 scopus 로고    scopus 로고
    • Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice
    • Vidal O, Lindberg MK, Hollberg K, et al. Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice. Proc Natl Acad Sci USA. 2000;97:5474-5479.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5474-5479
    • Vidal, O.1    Lindberg, M.K.2    Hollberg, K.3
  • 26
    • 34247332650 scopus 로고    scopus 로고
    • Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells
    • Zhu J, Garrett R, Jung Y, et al. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood. 2007;109:3706-3712.
    • (2007) Blood , vol.109 , pp. 3706-3712
    • Zhu, J.1    Garrett, R.2    Jung, Y.3
  • 28
    • 1942457308 scopus 로고    scopus 로고
    • Hematopoiesis is severely altered in mice with an induced osteoblast deficiency
    • Visnjic D, Kalajzic Z, Rowe DW, Katavic V, Lorenzo J, Aguila HL. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. Blood. 2004;103:3258-3264.
    • (2004) Blood , vol.103 , pp. 3258-3264
    • Visnjic, D.1    Kalajzic, Z.2    Rowe, D.W.3    Katavic, V.4    Lorenzo, J.5    Aguila, H.L.6
  • 29
    • 55949114758 scopus 로고    scopus 로고
    • Osteoblastic regulation of B lymphopoiesis is mediated by Gsα-dependent signaling pathways
    • Wu JY, Purton LE, Rodda SJ, et al. Osteoblastic regulation of B lymphopoiesis is mediated by Gsα-dependent signaling pathways. Proc Natl Acad Sci USA. 2008;105:16976-16981.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16976-16981
    • Wu, J.Y.1    Purton, L.E.2    Rodda, S.J.3
  • 30
    • 84874997081 scopus 로고    scopus 로고
    • CXCL12 in early mesendoi: Chymal progenitors is required for haematopoietic stem-cell maintenance
    • Greenbaum A, Hsu YM, Day RB, et al. CXCL12 in early mesendoi: chymal progenitors is required for haematopoietic stem-cell maintenance. Nature. 2013;495:227-230.
    • (2013) Nature , vol.495 , pp. 227-230
    • Greenbaum, A.1    Hsu, Y.M.2    Day, R.B.3
  • 31
    • 84875000886 scopus 로고    scopus 로고
    • Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
    • Ding L, Morrison SJ. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature. 2013;495:231-235.
    • (2013) Nature , vol.495 , pp. 231-235
    • Ding, L.1    Morrison, S.J.2
  • 32
    • 33644845081 scopus 로고    scopus 로고
    • Microenvironmental niches in the bone marrow required for B-cell development
    • Nagasawa T. Microenvironmental niches in the bone marrow required for B-cell development. Nat Rev Immunol. 2006;6:107-116.
    • (2006) Nat Rev Immunol , vol.6 , pp. 107-116
    • Nagasawa, T.1
  • 33
    • 66049147305 scopus 로고    scopus 로고
    • Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor
    • Chuang KH, Altuwaijri S, Li G, et al. Neutropenia with impaired host defense against microbial infection in mice lacking androgen receptor. J Exp Med. 2009;206:1181-1199.
    • (2009) J Exp Med , vol.206 , pp. 1181-1199
    • Chuang, K.H.1    Altuwaijri, S.2    Li, G.3
  • 34
    • 70249085585 scopus 로고    scopus 로고
    • Stromal cell contributions to the homeostasis and functionality of the immune system
    • Mueller SN, Germain RN. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat Rev Immunol. 2009;9:618-629.
    • (2009) Nat Rev Immunol , vol.9 , pp. 618-629
    • Mueller, S.N.1    Germain, R.N.2
  • 35
    • 65549171025 scopus 로고    scopus 로고
    • Mineralization and bone resorption are regulated by the androgen receptor in male mice
    • Chiang C, Chiu M, Moore AJ, et al. Mineralization and bone resorption are regulated by the androgen receptor in male mice. J Bone Miner Res. 2009;24:621-631.
    • (2009) J Bone Miner Res , vol.24 , pp. 621-631
    • Chiang, C.1    Chiu, M.2    Moore, A.J.3
  • 36
    • 34247192540 scopus 로고    scopus 로고
    • Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice
    • Notini AJ, McManus JF, Moore A, et al. Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice. J Bone Miner Res. 2007;22:347-356.
    • (2007) J Bone Miner Res , vol.22 , pp. 347-356
    • Notini, A.J.1    McManus, J.F.2    Moore, A.3
  • 37
    • 84869397973 scopus 로고    scopus 로고
    • Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: Evidence from targeted AR disruption in mouse osteocytes
    • Sinnesael M, Claessens F, Laurent M, et al. Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes. J Bone Miner Res. 2012;27:2535-2543.
    • (2012) J Bone Miner Res , vol.27 , pp. 2535-2543
    • Sinnesael, M.1    Claessens, F.2    Laurent, M.3
  • 38
    • 84888205228 scopus 로고    scopus 로고
    • The role of estrogen and androgen receptors in bone health and disease
    • Manolagas SC, O'Brien CA, Almeida M. The role of estrogen and androgen receptors in bone health and disease. Nat Rev Endocrinol. 2013;9:699-712.
    • (2013) Nat Rev Endocrinol , vol.9 , pp. 699-712
    • Manolagas, S.C.1    O'Brien, C.A.2    Almeida, M.3
  • 39
    • 0029875771 scopus 로고    scopus 로고
    • Androgens in men-uses and abuses
    • Bagatell CJ, Bremner WJ. Androgens in men-uses and abuses. N Engl J Med. 1996;334:707-714.
    • (1996) N Engl J Med , vol.334 , pp. 707-714
    • Bagatell, C.J.1    Bremner, W.J.2
  • 40
    • 0033851490 scopus 로고    scopus 로고
    • The effect of testosterone replacement treatment on immunological features of patients with Klinefelter's syndrome
    • Koçar IH, Yesilova Z, Ozata M, Turan M, Sengül A, Ozdemir I. The effect of testosterone replacement treatment on immunological features of patients with Klinefelter's syndrome. Clin Exp Immunol. 2000;121:448-452.
    • (2000) Clin Exp Immunol , vol.121 , pp. 448-452
    • Koçar, I.H.1    Yesilova, Z.2    Ozata, M.3    Turan, M.4    Sengül, A.5    Ozdemir, I.6
  • 41
    • 84878621952 scopus 로고    scopus 로고
    • Testosterone is protective in the sexually dimorphic development of arthritis and lung disease in SKG mice
    • Keith RC, Sokolove J, Edelman BL, et al. Testosterone is protective in the sexually dimorphic development of arthritis and lung disease in SKG mice. Arthritis Rheum. 2013;65:1487-1493.
    • (2013) Arthritis Rheum , vol.65 , pp. 1487-1493
    • Keith, R.C.1    Sokolove, J.2    Edelman, B.L.3
  • 42
    • 79955540987 scopus 로고    scopus 로고
    • Testosterone replacement effectively inhibits the development of experimental autoimmune orchitis in rats: Evidence for a direct role of testosterone on regulatory T cell expansion
    • Fijak M, Schneider E, Klug J, et al. Testosterone replacement effectively inhibits the development of experimental autoimmune orchitis in rats: evidence for a direct role of testosterone on regulatory T cell expansion. J Immunol. 2011;186:5162-5172.
    • (2011) J Immunol , vol.186 , pp. 5162-5172
    • Fijak, M.1    Schneider, E.2    Klug, J.3
  • 43
    • 84908135475 scopus 로고    scopus 로고
    • Transcriptional and metabolic pre-B cell receptor-mediated checkpoints: Implications for autoimmune diseases
    • Zouali M. Transcriptional and metabolic pre-B cell receptor-mediated checkpoints: implications for autoimmune diseases. Mol Immunol. 2014;62:315-320.
    • (2014) Mol Immunol , vol.62 , pp. 315-320
    • Zouali, M.1


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