Hydrogen sulfide regulates the colonic motility by inhibiting both L-type calcium channels and BKCa channels in smooth muscle cells of rat colon

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Quan, Xiaojing ^a   Luo, Hesheng ^a   Liu, Yin ^b   Xia, Hong ^a,c   Chen, Wei ^a   Tang, Qincai ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b GUILIN MEDICAL UNIVERSITY   (China)

^c Key Laboratory of Hubei Province for Digestive System Disease   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL L TYPE; CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; HYDROGEN SULFIDE; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; SODIUM HYDROSULFIDE; SULFIDE; TETRODOTOXIN; UNCLASSIFIED DRUG; CALCIUM CHANNEL BLOCKING AGENT; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CALCIUM CURRENT; CALCIUM HOMEOSTASIS; CELL ISOLATION; COLON MOTILITY; CONTRACTION ASSAY; CONTROLLED STUDY; ENZYME LOCALIZATION; IMMUNOHISTOCHEMISTRY; INTESTINE MUSCLE; MALE; MEMBRANE POTENTIAL; MYENTERIC PLEXUS; NONHUMAN; RAT; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; WHOLE CELL PATCH CLAMP; WISTAR RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; COLON; DOSE RESPONSE; DRUG EFFECTS; GASTROINTESTINAL MOTILITY; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE CELL;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; COLON; CYSTATHIONINE BETA-SYNTHASE; CYSTATHIONINE GAMMA-LYASE; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL MOTILITY; HYDROGEN SULFIDE; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNITS; MALE; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; RATS;

EID: 84926435991     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121331     Document Type: Article

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