Actions of Hydrogen Sulfide and ATP-Sensitive Potassium Channels on Colonic Hypermotility in a Rat Model of Chronic Stress

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Liu, Ying ^a,b   Luo, Hesheng ^a   Liang, Chengbo ^a   Xia, Hong ^a   Xu, Wenjuan ^a   Chen, Jihong ^a   Chen, Mingkai ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b GUILIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; HYDROGEN SULFIDE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR 2B; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC STRESS; CONTROLLED STUDY; DOWN REGULATION; EXPERIMENTAL TEST; IMMUNOHISTOCHEMISTRY; INTESTINAL DYSMOTILITY; MALE; NONHUMAN; PATHOGENESIS; RAT; SHAM AVOIDANCE STRESS TEST; UPREGULATION; WATER AVOIDANCE STRESS TEST; WESTERN BLOTTING;

AIR POLLUTANTS; ANIMALS; BLOTTING, WESTERN; CHRONIC DISEASE; COLON; GASTROINTESTINAL MOTILITY; HYDROGEN SULFIDE; IMMUNOENZYME TECHNIQUES; KATP CHANNELS; MALE; MUSCLE CONTRACTION; RATS; RATS, WISTAR; STRESS, PSYCHOLOGICAL; WATER;

EID: 84873560111     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055853     Document Type: Article

References (38)

1. Konturek PC, Brzozowski T, Konturek SJ, (2011) Stress and the gut: pathophysiology, clinical consequences, diagnostic approach and treatment options. J Physiol Pharmacol 62: 591-599.
2. Liang C, Luo H, Liu Y, Cao J, Xia H, (2012) Plasma hormones facilitated the hypermotility of the colon in a chronic stress rat model. PLoS One 7: e31774.
3. Bradesi S, Schwetz I, Ennes HS, Lamy CM, Ohning G, et al. (2005) Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia. Am J Physiol Gastrointest Liver Physiol 289: G42-53.
4. Choudhury BK, Shi XZ, Sarna SK, (2009) Norepinephrine mediates the transcriptional effects of heterotypic chronic stress on colonic motor function. Am J Physiol Gastrointest Liver Physiol 296: G1238-1247.
5. Ataka K, Nagaishi K, Asakawa A, Inui A, Fujimiya M, (2012) Alteration of antral and proximal colonic motility induced by chronic psychological stress involves central urocortin 3 and vasopressin in rats. Am J Physiol Gastrointest Liver Physiol 303: G519-528.
6. Bulbul M, Babygirija R, Cerjak D, Yoshimoto S, Ludwig K, et al. (2012) Impaired adaptation of gastrointestinal motility following chronic stress in maternally separated rats. Am J Physiol Gastrointest Liver Physiol 302: G702-711.
7. Li Q, Sarna SK, (2011) Chronic stress targets posttranscriptional mechanisms to rapidly upregulate alpha1C-subunit of Cav1.2b calcium channels in colonic smooth muscle cells. Am J Physiol Gastrointest Liver Physiol 300: G154-163.
8. Zhang M, Leung FP, Huang Y, Bian ZX, (2010) Increased colonic motility in a rat model of irritable bowel syndrome is associated with up-regulation of L-type calcium channels in colonic smooth muscle cells. Neurogastroenterol Motil 22: e162-170.
9. Szabo C, (2007) Hydrogen sulphide and its therapeutic potential. Nat Rev Drug Discov 6: 917-935.
10. Jimenez M, (2010) Hydrogen sulfide as a signaling molecule in the enteric nervous system. Neurogastroenterol Motil 22: 1149-1153.
11. Fiorucci S, Distrutti E, Cirino G, Wallace JL, (2006) The emerging roles of hydrogen sulfide in the gastrointestinal tract and liver. Gastroenterology 131: 259-271.
12. Linden DR, Levitt MD, Farrugia G, Szurszewski JH, (2010) Endogenous production of H2S in the gastrointestinal tract: still in search of a physiologic function. Antioxid Redox Signal 12: 1135-1146.
13. Teague B, Asiedu S, Moore PK, (2002) The smooth muscle relaxant effect of hydrogen sulphide in vitro: evidence for a physiological role to control intestinal contractility. Br J Pharmacol 137: 139-145.
14. Gallego D, Clave P, Donovan J, Rahmati R, Grundy D, et al. (2008) The gaseous mediator, hydrogen sulphide, inhibits in vitro motor patterns in the human, rat and mouse colon and jejunum. Neurogastroenterol Motil 20: 1306-1316.
15. Zhao P, Huang X, Wang ZY, Qiu ZX, Han YF, et al. (2009) Dual effect of exogenous hydrogen sulfide on the spontaneous contraction of gastric smooth muscle in guinea-pig. Eur J Pharmacol 616: 223-228.
16. Dhaese I, Lefebvre RA, (2009) Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus. Eur J Pharmacol 606: 180-186.
17. Dhaese I, Van Colen I, Lefebvre RA, (2010) Mechanisms of action of hydrogen sulfide in relaxation of mouse distal colonic smooth muscle. Eur J Pharmacol 628: 179-186.
18. Distrutti E, Sediari L, Mencarelli A, Renga B, Orlandi S, et al. (2006) Evidence that hydrogen sulfide exerts antinociceptive effects in the gastrointestinal tract by activating KATP channels. J Pharmacol Exp Ther 316: 325-335.
19. Teramoto N, (2006) Physiological roles of ATP-sensitive K+ channels in smooth muscle. J Physiol 572: 617-624.
20. Flagg TP, Enkvetchakul D, Koster JC, Nichols CG, (2010) Muscle KATP channels: recent insights to energy sensing and myoprotection. Physiol Rev 90: 799-829.
21. Jin X, Malykhina AP, Lupu F, Akbarali HI, (2004) Altered gene expression and increased bursting activity of colonic smooth muscle ATP-sensitive K+ channels in experimental colitis. Am J Physiol Gastrointest Liver Physiol 287: G274-285.
22. Koh SD, Bradley KK, Rae MG, Keef KD, Horowitz B, et al. (1998) Basal activation of ATP-sensitive potassium channels in murine colonic smooth muscle cell. Biophys J 75: 1793-1800.
23. Jun JY, Kong ID, Koh SD, Wang XY, Perrino BA, et al. (2001) Regulation of ATP-sensitive K(+) channels by protein kinase C in murine colonic myocytes. Am J Physiol Cell Physiol 281: C857-864.
24. Pluja L, Yokoshiki H, Sperelakis N, (1998) Evidence for presence of ATP-sensitive K+ channels in rat colonic smooth muscle cells. Can J Physiol Pharmacol 76: 1166-1170.
25. Tian XY, Bian ZX, Hu XG, Zhang XJ, Liu L, et al. (2006) Electro-acupuncture attenuates stress-induced defecation in rats with chronic visceral hypersensitivity via serotonergic pathway. Brain Res 1088: 101-108.
26. Gil V, Gallego D, Jimenez M, (2011) Effects of inhibitors of hydrogen sulphide synthesis on rat colonic motility. Br J Pharmacol 164: 485-498.
27. Linden DR, Sha L, Mazzone A, Stoltz GJ, Bernard CE, et al. (2008) Production of the gaseous signal molecule hydrogen sulfide in mouse tissues. J Neurochem 106: 1577-1585.
28. Wallace JL, Dicay M, McKnight W, Martin GR, (2007) Hydrogen sulfide enhances ulcer healing in rats. FASEB J 21: 4070-4076.
29. Hennig B, Diener M, (2009) Actions of hydrogen sulphide on ion transport across rat distal colon. Br J Pharmacol 158: 1263-1275.
30. Kasparek MS, Linden DR, Farrugia G, Sarr MG, (2012) Hydrogen sulfide modulates contractile function in rat jejunum. J Surg Res 175: 234-242.
31. Martin GR, McKnight GW, Dicay MS, Coffin CS, Ferraz JG, et al. (2010) Hydrogen sulphide synthesis in the rat and mouse gastrointestinal tract. Dig Liver Dis 42: 103-109.
32. Wallace JL, Vong L, McKnight W, Dicay M, Martin GR (2009) Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. Gastroenterology 137: 569-578, 578 e561.
33. Hansen MB, (2003) The enteric nervous system II: gastrointestinal functions. Pharmacol Toxicol 92: 249-257.
34. Xu GY, Winston JH, Shenoy M, Zhou S, Chen JD, et al. (2009) The endogenous hydrogen sulfide producing enzyme cystathionine-beta synthase contributes to visceral hypersensitivity in a rat model of irritable bowel syndrome. Mol Pain 5: 44.
35. Hosoki R, Matsuki N, Kimura H, (1997) The possible role of hydrogen sulfide as an endogenous smooth muscle relaxant in synergy with nitric oxide. Biochem Biophys Res Commun 237: 527-531.
36. Paravicini TM, Sobey CG, (2003) Cerebral vascular effects of reactive oxygen species: recent evidence for a role of NADPH-oxidase. Clin Exp Pharmacol Physiol 30: 855-859.
37. Leffler CW, Parfenova H, Jaggar JH, Wang R, (2006) Carbon monoxide and hydrogen sulfide: gaseous messengers in cerebrovascular circulation. J Appl Physiol 100: 1065-1076.
38. Fiorucci S, Orlandi S, Mencarelli A, Caliendo G, Santagada V, et al. (2007) Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis. Br J Pharmacol 150: 996-1002.