Ultra-Sensitive Detection of Plasmodium falciparum by Amplification of Multi-Copy Subtelomeric Targets

PLoS Medicine

Volumn 12, Issue 3, 2015, Pages

  Hofmann, Natalie ^a,b   Mwingira, Felista ^a,b,c   Shekalaghe, Seif ^d   Robinson, Leanne J ^e,f,g   Mueller, Ivo ^f,g,h   Felger, Ingrid ^a,b  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c UNIVERSITY OF DAR ES SALAAM   (Tanzania)

^d IFAKARA HEALTH INSTITUTE   (Tanzania)

^e PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

^f WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

^h CENTRE FOR RESEARCH IN ENVIRONMENTAL EPIDEMIOLOGY CREAL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOSOME RNA; PROTOZOAL DNA; RNA 18S;

ARTICLE; CROSS-SECTIONAL STUDY; DNA STRUCTURE; GAMETOCYTE; GENE AMPLIFICATION; GENE SEQUENCE; HUMAN; LIMIT OF DETECTION; MAJOR CLINICAL STUDY; MALARIA; MICROORGANISM DETECTION; PARASITE LOAD; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PREVALENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEQUENCE ALIGNMENT; TELOMERE ASSOCIATED REPETITIVE ELEMENT 2; VAR GENE ACIDIC TERMINAL SEQUENCE; BLOOD; GENETICS; MALARIA, FALCIPARUM; MICROSCOPY; MOLECULAR DIAGNOSIS; MOLECULAR EPIDEMIOLOGY; NUCLEIC ACID AMPLIFICATION; NUCLEOTIDE REPEAT; PARASITOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; TANZANIA; TELOMERE; TRANSMISSION;

CROSS-SECTIONAL STUDIES; DNA, PROTOZOAN; HUMANS; MALARIA, FALCIPARUM; MICROSCOPY; MOLECULAR DIAGNOSTIC TECHNIQUES; MOLECULAR EPIDEMIOLOGY; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PLASMODIUM FALCIPARUM; PREVALENCE; REAL-TIME POLYMERASE CHAIN REACTION; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, RIBOSOMAL, 18S; TANZANIA; TELOMERE;

EID: 84926435530     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1001788     Document Type: Article

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