Structure determination of murine norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions

PeerJ

Volumn 2015, Issue 2, 2015, Pages

  Fernandes, Humberto ^b   Leen, Eoin N ^a   Cromwell, Hamlet ^a   Pfeil, Marc Philipp ^c   Curry, Stephen ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Anisotropic diffraction; Crystal contacts; Crystal structure; Data processing; Elliptical truncation; R factors; Refinement

Indexed keywords

NS6 PROTEASE; PROTEINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANISOTROPY; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; NOROVIRUS; NUCLEAR MAGNETIC RESONANCE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

MURINE NOROVIRUS; RNA VIRUSES;

EID: 84926431475     PISSN: None     EISSN: 21678359     Source Type: Journal    
DOI: 10.7717/peerj.798     Document Type: Article

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