Outer membrane proteins preferentially load MHC class II peptides: Implications for a Chlamydia trachomatis T cell vaccine

Vaccine

Volumn 33, Issue 18, 2015, Pages 2159-2166

  Karunakaran, Karuna P ^a   Yu, Hong ^a   Jiang, Xiaozhou ^a   Chan, Queenie ^b   Moon, Kyung Mee ^b   Foster, Leonard J ^b   Brunham, Robert C ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Antigen; Chlamydia; Epitope; Immunoproteomics; MHC; Outer membrane proteins; Peptide; T cell; Vaccine

Indexed keywords

3 KETOACYL (ACYL CARRIER PROTEIN) REDUCTASE; 50S RIBOSOMAL PROTEIN L21 33; 50S RIBOSOMAL PROTEIN L6; BACTERIAL PROTEIN; BACTERIAL VACCINE; CHAPERONIN GROEL1 41; CHLAMYDIA TRACHOMATIS T CELL VACCINE; CHLPN 76 KDA HOMOLOG; CYTOSOL AMINOPEPTIDASE; DIHYDROLIPOAMIDE ACETYLTRANSFERASE 51; ENDOPEPTIDASE CLP; EPITOPE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HYPOTHETICAL PROTEIN; HYPOTHETICAL PROTEIN 33; HYPOTHETICAL PROTEIN 60; IMMUNOLOGICAL ADJUVANT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MAJOR OUTER MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN; POLYMORPHIC MEMBRANE PROTEIN F; POLYMORPHIC MEMBRANE PROTEIN G; POLYMORPHIC MEMBRANE PROTEIN H; PREDICTED DEXTRO AMINO ACID DEHYDROGENASE; RECOMBINANT PROTEIN; RECOMBINANT VACCINE; SUBUNIT VACCINE; T LYMPHOCYTE ANTIGEN; TYPE III SECRETION TRANSLOCASE 46; UNCLASSIFIED DRUG; YOP PROTEINS TRANSLOCATION LIPOPROTEIN; BACTERIUM ANTIBODY; HLA ANTIGEN CLASS 2; PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL IMMUNITY; BONE MARROW DERIVED DENDRITIC CELL; CD4+ T LYMPHOCYTE; CHLAMYDIA; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; HELA CELL LINE; IMMUNE RESPONSE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PURIFICATION; PROTEOMICS; SPLEEN CELL; TANDEM MASS SPECTROMETRY; TH1 CELL; VACCINATION; ANIMAL; C3H MOUSE; C57BL MOUSE; CHEMISTRY; CHLAMYDIA MURIDARUM; DENDRITIC CELL; HUMAN; IMMUNOLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL VACCINES; CD4-POSITIVE T-LYMPHOCYTES; CHLAMYDIA INFECTIONS; CHLAMYDIA MURIDARUM; CHLAMYDIA TRACHOMATIS; DENDRITIC CELLS; EPITOPES; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; PEPTIDES; PROTEOMICS; TANDEM MASS SPECTROMETRY; VACCINES, SYNTHETIC;

EID: 84926416120     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2015.02.055     Document Type: Article

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