In vitro chondrocyte behavior on porous biodegradable poly (e-caprolactone)/polyglycolic acid scaffolds for articular chondrocyte adhesion and proliferation

Journal of Biomaterials Science, Polymer Edition

Volumn 26, Issue 7, 2015, Pages 401-419

  Jonnalagadda, John B ^a   Rivero, Iris V ^b   Dertien, Janet S ^c  

^a Department of Electrical and Computer Engineering   (United States)

^b Iowa State University of Science and Technology   (United States)

^c TEXAS TECH UNIVERSITY   (United States)

Author keywords

Articular cartilage; Chondrogenesis; Poly(e caprolactone); Poly(glycolic acid); Scaffolds; Tissue engineering

Indexed keywords

ADHESION; ASSAYS; BODY FLUIDS; CARTILAGE; CELL CULTURE; CELL PROLIFERATION; CELLS; COMPRESSION MOLDING; CYTOLOGY; ETHYLENE; POLYETHYLENE OXIDES; PORE SIZE; POROSITY; REPAIR; SCAFFOLDS; SCANNING ELECTRON MICROSCOPY; TISSUE; TISSUE ENGINEERING;

ARTICULAR CARTILAGE REPAIR; ARTICULAR CARTILAGES; CHONDROGENESIS; HUMAN ARTICULAR CARTILAGE; MORPHOLOGICAL ANALYSIS; MORPHOLOGICAL PROPERTIES; POLY(E-CAPROLACTONE); POLY(GLYCOLIC ACID);

SCAFFOLDS (BIOLOGY);

GLYCOSAMINOGLYCAN; MACROGOL; POLYCAPROLACTONE; POLYGLYCOLIC ACID; BIODEGRADABLE PLASTIC; POLYESTER;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; BIODEGRADABILITY; BOVINAE; CARTILAGE CELL; CELL ADHESION; CELL CULTURE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHONDROGENESIS; DNA DETERMINATION; IN VITRO STUDY; NONHUMAN; POROSITY; PRIORITY JOURNAL; PROTEIN SECRETION; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING; TISSUE SCAFFOLD; WATER TRANSPORT; YOUNG MODULUS; ANIMAL; BIOSYNTHESIS; BOVINE; CELL SHAPE; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; COMPRESSIVE STRENGTH; CYTOLOGY; EXTRACELLULAR MATRIX; MATERIALS TESTING; MECHANICS; METABOLISM; PHYSICAL CHEMISTRY; SECRETION (PROCESS); ULTRASTRUCTURE;

BOVINAE;

ANIMALS; BIODEGRADABLE PLASTICS; CARTILAGE, ARTICULAR; CATTLE; CELL ADHESION; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; COMPRESSIVE STRENGTH; EXTRACELLULAR MATRIX; GLYCOSAMINOGLYCANS; MATERIALS TESTING; MECHANICAL PHENOMENA; MICROSCOPY, ELECTRON, SCANNING; PHYSICOCHEMICAL PHENOMENA; POLYESTERS; POLYGLYCOLIC ACID; POROSITY; TISSUE SCAFFOLDS;

EID: 84926415850     PISSN: 09205063     EISSN: 15685624     Source Type: Journal    
DOI: 10.1080/09205063.2015.1015864     Document Type: Article

References (50)

1. Fox AJS, Bedi A, Rodeo SA. The basic science of articular cartilage: structure, composition, and function. Sports Health. 2009; 1: 461-468.
2. Roughley PJ. The structure and function of cartilage proteoglycans. Eur. Cell Mater. 2006; 12: 92-101.
3. Neves SC, Moreira Teixeir LS, Moroni L, Reis RL, Van Blitterswijk CA, Alves NM, Karperien M, Mano JF. Chitosan/poly(ε-caprolactone) blend scaffolds for cartilage repair. Biomaterials. 2011; 32: 1068-1079.
4. Dhandayuthapani B, Yoshida Y, Maekawa T, Kumar DS. Polymeric scaffolds in tissue engineering application: a review. Int. J. Polm. Sci. 2011; 2011: 1-19.
5. Lien SM, Ko LY, Huang TJ. Effect of pore size on ECM secretion and cell growth in gelatin scaffold for articular cartilage tissue engineering. Acta Biomater. 2009; 5: 670-679.
6. Ikada Y. Challenges in tissue engineering. J. R. Soc. Interface. 2006; 3: 589-601.
7. Griffon DJ, Sedighi MR, Schaeffer DV, Eurell JA, Johnson AL. Chitosan scaffolds: interconnective pore size and cartilage engineering. Acta Biomater. 2006; 2: 313-320.
8. Puppi D, Chiellini F, Piras AM, Chiellini E. Polymeric materials for bone and cartilage repair. Prog. Polym. Sci. 2010; 35: 403-440.
9. Jeong CG, Hollister SJ. Mechanical and biochemical assessments of three-dimensional poly(1, 8-octanediol-co-citrate) scaffold pore shape and permeability effects on in vitrochondrogenesis using primary chondrocytes. Tissue Eng. Part A. 2010; 16: 3759-3768.
10. Vial X, Andreopoulos FM. Novel biomaterials for cartilage tissue engineering. Curr. Rheumatol. Rev. 2009; 5: 51-57.
11. Rezwan K, Chen QZ, Blaker JJ, Boccaccini AR. Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering. Biomaterials. 2006; 27: 3413-3431.
12. Gunatillake PA, Adhikari R. Biodegradable synthetic polymers for tissue engineering. Eur. Cell Mater. 2003; 5: 1-16.
13. Wan Y, Wu H, Cao X, Dalai S. Compressive mechanical properties and biodegradability of porous poly(caprolactone)/chitosan scaffolds. Polym. Degrad. Stab. 2008; 93: 1736-1741.
14. Cao T, Ho KH, Teoh SH. Scaffold design and in vitro study of osteochondral coculture in a three-dimensional porous polycaprolactone scaffold fabricated by fused deposition modeling. Tissue Eng. 2003; 9: S103-S112.
15. Hoque ME, San WY, Wei F, Li S, Huang MH, Vert M, Hutmacher DW. Processing of polycaprolactone and polycaprolactone-based copolymers into 3d scaffolds, and their cellular responses. Tissue Eng. Part A. 2009; 15: 3013-3024.
16. Zhu Y, Gao C, Liu X, Shen J. Surface modification of polycaprolactone membrane via aminolysis and biomacromolecule immobilization for promoting cytocompatibility of human endothelial cells. Biomacromolecules. 2002; 3: 1312-1319.
17. Aghdam RM, Najarian S, Shakhesi S, Khanlari S, Shaabani K, Sharifi S. Investigating the effect of PGA on physical and mechanical properties of electrospun PCL/PGA blend nanofibers. J. Appl. Polym. Sci. 2012; 124: 123-131.
18. Ishaug-Riley SL, Okun LE, Prado G, Applegate MA, Ratcliffe A. Human articular chondrocyte adhesion and proliferation on synthetic biodegradable polymer films. Biomaterials. 1999; 20: 2245-2256.
19. Eastmond GC. Poly (ε-caprolactone) blends. Adv. Polym. Sci. 2000; 149: 59-223.
20. Woodward SC, Brewer PS, Moatamed F, Schindler A, Pitt CG. The intracellular degradation of poly (e-caprolactone). J. Biomed. Mater. Res. 1985; 19: 437-444.
21. Sabir MI, Xu X, Li L. A review on biodegradable polymeric materials for bone tissue engineering applications. J. Mater. Sci. 2009; 44: 5713-5724.
22. Otten JE, Wiedmann-Al-Ahmad M, Jahnke H, Pelz K. Bacterial colonization on different suture materials-a potential risk for intraoral dentoalveolar surgery. J. Biomed. Mater. Res. B. 2005; 74B: 627-635.
23. Bramfeldt H, Vermette P. Enhanced smooth muscle cell adhesion and proliferation on protein-modified polycaprolactone-based copolymers. J. Biomed. Mater. Res. A. 2009; 88A: 520-530.
24. Smith, AP, Ade H, Koch CC, Spontak RJ. Solid-state blending of polymers by cryogenic mechanical alloying. Mat. Res. Soc. Symp. Proc. 2000; 629: FF6.9.1-FF6.9.6.
25. Allaf RM, Rivero IV. Fabrication and characterization of interconnected porous biodegradable poly(ε-caprolactone) load bearing scaffolds. J. Mater. Sci. Mater. Med. 2011; 22: 1843-1853.
26. Allaf RM, Rivero IV, Abidi N, Ivanov IN. Porous poly(ε-caprolactone) scaffolds for load-bearing tissue regeneration: solventless fabrication and characterization. J. Biomed. Mater. Res. Part B. 2013; 101B: 1050-1060.
27. Reignier J, Huneault MA. Preparation of interconnected poly(ε-caprolactone) porous scaffolds by a combination of polymer and salt particulate leaching. Polymer. 2006; 47: 4703-4717.
28. Ghosh S, Viana JC, Reis RL, Mano JF. The double porogen approach as a new technique for the fabrication of interconnected poly(L-lactic acid) and starch based biodegradable scaffolds. J. Mater. Sci. Mater. Med. 2007; 18: 185-193.
29. Lebourg M, Anton JS, Gomez Ribelles JL. Porous membranes of PLLA-PCL blend for tissue engineering applications. Eur. Polym. J. 2008; 44: 2207-2218.
30. ASTM F2313-10. Standard specification for poly(glycolide) and poly(glycolide-co-lactide) resins for surgical implants with mole fractions greater than or equal to 70% glycolide. West Conshohocken, PA: ASTM International 2010.
31. Jonnalagadda JB, Rivero IV. Effect of cryomilling times on the resultant properties of porous biodegradable poly(e-caprolactone)/poly(glycolic acid) scaffolds for articular cartilage tissue engineering. J. Mech. Behav. Biomed. Mater. 2014; 40: 33-41.
32. Oh SH, Park IK, Kim JM, Lee JH. In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method. Biomaterials. 2007; 28: 1664-1671.
33. Pan Z, Ding J. Poly(lactide-co-glycolide) porous scaffolds for tissue engineering and regenerative medicine. Interface Focus. 2012; 2: 366-377.
34. Zhao J, Duan K, Zhang JW, Guo LY, Weng J. Preparation of highly interconnected porous hydroxyapatite scaffolds by chitin gel-casting. Mater. Sci. Eng. C. 2011; 31: 697-701.
35. Liu DM. Influence of porosity and pore size on the compressive strength of porous hydroxyapatite ceramic. Ceram. Int. 1197; 23: 135-139.
36. Kempson GE. Mechanical properties of articular cartilage. 2nd ed. Kent: Pitman; 1979.
37. Boschetti F, Pennati G, Gervaso F, Peretti GM, Dubini G. Biomechanical properties of human articular cartilage under compressive loads. Biorheology. 2004; 41: 159-166.
38. Barker MK, Seedhom BB. The relationship of the compressive modulus of articular cartilage with its deformation response to cyclic loading: does cartilage optimize its modulus so as to minimize the strains arising in it due to the prevalent loading regime? Rheumatology. 2001; 40: 274-284.
39. Shepherd DE, Seedhom BB. A technique for measuring the compressive modulus of articular cartilage under physiological loading rates with preliminary results. Proc. Inst. Mech. Eng. H. 1997; 211: 155-165.
40. Zhu YG, Li ZQ, Zhang D, Tanimoto T. Structural changes in poly(ethylene terephthalate) induced by cryomilling and ambimilling. J. Polym. Sci., Part B: Polym. Phys. 2006; 44: 986-993.
41. Liu L, Wang Y, Guo S, Wang Z, Wang W. Porous polycaprolactone/nanohydroxyapatite tissue engineering scaffolds fabricated by combining NaCl and PEG as co-porogens: structure, property, and chondrocyte-scaffold interaction in vitro. J. Biomed. Mater. Res. Part B. 2012; 100B: 956-966.
42. Lampin M, Warocquier-Clérout R, Legris C, Degrange M, Sigot-Luizard MF. Correlation between substratum roughness and wettability, cell adhesion, and cell migration. J. Biomed. Mater. Res. 1997; 36: 99-108.
43. Chang G, Absolom DR, Strong AB, Stubley GD, Zingg W. Physical and hydrodynamic factors a!ecting erythrocyte adhesion to polymer surfaces. J. Biomed. Mater. Res. 1998; 22: 13-29.
44. Olivieri MP, Kittle KH, Tweden KS, Loomis RE. Comparative biophysical study of adsorbed calf serum, fetal bovine serum and mussel adhesive protein films. Biomaterials. 1992; 13: 201-208.
45. Boyan BD, Hummert TW, Dean DD, Schwartz Z. Role of material surfaces in regulating bone and cartilage cell response. Biomaterials. 1996; 17: 137-146.
46. von der Mark K, Gauss V, von der Mark H, Müller P. Relationship between cell shape and type of collagen synthesised as chondrocytes lose their cartilage phenotype in culture. Nature. 1977; 267: 531-532.
47. Woodfield TB, Miot S, Martin I, van Blitterswijk CA, Riesle J. The regulation of expanded human nasal chondrocyte re-differentiation capacity by substrate composition and gas plasma surface modification. Biomaterials. 2006; 27: 1043-1053.
48. Barry JJ, Gidda HS, Scotchford CA, Howdle SM. Porous methacrylate scaffolds: supercritical fluid fabrication and in vitro chondrocyte responses. Biomaterials. 2004; 25: 3559-3568.
49. Shakibaei M, Schulze-Tanzil G, de Souza P, John T, Rahmanzadeh M, Rahmanzadeh R, Merker HJ. Inhibition of mitogen-activated protein kinase kinase induces apoptosis of human chondrocytes. J. Biol. Chem. 2001; 276: 13289-13294.
50. Svoboda KK. Chondrocyte-matrix attachment complexes mediate survival and differentiation. Microsc. Res. Tech. 1998; 43: 111-122.