Development of Acyl Protein Thioesterase 1 (APT1) Inhibitor Palmostatin B That Revert Unregulated H/N-Ras Signaling

Concepts and Case Studies in Chemical Biology

Volumn 9783527336111, Issue , 2014, Pages 123-140

  Dekker, Frank J ^a   Vartak, Nachiket ^b   Hedberg, Christian ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Acyl protein thioesterase 1 (APT1) inhibitors; Cancer signaling; H N Ras signaling; Live cell imaging; Palmostatin B; Protein palmitoylation; Protein structure similarity clustering (PSSC); Reverse chemical genetics studies; Rous sarcoma oncogene cellular homolog (Src)

Indexed keywords

BIOSYNTHESIS; CANCER CELLS; CELL SIGNALING; CHROMOSOMES; CYTOLOGY; DISEASES; FLUORESCENCE IMAGING; SIGNALING; TUMORS;

ACYL PROTEIN THIOESTERASE 1 INHIBITOR; CANCER SIGNALING; CELLULARS; CHEMICAL GENETICS; CLUSTERINGS; GENETIC STUDIES; H/N-RAT SARCOMA SIGNALING; LIVE-CELL IMAGING; PALMOSTATIN B; PROTEIN PALMITOYLATION; PROTEIN STRUCTURE SIMILARITY CLUSTERING; PROTEINS STRUCTURES; REVERSE CHEMICAL GENETIC STUDY; ROUS SARCOMA ONCOGENE CELLULAR HOMOLOGUE (SRC); STRUCTURE SIMILARITY; THIOESTERASES;

PROTEINS;

EID: 84926405581     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527687503.ch8     Document Type: Chapter

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