메뉴 건너뛰기




Volumn 11, Issue 3, 2015, Pages

Model-based Traction Force Microscopy Reveals Differential Tension in Cellular Actin Bundles

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; IMAGE ENHANCEMENT; INTERFACES (MATERIALS); INVERSE PROBLEMS; PROTEINS; TRACTION (FRICTION);

EID: 84926343527     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004076     Document Type: Article
Times cited : (91)

References (57)
  • 1
    • 58049191448 scopus 로고    scopus 로고
    • Environmental sensing through focal adhesions
    • Geiger B., Spatz J. P., Bershadsky A. D., Environmental sensing through focal adhesions. Nat. Rev. Mol. Cell Biol. 10, 21–33 (2009). doi: 10.1038/nrm2593 19197329
    • (2009) Nat. Rev. Mol. Cell Biol , vol.10 , pp. 21-33
    • Geiger, B.1    Spatz, J.P.2    Bershadsky, A.D.3
  • 2
    • 79960637431 scopus 로고    scopus 로고
    • a. Dynamic molecular processes mediate cellular mechanotransduction
    • Hoffman B. D., Grashoff C., Schwartz M., a. Dynamic molecular processes mediate cellular mechanotransduction. Nature 475, 316–23 (2011). doi: 10.1038/nature10316 21776077
    • (2011) Nature , vol.475 , pp. 316-323
    • Hoffman, B.D.1    Grashoff, C.2    Schwartz, M.3
  • 3
    • 84869111112 scopus 로고    scopus 로고
    • United we stand—integrating the actin cytoskeleton and cell-matrix adhesions in cellular mechanotransduction
    • Schwarz U. S., Gardel M. L., United we stand—integrating the actin cytoskeleton and cell-matrix adhesions in cellular mechanotransduction. J. Cell Sci. (2012). doi: 10.1242/jcs.093716 22797913
    • (2012) J. Cell Sci
    • Schwarz, U.S.1    Gardel, M.L.2
  • 4
    • 84891533398 scopus 로고    scopus 로고
    • Actin dynamics, architecture, and mechanics in cell motility
    • Blanchoin L., Boujemaa-Paterski R., Sykes C., Plastino J., Actin dynamics, architecture, and mechanics in cell motility. Physiol. Rev. 94, 235–63 (2014). doi: 10.1152/physrev.00018.2013 24382887
    • (2014) Physiol. Rev , vol.94 , pp. 235-263
    • Blanchoin, L.1    Boujemaa-Paterski, R.2    Sykes, C.3    Plastino, J.4
  • 6
    • 33646386142 scopus 로고    scopus 로고
    • Stress fibers are generated by two distinct actin assembly mechanisms in motile cells
    • Hotulainen P., Lappalainen P., Stress fibers are generated by two distinct actin assembly mechanisms in motile cells. J. Cell Biol. 173, 383–94 (2006). doi: 10.1083/jcb.200511093 16651381
    • (2006) J. Cell Biol , vol.173 , pp. 383-394
    • Hotulainen, P.1    Lappalainen, P.2
  • 7
    • 84903776336 scopus 로고    scopus 로고
    • Stressing the limits of focal adhesion mechanosensitivity
    • Oakes P. W., Gardel M. L., Stressing the limits of focal adhesion mechanosensitivity. Curr. Opin. Cell Biol. 30C, 68–73 (2014). doi: 10.1016/j.ceb.2014.06.003 24998185
    • (2014) Curr. Opin. Cell Biol , vol.30C , pp. 68-73
    • Oakes, P.W.1    Gardel, M.L.2
  • 8
    • 0033066120 scopus 로고    scopus 로고
    • Stresses at the cell-to-substrate interface during locomotion of fibroblasts
    • Dembo M., Wang Y. L., Stresses at the cell-to-substrate interface during locomotion of fibroblasts. Biophys. J. 76, 2307–16 (1999). doi: 10.1016/S0006-3495(99)77386-8 10096925
    • (1999) Biophys. J , vol.76 , pp. 2307-2316
    • Dembo, M.1    Wang, Y.L.2
  • 9
    • 0036083584 scopus 로고    scopus 로고
    • Traction fields, moments, and strain energy that cells exert on their surroundings
    • Butler J. P., Tolić-Nørrelykke I. M., Fabry B., Fredberg J. J., Traction fields, moments, and strain energy that cells exert on their surroundings. Am. J. Physiol. Cell Physiol. 282, C595–605 (2002). doi: 10.1152/ajpcell.00270.2001 11832345
    • (2002) Am. J. Physiol. Cell Physiol , vol.282 , pp. 595-605
    • Butler, J.P.1    Tolić-Nørrelykke, I.M.2    Fabry, B.3    Fredberg, J.J.4
  • 10
    • 37749000819 scopus 로고    scopus 로고
    • High resolution traction force microscopy based on experimental and computational advances
    • Sabass B., Gardel M. L., Waterman C. M., Schwarz U. S., High resolution traction force microscopy based on experimental and computational advances. Biophys. J. 94, 207–20 (2008). doi: 10.1529/biophysj.107.113670 17827246
    • (2008) Biophys. J , vol.94 , pp. 207-220
    • Sabass, B.1    Gardel, M.L.2    Waterman, C.M.3    Schwarz, U.S.4
  • 11
    • 0037452695 scopus 로고    scopus 로고
    • Cells lying on a bed of microneedles: an approach to isolate mechanical force
    • Tan J. L., et al. Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc. Natl. Acad. Sci. U. S. A. 100, 1484–1489 (2003). doi: 10.1073/pnas.0235407100 12552122
    • (2003) Proc. Natl. Acad. Sci. U. S. A , vol.100 , pp. 1484-1489
    • Tan, J.L.1
  • 12
    • 14044270846 scopus 로고    scopus 로고
    • Force mapping in epithelial cell migration
    • Du Roure O., et al. Force mapping in epithelial cell migration. Proc. Natl. Acad. Sci. U. S. A. 102, 2390–2395 (2005). doi: 10.1073/pnas.0408482102 15695588
    • (2005) Proc. Natl. Acad. Sci. U. S. A , vol.102 , pp. 2390-2395
    • Du Roure, O.1
  • 13
    • 77954486800 scopus 로고    scopus 로고
    • Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics
    • Grashoff C., et al. Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics. Nature 466, 263–266 (2010). doi: 10.1038/nature09198 20613844
    • (2010) Nature , vol.466 , pp. 263-266
    • Grashoff, C.1
  • 14
    • 84856440471 scopus 로고    scopus 로고
    • Visualizing mechanical tension across membrane receptors with a fluorescent sensor
    • Stabley D. R., Jurchenko C., Marshall S. S., Salaita K. S., Visualizing mechanical tension across membrane receptors with a fluorescent sensor. Nat. Methods 9, (2012).
    • (2012) Nat. Methods , vol.9
    • Stabley, D.R.1    Jurchenko, C.2    Marshall, S.S.3    Salaita, K.S.4
  • 15
    • 84884243072 scopus 로고    scopus 로고
    • Molecular tension sensors report forces generated by single integrin molecules in living cells
    • Morimatsu M., Mekhdjian A. H., Adhikari A. S., Dunn A. R., Molecular tension sensors report forces generated by single integrin molecules in living cells. Nano Lett. 13, 3985–9 (2013). doi: 10.1021/nl4005145 23859772
    • (2013) Nano Lett , vol.13 , pp. 3985-3989
    • Morimatsu, M.1    Mekhdjian, A.H.2    Adhikari, A.S.3    Dunn, A.R.4
  • 16
    • 84925512079 scopus 로고    scopus 로고
    • A DNA-based molecular probe for optically reporting cellular traction forces
    • Blakely B. L., et al. A DNA-based molecular probe for optically reporting cellular traction forces. Nat. Methods 11: 1229–32 (2014). doi: 10.1038/nmeth.3145 25306545
    • (2014) Nat. Methods , vol.11 , pp. 1229-1232
    • Blakely, B.L.1
  • 17
    • 84907861921 scopus 로고    scopus 로고
    • Nanoparticle Tension Probes Patterned at the Nanoscale: Impact of Integrin Clustering on Force Transmission
    • Liu Y., et al. Nanoparticle Tension Probes Patterned at the Nanoscale: Impact of Integrin Clustering on Force Transmission. Nano Lett. 14, 5539–46 (2014). doi: 10.1021/nl501912g 25238229
    • (2014) Nano Lett , vol.14 , pp. 5539-5546
    • Liu, Y.1
  • 18
    • 84926293396 scopus 로고    scopus 로고
    • DNA-based digital tension probes reveal integrin forces during early cell adhesion
    • Zhang Y., Ge C., Zhu C., Salaita K., DNA-based digital tension probes reveal integrin forces during early cell adhesion. Nat. Commun. 5, 5167 (2014). doi: 10.1038/ncomms6167 25342432
    • (2014) Nat. Commun , vol.5 , pp. 5167
    • Zhang, Y.1    Ge, C.2    Zhu, C.3    Salaita, K.4
  • 19
    • 58249086114 scopus 로고    scopus 로고
    • Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed
    • Gardel M. L., et al. Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed. J. Cell Biol. 183, 999–1005 (2008). doi: 10.1083/jcb.200810060 19075110
    • (2008) J. Cell Biol , vol.183 , pp. 999-1005
    • Gardel, M.L.1
  • 20
    • 33646179573 scopus 로고    scopus 로고
    • Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics
    • Kumar S., et al. Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. Biophys. J. 90, 3762–3773 (2006). doi: 10.1529/biophysj.105.071506 16500961
    • (2006) Biophys. J , vol.90 , pp. 3762-3773
    • Kumar, S.1
  • 21
    • 0035002155 scopus 로고    scopus 로고
    • Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates
    • Balaban N. Q., et al. Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates. Nat. Cell Biol. 3, 466–72 (2001). 11331874
    • (2001) Nat. Cell Biol , vol.3 , pp. 466-472
    • Balaban, N.Q.1
  • 22
    • 77951545840 scopus 로고    scopus 로고
    • Optimization of traction force microscopy for micron-sized focal adhesions
    • Stricker J., Sabass B., Schwarz U. S., Gardel M. L., Optimization of traction force microscopy for micron-sized focal adhesions. J. Phys. Condens. Matter 22, 194104 (2010). doi: 10.1088/0953-8984/22/19/194104 20523913
    • (2010) J. Phys. Condens. Matter , vol.22 , pp. 194104
    • Stricker, J.1    Sabass, B.2    Schwarz, U.S.3    Gardel, M.L.4
  • 23
    • 67650541328 scopus 로고    scopus 로고
    • Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization
    • Colombelli J., et al. Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization. J. Cell Sci. 122, 1665–1679 (2009). doi: 10.1242/jcs.042986 19401336
    • (2009) J. Cell Sci , vol.122 , pp. 1665-1679
    • Colombelli, J.1
  • 24
    • 78349269956 scopus 로고    scopus 로고
    • Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery
    • Tanner K., Boudreau A., Bissell M. J., Kumar S., Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery. Biophys. J. 99, 2775–83 (2010). doi: 10.1016/j.bpj.2010.08.071 21044574
    • (2010) Biophys. J , vol.99 , pp. 2775-2783
    • Tanner, K.1    Boudreau, A.2    Bissell, M.J.3    Kumar, S.4
  • 25
    • 84880673342 scopus 로고    scopus 로고
    • Vinculin tension distributions of individual stress fibers within cell-matrix adhesions
    • Chang C.-W., Kumar S., Vinculin tension distributions of individual stress fibers within cell-matrix adhesions. J. Cell Sci. 126, 3021–30 (2013). doi: 10.1242/jcs.119032 23687380
    • (2013) J. Cell Sci , vol.126 , pp. 3021-3030
    • Chang, C.-W.1    Kumar, S.2
  • 26
    • 84860706299 scopus 로고    scopus 로고
    • Scaling of Traction Forces with the Size of Cohesive Cell Colonies
    • Mertz A., et al. Scaling of Traction Forces with the Size of Cohesive Cell Colonies. Phys. Rev. Lett. 108, 1–5 (2012). doi: 10.1103/PhysRevLett.108.198101 23003091
    • (2012) Phys. Rev. Lett , vol.108 , pp. 1-5
    • Mertz, A.1
  • 27
    • 84891442243 scopus 로고    scopus 로고
    • Polarizing cytoskeletal tension to induce leader cell formation during collective cell migration
    • Rausch S., et al. Polarizing cytoskeletal tension to induce leader cell formation during collective cell migration. Biointerphases 8, 32 (2013). doi: 10.1186/1559-4106-8-32 24706149
    • (2013) Biointerphases , vol.8 , pp. 32
    • Rausch, S.1
  • 28
    • 79957451087 scopus 로고    scopus 로고
    • Collective cell guidance by cooperative intercellular forces
    • Tambe D. T., et al. Collective cell guidance by cooperative intercellular forces. Nat. Mater. 10, 469–475 (2011). doi: 10.1038/nmat3025 21602808
    • (2011) Nat. Mater , vol.10 , pp. 469-475
    • Tambe, D.T.1
  • 29
    • 84901989971 scopus 로고    scopus 로고
    • Dynamics of cell shape and forces on micropatterned substrates predicted by a cellular Potts model
    • Albert P. J., Schwarz U. S., Dynamics of cell shape and forces on micropatterned substrates predicted by a cellular Potts model. Biophys. J. 106, 2340–52 (2014). doi: 10.1016/j.bpj.2014.04.036 24896113
    • (2014) Biophys. J , vol.106 , pp. 2340-2352
    • Albert, P.J.1    Schwarz, U.S.2
  • 30
    • 84907324202 scopus 로고    scopus 로고
    • Geometry Regulates Traction Stresses in Adherent Cells
    • Oakes P. W., Banerjee S., Marchetti M. C., Gardel M. L., Geometry Regulates Traction Stresses in Adherent Cells. Biophys. J. 107, 825–833 (2014). doi: 10.1016/j.bpj.2014.06.045 25140417
    • (2014) Biophys. J , vol.107 , pp. 825-833
    • Oakes, P.W.1    Banerjee, S.2    Marchetti, M.C.3    Gardel, M.L.4
  • 31
    • 68749087424 scopus 로고    scopus 로고
    • Effect of Adhesion Geometry and Rigidity on Cellular Force Distributions
    • Bischofs I., Schmidt S., Schwarz U., Effect of Adhesion Geometry and Rigidity on Cellular Force Distributions. Phys. Rev. Lett. 103, 048101 (2009). doi: 10.1103/PhysRevLett.103.048101 19659402
    • (2009) Phys. Rev. Lett , vol.103 , pp. 048101
    • Bischofs, I.1    Schmidt, S.2    Schwarz, U.3
  • 32
    • 0036708449 scopus 로고    scopus 로고
    • Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization
    • Schwarz U. S., et al. Calculation of forces at focal adhesions from elastic substrate data: the effect of localized force and the need for regularization. Biophys. J. 83, 1380–94 (2002). doi: 10.1016/S0006-3495(02)73909-X 12202364
    • (2002) Biophys. J , vol.83 , pp. 1380-1394
    • Schwarz, U.S.1
  • 33
    • 84902987002 scopus 로고    scopus 로고
    • High-resolution traction force microscopy
    • Plotnikov S. V, Sabass B., Schwarz U. S., Waterman C. M., High-resolution traction force microscopy. Methods Cell Biol. 123, 367–94 (Elsevier Inc., 2014). doi: 10.1016/B978-0-12-420138-5.00020-3 24974038
    • (2014) Methods Cell Biol , vol.123 , pp. 367-394
    • Plotnikov, S.V.1    Sabass, B.2    Schwarz, U.S.3    Waterman, C.M.4
  • 34
    • 0000570697 scopus 로고
    • Analysis of discrete ill-posed problems by means of the L-curve
    • Hansen P. C., Analysis of discrete ill-posed problems by means of the L-curve. SIAM 34, 561–580 (1992). doi: 10.1137/1034115
    • (1992) SIAM , vol.34 , pp. 561-580
    • Hansen, P.C.1
  • 35
    • 0029880446 scopus 로고    scopus 로고
    • Imaging the Traction Stresses Exerted by Locomoting Cells with the Elastic Substratum Method
    • Dembo M., Oliver T., Imaging the Traction Stresses Exerted by Locomoting Cells with the Elastic Substratum Method. Biophys. J. 70, 2008–2022 (1996). doi: 10.1016/S0006-3495(96)79767-9 8785360
    • (1996) Biophys. J , vol.70 , pp. 2008-2022
    • Dembo, M.1    Oliver, T.2
  • 36
    • 55949123735 scopus 로고    scopus 로고
    • Filamentous network mechanics and active contractility determine cell and tissue shape
    • Bischofs I. B., Klein F., Lehnert D., Bastmeyer M., Schwarz U. S., Filamentous network mechanics and active contractility determine cell and tissue shape. Biophys. J. 95, 3488–96 (2008). doi: 10.1529/biophysj.108.134296 18599642
    • (2008) Biophys. J , vol.95 , pp. 3488-3496
    • Bischofs, I.B.1    Klein, F.2    Lehnert, D.3    Bastmeyer, M.4    Schwarz, U.S.5
  • 37
    • 80055106732 scopus 로고    scopus 로고
    • Preparation of complaint matrices for quantifying cellular contraction
    • Aratyn-Schaus Y., Oakes P. W., Stricker J., Winter S. P., Gardel M. L., Preparation of complaint matrices for quantifying cellular contraction. J. Vis. Exp. 1–6 (2010). doi: 10.3791/2173 21178972
    • (2010) J. Vis. Exp , pp. 1-6
    • Aratyn-Schaus, Y.1    Oakes, P.W.2    Stricker, J.3    Winter, S.P.4    Gardel, M.L.5
  • 38
    • 19944428596 scopus 로고    scopus 로고
    • Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion
    • Yeung T., et al. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskeleton 60, 24–34 (2005). doi: 10.1002/cm.20041 15573414
    • (2005) Cell Motil. Cytoskeleton , vol.60 , pp. 24-34
    • Yeung, T.1
  • 39
    • 79960325552 scopus 로고    scopus 로고
    • Spatiotemporal constraints on the force-dependent growth of focal adhesions
    • Stricker J., Aratyn-Schaus Y., Oakes P. W., Gardel M. L., Spatiotemporal constraints on the force-dependent growth of focal adhesions. Biophys. J. 100, 2883–93 (2011). doi: 10.1016/j.bpj.2011.05.023 21689521
    • (2011) Biophys. J , vol.100 , pp. 2883-2893
    • Stricker, J.1    Aratyn-Schaus, Y.2    Oakes, P.W.3    Gardel, M.L.4
  • 40
    • 33748993682 scopus 로고    scopus 로고
    • A bio-chemo-mechanical model for cell contractility
    • Deshpande V. S., McMeeking R. M., Evans A. G., A bio-chemo-mechanical model for cell contractility. Proc. Natl. Acad. Sci. U. S. A. 103, 14015–20 (2006). doi: 10.1073/pnas.0605837103 16959880
    • (2006) Proc. Natl. Acad. Sci. U. S. A , vol.103 , pp. 14015-14020
    • Deshpande, V.S.1    McMeeking, R.M.2    Evans, A.G.3
  • 41
    • 35448972822 scopus 로고    scopus 로고
    • A model for the contractility of the cytoskeleton including the effects of stress-fibre formation and dissociation
    • Deshpande V. S., McMeeking R. M., Evans A. G., A model for the contractility of the cytoskeleton including the effects of stress-fibre formation and dissociation. Proc. R. Soc. A Math. Phys. Eng. Sci. 463, 787–815 (2007). doi: 10.1098/rspa.2006.1793
    • (2007) Proc. R. Soc. A Math. Phys. Eng. Sci , vol.463 , pp. 787-815
    • Deshpande, V.S.1    McMeeking, R.M.2    Evans, A.G.3
  • 42
    • 40749124949 scopus 로고    scopus 로고
    • The simulation of stress fibre and focal adhesion development in cells on patterned substrates
    • Pathak A., Deshpande V. S., McMeeking R. M., Evans A. G., The simulation of stress fibre and focal adhesion development in cells on patterned substrates. J. R. Soc. Interface 5, 507–524 (2008). doi: 10.1098/rsif.2007.1182 17939980
    • (2008) J. R. Soc. Interface , vol.5 , pp. 507-524
    • Pathak, A.1    Deshpande, V.S.2    McMeeking, R.M.3    Evans, A.G.4
  • 43
    • 23944432418 scopus 로고    scopus 로고
    • A theoretical description of elastic pillar substrates in biophysical experiments
    • Mohrdieck C., et al. A theoretical description of elastic pillar substrates in biophysical experiments. Chemphyschem 6, 1492–8 (2005). doi: 10.1002/cphc.200500109 16082672
    • (2005) Chemphyschem , vol.6 , pp. 1492-1498
    • Mohrdieck, C.1
  • 44
    • 84867002938 scopus 로고    scopus 로고
    • Structural Mechanics Based Model for the Force-Bearing Elements Within the Cytoskeleton of a Cell Adhered on a Bed of Posts
    • Pathak A., Chen C. S., Evans A. G., McMeeking R. M., Structural Mechanics Based Model for the Force-Bearing Elements Within the Cytoskeleton of a Cell Adhered on a Bed of Posts. J. Appl. Mech. 79, 061020 (2012). doi: 10.1115/1.4006452
    • (2012) J. Appl. Mech , vol.79 , pp. 061020
    • Pathak, A.1    Chen, C.S.2    Evans, A.G.3    McMeeking, R.M.4
  • 45
    • 84856673859 scopus 로고    scopus 로고
    • Contractile network models for adherent cells
    • Guthardt Torres P., Bischofs I. B., Schwarz U. S., Contractile network models for adherent cells. Phys. Rev. E 85, 011913 (2012). doi: 10.1103/PhysRevE.85.011913 22400597
    • (2012) Phys. Rev. E , vol.85 , pp. 011913
    • Guthardt Torres, P.1    Bischofs, I.B.2    Schwarz, U.S.3
  • 46
    • 79960299436 scopus 로고    scopus 로고
    • Reconstitution of contractile actomyosin bundles
    • Thoresen T., Lenz M., Gardel M. L., Reconstitution of contractile actomyosin bundles. Biophys. J. 100, 2698–705 (2011). doi: 10.1016/j.bpj.2011.04.031 21641315
    • (2011) Biophys. J , vol.100 , pp. 2698-2705
    • Thoresen, T.1    Lenz, M.2    Gardel, M.L.3
  • 47
    • 84863205849 scopus 로고    scopus 로고
    • NIH Image to ImageJ: 25 years of image analysis
    • Schneider C. a, Rasband W. S., Eliceiri K. W., NIH Image to ImageJ: 25 years of image analysis. Nat. Methods 9, 671–675 (2012). doi: 10.1038/nmeth.2089 22930834
    • (2012) Nat. Methods , vol.9 , pp. 671-675
    • Schneider, C.1    Rasband, W.S.2    Eliceiri, K.W.3
  • 51
    • 84875633689 scopus 로고    scopus 로고
    • Assembly of non-contractile dorsal stress fibers requires α-actinin-1 and Rac1 in migrating and spreading cells
    • Kovac B., Teo J. L., Mäkelä T. P., Vallenius T., Assembly of non-contractile dorsal stress fibers requires α-actinin-1 and Rac1 in migrating and spreading cells. J. Cell Sci. 126, 263–273 (2013). doi: 10.1242/jcs.115063 23132927
    • (2013) J. Cell Sci , vol.126 , pp. 263-273
    • Kovac, B.1    Teo, J.L.2    Mäkelä, T.P.3    Vallenius, T.4
  • 52
    • 0036469826 scopus 로고    scopus 로고
    • Flexible substrata for the detection of cellular traction forces
    • Beningo K. a, Wang Y.-L., Flexible substrata for the detection of cellular traction forces. Trends Cell Biol. 12, 79–84 (2002). doi: 10.1016/S0962-8924(01)02205-X 11849971
    • (2002) Trends Cell Biol , vol.12 , pp. 79-84
    • Beningo, K.1    Wang, Y.-L.2
  • 53
    • 0037175402 scopus 로고    scopus 로고
    • The relationship between force and focal complex development
    • Galbraith C. G., Yamada K. M., Sheetz M. P., The relationship between force and focal complex development. J. Cell Biol. 159, 695–705 (2002). doi: 10.1083/jcb.200204153 12446745
    • (2002) J. Cell Biol , vol.159 , pp. 695-705
    • Galbraith, C.G.1    Yamada, K.M.2    Sheetz, M.P.3
  • 54
    • 56649084971 scopus 로고    scopus 로고
    • Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading
    • Dubin-Thaler B. J., et al. Quantification of cell edge velocities and traction forces reveals distinct motility modules during cell spreading. PLoS One 3, e3735 (2008). doi: 10.1371/journal.pone.0003735 19011687
    • (2008) PLoS One , vol.3 , pp. 3735
    • Dubin-Thaler, B.J.1
  • 55
    • 50849122034 scopus 로고    scopus 로고
    • Self-organized podosomes are dynamic mechanosensors
    • Collin O., et al. Self-organized podosomes are dynamic mechanosensors. Curr. Biol. 18, 1288–94 (2008). doi: 10.1016/j.cub.2008.07.046 18760605
    • (2008) Curr. Biol , vol.18 , pp. 1288-1294
    • Collin, O.1
  • 56
    • 78649717029 scopus 로고    scopus 로고
    • Measurement of mechanical tractions exerted by cells in three-dimensional matrices
    • Legant W. R., et al. Measurement of mechanical tractions exerted by cells in three-dimensional matrices. Nat. Methods 7, 969–71 (2010). doi: 10.1038/nmeth.1531 21076420
    • (2010) Nat. Methods , vol.7 , pp. 969-971
    • Legant, W.R.1
  • 57
    • 84872561011 scopus 로고    scopus 로고
    • Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
    • Legant W. R., et al. Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions. Proc. Natl. Acad. Sci. U. S. A. 110, 881–6 (2013). doi: 10.1073/pnas.1207997110 23277584
    • (2013) Proc. Natl. Acad. Sci. U. S. A , vol.110 , pp. 881-886
    • Legant, W.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.