MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation

Journal of Clinical Investigation

Volumn 125, Issue 4, 2015, Pages 1509-1522

  Li, Chang Jun ^a,b   Cheng, Peng ^a,c   Liang, Meng Ke ^a   Chen, Yu Si ^a   Lu, Qiong ^a   Wang, Jin Yu ^a   Xia, Zhu Ying ^a   Zhou, Hou De ^a   Cao, Xu ^b   Xie, Hui ^a   Liao, Er Yuan ^a   Luo, Xiang Hang ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIR; ANTAGOMIR 188; APTAMER; CALCEIN; FATTY ACID BINDING PROTEIN 4; HISTONE DEACETYLASE 9; LUCIFERASE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MICRORNA; MICRORNA 188; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; CARRIER PROTEIN; HDAC9 PROTEIN, MOUSE; HISTONE DEACETYLASE; MIRN188 MICRORNA, HUMAN; MIRN188 MICRORNA, MOUSE; OSTERIX PROTEIN, MOUSE; REPRESSOR PROTEIN; RICTOR PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ADIPOGENESIS; ADULT; AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BONE DEVELOPMENT; BONE MASS; BONE STRENGTH; CELL COUNT; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; GENE OVEREXPRESSION; GENE SEQUENCE; GENE SWITCHING; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIPID STORAGE; MALE; MOUSE; MUSCULOSKELETAL SYSTEM PARAMETERS; NONHUMAN; OSSIFICATION; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; TRABECULAR BONE; 3' UNTRANSLATED REGION; ADIPOCYTE; ADIPOSE TISSUE; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE DENSITY; BONE MARROW CELL; BONE REMODELING; CELL DIFFERENTIATION; COMPARATIVE STUDY; CYTOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OSTEOBLAST; OSTEOPOROSIS; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

3' UNTRANSLATED REGIONS; ADIPOCYTES; ADIPOSE TISSUE; AGING; ANIMALS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BONE DENSITY; BONE MARROW CELLS; BONE REMODELING; CARRIER PROTEINS; CELL DIFFERENTIATION; HISTONE DEACETYLASES; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MICRORNAS; MOLECULAR SEQUENCE DATA; OSTEOBLASTS; OSTEOCALCIN; OSTEOGENESIS; OSTEOPOROSIS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84926323667     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI77716     Document Type: Article

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