Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Dodbiba, Lorin ^a,b   Teichman, Jennifer ^a   Fleet, Andrew ^c   Thai, Henry ^c   Starmans, Maud H W ^d,e   Navab, Roya ^c   Chen, Zhuo ^a   Girgis, Hala ^f   Eng, Lawson ^c   Espin Garcia, Osvaldo ^d   Shen, Xiaowei ^d   Bandarchi, Bizhan ^c   Schwock, Joerg ^f   Tsao, Ming Sound ^c,f   El Zimaity, Hala ^c,f   Der, Sandy D ^c   Xu, Wei ^c,d   Bristow, Robert G ^a,c   Darling, Gail E ^f   Boutros, Paul C ^a,d,g   Ailles, Laurie E ^a,c   Liu, Geoffrey ^a,c,g   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

^e MAASTRICHT UNIVERSITY   (Netherlands)

^f TORONTO GENERAL HOSPITAL   (Canada)

^g UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUOROURACIL; KI 67 ANTIGEN; MESSENGER RNA; PACLITAXEL; PROTEIN P16; PROTEIN P53;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CHEMOTHERAPY; CANCER TISSUE; CHEMOSENSITIVITY; CONTROLLED STUDY; ESOPHAGEAL ADENOCARCINOMA; GASTRO ESOPHAGEAL JUNCTION ADENOCARCINOMA; HUMAN; HUMAN TISSUE; HYBRIDIZATION; IMMUNOHISTOCHEMISTRY; LOWER ESOPHAGUS SPHINCTER; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PROTEIN EXPRESSION; RNA EXTRACTION; SCID MOUSE; TUMOR XENOGRAFT; ANIMAL; DRUG SCREENING; ESOPHAGEAL NEOPLASMS; GASTROESOPHAGEAL JUNCTION; PATHOLOGY; STOMACH NEOPLASMS;

MUS;

ANIMALS; ESOPHAGEAL NEOPLASMS; ESOPHAGOGASTRIC JUNCTION; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; STOMACH NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84926318113     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121872     Document Type: Article

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